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List of works by Junichi Sadoshima

A Rab5 endosomal pathway mediates Parkin-dependent mitochondrial clearance.

scientific article

A case of primary dissecting aneurysm of the coronary artery

scientific article published on 01 September 1987

A functional interaction between Hippo-YAP signalling and FoxO1 mediates the oxidative stress response.

scientific article published on January 2014

A positive feedback loop of phosphodiesterase 3 (PDE3) and inducible cAMP early repressor (ICER) leads to cardiomyocyte apoptosis.

scientific article

A postprandial FGF19-SHP-LSD1 regulatory axis mediates epigenetic repression of hepatic autophagy

scientific article published on 26 April 2017

A redox-dependent mechanism for regulation of AMPK activation by Thioredoxin1 during energy starvation.

scientific article

A redox-dependent pathway for regulating class II HDACs and cardiac hypertrophy

scientific journal article

AMPK mediates autophagy during myocardial ischemia in vivo

scientific article published on 13 July 2007

ANG II type 1 receptor downregulation does not require receptor endocytosis or G protein coupling

scientific article published on 01 September 2001

AT1 receptor mutant lacking heterotrimeric G protein coupling activates the Src-Ras-ERK pathway without nuclear translocation of ERKs.

scientific article published on 3 January 2002

Ablation of the cardiac-specific gene leucine-rich repeat containing 10 (Lrrc10) results in dilated cardiomyopathy

scientific journal article

Actions of Ca2+ antagonists on two types of Ca2+ channels in rat aorta smooth muscle cells in primary culture.

scientific article published in August 1990

Activation of NADPH oxidase 4 in the endoplasmic reticulum promotes cardiomyocyte autophagy and survival during energy stress through the protein kinase RNA-activated-like endoplasmic reticulum kinase/eukaryotic initiation factor 2α/activating trans

scientific article published on 30 September 2013

Activation of PKN mediates survival of cardiac myocytes in the heart during ischemia/reperfusion.

scientific article

Activation of the cardiac proteasome during pressure overload promotes ventricular hypertrophy

scientific article published on 16 October 2006

Activation of γ2-AMPK Suppresses Ribosome Biogenesis and Protects Against Myocardial Ischemia/Reperfusion Injury.

scientific article published on 23 August 2017

Adenylyl cyclase type 5 disruption prolongs longevity and protects the heart against stress.

scientific article published on 24 December 2008

Adenylyl cyclase type 5 protein expression during cardiac development and stress.

scientific article published on 04 September 2009

Aggregate-prone R120GCRYAB triggers multifaceted modifications of the thioredoxin system

scientific article

Aging and Autophagy in the Heart

scientific article published on May 2016

Akt induces enhanced myocardial contractility and cell size in vivo in transgenic mice

scientific article

Akt mediates the cross-talk between beta-adrenergic and insulin receptors in neonatal cardiomyocytes.

scientific article published on 9 December 2004

Altered autonomic control in conscious transgenic rabbits with overexpressed cardiac Gsalpha

scientific article published on 01 February 2007

An Ideal PPAR Response Element Bound to and Activated by PPARα.

scientific article published on 4 August 2015

An angiotensin II type 1 receptor mutant lacking epidermal growth factor receptor transactivation does not induce angiotensin II-mediated cardiac hypertrophy

scientific article published on 10 August 2006

Angiotensin II activates RhoA in cardiac myocytes: a critical role of RhoA in angiotensin II-induced premyofibril formation

scientific article published on 01 April 1998

Angiotensin II and Oxidative Stress in the Failing Heart ⬇️

scientific article published on 03 May 2012

Angiotensin II and other hypertrophic stimuli mediated by G protein-coupled receptors activate tyrosine kinase, mitogen-activated protein kinase, and 90-kD S6 kinase in cardiac myocytes. The critical role of Ca(2+)-dependent signaling

scientific article published on 01 January 1995

Angiotensin II and serum differentially regulate expression of cyclins, activity of cyclin-dependent kinases, and phosphorylation of retinoblastoma gene product in neonatal cardiac myocytes

scientific article published on 01 February 1997

Angiotensin II–Induced Growth Responses in Isolated Adult Rat Hearts

article

Application of recombinant thioredoxin1 for treatment of heart disease.

