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Authors whose works are in public domain in at least one jurisdiction

List of works by Maikel P Peppelenbosch

(Pro-)vitamin D as treatment option for hedgehog-related malignancies

scientific article published on 17 September 2007

5-Aminosalicylic acid inhibits cell cycle progression in a phospholipase D dependent manner in colorectal cancer.

scientific article

A Direct Effect of Sex Hormones on Epithelial Barrier Function in Inflammatory Bowel Disease Models

A MicroRNA Panel in Pancreatic Cyst Fluid for the Risk Stratification of Pancreatic Cysts in a Prospective Cohort

scientific article published on January 2016

A Relay Pathway between Arginine and Tryptophan Metabolism Confers Immunosuppressive Properties on Dendritic Cells

scientific article published on 13 February 2017

A comparative analysis by SAGE of gene expression profiles of Barrett's esophagus, normal squamous esophagus, and gastric cardia

scientific article published in October 2005

A comparative analysis by SAGE of gene expression profiles of esophageal adenocarcinoma and esophageal squamous cell carcinoma.

scientific article

A dual role for 7-dehydrocholesterol reductase in regulating Hedgehog signalling?

scientific article published on 01 October 2006

A dynamic perspective of RNAi library development.

scientific article

A mechanism for thrombin-dependent lung metastasis in patients with osteosarcoma

scientific article published on 9 March 2009

A phase I trial with transgenic bacteria expressing interleukin-10 in Crohn's disease

scientific article

A phospholipidomic analysis of all defined human plasma lipoproteins

scientific article

A possible anti-proliferative and anti-metastatic effect of irradiated riboflavin in solid tumours.

scientific article published in December 2007

A promising action of riboflavin as a mediator of leukaemia cell death

scientific article

A role for STAT5 in steroid-resistant UC?

scientific article published on 01 July 2006

A simplified qPCR method revealing tRNAome remodeling upon infection by genotype 3 hepatitis E virus

scientific article published on 04 March 2020

Absence of ABCG2-mediated mucosal detoxification in patients with active inflammatory bowel disease is due to impeded protein folding

scientific article published on 01 January 2012

Action and Function of Vitamin D in Digestive Tract Physiology and Pathology.

scientific article published on 28 December 2016

Action and function of Wnt/β-catenin signaling in the progression from chronic hepatitis C to hepatocellular carcinoma

scientific article published on 29 December 2016

Activated tumor-infiltrating CD4+ regulatory T cells restrain antitumor immunity in patients with primary or metastatic liver cancer

scientific article published on 04 December 2012

Activation of the canonical beta-catenin pathway by histamine

scientific article published on 16 October 2003

Acute stress elicited by bungee jumping suppresses human innate immunity

scientific article published on 10 December 2010

Adalimumab in Crohn's disease patients: pharmacokinetics in the first 6 months of treatment

scientific article published on 28 September 2014

Age-related obesity and type 2 diabetes dysregulate neuronal associated genes and proteins in humans

scientific article published on 18 August 2015

Altered bone morphogenetic protein signalling in theHelicobacter pylori-infected stomach

scientific article published on 01 June 2006

An ex vivo readout for evaluation of dendritic cell-induced autologous cytotoxic T lymphocyte responses against esophageal cancer

article

An improved protocol for generation of immuno-potent dendritic cells through direct electroporation of CD14+ monocytes.

scientific article published on 5 February 2007

Analysis of SHIP1 expression and activity in Crohn's disease patients

scientific article

Analytical and Sample Preparation Protocol for Therapeutic Drug Monitoring of 12 Thiopurine Metabolites Related to Clinical Treatment of Inflammatory Bowel Disease

Anchoring skeletal muscle development and disease: the role of ankyrin repeat domain containing proteins in muscle physiology

scientific article published on August 2010

Anti-inflammatory effects of a p38 mitogen-activated protein kinase inhibitor during human endotoxemia

scientific article

Anti-tumor effects of metformin in animal models of hepatocellular carcinoma: a systematic review and meta-analysis

scientific article

Antiviral or proviral action of mycophenolic acid in hepatitis B infection?

scientific article published on 01 October 2012

Are small GTPases signal hubs in sugar-mediated induction of fructan biosynthesis?

scientific article

Ascorbate-induced osteoblast differentiation recruits distinct MMP-inhibitors: RECK and TIMP-2.

scientific article published on 7 November 2008

Assessment of chromosomal gains as compared to DNA content changes is more useful to detect dysplasia in Barrett's esophagus brush cytology specimens

scientific article published on 01 May 2008

Autophagy mediates ER stress and inflammation in <i>Helicobacter pylori</i>-related gastric cancer

scientific article published on 01 January 2022

Bacterial Biofilms in Colorectal Cancer Initiation and Progression

scientific article published on 13 December 2016

Biological effects of propionic acid in humans; metabolism, potential applications and underlying mechanisms

scientific article published on 04 August 2010

Biological or pharmacological activation of protein kinase C alpha constrains hepatitis E virus replication

scientific article

Biological therapy in the management of recent-onset Crohn's disease: why, when and how?

scientific article published on January 2006

Biotech-Educated Platelets: Beyond Tissue Regeneration 2.0.

scientific article published on 23 August 2020

Blocking Wnt Secretion Reduces Growth of Hepatocellular Carcinoma Cell Lines Mostly Independent of β-Catenin Signaling

scientific article published on 13 November 2016

Bone marrow stromal cell interaction reduces syndecan-1 expression and induces kinomic changes in myeloma cells

scientific article published on 20 March 2010

Bone morphogenetic protein 2 is expressed by, and acts upon, mature epithelial cells in the colon.

