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List of works by Osamu Wada-Hiraike

A Potential Role for Endoplasmic Reticulum Stress in Progesterone Deficiency in Obese Women

scientific article published on 25 November 2016

A coexistence case of right tubal adenomyoma and ectopic pregnancy

scientific article published on 27 May 2014

A nationwide survey on gynecologic endoscopic surgery in Japan, 2014-2016

scientific article published on 20 August 2018

A potential role of endoplasmic reticulum stress in development of ovarian hyperstimulation syndrome

scientific article published on 28 March 2016

A survey of public attitudes toward uterus transplantation, surrogacy, and adoption in Japan

scientific article published on 30 October 2019

A survey of public attitudes towards third-party reproduction in Japan in 2014

scientific article published in PLoS ONE

Aberrant implantation and growth of uterine leiomyoma in the abdominal wall after laparoscopically assisted myomectomy

scientific article published on 17 September 2009

Accumulation of advanced glycation end products in follicles is associated with poor oocyte developmental competence

scientific article published on 01 November 2019

Activation of Endoplasmic Reticulum Stress in Granulosa Cells from Patients with Polycystic Ovary Syndrome Contributes to Ovarian Fibrosis.

scientific article published on 7 September 2017

Activation of Nrf2 might reduce oxidative stress in human granulosa cells

scientific article

Activation of Nrf2/Keap1 pathway by oral Dimethylfumarate administration alleviates oxidative stress and age-associated infertility might be delayed in the mouse ovary

article

Activation of endoplasmic reticulum stress mediates oxidative stress-induced apoptosis of granulosa cells in ovaries affected by endometrioma

scientific article published on 01 January 2020

Alternative strategies to in vitro fertilization/intracytoplasmic sperm injection treatment for aged infertile women.

scientific article published on 13 August 2011

Analysis of the status of the novel estrogen receptor α (ERα) coactivator p72 in endometrial cancer and its cross talk with erbB-2 in the transactivation of ERα

scientific article published on May 1, 2008

Androgens Increase Accumulation of Advanced Glycation End Products in Granulosa Cells by Activating ER Stress in PCOS

scientific article published on 01 February 2020

Anti-tumor activity of olaparib, a poly (ADP-ribose) polymerase (PARP) inhibitor, in cultured endometrial carcinoma cells

scientific article

Antitumor activity and induction of TP53-dependent apoptosis toward ovarian clear cell adenocarcinoma by the dual PI3K/mTOR inhibitor DS-7423.

scientific article published on 04 February 2014

Antitumor activity of a combination of dual PI3K/mTOR inhibitor SAR245409 and selective MEK1/2 inhibitor pimasertib in endometrial carcinomas.

scientific article published on 29 May 2015

Assisted reproductive technology pregnancy complications are significantly associated with endometriosis severity before conception: a retrospective cohort study.

scientific article

Autophagy inhibition augments resveratrol-induced apoptosis in Ishikawa endometrial cancer cells.

scientific article published on 08 August 2016

CCAR2 negatively regulates nuclear receptor LXRα by competing with SIRT1 deacetylase

scientific article

Cancer-associated fibroblast suppresses killing activity of natural killer cells through downregulation of poliovirus receptor (PVR/CD155), a ligand of activating NK receptor

scientific article published on 26 July 2016

Cellular mechanisms of growth inhibition of human endometrial cancer cell line by an antagonist of growth hormone-releasing hormone

scientific article

Cellular mechanisms of growth inhibition of human epithelial ovarian cancer cell line by LH-releasing hormone antagonist Cetrorelix

scientific article published on August 2002

Characterization of TP53 and PI3K signaling pathways as molecular targets in gynecologic malignancies

scientific article published on 20 April 2016

Clinical aspects and management of inguinal endometriosis: A case series of 20 patients

scientific article published on 05 August 2019

Clinical significance of Gremlin 1 in cervical cancer and its effects on cancer stem cell maintenance.

