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List of works by Zbyněk Heger

17β-estradiol-containing liposomes as a novel delivery system for the antisense therapy of ER-positive breast cancer: An in vitro study on the MCF-7 cell line.

scientific article

3D-printed biosensor with poly(dimethylsiloxane) reservoir for magnetic separation and quantum dots-based immunolabeling of metallothionein

scientific article

A novel insight into the cardiotoxicity of antineoplastic drug doxorubicin.

scientific article published on 31 October 2013

A two-step protocol for isolation of influenza A (H7N7) virions and their RNA for PCR diagnostics based on modified paramagnetic particles.

scientific article

Advanced nanotechnologies in avian influenza: Current status and future trends - A review.

scientific article published on 07 July 2017

Alternative Synthesis Route of Biocompatible Polyvinylpyrrolidone Nanoparticles and Their Effect on Pathogenic Microorganisms.

scientific article published on 12 December 2016

Amino Acid Profiling of Zinc Resistant Prostate Cancer Cell Lines: Associations With Cancer Progression

scientific article published on 19 January 2017

An enzymatic assay based on luciferase Ebola virus-like particles for evaluation of virolytic activity of antimicrobial peptides.

scientific article

An insight into the complex roles of metallothioneins in malignant diseases with emphasis on (sub)isoforms/isoforms and epigenetics phenomena

scientific article

Anticarcinogenic Effect of Spices Due to Phenolic and Flavonoid Compounds-In Vitro Evaluation on Prostate Cells

scientific article published on 28 September 2017

Apoferritin applications in nanomedicine

scientific article

Apoferritin as an ubiquitous nanocarrier with excellent shelf life.

scientific article

Bioconjugation of peptides using advanced nanomaterials to examine their interactions in 3D printed flow-through device

scientific article published on 14 October 2015

Carbon dots based FRET for the detection of DNA damage.

scientific article published on 9 February 2017

Co-delivery of VP-16 and Bcl-2-targeted antisense on PEG-grafted oMWCNTs for synergistic in vitro anti-cancer effects in non-small and small cell lung cancer

scientific article

Comparative gene expression profiling of human metallothionein-3 up-regulation in neuroblastoma cells and its impact on susceptibility to cisplatin

scientific article published on 16 December 2017

Correction to “Alternative Synthesis Route of Biocompatible Polyvinylpyrrolidone Nanoparticles and Their Effect on Pathogenic Microorganisms”

scientific article published in 2021

Correction: The Zinc-Schiff Base-Novicidin Complex as a Potential Prostate Cancer Therapy

scientific article published in PLoS ONE

Cytochrome b5 plays a dual role in the reaction cycle of cytochrome P450 3A4 during oxidation of the anticancer drug ellipticine.

scientific article published on 4 July 2017

DNA-magnetic Particle Binding Analysis by Dynamic and Electrophoretic Light Scattering

scientific article published on 9 November 2017

Determination of common urine substances as an assay for improving prostate carcinoma diagnostics

scientific article published on 24 February 2014

Differences in Urinary Amino Acid Patterns in Individuals with Different Types of Urological Tumor Urinary Amino Acid Patterns as Markers of Urological Tumors.

scientific article published in March 2018

Differences in urinary proteins related to surgical margin status after radical prostatectomy

scientific article published in December 2015

Drug Sequestration in Lysosomes as One of the Mechanisms of Chemoresistance of Cancer Cells and the Possibilities of Its Inhibition

scientific article published on 20 June 2020

Effect of HPV on tumor expression levels of the most commonly used markers in HNSCC.

scientific article published on 14 December 2015

Electrochemical sensing of etoposide using carbon quantum dot modified glassy carbon electrode

scientific article published on 17 February 2016

Encapsulation of Doxorubicin in Furcellaran/Chitosan Nanocapsules by Layer-by-Layer Technique for Selectively Controlled Drug Delivery

scientific article published on 03 December 2019

Establishment of oral squamous cell carcinoma cell line and magnetic bead-based isolation and characterization of its CD90/CD44 subpopulations.