scientific article published on January 2004

Bone morphogenetic protein 4 expressed in esophagitis induces a columnar phenotype in esophageal squamous cells.

scientific article

Bone morphogenetic protein signaling suppresses tumorigenesis at gastric epithelial transition zones in mice

scientific article

Bone morphogenetic protein-2 is a negative regulator of hepatocyte proliferation downregulated in the regenerating liver

scientific article published on December 2006

CCAAT/Enhancer-Binding Protein Delta (C/EBPδ): A Previously Unrecognized Tumor Suppressor that Limits the Oncogenic Potential of Pancreatic Ductal Adenocarcinoma Cells

scientific article published on 07 September 2020

CD5 expression promotes IL-10 production through activation of the MAPK/Erk pathway and upregulation of TRPC1 channels in B lymphocytes ⬇️

scientific article published on 8 August 2016

Calcineurin inhibitors stimulate and mycophenolic acid inhibits replication of hepatitis E virus

scientific article published on 26 February 2014

Cannabinoid Receptor Agonist Namisol Does Not Affect Cytokine Levels In Chronic Pancreatitis Patients

scientific article published on 01 August 2015

Cell biology of tissue factor, an unusual member of the cytokine receptor family.

scientific article

Characterization of coagulation factor synthesis in nine human primary cell types

scientific article

Chronic hepatitis E in solid-organ transplantation: the key implications of immunosuppressants

scientific article published on August 2014

Coagulation Factor Xa inhibits cancer cell migration via LIMK1-mediated cofilin inactivation

scientific article published on 26 March 2010

Coagulation factor Xa drives tumor cells into apoptosis through BH3-only protein Bim up-regulation

scientific article published on 19 April 2007

Coagulation factor Xa inhibits cancer cell migration via protease-activated receptor-1 activation

scientific article

Coagulation factor Xa signaling: the link between coagulation and inflammatory bowel disease?

scientific article published on 06 December 2008

Coagulation factors VIIa and Xa inhibit apoptosis and anoikis

scientific article published on January 2004

Common variants at the MHC locus and at chromosome 16q24.1 predispose to Barrett's esophagus

scientific article

Commonly observed RNF43 mutations retain functionality in attenuating Wnt/β-catenin signaling and unlikely confer Wnt-dependency onto colorectal cancers

scientific article published on 26 February 2020

Comparison of kinome profiles of Barrett's esophagus with normal squamous esophagus and normal gastric cardia.

scientific article

Comparison of peptide array substrate phosphorylation of c-Raf and mitogen activated protein kinase kinase kinase 8

scientific article

Concerted action of coagulation factors on cell survival.

scientific article published in April 2004

Consequence of functional Nod2 and Tlr4 mutations on gene transcription in Crohn’s disease patients

article

Contrasting roles of IL-12p40 and IL-12p35 in the development of hapten-induced colitis

scientific article published in January 2002

Convergent Transcription of Interferon-stimulated Genes by TNF-α and IFN-α Augments Antiviral Activity against HCV and HEV.

scientific article

Correction: Faria, A.V.S. et al., Targeting Tyrosine Phosphatases by 3-Bromopyruvate Overcomes Hyperactivation of Platelets from Gastrointestinal Cancer Patients. J. Clin. Med. 2019, 8, 936

scientific article published on 13 August 2020

Correlating Fecal Calprotectin With Hemoglobin Levels Within 1 Sample

scientific article published on 01 February 2018

Correspondence on “Microgravity Reduces the Differentiation and Regenerative Potential of Embryonic Stem Cells”

scientific article published on 15 March 2016

Cost-Effectiveness of Cetuximab for Advanced Esophageal Squamous Cell Carcinoma

scientific article

Cross Talk between Nucleotide Synthesis Pathways with Cellular Immunity in Constraining Hepatitis E Virus Replication

scientific article published on 29 February 2016

Cyclooxygenase-2 inhibition inhibits c-Met kinase activity and Wnt activity in colon cancer

scientific article published on February 2008

Cysteinyl leukotrienes mediate histamine hypersensitivity ex vivo by increasing histamine receptor numbers.

scientific article published on October 1999

Cytokeratin and CDX-2 expression in Barrett's esophagus

scientific article published on 01 January 2008

Cytopathological Analysis of Cyst Fluid Enhances Diagnostic Accuracy of Mucinous Pancreatic Cystic Neoplasms

scientific article

Cytoplasmic rods and rings in mycophenolic acid treatment

scientific article published on 26 July 2017

DMS triggers apoptosis associated with the inhibition of SPHK1/NF-κB activation and increase in intracellular Ca2+ concentration in human cancer cells

scientific article published on 30 October 2013

DNA array analysis of the effects of aspirin on colon cancer cells: involvement of Rac1

scientific article (publication date: July 2004)

DNA integrity as biomarker in pancreatic cyst fluid

scientific article published on August 2016

Defective ATG16L1-mediated removal of IRE1α drives Crohn's disease-like ileitis.

scientific article published on 12 January 2017

Depletion of Saccharomyces cerevisiae in psoriasis patients, restored by Dimethylfumarate therapy (DMF).

scientific article

Determination of thiopurine S-methyltransferase activity by hydrophilic interaction liquid chromatography hyphenated with mass spectrometry

scientific article published on 10 May 2017

Dichotomal effect of space flight-associated microgravity on stress-activated protein kinases in innate immunity

scientific article

Dichotomal effect of the coumadin derivative warfarin on inflammatory signal transduction

scientific article published on November 2002

Dichotomy between Lactobacillus rhamnosus and Klebsiella pneumoniae on dendritic cell phenotype and function

scientific article published on 13 December 2003

Dichotomy in Hedgehog signaling between human healthy vessel and atherosclerotic plaques

scientific article

Differential Sensitivities of Fast- and Slow-cycling Cancer Cells to Inosine Monophosphate Dehydrogenase 2 Inhibition by Mycophenolic Acid.

