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List of works by Luke Norton

Basal and insulin-stimulated pyruvate dehydrogenase complex activation, glycogen synthesis and metabolic gene expression in human skeletal muscle the day after a single bout of exercise.

scientific article published on 9 April 2010

Calpain-10 gene and protein expression in human skeletal muscle: effect of acute lipid-induced insulin resistance and type 2 diabetes

scientific article published on 18 December 2007

Characterization of GLUT4 and calpain expression in healthy human skeletal muscle during fasting and refeeding.

scientific article published in March 2007

Chromatin occupancy of transcription factor 7-like 2 (TCF7L2) and its role in hepatic glucose metabolism ⬇️

scientific article published on September 7, 2011

Dapagliflozin Enhances Fat Oxidation and Ketone Production in Patients With Type 2 Diabetes

scientific article published on 25 August 2016

Dapagliflozin improves muscle insulin sensitivity but enhances endogenous glucose production.

scientific article published on 27 January 2014

Distinct β-Cell Defects in Impaired Fasting Glucose and Impaired Glucose Tolerance ⬇️

scientific article published on February 1, 2012

Effect of Chronic Hyperglycemia on Glucose Metabolism in Subjects With Normal Glucose Tolerance

scientific article published on 13 September 2018

Effect of exercise and insulin on SREBP-1c expression in human skeletal muscle: potential roles for the ERK1/2 and Akt signalling pathways

scientific article published in November 2007

Efficacy and Safety of SGLT2 Inhibitors in the Treatment of Type 2 Diabetes Mellitus ⬇️

scientific article published on June 1, 2012

Elevated Free Fatty Acids Attenuate the Insulin-Induced Suppression of PDK4 Gene Expression in Human Skeletal Muscle: Potential Role of Intramuscular Long-Chain Acyl-Coenzyme A

article

Empagliflozin and Kinetics of Renal Glucose Transport in Healthy Individuals and Individuals With Type 2 Diabetes.

scientific article published on 20 April 2017

Exercise under hyperinsulinaemic conditions increases whole-body glucose disposal without affecting muscle glycogen utilisation in type 1 diabetes

scientific article published on 21 November 2006

FGF21 Is an Insulin-Dependent Postprandial Hormone in Adult Humans.

scientific article

High-Fat/Low-Carbohydrate Diet Reduces Insulin-Stimulated Carbohydrate Oxidation but Stimulates Nonoxidative Glucose Disposal in Humans: An Important Role for Skeletal Muscle Pyruvate Dehydrogenase Kinase 4

scientific article published on 24 October 2006

Hyperinsulinaemia during exercise does not suppress hepatic glycogen concentrations in patients with type 1 diabetes: a magnetic resonance spectroscopy study.

scientific article published on 18 July 2007

Impaired early- but not late-phase insulin secretion in subjects with impaired fasting glucose

scientific article published on 8 May 2011

Increased lipid availability for three days reduces whole body glucose uptake, impairs muscle mitochondrial function and initiates opposing effects on PGC-1α promoter methylation in healthy subjects

scientific article published on 20 December 2017

Independent and combined effects of acute physiological hyperglycaemia and hyperinsulinaemia on metabolic gene expression in human skeletal muscle

article

Lentivirus shRNA Grb10 targeting the pancreas induces apoptosis and improved glucose tolerance due to decreased plasma glucagon levels

scientific article

Linkage of type 2 diabetes on chromosome 9p24 in Mexican Americans: additional evidence from the Veterans Administration Genetic Epidemiology Study (VAGES).

scientific article published on 21 September 2013

Mitochondrial pyruvate and fatty acid flux modulate MICU1-dependent control of MCU activity

scientific article published on 21 April 2020

Novel hypothesis to explain why SGLT2 inhibitors inhibit only 30-50% of filtered glucose load in humans

scientific article

Revitalization of pioglitazone: the optimum agent to be combined with a sodium-glucose co-transporter-2 inhibitor.

scientific article published on 25 February 2016

Role of sodium-glucose cotransporter 2 (SGLT 2) inhibitors in the treatment of type 2 diabetes.

scientific article published on 23 May 2011

Skeletal muscle fatty acid transporter protein expression in type 2 diabetes patients compared with overweight, sedentary men and age-matched, endurance-trained cyclists

scientific article published on 30 March 2007

Sodium-glucose co-transporter (SGLT) and glucose transporter (GLUT) expression in the kidney of type 2 diabetic subjects.

scientific article published on 6 May 2017

The Diabetes Gene and Wnt Pathway Effector TCF7L2 Regulates Adipocyte Development and Function.

scientific article published on 9 January 2018

The mechanisms of genome-wide target gene regulation by TCF7L2 in liver cells

scientific article

The relationship between {beta}-cell function and glycated hemoglobin: results from the veterans administration genetic epidemiology study. ⬇️

scientific article

Transcriptomic identification of ADH1B as a novel candidate gene for obesity and insulin resistance in human adipose tissue in Mexican Americans from the Veterans Administration Genetic Epidemiology Study (VAGES)

scientific article

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