scientific article published on 3 August 2017

Evaluation of EGFR as a prognostic and diagnostic marker for head and neck squamous cell carcinoma patients

scientific article published on 21 July 2016

Exceptional release kinetics and cytotoxic selectivity of oxidised MWCNTs double-functionalised with doxorubicin and prostate-homing peptide

scientific article published on 03 May 2017

Exposure to 17β-Oestradiol Induces Oxidative Stress in the Non-Oestrogen Receptor Invertebrate Species Eisenia fetida

scientific article published on 22 December 2015

Flow injection analysis with electrochemical detection for rapid identification of platinum-based cytostatics and platinum chlorides in water.

scientific article

Fluorescence resonance energy transfer between green fluorescent protein and doxorubicin enabled by DNA nanotechnology

scientific article published on 13 October 2014

Folic acid-mediated re-shuttling of ferritin receptor specificity towards a selective delivery of highly cytotoxic nickel(II) coordination compounds

scientific article published on 31 December 2018

From solid state to in vitro anticancer activity of copper(II) compounds with electronically-modulated NNO Schiff base ligands

scientific article published on 15 October 2020

Fully automated two-step assay for detection of metallothionein through magnetic isolation using functionalized γ-Fe2O3 particles.

scientific article

Functional Analysis of Novicidin Peptide: Coordinated Delivery System for Zinc via Schiff Base Ligand

scientific article published on 22 August 2018

Guidelines for Homology Modeling of Dopamine, Norepinephrine, and Serotonin Transporters

scientific article

Identification of Sarcosine as a Target Molecule for the Canine Olfactory Detection of Prostate Carcinoma.

scientific article published on 21 March 2018

Identification of estrogen receptor proteins in breast cancer cells using matrix-assisted laser desorption/ionization time of flight mass spectrometry (Review).

scientific article

Improving cytocompatibility of CdTe quantum dots by Schiff-base-coordinated lanthanides surface doping.

scientific article published on 19 April 2018

In vitro interactions between 17β-estradiol and DNA result in formation of the hormone-DNA complexes.

scientific article

Influence of Long-Distance Bicycle Riding on Serum/Urinary Biomarkers of Prostate Cancer.

scientific article published on 17 March 2016

Influence of microbiome species in hard-to-heal wounds on disease severity and treatment duration

scientific article published on 27 October 2015

Label-free bead-based metallothionein electrochemical immunosensor.

scientific article published on 29 May 2015

MALDI MSI of MeLiM melanoma: Searching for differences in protein profiles

scientific article published on 8 December 2017

Magnetic Nanoparticles: From Design and Synthesis to Real World Applications.

scientific article published on 29 August 2017

Mass spectrometric imaging of cysteine rich proteins in human skin

scientific article published on 02 December 2018

Metallothionein as a Scavenger of Free Radicals - New Cardioprotective Therapeutic Agent or Initiator of Tumor Chemoresistance?

scientific article published on October 2015

Metallothioneins in Prion- and Amyloid-Related Diseases

scientific article published on 20 February 2016

Microfluidic chip coupled with modified paramagnetic particles for sarcosine isolation in urine

scientific article published in September 2013

Nanoparticle-drug conjugates treating bacterial infections

scientific article published on 19 June 2019

Nanoparticles Suitable for BCAA Isolation Can Serve for Use in Magnetic Lipoplex-Based Delivery System for L, I, V, or R-rich Antimicrobial Peptides

scientific article published on 31 March 2016

Nanotechnologies in protein microarrays.