scientific article published on 13 October 2015

Digestive disease week 2011: highlights of clinical and preclinical research on Barrett's esophagus and associated esophageal adenocarcinoma.

scientific article published on 27 March 2012

Disparity of basal and therapeutically activated interferon signalling in constraining hepatitis E virus infection

scientific article published on December 2015

Distinct Antiviral Potency of Sofosbuvir Against Hepatitis C and E Viruses.

scientific article published in November 2016

Disulfide-induced self-assembled targets: A novel strategy for the label free colorimetric detection of DNAs/RNAs via unmodified gold nanoparticles

scientific article published on 7 April 2017

Diversity, compositional and functional differences between gut microbiota of children and adults

scientific article published on 23 January 2020

Do pregnancy-related changes in the microbiome stimulate innate immunity?

scientific article

Donor chimera model for tolerance induction in transplantation

scientific article published on 24 January 2013

Dynamics of Proliferative and Quiescent Stem Cells in Liver Homeostasis and Injury

scientific article published on 14 July 2017

E. coli-produced BMP-2 as a chemopreventive strategy for colon cancer: a proof-of-concept study

scientific article

Early bacterial dependent induction of inducible nitric oxide synthase (iNOS) in epithelial cells upon transfer of CD45RBhigh CD4+ T cells in a model for experimental colitis

scientific article published on 01 December 2007

Effect of aspirin on the Wnt/beta-catenin pathway is mediated via protein phosphatase 2A

scientific article (publication date: 19 October 2006)

Efficient automated assessment of genetic abnormalities detected by fluorescence in situ hybridization on brush cytology in a Barrett esophagus surveillance population

scientific article published on 01 May 2007

Endogenous hedgehog expression contributes to myocardial ischemia-reperfusion-induced injury

scientific article published on 14 May 2008

EphB2 activity plays a pivotal role in pediatric medulloblastoma cell adhesion and invasion

scientific article

Epidemiology and management of chronic hepatitis E infection in solid organ transplantation: a comprehensive literature review

scientific article

Epidermal growth factor activates calcium channels by phospholipase A2/5-lipoxygenase-mediated leukotriene C4 production

scientific article published in April 1992

Epidermal growth factor-activated calcium and potassium channels ⬇️

scientific article published on October 25, 1991

Erratum to: Action and function of Wnt/β-catenin signaling in the progression from chronic hepatitis C to hepatocellular carcinoma.

scientific article published on 11 October 2017

Essential role for the d-Asb11 cul5 Box domain for proper notch signaling and neural cell fate decisions in vivo

scientific article

Evaluation of AXIN1 and AXIN2 as targets of tankyrase inhibition in hepatocellular carcinoma cell lines

scientific article published on 02 April 2021

Evaluation of single-channel gating kinetics produced after amplitude-based separation of unitary currents

scientific article published in May 1995

Evidence for a minimal eukaryotic phosphoproteome?

scientific article

Expression of Hedgehog Pathway Components in the Adult Colon

scientific article published on 01 February 2006

Extracellular ligation-dependent CD45RB enzymatic activity negatively regulates lipid raft signal transduction

scientific article published on 7 October 2008

FVIIa:TF induces cell survival via G12/G13-dependent Jak/STAT activation and BclXL production

scientific article published on 11 March 2004

FXa-induced intracellular signaling links coagulation to neoangiogenesis: potential implications for fibrosis

scientific article published on 27 January 2009

Factor Xa stimulates proinflammatory and profibrotic responses in fibroblasts via protease-activated receptor-2 activation

scientific article published on 17 January 2008

Factor Xa: at the crossroads between coagulation and signaling in physiology and disease

scientific article published on 04 September 2008

Factors associated with ethnical disparity in overall survival for patients with hepatocellular carcinoma

scientific article published on 20 January 2017

Fatigue in patients with inflammatory bowel disease is associated with distinct differences in immune parameters.

scientific article

Fecal Matrix Metalloproteinase-9 Measurement for Optimizing Detection of Disease Activity in Inflammatory Bowel Disease

scientific article published on 01 May 2019

Fecal microbiota transfer may increase irritable bowel syndrome and inflammatory bowel diseases-associated bacteria

scientific article published on 24 February 2013

Feed a cold, starve a fever?

scientific article published on January 2002

Ferruginol suppresses survival signaling pathways in androgen-independent human prostate cancer cells

scientific article

From extracellular to intracellular targets, inhibiting MAP kinases in treatment of Crohn's disease

scientific article

Fumarates and Cancer

scientific article published on 13 December 2016

Functional genomic analyses of the gut microbiota for CRC screening

scientific article published on 17 September 2013

GNAS is not involved in gastrointestinal tumour formation in Peutz-Jeghers syndrome

scientific article published in September 2013

Gains and Amplifications of c-myc, EGFR, and 20.q13 Loci in the No Dysplasia-Dysplasia-Adenocarcinoma Sequence of Barrett's Esophagus

scientific article published on 01 June 2008

Galectins in atherosclerotic disease

scientific article published on July 2009

Gene expression profile comparison of Barrett's esophagus epithelial cell cultures and biopsies.

scientific article

Genetic host factors in Helicobacter pylori-induced carcinogenesis: Emerging new paradigms

scientific article published on 14 November 2017

Genetic polymorphism in ATG16L1 gene is associated with adalimumab use in inflammatory bowel disease.