scientific article published on 16 October 2010

Autocrine release of angiotensin II mediates stretch-induced hypertrophy of cardiac myocytes in vitro

scientific journal article

Autocrine secretion of angiotensin II mediates stretch-induced hypertrophy of cardiac myocytes in vitro

scientific article published on 01 January 1996

Autophagy in chronically ischemic myocardium.

scientific article

Autophagy in ischemic preconditioning and hibernating myocardium

scientific article published on 23 July 2009

Autophagy plays an essential role in mediating regression of hypertrophy during unloading of the heart

scientific article

Autophagy: a novel protective mechanism in chronic ischemia.

scientific article

BAG3 plays a central role in proteostasis in the heart.

scientific article

Beta-adrenergic cardiac hypertrophy is mediated primarily by the beta(1)-subtype in the rat heart.

scientific article

Bone marrow-derived cells contribute to fibrosis in the chronically failing heart

scientific article

Boosting autophagy in the diabetic heart: a translational perspective.

scientific article published on October 2015

Both hydrogen peroxide and transforming growth factor beta 1 contribute to endothelial Nox4 mediated angiogenesis in endothelial Nox4 transgenic mouse lines

scientific article published in December 2014

Broad suppression of NADPH oxidase activity exacerbates ischemia/reperfusion injury through inadvertent downregulation of hypoxia-inducible factor-1α and upregulation of peroxisome proliferator-activated receptor-α.

scientific article published on 8 March 2013

C2238 atrial natriuretic peptide molecular variant is associated with endothelial damage and dysfunction through natriuretic peptide receptor C signaling.

scientific article

Caffeine affects four different ionic currents in the bull-frog sympathetic neurone

scientific article published on 01 May 1989

Cardiac fibroblasts: the good, the bad, the ugly, the beautiful

scientific article

Cardiac-specific overexpression of AT1 receptor mutant lacking G alpha q/G alpha i coupling causes hypertrophy and bradycardia in transgenic mice.

scientific article

Cardiomyopathy in obesity, insulin resistance and diabetes

scientific article published on 14 March 2019

Cardioprotection and lifespan extension by the natural polyamine spermidine.

scientific article

Caspase-3 mediated cleavage of MEKK1 promotes p53 transcriptional activity

scientific journal article

Chelerythrine rapidly induces apoptosis through generation of reactive oxygen species in cardiac myocytes.

scientific article

Comparative analysis of mRNA isoform expression in cardiac hypertrophy and development reveals multiple post-transcriptional regulatory modules

scientific article

Constitutively active MEK1 rescues cardiac dysfunction caused by overexpressed GSK-3α during aging and hemodynamic pressure overload

scientific article published on 17 August 2012

Critical role of Mst1 in vascular remodeling after injury.

scientific article published on 16 June 2005

Cross-talk between PKA and Akt protects endothelial cells from apoptosis in the late ischemic preconditioning.

scientific article

Cyclic AMP modulates Ca-activated K channel in cultured smooth muscle cells of rat aortas

scientific article published on 01 October 1988

Cyclins and cyclin-dependent kinases are differentially regulated during terminal differentiation of C2C12 muscle cells.

scientific article published on June 1994

Cyclosporine reduces left ventricular mass with chronic aortic banding in mice, which could be due to apoptosis and fibrosis

scientific article published on 01 August 2001

Cytochrome c oxidase III as a mechanism for apoptosis in heart failure following myocardial infarction.

scientific article published on 22 July 2009

Cytokine actions of angiotensin II

scientific article published on 01 June 2000

DYRK2 negatively regulates cardiomyocyte growth by mediating repressor function of GSK-3β on eIF2Bε.

scientific article

Department of Cell Biology and Molecular Medicine, Rutgers New Jersey Medical School.

scientific article published in October 2017

Detrimental role of pericyte Nox4 in the acute phase of brain ischemia

scientific article published on 13 October 2015

Dietary restriction: standing up for sirtuins

scientific article published on August 2010

Dietary spermidine for lowering high blood pressure.

scientific article published on 24 January 2017

Different actions of intracellular free calcium on resting and GABA-gated chloride conductances

scientific article published on 01 February 1987

Differential roles of GSK-3β during myocardial ischemia and ischemia/reperfusion.