scientific article published on 30 October 2015

Concomitant ovarian drilling and oocyte retrieval by laparoendoscopic single-site surgery led to live birth using in vitro maturation of oocyte and transfer of frozen-thawed blastocyst in woman with polycystic ovary syndrome

scientific article published in May 2014

Contralateral ovarian endometrioma recurrence after unilateral salpingo-oophorectomy

scientific article published on 02 May 2019

Correction: Integrated Copy Number and Expression Analysis Identifies Profiles of Whole-Arm Chromosomal Alterations and Subgroups with Favorable Outcome in Ovarian Clear Cell Carcinomas

scientific article published on 6 July 2015

Cross-Talk between Fas/Fas ligand system and nitric oxide in the pathway subserving granulosa cell apoptosis: a possible regulatory mechanism for ovarian follicle atresia

scientific article published on 4 November 2004

Decreased expression of the plasminogen activator inhibitor type 1 is involved in degradation of extracellular matrix surrounding cervical cancer stem cells.

scientific article published on 9 December 2015

Development of ovarian cancer after excision of endometrioma.

scientific article published on 17 August 2016

Diameter of dominant leiomyoma is a possible determinant to predict coexistent endometriosis.

scientific article published on 27 February 2012

Dienogest suppresses cellular proliferation status of endometrial polyps and acts differently depending on the morphological type

scientific article published on 01 January 2020

Distribution of the follicular and luteal phase lengths and their age‐dependent changes in Japanese women: A large population study

scientific article published in 2023

Drospirenone reduces inflammatory cytokines, vascular endothelial growth factor (VEGF) and nerve growth factor (NGF) expression in human endometriotic stromal cells

scientific article published on 29 December 2016

Effects of 1,25-Dihydroxy Vitamin D3 on Endometriosis.

scientific article published in April 2016

Endometriosis Triggers Excessive Activation of Primordial Follicles via PI3K-PTEN-Akt-Foxo3 Pathway

scientific article published on 01 November 2019

Endoplasmic Reticulum Stress Activated by Androgen Enhances Apoptosis of Granulosa Cells via Induction of Death Receptor 5 in PCOS

scientific article published on 01 January 2019

Expression of ALDH1A Isozymes in Human Endometrium with and without Endometriosis and in Ovarian Endometrioma

scientific article published on 01 January 2020

Expression of DBC1 is associated with nuclear grade and HER2 expression in breast cancer.

scientific article

Expression of Nerve Injury-Induced Protein1 (Ninj1) in Endometriosis

article

Factors that predict poor clinical course among patients hospitalized with pelvic inflammatory disease

scientific article

Four Cases of Postoperative Pneumothorax Among 2814 Consecutive Laparoscopic Gynecologic Surgeries: A Possible Correlation Between Postoperative Pneumothorax and Endometriosis.

scientific article published on 30 April 2015

Genome-wide single nucleotide polymorphism arrays as a diagnostic tool in patients with synchronous endometrial and ovarian cancer.

scientific article

Genotype-dependent efficacy of a dual PI3K/mTOR inhibitor, NVP-BEZ235, and an mTOR inhibitor, RAD001, in endometrial carcinomas

scientific article

Guideline for cryopreservation of unfertilized eggs and ovarian tissues in Japan Society of Reproductive Medicine: Ethics Committee in Japan Society of Reproductive Medicine.

scientific article published on 23 October 2018

HAND2-mediated proteolysis negatively regulates the function of estrogen receptor α.

scientific article published on 9 July 2015

HPV-16 impairs the subcellular distribution and levels of expression of protein phosphatase 1γ in cervical malignancy

scientific article

Human chorionic gonadotropin combined with progesterone for luteal support improves pregnancy rate in patients with low late-midluteal estradiol levels in IVF cycles

scientific article

IFITM1 is a Novel, Highly Sensitive Marker for Endometriotic Stromal Cells in Ovarian and Extragenital Endometriosis

scientific article published on 21 February 2019

IFITM1 is a Novel, Highly Sensitive Marker for Endometriotic Stromal Cells in Ovarian and Extragenital Endometriosis

scientific article published on 20 May 2020

Identification of DBC1 as a transcriptional repressor for BRCA1

scientific article

Identifying patients who can improve fertility with myomectomy.

scientific article published on 2 December 2014

Increased tissue levels of omega-3 polyunsaturated fatty acids prevents pathological preterm birth

scientific article

Inhibition of endoplasmic reticulum (ER) stress sensors sensitizes cancer stem-like cells to ER stress-mediated apoptosis

scientific article published on 17 June 2016

Integrated copy number and expression analysis identifies profiles of whole-arm chromosomal alterations and subgroups with favorable outcome in ovarian clear cell carcinomas

scientific article published on 4 June 2015

Intracellular signaling entropy can be a biomarker for predicting the development of cervical intraepithelial neoplasia

scientific article

Intraperitoneal neutrophils activated by KRAS-induced ovarian cancer exert antitumor effects by modulating adaptive immunity

scientific article published on 26 July 2018

Laparoscopic ovarian-sparing surgery for a young woman with an exophytic ovarian fibroma.