scientific article published on 11 December 2017

Genetically Engineered Bacteria for Treating Human Disease

scientific article published on 28 July 2017

Genetically Modified Lactococcus lactis for Delivery of Human Interleukin-10 to Dendritic Cells

scientific article published on 27 July 2011

Genomic ATG16L1 risk allele-restricted Paneth cell ER stress in quiescent Crohn's disease

scientific article

Genotype-specific acquisition, evolution and adaptation of characteristic mutations in hepatitis E virus

scientific article

Glucocorticoids cause rapid dissociation of a T-cell-receptor-associated protein complex containing LCK and FYN ⬇️

scientific article

Glutathione peroxidase 7 prevents cancer in the oesophagus.

scientific article published on 29 June 2013

Guanylin and uroguanylin are produced by mouse intestinal epithelial cells of columnar and secretory lineage

scientific article published on 31 May 2016

Gut Microbiota Developments With Emphasis on Inflammatory Bowel Disease: Report From the Gut Microbiota for Health World Summit 2016.

scientific article

Hedgehog morphogen in cardiovascular disease

scientific article published on October 2006

Hedgehog signaling maintains chemoresistance in myeloid leukemic cells.

scientific article published on 30 August 2010

Hedgehog signalling as an antagonist of ageing and its associated diseases

scientific article published on 19 August 2012

Hedgehog turns lipoproteins into Janus-faced particles

scientific article published on October 2006

Hedgehog: an unusual signal transducer

scientific article published on April 2004

Helicobacter pylori Pathogenicity Factors Related to Gastric Cancer.

scientific article published on 17 December 2017

Hepatitis E Virus Infects Neurons and Brains.

scientific article published on 11 February 2017

High intra-uterine exposure to infliximab following maternal anti-TNF treatment during pregnancy

scientific article published on 01 March 2011

Human endotoxemia activates p38 MAP kinase and p42/44 MAP kinase, but not c-Jun N-terminal kinase.

scientific article published on November 2001

Human fecal microbiome-based biomarkers for colorectal cancer

scientific article

Human plasma very low density lipoprotein carries Indian hedgehog

scientific article

Human scFv SIgA expressed onLactococcus lactisas a vector for the treatment of mucosal disease

scientific article published on 01 August 2008

Hypoxia induces a hedgehog response mediated by HIF-1alpha

scientific article published in August 2009

IDH1 R132H decreases proliferation of glioma cell lines in vitro and in vivo

scientific article published on March 2011

IFN regulatory factor 1 restricts hepatitis E virus replication by activating STAT1 to induce antiviral IFN-stimulated genes

scientific article published on 21 June 2016

IL-6-induced DNMT1 activity mediates SOCS3 promoter hypermethylation in ulcerative colitis-related colorectal cancer

scientific article published on 27 June 2012

Identification of lineage-uncommitted, long-lived, label-retaining cells in healthy human esophagus and stomach, and in metaplastic esophagus.

scientific article

Identification of new possible targets for leukemia treatment by kinase activity profiling

scientific article published on 6 December 2010

Immunity against hepatitis E virus infection: Implications for therapy and vaccine development

scientific article published on 22 December 2017

Immunology of pre- and probiotic supplementation

scientific article published on 25 June 2008

Immunomodulatory effect of oxygen and pressure.

scientific article

Impact of human granulocyte and monocyte isolation procedures on functional studies

scientific article published on 2 May 2012

Impaired innate immunity in Crohn's disease

scientific article

Impeded protein folding and function in active inflammatory bowel disease

scientific article published on August 2011

Improved intra-array and interarray normalization of peptide microarray phosphorylation for phosphorylome and kinome profiling by rational selection of relevant spots

scientific article published on 26 May 2016

In silico tissue factor analysis: a bit-to-bit comparison

scientific article published on 01 March 2003

Increased PTP1B expression and phosphatase activity in colorectal cancer results in a more invasive phenotype and worse patient outcome

scientific article published on March 2016

Increased suppressor of cytokine signaling-3 expression predicts mucosal relapse in ulcerative colitis

scientific article published in January 2013

Indian Hedgehog is an antagonist of Wnt signaling in colonic epithelial cell differentiation

scientific article (publication date: March 2004)

Inflammatory signal transduction in Crohn's disease and novel therapeutic approaches

scientific article

Infliximab but not etanercept induces apoptosis in lamina propria T-lymphocytes from patients with Crohn's disease

scientific article

Infliximab induced T lymphocyte apoptosis in Crohn's disease.

scientific article

Infliximab treatment induces apoptosis of lamina propria T lymphocytes in Crohn's disease.

scientific article published on February 2002

Inhibition of Calcineurin or IMP Dehydrogenase Exerts Moderate to Potent Antiviral Activity against Norovirus Replication

scientific article published on 14 August 2017

Inhibition of coagulation, fibrinolysis, and endothelial cell activation by a p38 mitogen-activated protein kinase inhibitor during human endotoxemia

scientific article published on 06 February 2003

Inhibition of hepatitis E virus replication by proteasome inhibitor is nonspecific

scientific article

Inhibition of stress-activated MAP kinases induces clinical improvement in moderate to severe Crohn's disease ⬇️

scientific article published on January 1, 2002

Insights in dynamic kinome reprogramming as a consequence of MEK inhibition in MLL-rearranged AML.

