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List of works by Joakim E. Swedberg

Calcium-Mediated Allostery of the EGF Fold

scientific article published on 09 May 2018

Conformational Flexibility Is a Determinant of Permeability for Cyclosporin.

scientific article published on 5 February 2018

Cyclic alpha-conotoxin peptidomimetic chimeras as potent GLP-1R agonists

scientific article published on 29 August 2015

Cyclotides as a basis for drug design

scientific article published on 21 February 2012

Design and synthesis of truncated EGF-A peptides that restore LDL-R recycling in the presence of PCSK9 in vitro

scientific article

Design of Potent and Selective Cathepsin G Inhibitors Based on the Sunflower Trypsin Inhibitor-1 Scaffold

scientific article

Direct and indirect mechanisms of KLK4 inhibition revealed by structure and dynamics

scientific article

Disulfide-rich macrocyclic peptides as templates in drug design

scientific article published on 06 March 2014

Diverse cyclic seed peptides in the Mexican zinnia (Zinnia haageana).

scientific article

Effects of Cyclization on Peptide Backbone Dynamics.

scientific article

Effects of linker sequence modifications on the structure, stability, and biological activity of a cyclic α-conotoxin

scientific article published on 01 November 2016

Engineered protease inhibitors based on sunflower trypsin inhibitor-1 (SFTI-1) provide insights into the role of sequence and conformation in Laskowski mechanism inhibition.

scientific article published on 18 May 2015

Exploring experimental and computational markers of cyclic peptides: Charting islands of permeability

scientific article published on 25 April 2015

Exploring the active site binding specificity of kallikrein-related peptidase 5 (KLK5) guides the design of new peptide substrates and inhibitors

scientific article published on 19 February 2016

Highly Potent and Selective Plasmin Inhibitors Based on the Sunflower Trypsin Inhibitor-1 Scaffold Attenuate Fibrinolysis in Plasma

scientific article published on 26 December 2018

Improving the Selectivity of Engineered Protease Inhibitors: Optimizing the P2 Prime Residue Using a Versatile Cyclic Peptide Library

scientific article published on 22 September 2015

Mastering the canonical loop of serine protease inhibitors: enhancing potency by optimising the internal hydrogen bond network

scientific article (publication date: 27 April 2011)

Mechanism-based selection of a potent kallikrein-related peptidase 7 inhibitor from a versatile library based on the sunflower trypsin inhibitor SFTI-1

scientific article published on 01 September 2013

Natural and engineered plasmin inhibitors: applications and design strategies.

scientific article published on 11 January 2012

Non-combinatorial library screening reveals subsite cooperativity and identifies new high-efficiency substrates for kallikrein-related peptidase 14.

scientific article

Paclitaxel resistance and multicellular spheroid formation are induced by kallikrein-related peptidase 4 in serous ovarian cancer cells in an ascites mimicking microenvironment

scientific article

Plasmin substrate binding site cooperativity guides the design of potent peptide aldehyde inhibitors.

scientific article

Potent, Selective, and Cell-Penetrating Inhibitors of Kallikrein-Related Peptidase 4 Based on the Cyclic Peptide MCoTI-II

scientific article published on 21 November 2018

Rapid and Scalable Plant-Based Production of a Potent Plasmin Inhibitor Peptide

scientific article published on 15 May 2019

Recent Progress Towards Pharmaceutical Applications of Disulfide-Rich Cyclic Peptides ⬇️

scientific article published on September 1, 2013

Selective Substrates and Inhibitors for Kallikrein-Related Peptidase 7 (KLK7) Shed Light on KLK Proteolytic Activity in the Stratum Corneum

scientific article published on 30 September 2016

Selective cleavage of human sex hormone-binding globulin by kallikrein-related peptidases and effects on androgen action in LNCaP prostate cancer cells

scientific article published on 30 April 2012

Structural and functional characterization of chimeric cyclotides from the Möbius and trypsin inhibitor subfamilies

scientific article published on 3 August 2016

Substrate-Guided Design of Selective FXIIa Inhibitors Based on the Plant-Derived Momordica cochinchinensis Trypsin Inhibitor-II (MCoTI-II) Scaffold

scientific article published on 19 July 2016

Substrate-guided design of a potent and selective kallikrein-related peptidase inhibitor for kallikrein 4.

scientific article

The evolution of Momordica cyclic peptides

scientific article

The temperature activated HtrA protease from pathogen Chlamydia trachomatis acts as both a chaperone and protease at 37 degrees C.

scientific article published on 26 June 2007

Translational diffusion of cyclic peptides measured using pulsed-field gradient NMR.

scientific article published on 15 September 2014

Truncated Glucagon-like Peptide-1 and Exendin-4 α-Conotoxin pl14a Peptide Chimeras Maintain Potency and α-Helicity and Reveal Interactions Vital for cAMP Signaling in Vitro.

scientific article published on 10 May 2016

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