List of works - Marko Novinec

A novel allosteric mechanism in the cysteine peptidase cathepsin K discovered by computational methods

scientific article

A novel photoaffinity-based probe for selective detection of cathepsin L active form

scientific article published on 04 November 2012

A simple and efficient protocol for the production of recombinant cathepsin V and other cysteine cathepsins in soluble form in Escherichia coli

scientific article

An allosteric site enables fine-tuning of cathepsin K by diverse effectors.

scientific article published on 17 November 2016

Calmodulin Is a Nonessential Activator of Secretory Phospholipase A2

scientific article published on 01 December 2009

Cathepsin K cleavage of SDF-1α inhibits its chemotactic activity towards glioblastoma stem-like cells.

scientific article published on 28 December 2016

Cathepsin K: a unique collagenolytic cysteine peptidase ⬇️

scientific article published on September 1, 2013

Clusterin is a specific stabilizer and liberator of extracellular cathepsin K ⬇️

scientific article published on March 10, 2012

Computational investigation of conformational variability and allostery in cathepsin K and other related peptidases

scientific article

Conformational flexibility and allosteric regulation of cathepsin K.

scientific article published in July 2010

Cysteine cathepsin activity regulation by glycosaminoglycans

scientific article published on 21 December 2014

Cytotoxic and peptidase inhibitory activities of selected non-hepatotoxic cyclic peptides from cyanobacteria.

scientific article

Diversity and evolution of the thyroglobulin type-1 domain superfamily

scientific article published on 20 December 2005

Human cathepsin L, a papain-like collagenase without proline specificity.

scientific article published on 26 August 2015

Inhibition of Human Cathepsins B and L by Caffeic Acid and Its Derivatives

scientific article published on 29 December 2020

Interaction between Human Cathepsins K, L, and S and Elastins

scientific article published in Journal of Biological Chemistry

Nicotiana benthamiana cathepsin B displays distinct enzymatic features which differ from its human relative and aleurain-like protease.

scientific article published on 9 July 2015

Orthocaspases are proteolytically active prokaryotic caspase homologues: the case of Microcystis aeruginosa.

scientific article

Papain-like peptidases: structure, function, and evolution

scientific article

Probing the activity modification space of the cysteine peptidase cathepsin K with novel allosteric modifiers

scientific article

Recombinant human SMOCs produced by in vitro refolding: calcium-binding properties and interactions with serum proteins.

scientific article published on 5 August 2008

Synthesis and biological evaluation of 7-(aminoalkyl)pyrazolo[1,5-a]pyrimidine derivatives as cathepsin K inhibitors

scientific article published on 19 November 2018

Synthesis of Novel 5-(N-Boc-N-Benzyl-2-aminoethyl)-7-oxo-4,7-dihydropyrazolo[1,5-a]pyrimidin-3-carboxamides and Their Inhibition of Cathepsins B and K.

scientific article published in December 2017

The catalytic domain of cathepsin C (dipeptidyl-peptidase I) alone is a fully functional endoprotease

scientific article published on 29 January 2019

The death enzyme CP14 is a unique papain-like cysteine proteinase with a pronounced S2 subsite selectivity.

scientific article

The heparin-binding activity of secreted modular calcium-binding protein 1 (SMOC-1) modulates its cell adhesion properties

scientific article

The papain-like cysteine proteinases NbCysP6 and NbCysP7 are highly processive enzymes with substrate specificities complementary to Nicotiana benthamiana cathepsin B.

scientific article

The two cathepsin B-like proteases of Arabidopsis thaliana are closely related enzymes with discrete endopeptidase and carboxydipeptidase activities

scientific article published on 01 September 2018

List of works by Marko Novinec

A novel allosteric mechanism in the cysteine peptidase cathepsin K discovered by computational methods

A novel photoaffinity-based probe for selective detection of cathepsin L active form

A simple and efficient protocol for the production of recombinant cathepsin V and other cysteine cathepsins in soluble form in Escherichia coli

An allosteric site enables fine-tuning of cathepsin K by diverse effectors.

Calmodulin Is a Nonessential Activator of Secretory Phospholipase A2

Cathepsin K cleavage of SDF-1α inhibits its chemotactic activity towards glioblastoma stem-like cells.

Cathepsin K: a unique collagenolytic cysteine peptidase ⬇️

Clusterin is a specific stabilizer and liberator of extracellular cathepsin K ⬇️

Computational investigation of conformational variability and allostery in cathepsin K and other related peptidases

Conformational flexibility and allosteric regulation of cathepsin K.

Cysteine cathepsin activity regulation by glycosaminoglycans

Cytotoxic and peptidase inhibitory activities of selected non-hepatotoxic cyclic peptides from cyanobacteria.

Diversity and evolution of the thyroglobulin type-1 domain superfamily

Human cathepsin L, a papain-like collagenase without proline specificity.

Inhibition of Human Cathepsins B and L by Caffeic Acid and Its Derivatives

Interaction between Human Cathepsins K, L, and S and Elastins

Nicotiana benthamiana cathepsin B displays distinct enzymatic features which differ from its human relative and aleurain-like protease.

Orthocaspases are proteolytically active prokaryotic caspase homologues: the case of Microcystis aeruginosa.

Papain-like peptidases: structure, function, and evolution

Probing the activity modification space of the cysteine peptidase cathepsin K with novel allosteric modifiers

Recombinant human SMOCs produced by in vitro refolding: calcium-binding properties and interactions with serum proteins.

Synthesis and biological evaluation of 7-(aminoalkyl)pyrazolo[1,5-a]pyrimidine derivatives as cathepsin K inhibitors

Synthesis of Novel 5-(N-Boc-N-Benzyl-2-aminoethyl)-7-oxo-4,7-dihydropyrazolo[1,5-a]pyrimidin-3-carboxamides and Their Inhibition of Cathepsins B and K.

The catalytic domain of cathepsin C (dipeptidyl-peptidase I) alone is a fully functional endoprotease

The death enzyme CP14 is a unique papain-like cysteine proteinase with a pronounced S2 subsite selectivity.

The heparin-binding activity of secreted modular calcium-binding protein 1 (SMOC-1) modulates its cell adhesion properties

The papain-like cysteine proteinases NbCysP6 and NbCysP7 are highly processive enzymes with substrate specificities complementary to Nicotiana benthamiana cathepsin B.

The two cathepsin B-like proteases of Arabidopsis thaliana are closely related enzymes with discrete endopeptidase and carboxydipeptidase activities