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List of works by Simon J de Veer

A new TRPV3 missense mutation in a patient with Olmsted syndrome and erythromelalgia

scientific article published on March 2014

Amino Acid Scanning at P5' within the Bowman-Birk Inhibitory Loop Reveals Specificity Trends for Diverse Serine Proteases

scientific article published on 29 March 2019

Attenuated kallikrein-related peptidase activity disrupts desquamation and leads to stratum corneum thickening in human skin equivalent models

scientific article published on 21 July 2016

Binding Loop Substitutions in the Cyclic Peptide SFTI-1 Generate Potent and Selective Chymase Inhibitors

scientific article published on 09 January 2020

Characterising the Subsite Specificity of Urokinase-Type Plasminogen Activator and Tissue-Type Plasminogen Activator using a Sequence-Defined Peptide Aldehyde Library

scientific article published on 24 October 2018

Cyclotides as Tools in Chemical Biology.

scientific article published on 23 June 2017

Cyclotides: From Structure to Function

scientific article published on 12 December 2019

Design of Potent and Selective Cathepsin G Inhibitors Based on the Sunflower Trypsin Inhibitor-1 Scaffold

scientific article

Direct and indirect mechanisms of KLK4 inhibition revealed by structure and dynamics

scientific article

Engineered protease inhibitors based on sunflower trypsin inhibitor-1 (SFTI-1) provide insights into the role of sequence and conformation in Laskowski mechanism inhibition.

scientific article published on 18 May 2015

Engineering potent mesotrypsin inhibitors based on the plant-derived cyclic peptide, sunflower trypsin inhibitor-1

scientific article published on 21 June 2018

Exploring the active site binding specificity of kallikrein-related peptidase 5 (KLK5) guides the design of new peptide substrates and inhibitors

scientific article published on 19 February 2016

Improving the Selectivity of Engineered Protease Inhibitors: Optimizing the P2 Prime Residue Using a Versatile Cyclic Peptide Library

scientific article published on 22 September 2015

Iterative Optimization of the Cyclic Peptide SFTI-1 Yields Potent Inhibitors of Neutrophil Proteinase 3

scientific article published on 19 July 2019

KLK4 Inhibition by Cyclic and Acyclic Peptides: Structural and Dynamical Insights into Standard-Mechanism Protease Inhibitors

scientific article published on 13 May 2019

Kallikrein-Related Peptidase 5 Contributes to H3N2 Influenza Virus Infection in Human Lungs

scientific article published on 14 June 2017

Mastering the canonical loop of serine protease inhibitors: enhancing potency by optimising the internal hydrogen bond network

scientific article (publication date: 27 April 2011)

Mechanism-based selection of a potent kallikrein-related peptidase 7 inhibitor from a versatile library based on the sunflower trypsin inhibitor SFTI-1

scientific article published on 01 September 2013

Non-combinatorial library screening reveals subsite cooperativity and identifies new high-efficiency substrates for kallikrein-related peptidase 14.

scientific article

Olmsted syndrome with erythromelalgia caused by recessive transient receptor potential vanilloid 3 mutations

scientific article published on 04 August 2014

Potent, Selective, and Cell-Penetrating Inhibitors of Kallikrein-Related Peptidase 4 Based on the Cyclic Peptide MCoTI-II

scientific article published on 21 November 2018

Potent, multi-target serine protease inhibition achieved by a simplified β-sheet motif

scientific article published in PLoS ONE

Proteases and proteomics: cutting to the core of human skin pathologies

scientific article published on 13 April 2014

Proteases: common culprits in human skin disorders

scientific article published on 28 December 2013

Selective Substrates and Inhibitors for Kallikrein-Related Peptidase 7 (KLK7) Shed Light on KLK Proteolytic Activity in the Stratum Corneum

scientific article published on 30 September 2016

Selective cleavage of human sex hormone-binding globulin by kallikrein-related peptidases and effects on androgen action in LNCaP prostate cancer cells

scientific article published on 30 April 2012

Substrate-Guided Design of Selective FXIIa Inhibitors Based on the Plant-Derived Momordica cochinchinensis Trypsin Inhibitor-II (MCoTI-II) Scaffold

scientific article published on 19 July 2016

Substrate-guided design of a potent and selective kallikrein-related peptidase inhibitor for kallikrein 4.

scientific article

Transgenic kallikrein 5 mice reproduce major cutaneous and systemic hallmarks of Netherton syndrome.

scientific article published on 17 February 2014

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