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List of works by Francisco Ruiz-Pino

Acute inflammation reduces kisspeptin immunoreactivity at the arcuate nucleus and decreases responsiveness to kisspeptin independently of its anorectic effects.

scientific article published on 20 April 2010

Cellular distribution, regulated expression, and functional role of the anorexigenic peptide, NUCB2/nesfatin-1, in the testis

scientific journal article

Changes in Hypothalamic Expression of the Lin28/let-7 System and Related MicroRNAs During Postnatal Maturation and After Experimental Manipulations of Puberty

scientific article published on January 4, 2013

Characterization of the inhibitory roles of RFRP3, the mammalian ortholog of GnIH, in the control of gonadotropin secretion in the rat: in vivo and in vitro studies.

scientific article published on 27 April 2010

Characterization of the reproductive effects of the Vgf-derived peptide TLQP-21 in female rats: in vivo and in vitro studies.

scientific article

Characterization of the reproductive effects of the anorexigenic VGF-derived peptide TLQP-21: in vivo and in vitro studies in male rats.

scientific article

Critical roles of kisspeptins in female puberty and preovulatory gonadotropin surges as revealed by a novel antagonist

scientific article published in December 2009

Defining a novel leptin-melanocortin-kisspeptin pathway involved in the metabolic control of puberty

scientific article published on 11 August 2016

Differential modulation of gonadotropin responses to kisspeptin by aminoacidergic, peptidergic, and nitric oxide neurotransmission

scientific article

Direct Actions of Kisspeptins on GnRH Neurons Permit Attainment of Fertility but are Insufficient to Fully Preserve Gonadotropic Axis Activity.

scientific article

Disparate changes in kisspeptin and neurokinin B expression in the arcuate nucleus after sex steroid manipulation reveal differential regulation of the two KNDy peptides in rats

scientific article published on 22 July 2014

Early metabolic programming of puberty onset: impact of changes in postnatal feeding and rearing conditions on the timing of puberty and development of the hypothalamic kisspeptin system

scientific article published on 28 June 2011

Effects and interactions of tachykinins and dynorphin on FSH and LH secretion in developing and adult rats

scientific article

Environmentally Relevant Perinatal Exposures to Bisphenol A Disrupt Postnatal Kiss1/NKB Neuronal Maturation and Puberty Onset in Female Mice

scientific article published on 25 October 2019

Estradiol Regulates Energy Balance by Ameliorating Hypothalamic Ceramide-Induced ER Stress

scientific article published on 01 October 2018

Estradiol regulates brown adipose tissue thermogenesis via hypothalamic AMPK

scientific article

Gonadal hormone-dependent vs. -independent effects of kisspeptin signaling in the control of body weight and metabolic homeostasis

scientific article published on 19 June 2019

Hypothalamic miR-30 regulates puberty onset via repression of the puberty-suppressing factor, Mkrn3

scientific article published on 07 November 2019

Interactions between kisspeptin and neurokinin B in the control of GnRH secretion in the female rat.

scientific article

Intergenerational Influence of Paternal Obesity on Metabolic and Reproductive Health Parameters of the Offspring: Male-Preferential Impact and Involvement of Kiss1-Mediated Pathways

scientific article published on 22 December 2017

Metabolic and Gonadotropic Impact of Sequential Obesogenic Insults in the Female: Influence of the Loss of Ovarian Secretion.

scientific article published on 18 May 2015

Metabolic programming of puberty: sexually dimorphic responses to early nutritional challenges

scientific article published on 10 June 2013

Metabolic regulation of female puberty via hypothalamic AMPK-kisspeptin signaling

article published in the Proceedings of the National Academy of Sciences of the United States of America

Neurokinin B and the control of the gonadotropic axis in the rat: developmental changes, sexual dimorphism, and regulation by gonadal steroids.

scientific article

Obesity-induced hypogonadism in the male: premature reproductive neuroendocrine senescence and contribution of Kiss1-mediated mechanisms

scientific article published on January 2014

Physiological roles of gonadotropin-inhibitory hormone signaling in the control of mammalian reproductive axis: studies in the NPFF1 receptor null mouse

scientific article published on 13 May 2014

Pregnancy induces resistance to the anorectic effect of hypothalamic malonyl-CoA and the thermogenic effect of hypothalamic AMPK inhibition in female rats

scientific article

Role of neurokinin B in the control of female puberty and its modulation by metabolic status

scientific article published on February 2012

SF1-Specific AMPKα1 Deletion Protects Against Diet-Induced Obesity

scientific article published on 13 August 2018

SIRT1 mediates obesity- and nutrient-dependent perturbation of pubertal timing by epigenetically controlling Kiss1 expression

scientific article published in Nature Communications

Testicular expression of the Lin28/let-7 system: Hormonal regulation and changes during postnatal maturation and after manipulations of puberty.

scientific article

Tetrahydrocannabinolic acid A (THCA-A) reduces adiposity and prevents metabolic disease caused by diet-induced obesity

scientific article published on 09 November 2019

The anorexigenic neuropeptide, nesfatin-1, is indispensable for normal puberty onset in the female rat.

scientific article published on June 2010

The mammalian target of rapamycin as novel central regulator of puberty onset via modulation of hypothalamic Kiss1 system.

scientific article published on 4 September 2009

The orexigenic effect of orexin-A revisited: dependence of an intact growth hormone axis.

scientific article published on 16 July 2013

VCE-004.8, A Multitarget Cannabinoquinone, Attenuates Adipogenesis and Prevents Diet-Induced Obesity

scientific article published in Scientific Reports