scientific article published on 22 July 2013

Long-term dienogest administration in patients with symptomatic adenomyosis

scientific article published on 29 May 2018

Low uptake of fluorodeoxyglucose in positron emission tomography/computed tomography in ovarian clear cell carcinoma may reflect glutaminolysis of its cancer stem cell-like properties.

scientific article published on 20 January 2017

MDM2 is a potential therapeutic target and prognostic factor for ovarian clear cell carcinomas with wild type TP53.

scientific article published on 21 September 2016

Matrix metalloproteinase (MMP)-9 in cancer-associated fibroblasts (CAFs) is suppressed by omega-3 polyunsaturated fatty acids in vitro and in vivo

scientific article

Mdm2-p53-SF1 pathway in ovarian granulosa cells directs ovulation and fertilization by conditioning oocyte quality

scientific article published on 27 September 2018

Modification of the Tumor Microenvironment in KRAS or c-MYC-Induced Ovarian Cancer-Associated Peritonitis

scientific article

Multifunctional transcription factor TFII-I is an activator of BRCA1 function

scientific article

Neutrophil depletion reduces endometriotic lesion formation in mice.

scientific article published on 19 July 2016

New developments in oestrogen signalling in colonic epithelium

scientific article published on 01 December 2006

Oncogenic histone methyltransferase EZH2: A novel prognostic marker with therapeutic potential in endometrial cancer

scientific article published on 17 March 2017

Oral vaccination against HPV E7 for treatment of cervical intraepithelial neoplasia grade 3 (CIN3) elicits E7-specific mucosal immunity in the cervix of CIN3 patients

scientific article published on 22 September 2014

PAX8: A Highly Sensitive Marker for the Glands in Extragenital Endometriosis

scientific article published on 14 February 2019

PAX8: A Highly Sensitive Marker for the Glands in Extragenital Endometriosis

scientific article published on 19 May 2020

PI3K/mTOR pathway inhibition overcomes radioresistance via suppression of the HIF1-α/VEGF pathway in endometrial cancer.

scientific article published on 22 April 2015

Prediction of the operative time for hysteroscopic myomectomy for leiomyomas penetrating the intramural cavity using leiomyoma weight and clinical characteristics of patients

scientific article published on 30 September 2018

Preoperative assessment of factors associated with difficulty in performing total laparoscopic hysterectomy.

scientific article

Prognostic importance of CDK4/6-specific activity as a predictive marker for recurrence in patients with endometrial cancer, with or without adjuvant chemotherapy

scientific article published on 10 November 2015

Putative tumor suppression function of SIRT6 in endometrial cancer

scientific article published on 13 July 2015

Regeneration of cervical reserve cell-like cells from human induced pluripotent stem cells (iPSCs): A new approach to finding targets for cervical cancer stem cell treatment.

scientific article published on 3 April 2017

Regulation of SIRT1 determines initial step of endometrial receptivity by controlling E-cadherin expression

scientific article

Relationship between tartrate-resistant acid phosphatase 5b and stress fractures in female athletes

scientific article published on 15 June 2020

Repression of estrogen receptor beta function by putative tumor suppressor DBC1

scientific article

Resveratrol Enhances Apoptosis in Endometriotic Stromal Cells.

scientific article published on 19 January 2016

Resveratrol Protects Against Pathological Preterm Birth by Suppression of Macrophage-Mediated Inflammation.

scientific article published on 2 June 2015

Resveratrol promotes expression of SIRT1 and StAR in rat ovarian granulosa cells: an implicative role of SIRT1 in the ovary.

scientific article

Resveratrol suppresses inflammatory responses in endometrial stromal cells derived from endometriosis: a possible role of the sirtuin 1 pathway.

scientific article published on 10 December 2013

Role of estrogen receptor beta in colonic epithelium

scholarly article

Role of multifunctional transcription factor TFII-I and putative tumour suppressor DBC1 in cell cycle and DNA double strand damage repair.