scientific article published on 18 November 2013

Interleukin-10-based therapy for inflammatory bowel disease

scientific article

Invited review: Lipopolysaccharide recognition, internalisation, signalling and other cellular effects ⬇️

scientific article published on January 1, 2001

Kinase activity profiling of gram-negative pneumonia

scientific article

Kinase activity profiling of pneumococcal pneumonia

scientific article

Kinase activity profiling reveals active signal transduction pathways in pediatric acute lymphoblastic leukemia: a new approach for target discovery

scientific article published on 21 January 2015

Kinome analysis reveals nongenomic glucocorticoid receptor-dependent inhibition of insulin signaling

scientific article published on 30 March 2006

Kinome profiling

scientific article published on 07 August 2012

Kinome profiling for studying lipopolysaccharide signal transduction in human peripheral blood mononuclear cells

scientific article published on 7 September 2004

Kinome profiling in pediatric brain tumors as a new approach for target discovery

scientific article

Kinome profiling of clinical cancer specimens

scientific article published on 23 March 2010

Kinome profiling of non-canonical TRAIL signaling reveals RIP1-Src-STAT3-dependent invasion in resistant non-small cell lung cancer cells

scientific article

Kinome profiling of osteoblasts on hydroxyapatite opens new avenues on biomaterial cell signaling.

scientific article published on 11 June 2014

Kinome profiling of sugar signaling in plants using multiple platforms

scientific article

Kinome profiling using peptide arrays in eukaryotic cells

scientific article published on January 2009

Knocking down low molecular weight protein tyrosine phosphatase (LMW-PTP) reverts chemoresistance through inactivation of Src and Bcr-Abl proteins

scientific article

LGR5 marks targetable tumor-initiating cells in mouse liver cancer

scientific article published on 23 April 2020

LPS signal transduction: the picture is becoming more complex

scientific article published in January 2004

Lactobacillus rhamnosus induces peripheral hyporesponsiveness in stimulated CD4+ T cells via modulation of dendritic cell function

scientific article

Laminar shear stress-provoked cytoskeletal changes are mediated by epigenetic reprogramming of TIMP1 in human primary smooth muscle cells

scientific article published on 21 September 2018

Leptin Signaling in Human Peripheral Blood Mononuclear Cells, Activation of p38 and p42/44 Mitogen-Activated Protein (MAP) Kinase and p70 S6 Kinase

scientific article published on 01 September 2000

Letter in response to 'Coagulation and fibrosis in chronic liver disease'

scientific article published on 01 November 2009

Leukotriene synthesis is required for hedgehog-dependent neurite projection in neuralized embryoid bodies but not for motor neuron differentiation

scientific article

Linkage between genotype and immunological phenotype in Crohn's disease

scientific article

Linking risk conferring mutations in NCF4 to functional consequences in Crohn's disease: Figure 1 ⬇️

scientific article published on October 24, 2011

Lipid droplets hypertrophy: a crucial determining factor in insulin regulation by adipocytes

scientific article

Lipid phosphatase SHIP2 functions as oncogene in colorectal cancer by regulating PKB activation

scientific article published on 28 September 2016

Loss of SMAD4 alters BMP signaling to promote colorectal cancer cell metastasis via activation of Rho and ROCK.

scientific article published on 3 April 2014

Low dose Naltrexone for induction of remission in inflammatory bowel disease patients

scientific article published on 9 March 2018

Low molecular weight protein tyrosine phosphatase (LMWPTP) upregulation mediates malignant potential in colorectal cancer.

scientific article published on April 2015

Low-Molecular-Weight Protein Tyrosine Phosphatase Predicts Prostate Cancer Outcome by Increasing the Metastatic Potential

scientific article published on 6 July 2015

Macrophages present pinocytosed exogenous antigen via MHC class I whereas antigen ingested by receptor-mediated endocytosis is presented via MHC class II.

scientific article published on August 2000

Major remodelling of the murine stem cell kinome following differentiation in the hematopoietic compartment

scientific article published on 28 June 2011

Mapping of interactions between human macrophages and Staphylococcus aureus reveals an involvement of MAP kinase signaling in the host defense

scientific article

Maternal imprinting and female predominance in familial Crohn's disease

scientific article published on 23 January 2012

Meeting Report Europhosphatase 2015: Phosphatases as Drug Targets in Cancer

scientific article published on 7 January 2016

Meeting report on the first Sino-Dutch symposium on oncology

scientific article published on 16 March 2016

Mice lacking the multidrug resistance protein 1 are resistant to Streptococcus pneumoniae-induced pneumonia

scientific article

Miltefosine suppresses inflammation in a mouse model of inflammatory bowel disease

scientific article published in August 2013

Mitochondrial Fusion Via OPA1 and MFN1 Supports Liver Tumor Cell Metabolism and Growth

scientific article published on 04 January 2020

Mitogen activated protein (MAP) kinase signal transduction pathways and novel anti-inflammatory targets.

scientific article

Modeling rotavirus infection and antiviral therapy using primary intestinal organoids

scientific article published on 23 September 2015

Modulation of Human Peripheral Blood Mononuclear Cell Signaling by Medicinal Cannabinoids

scientific article published on 24 January 2017

Modulation of Src activity by low molecular weight protein tyrosine phosphatase during osteoblast differentiation

scientific article

Modulation of cytokine patterns and microbiome during pregnancy in IBD

scientific article published on 05 June 2019

Molecular Profile of Barrett's Esophagus and Gastroesophageal Reflux Disease in the Development of Translational Physiological and Pharmacological Studies

scientific article published on 03 September 2020

Molecular mechanism of violacein-mediated human leukemia cell death ⬇️

scientific article published on 6 May 2004

Monocytes and their pathophysiological role in Crohn's disease.

