List of works - Sarah A Head

Antifungal drug itraconazole targets VDAC1 to modulate the AMPK/mTOR signaling axis in endothelial cells

scientific article

Astemizole Inhibits mTOR Signaling and Angiogenesis by Blocking Cholesterol Trafficking

scientific article published on 23 June 2018

Divergence of Antiangiogenic Activity and Hepatotoxicity of Different Stereoisomers of Itraconazole.

scientific article published on 22 January 2016

Identification of Small Molecule-binding Proteins in a Native Cellular Environment by Live-cell Photoaffinity Labeling

scientific article published on 20 September 2016

Inhibition of angiogenesis by selective estrogen receptor modulators through blockade of cholesterol trafficking rather than estrogen receptor antagonism

scientific article published on 20 March 2015

Insights into the structure-activity relationship of the anticancer compound ZJ-101, a derivative of marine natural product superstolide A: A critical role played by the conjugated trienyl lactone moiety.

scientific article published on 22 June 2016

Insights into the structure-activity relationship of the anticancer compound ZJ-101, a derivative of marine natural product superstolide A: A role played by the lactone moiety

scientific article published on 20 August 2016

Insights into the structure-activity relationship of the anticancer compound ZJ-101: A critical role played by the cyclohexene ring

scientific article published on 19 April 2016

Itraconazole Side Chain Analogues: Structure–Activity Relationship Studies for Inhibition of Endothelial Cell Proliferation, Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) Glycosylation, and Hedgehog Signaling ⬇️

scientific article published on October 5, 2011

Itraconazole inhibits enterovirus replication by targeting the oxysterol-binding protein

scientific article

Mechanistic insights into the activation of oncogenic forms of EGF receptor ⬇️

scientific article published on November 20, 2011

Pharmacological blockade of cholesterol trafficking by cepharanthine in endothelial cells suppresses angiogenesis and tumor growth.

scientific article published on 15 September 2017

Silencing of SRRM4 suppresses microexon inclusion and promotes tumor growth across cancers

scientific article published on 23 February 2021

Simultaneous Targeting of NPC1 and VDAC1 by Itraconazole Leads to Synergistic Inhibition of mTOR Signaling and Angiogenesis.

scientific article published on 2 December 2016

Structure-activity relationship study of itraconazole, a broad-range inhibitor of picornavirus replication that targets oxysterol-binding protein (OSBP)

scientific article published on 26 May 2018

Targeted Delivery and Sustained Antitumor Activity of Triptolide through Glucose Conjugation

scientific article published on 30 August 2016

List of works by Sarah A Head