scientific article

Role of oxidative stress in follicular fluid on embryos of patients undergoing assisted reproductive technology treatment

scientific article published on 01 July 2019

SIRT3 positively regulates the expression of folliculogenesis- and luteinization-related genes and progesterone secretion by manipulating oxidative stress in human luteinized granulosa cells.

scientific article

STAT3 activity regulates sensitivity to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in cervical cancer cells.

scientific article published on 06 September 2016

Sequential effects of the proteasome inhibitor bortezomib and chemotherapeutic agents in uterine cervical cancer cell lines

scientific article published on 5 October 2012

Sessile polyps and pedunculated polyps respond differently to oral contraceptives

scientific article published on 09 June 2010

Significance of survivin as a prognostic factor and a therapeutic target in endometrial cancer.

scientific article published on 11 April 2016

Simultaneous Detection and Evaluation of Four Subsets of CD4+ T Lymphocyte in Lesions and Peripheral Blood in Endometriosis

scientific article published on 20 September 2015

Spheroid cancer stem cells display reprogrammed metabolism and obtain energy by actively running the tricarboxylic acid (TCA) cycle

scientific article published on 23 April 2016

Spontaneous cessation and recurrence of massive uterine bleeding can occur in uterine artery pseudoaneurysm after laparoscopically assisted myomectomy

scientific article published on 25 September 2012

Synergistic antitumor effects of combination PI3K/mTOR and MEK inhibition (SAR245409 and pimasertib) in mucinous ovarian carcinoma cells by fluorescence resonance energy transfer imaging

scientific article published on 18 April 2016

Systemic delivery of siRNA by actively targeted polyion complex micelles for silencing the E6 and E7 human papillomavirus oncogenes

scientific article published on 12 March 2016

Targeting glutamine metabolism and the focal adhesion kinase additively inhibits the mammalian target of the rapamycin pathway in spheroid cancer stem-like properties of ovarian clear cell carcinoma in vitro.

scientific article published on 23 February 2017

Temporary balloon occlusion of the uterine arteries to control hemorrhage during hysterectomy in a case of uterine arteriovenous fistula

scientific article published on 17 September 2014

The DNA mismatch repair gene hMSH2 is a potent coactivator of oestrogen receptor alpha

scientific article published on June 2005

The Emerging Role of FOXL2 in Regulating the Transcriptional Activation Function of Estrogen Receptor β: An Insight Into Ovarian Folliculogenesis.

scientific article published in June 2016

The anti-malarial chloroquine suppresses proliferation and overcomes cisplatin resistance of endometrial cancer cells via autophagy inhibition.

scientific article

The assessment of myometrium perfusion in patients with uterine fibroid by arterial spin labeling MRI.

scientific article

The effects of tokishakuyakusan, a traditional Japanese medicine (kampo), ferulic acid and paeoniflorin, on human endometriotic stromal cells and peritoneal macrophages

scientific article published on 21 February 2020

The efficacy of non-assisted reproductive technology treatment might be limited in infertile patients with advanced endometriosis in their 30s

article

The impact of elevated thyroid stimulating hormone on female subfertility

scientific article published on 13 August 2015

The prevalence of cervical regulatory T cells in HPV-related cervical intraepithelial neoplasia (CIN) correlates inversely with spontaneous regression of CIN.

scientific article

Thoracic endometriosis syndrome: Comparison between catamenial pneumothorax or endometriosis-related pneumothorax and catamenial hemoptysis

scientific article published on 20 April 2018

Use of selective PGE2 receptor antagonists on human endometriotic stromal cells and peritoneal macrophages

scientific article published on 03 December 2020

Usefulness of T2 star-weighted imaging in ovarian cysts and tumors

scientific article published on 30 June 2016

Uterine arteriovenous fistula treated with repetitive transcatheter embolization: case report

scientific article published on 01 November 2012

Uterine artery pseudoaneurysm after cesarean section: case report and literature review.

scientific article published on 24 July 2010

Vaginal Stenosis After Gonadotropin-Releasing Hormone Agonist Therapy During Treatment for Acute Lymphoblastic Leukemia

scientific article published on 01 April 2016

Vaginal cancer possibly caused by pessary and immunocompromised condition: Multiple risk factors may influence vaginal cancer development.

scientific article