scientific article published on 21 May 2015

Norepinephrine transporter-derived homing peptides enable rapid endocytosis of drug delivery nanovehicles into neuroblastoma cells

scientific article published on 13 July 2020

Novel vancomycin-peptide conjugate as potent antibacterial agent against vancomycin-resistant

scientific article published on 12 October 2018

Paramagnetic nanoparticles as a platform for FRET-based sarcosine picomolar detection

scientific article

Passive Diffusion vs Active pH-Dependent Encapsulation of Tyrosine Kinase Inhibitors Vandetanib and Lenvatinib into Folate-Targeted Ferritin Delivery System

scientific article published on 06 January 2021

Perspective of Use of Antiviral Peptides against Influenza Virus

scientific article

Post-treatment urinary sarcosine as a predictor of recurrent relapses in patients with prostate cancer

scientific article published on 12 September 2018

Preconcentration based on paramagnetic microparticles for the separation of sarcosine using hydrophilic interaction liquid chromatography coupled with coulometric detection

scientific article published on 29 January 2014

Prostate tumor attenuation in the nu/nu murine model due to anti-sarcosine antibodies in folate-targeted liposomes

scientific article published on 20 September 2016

Prostate-Specific Membrane Antigen-Targeted Site-Directed Antibody-Conjugated Apoferritin Nanovehicle Favorably Influences In Vivo Side Effects of Doxorubicin.

scientific article

Proteomic Signature of Neuroblastoma Cells UKF-NB-4 Reveals Key Role of Lysosomal Sequestration and the Proteasome Complex in Acquiring Chemoresistance to Cisplatin

scientific article published on 11 January 2019

Relation of exposure to amino acids involved in sarcosine metabolic pathway on behavior of non-tumor and malignant prostatic cell lines

scientific article published on 5 February 2016

Retracted: Sarcosine Up-Regulates Expression of Genes Involved in Cell Cycle Progression of Metastatic Models of Prostate Cancer

retracted article

Sarcosine as a potential prostate cancer biomarker--a review

scientific article published on 04 July 2013

Sarcosine influences apoptosis and growth of prostate cells via cell-type specific regulation of distinct sets of genes.

scientific article

Site-Directed Conjugation of Antibodies to Apoferritin Nanocarrier for Targeted Drug Delivery to Prostate Cancer Cells

scientific article published on 02 June 2016

Size-related cytotoxicological aspects of polyvinylpyrrolidone-capped platinum nanoparticles.

scientific article

Spatial mapping of metals in tissue-sections using combination of mass-spectrometry and histology through image registration

scientific article published on 10 January 2017

Structural effects and nanoparticle size are essential for quantum dots-metallothionein complex formation

scientific article published on 26 June 2015

Study of linkage between glutathione pathway and the antibiotic resistance of Escherichia coli from patients' swabs.

scientific article published on 31 March 2015

Synthesis and structural characterization of antimicrobial binuclear copper(II) coordination compounds bridged by hydroxy- and/or thiodipropionic acid

scientific article published on 06 November 2018

Targeting Neuroblastoma Cell Surface Proteins: Recommendations for Homology Modeling of hNET, ALK, and TrkB

scientific article (publication date: 2017)

Ten quick tips for homology modeling of high-resolution protein 3D structures

scientific article published on 02 April 2020

The Zinc-Schiff Base-Novicidin Complex as a Potential Prostate Cancer Therapy

scientific article

Transcriptomic Landscape of Cisplatin-Resistant Neuroblastoma Cells

scientific article published on 12 March 2019

Transport phenomena of nanoparticles in plants and animals/humans.

scientific article

Trk Receptors and Neurotrophin Cross-Interactions: New Perspectives Toward Manipulating Therapeutic Side-Effects

scientific article published on 3 May 2017

Tuning the surface coating of IONs toward efficient sonochemical tethering and sustained liberation of topoisomerase II poisons

scientific article published on 17 September 2019

Visualization of stable ferritin complexes with palladium, rhodium and iridium nanoparticles detected by their catalytic activity in native polyacrylamide gels

scientific article published on 3 October 2017

Zinc and zinc-containing biomolecules in childhood brain tumors.

scientific article published on 16 September 2016

γ-Fe2O3 Nanoparticles Covered with Glutathione-Modified Quantum Dots as a Fluorescent Nanotransporter

article published in 2014