scientific article published on January 2009

Multiple signal transduction pathways regulate TNF-induced actin reorganization in macrophages: inhibition of Cdc42-mediated filopodium formation by TNF

scientific article published on 01 January 1999

Multipotent mesenchymal stromal cells in liver cancer: implications for tumor biology and therapy.

scientific article published on 06 September 2014

Mycophenolic acid potently inhibits rotavirus infection with a high barrier to resistance development

scientific article published on 25 July 2016

NF-kappaB, p38 MAPK and JNK are highly expressed and active in the stroma of human colonic adenomatous polyps

scientific article published on 01 February 2001

Natural compounds as a source of protein tyrosine phosphatase inhibitors: application to the rational design of small-molecule derivatives

scientific article published on 15 September 2006

Neuronal differentiation of embryonic stem cells.

scientific article published on June 1996

New insights into the role of STAT3 in IBD.

scientific article published on 12 October 2011

Noncanonical Antiviral Mechanisms of ISGs: Dispensability of Inducible Interferons

scientific article published on 2 December 2016

Nucleoside analogue 2'-C-methylcytidine inhibits hepatitis E virus replication but antagonizes ribavirin

scientific article published on 16 June 2017

On the road to understanding of the osteoblast adhesion: cytoskeleton organization is rearranged by distinct signaling pathways

scientific article

Oncophosphosignaling Favors a Glycolytic Phenotype in Human Drug Resistant Leukemia

scientific article published on 7 April 2017

Opportunities for Conventional and in Situ Cancer Vaccine Strategies and Combination with Immunotherapy for Gastrointestinal Cancers, A Review

scientific article published on 30 April 2020

Opposing Effects of Nitazoxanide on Murine and Human Norovirus

scientific article published in September 2017

Optimizing targeted cancer therapy: towards clinical application of systems biology approaches

scientific article published on May 2012

Osteoblast adhesion dynamics: a possible role for ROS and LMW-PTP.

scientific article published on June 2014

P38 mitogen activated protein kinase is involved in the downregulation of granulocyte CXC chemokine receptors 1 and 2 during human endotoxemia

scientific article published in January 2004

PAK2 is an effector of TSC1/2 signaling independent of mTOR and a potential therapeutic target for Tuberous Sclerosis Complex

scientific article

PI3K-Akt-mTOR axis sustains rotavirus infection via the 4E-BP1 mediated autophagy pathway and represents an antiviral target.

scientific article published on 5 May 2017

Palliative chemotherapy and targeted therapies for esophageal and gastroesophageal junction cancer.

scientific article published on 28 November 2017

Pancreatic cancer: promise for personalised medicine?

scientific article published on 13 December 2011

Pancreatic cyst fluid harbors a unique microbiome.

scientific article

Peripheral neutrophil functions and cell signalling in Crohn`s disease

scientific article

Phosphatidyl inositol-3-phosphate kinase mediates CD14 dependent signaling

scientific article published on 28 November 2006

Phosphoprotein levels, MAPK activities and NFkappaB expression are affected by fisetin.

scientific article

Phosphoproteome analysis reveals a critical role for hedgehog signalling in osteoblast morphological transitions.

scientific article published on 17 June 2017

Phosphoproteome profiling reveals critical role of JAK-STAT signaling in maintaining chemoresistance in breast cancer

scientific article published on 10 October 2017

Phosphoproteome reveals an atlas of protein signaling networks during osteoblast adhesion

scientific article

Polymorphisms near TBX5 and GDF7 are associated with increased risk for Barrett's esophagus ⬇️

scientific article

Prediction and Treatment of Radiation Enteropathy: Can Intestinal Bugs Lead the Way?

scientific article published on 06 September 2019

Prediction of antitumour necrosis factor clinical efficacy by real-time visualisation of apoptosis in patients with Crohn's disease

scientific article published on 2 November 2006

Preface to “Gut microbiome in health and disease”

article

Pregnane X receptor activation constrains mucosal NF-κB activity in active inflammatory bowel disease

scientific article published on 03 October 2019

Prevalence and Phenotype of Concurrent Psoriasis and Inflammatory Bowel Disease

scientific article published on 14 June 2017

Prevalence of Human Papillomavirus Infection in Women in the Autonomous Region of Inner Mongolia: a Population-based Study of a Chinese Ethnic Minority.

scientific article published on 29 June 2017

Profiling the changes in signaling pathways in ascorbic acid/β-glycerophosphate-induced osteoblastic differentiation

scientific article published on 01 January 2011

Prostanoids and prostanoid receptors in signal transduction

scientific article (publication date: July 2004)

Protease activated receptor-1 deficiency diminishes bleomycin-induced skin fibrosis

scientific article

Protease-activated receptor-2 induces myofibroblast differentiation and tissue factor up-regulation during bleomycin-induced lung injury: potential role in pulmonary fibrosis

scientific article published on 22 October 2010

Protein phosphatase 2A is required for mesalazine-dependent inhibition of Wnt/beta-catenin pathway activity

scientific article published on 25 May 2006

Protein phosphorylation and kinome profiling reveal altered regulation of multiple signaling pathways in B lymphocytes from patients with systemic lupus erythematosus

scientific article published in August 2010

Proteome of human plasma very low-density lipoprotein and low-density lipoprotein exhibits a link with coagulation and lipid metabolism

scientific article published on 6 February 2014

RIG-I is a key antiviral interferon-stimulated gene against hepatitis E virus regardless of interferon production.

scientific article published on 13 February 2017

Rac mediates growth factor-induced arachidonic acid release.

scientific article

Rac-dependent and -independent Pathways Mediate Growth Factor-induced Ca Influx

scientific article published on 01 April 1996

Rapamycin and everolimus facilitate hepatitis E virus replication: revealing a basal defense mechanism of PI3K-PKB-mTOR pathway

scientific article published on 22 May 2014

Rapid immunosuppressive effects of glucocorticoids mediated through Lck and Fyn.

scientific article published on 17 May 2005

Rationale of personalized immunosuppressive medication for hepatocellular carcinoma patients after liver transplantation

scientific article published on 27 January 2014

Receptor protein tyrosine phosphatase alpha activates pp60c-src and is involved in neuronal differentiation ⬇️

scientific article published on October 1, 1993

Reducing colorectal anastomotic leakage with tissue adhesive in experimental inflammatory bowel disease

scientific article published in May 2015

Regulation of p110delta PI 3-kinase gene expression

scientific article

Regulation of the p21Ras-MAP kinase pathway by factor VIIa

scientific article published on 01 May 2003

Reply to Wang et al

scientific article published on 01 April 2017

Report From the Falk Workshop on Microscopic Colitis: Creating Awareness for an Underappreciated Disease

scientific article published on 18 September 2012

Repression of smoothened by patched-dependent (pro-)vitamin D3 secretion

scientific article

Repurposing miltefosine for the treatment of immune-mediated disease?

scientific article published on 15 May 2014

Requirement of the eukaryotic translation initiation factor 4F complex in hepatitis E virus replication

scientific article published on 22 October 2015

Reversible phosphorylation in haematological malignancies: potential role for protein tyrosine phosphatases in treatment?

scientific article published on 24 July 2010

Riboflavin and photoproducts in MC3T3-E1 differentiation

scientific article published on 3 August 2010

Role of Neutrophil Recruitment in the Amelioration of Experimental Colitis by Genetic Ablation of Interleukin-21

scientific article published on 05 September 2008

Role of defective autophagia and the intestinal flora in Crohn disease

scientific article published on October 2010

Role of the immune system in pancreatic cancer progression and immune modulating treatment strategies.

scientific article

Rotavirus in organ transplantation: drug-virus-host interactions.

scientific article

Runt-related transcription factor 3 is associated with ulcerative colitis and shows epistasis with solute carrier family 22, members 4 and 5.

scientific article

Rupture of vulnerable atherosclerotic plaques: microRNAs conducting the orchestra?

scientific article published on February 2010

SMAD4 exerts a tumor-promoting role in hepatocellular carcinoma

scientific article published on 22 December 2014

SOCS3 in immune regulation of inflammatory bowel disease and inflammatory bowel disease-related cancer

scientific article published on 15 May 2012

STAT1, STAT6 and adenosine 3',5'-cyclic monophosphate (cAMP) signaling drive SOCS3 expression in inactive ulcerative colitis

scientific article

Sensitization of the histamine H1 receptor by increased ligand affinity

scientific article published in January 1998

Serum levels of caspase-cleaved cytokeratin 18 (CK18-Asp396) predict severity of liver disease in chronic hepatitis B.

scientific article published on 11 August 2017

Should Nivolumab-Induced Colitis Be Treated by Infliximab?

scientific article published on 18 May 2017

Similar Depletion of Protective Faecalibacterium prausnitzii in Psoriasis and Inflammatory Bowel Disease, but not in Hidradenitis Suppurativa

scientific article

Single cell proteomics for personalised medicine

scientific article

Sonic hedgehog expression correlates with fundic gland differentiation in the adult gastrointestinal tract.

scientific article published in June 2003

Sonic hedgehog induces transcription-independent cytoskeletal rearrangement and migration regulated by arachidonate metabolites

scientific article

Sonic hedgehog regulates gastric gland morphogenesis in man and mouse.

scientific article

Specific inhibition of c-Raf activity by semapimod induces clinical remission in severe Crohn's disease

scientific article published in August 2005

Staphylococcal PknB as the first prokaryotic representative of the proline-directed kinases

scientific article

Statins augment the chemosensitivity of colorectal cancer cells inducing epigenetic reprogramming and reducing colorectal cancer cell 'stemness' via the bone morphogenetic protein pathway

scientific article published on 6 May 2011

Steroid-Independent Crohn’s Disease Patients Also Benefit From Combination Therapy of Infliximab Plus Azathioprine

scientific article published on 01 October 2006

Superantigen-induced steroid resistance depends on activation of phospholipase Cβ2.

scientific article

Suppression of p21Rac signaling and increased innate immunity mediate remission in Crohn's disease

scientific article

Synergistic effect of methotrexate and infliximab on activated lymphocyte apoptosis

scientific article published on 01 January 2007

Systems medicine approaches for peptide array-based protein kinase profiling: progress and prospects

scientific article published on 31 May 2016

TF:FVIIa-specific activation of CREB upregulates proapoptotic proteins via protease-activated receptor-2.

scientific article published on 19 July 2008

TNFα contributes for attenuating both Y397FAK and Y416Src phosphorylations in osteoblasts.

scientific article published on 29 November 2013

Targeting Hedgehog signaling and understanding refractory response to treatment with Hedgehog pathway inhibitors

scientific article published on 19 August 2012

Targeting LKB1 signaling in cancer.

scientific article published on 31 December 2012

Targeting Tyrosine Phosphatases by 3-Bromopyruvate Overcomes Hyperactivation of Platelets from Gastrointestinal Cancer Patients

scientific article published on 28 June 2019

Targeting Viral Polymerase for Treating Hepatitis E Infection: How Far Are We?

scientific article published on 29 April 2016

Telaprevir/boceprevir era: from bench to bed and back

scientific article

Testing for Anti-PBP Antibody Is Not Useful in Diagnosing Autoimmune Pancreatitis

scientific article published on 21 June 2016

Tetrahydroxyquinone induces apoptosis of leukemia cells through diminished survival signaling

scientific article published in February 2006

The ATG16L1 risk allele associated with Crohn's disease results in a Rac1-dependent defect in dendritic cell migration that is corrected by thiopurines

scientific article published on 20 July 2016

The BMP pathway either enhances or inhibits the Wnt pathway depending on the SMAD4 and p53 status in CRC.

scientific article published on 13 November 2014

The Eukaryotic Translation Initiation Factor 4F Complex Restricts Rotavirus Infection via Regulating the Expression of IRF1 and IRF7 ⬇️

journal article from 'International Journal of Molecular Sciences' published in 2019

The RNA genome of hepatitis E virus robustly triggers antiviral interferon response

scientific article published in December 2017

The bone morphogenetic protein pathway is active in human colon adenomas and inactivated in colorectal cancer

scientific article published in January 2008

The bone morphogenetic protein pathway is inactivated in the majority of sporadic colorectal cancers

scientific article

The cell biology of the intestinal epithelium and its relation to inflammatory bowel disease

scientific article published on 03 January 2013

The coagulation factor Xa/protease activated receptor-2 axis in the progression of liver fibrosis: a multifaceted paradigm

scientific article

The effect of statins in colorectal cancer is mediated through the bone morphogenetic protein pathway

scientific article published on 14 August 2007

The gastrointestinal microbiota and its role in oncogenesis

scientific article published on 05 September 2017

The global burden of hepatitis E outbreaks: a systematic review.

scientific article

The long and winding road to rational treatment of cancer associated with LKB1/AMPK/TSC/mTORC1 signaling ⬇️

scientific article published on January 24, 2011

The microbiome and psoriatic arthritis

scientific article published on March 2014

The novel gene asb11: a regulator of the size of the neural progenitor compartment

scientific article

The pleiotropic effects of tissue factor: a possible role for factor VIIa-induced intracellular signalling?

scientific article (publication date: December 2001)

The role of protein tyrosine phosphatases in colorectal cancer

scientific article published on 13 April 2012

The role of receptor protein tyrosine phosphatase alpha in neuronal differentiation of embryonic stem cells.

scientific article published in February 1996

The ubiquitin-proteasome pathway mediates gelsolin protein downregulation in pancreatic cancer

scientific article published on September 2008

Therapeutic modulation of signal transduction pathways.

scientific article published on February 2004

Tissue factor and cancer metastasis: the role of intracellular and extracellular signaling pathways

scientific article published in January 2004

Tissue factor signal transduction in angiogenesis

scientific article

Transcriptional Regulation of Antiviral Interferon-Stimulated Genes

scientific article published on 27 January 2017

Transgenic probiotica as drug delivery systems: the golden bullet?

scientific article published on 01 January 2007

Treating Crohn's disease by inducing T lymphocyte apoptosis

scientific article

Tumor cell expression of immune inhibitory molecules and tumor-infiltrating lymphocyte count predict cancer-specific survival in pancreatic and ampullary cancer

scientific article

Tumor promotion through the mesenchymal stem cell compartment in human hepatocellular carcinoma.

scientific article published on 5 June 2013

Type I diabetes: a role for tissue factor in pancreatic islet transplantation?

scientific article published on 01 December 2002

UV activation of receptor tyrosine kinase activity.

scientific article published on August 1995

Unphosphorylated ISGF3 drives constitutive expression of interferon-stimulated genes to protect against viral infections.

scientific article published on 25 April 2017

VIIa/tissue factor interaction results in a tissue factor cytoplasmic domain-independent activation of protein synthesis, p70, and p90 S6 kinase phosphorylation

scientific article

Vagus nerve activity augments intestinal macrophage phagocytosis via nicotinic acetylcholine receptor alpha4beta2.

scientific article published on 7 May 2009

Vascular endothelial growth factor receptor 2 (VEGFR-2) signalling activity in paediatric pilocytic astrocytoma is restricted to tumour endothelial cells.

scientific article

Violacein induces death of resistant leukaemia cells via kinome reprogramming, endoplasmic reticulum stress and Golgi apparatus collapse

scientific article

Violacein synergistically increases 5-fluorouracil cytotoxicity, induces apoptosis and inhibits Akt-mediated signal transduction in human colorectal cancer cells

scientific article

Virus-host interactions in HBV-related hepatocellular carcinoma: more to be revealed?

scientific article published on 8 September 2014

Vitamin D Receptor Polymorphisms Are Associated with Reduced Esophageal Vitamin D Receptor Expression and Reduced Esophageal Adenocarcinoma Risk.

scientific article

Widespread deregulation of phosphorylation-based signaling pathways in multiple myeloma cells: opportunities for therapeutic intervention

scientific article published on 28 April 2011

Worsening of Bowel Symptoms Through Diet in Patients With Inflammatory Bowel Disease

scientific article published on 01 February 2016

Zeolite Nanoparticles for Selective Sorption of Plasma Proteins.

scientific article published on 30 November 2015

asb11 is a regulator of embryonic and adult regenerative myogenesis.

scientific article

d-Asb11 is an essential mediator of canonical Delta-Notch signalling

scientific article

mTOR is a promising therapeutical target in a subpopulation of pancreatic adenocarcinoma

scientific article published on 25 January 2014

p38 Mitogen-Activated Protein Kinase Inhibition Increases Cytokine Release by Macrophages In Vitro and During Infection In Vivo

scientific article published on 01 January 2001

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