scientific article published on 7 July 2011

Disruption of type 5 adenylyl cyclase gene preserves cardiac function against pressure overload.

scientific article published on 6 August 2003

Distinct lipidomic profiles in models of physiological and pathological cardiac remodeling, and potential therapeutic strategies.

scientific article

Distinct roles of autophagy in the heart during ischemia and reperfusion: roles of AMP-activated protein kinase and Beclin 1 in mediating autophagy.

scientific article published in March 2007

Distinct roles of glycogen synthase kinase (GSK)-3alpha and GSK-3beta in mediating cardiomyocyte differentiation in murine bone marrow-derived mesenchymal stem cells.

scientific article published on 26 October 2009

Distinction of thioredoxin transnitrosylation and denitrosylation target proteins by the ICAT quantitative approach.

scientific article

Does Autophagy Mediate Cardiac Myocyte Death During Stress?

scientific article published on September 2016

Drp1-Dependent Mitochondrial Autophagy Plays a Protective Role Against Pressure Overload-Induced Mitochondrial Dysfunction and Heart Failure.

scientific article published on 25 February 2016

Effects of neostigmine and physostigmine on the acetylcholine receptor-ionophore complex in frog isolated sympathetic neurones ⬇️

scientific article published on June 1, 1988

Elimination of NADPH oxidase activity promotes reductive stress and sensitizes the heart to ischemic injury

scientific article published on 27 January 2014

Elucidating ERK2 function in the heart.

scientific article

Elucidation of thioredoxin target protein networks in mouse.

scientific article published on 04 May 2009

Endogenous Drp1 mediates mitochondrial autophagy and protects the heart against energy stress

scientific article published on 20 October 2014

Endogenous muscle atrophy F-box mediates pressure overload-induced cardiac hypertrophy through regulation of nuclear factor-kappaB.

scientific article published on 26 May 2011

Enhanced autophagy ameliorates cardiac proteinopathy.

scientific article published on November 2013

Enhancing the potential of cardiac progenitor cells: pushing forward with Pim-1.

scientific article

Evaluating mitochondrial autophagy in the mouse heart.

scientific article

Evaluation of the severity of mitral regurgitation by transesophageal Doppler flow echocardiography

scientific article published on 01 May 1992

Folliculin (Flcn) inactivation leads to murine cardiac hypertrophy through mTORC1 deregulation

scientific article

From Contractile Enhancement to Pathological Hypertrophy: Angiotensin II-Induced Nox2-Mediated Reactive Oxygen Species.

scientific article published in July 2015

Functional role of phosphodiesterase 3 in cardiomyocyte apoptosis: implication in heart failure

scientific journal article

GDF15, a cardioprotective TGF-beta superfamily protein

scientific article

Genetic inhibition of calcineurin induces diastolic dysfunction in mice with chronic pressure overload

scientific article published on 28 August 2009

Global changes in gene expression during cardiac hypertrophy: a new direction of cardiac signaling research

scientific article published on 03 July 2006

Glycogen synthase kinase-3alpha reduces cardiac growth and pressure overload-induced cardiac hypertrophy by inhibition of extracellular signal-regulated kinases

scientific article published on 12 September 2007

Glycogen synthase kinase-3beta: a novel regulator of cardiac hypertrophy and development.

scientific article

Glycogen synthase kinase-3β controls autophagy during myocardial ischemia and reperfusion.

scientific article published on January 2012

Guanylyl cyclase sensitivity to nitric oxide is protected by a thiol oxidation-driven interaction with thioredoxin-1.

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

scientific article

H11 has dose-dependent and dual hypertrophic and proapoptotic functions in cardiac myocytes.

scientific article published on June 2005

HAX-1 regulates SERCA2a oxidation and degradation

scientific article

Heart over mind: metabolic control of white adipose tissue and liver

scientific article

High efficiency gene transfer by multiple transfection protocol

scientific article published on 01 April 1999

How to be young at heart? miR-22 as a potential therapeutic target to boost autophagy and protect the old myocardium

scientific article published on February 2017

Hypotonic swelling-induced activation of PKN1 mediates cell survival in cardiac myocytes.

scientific article

Identification of novel nuclear targets of human thioredoxin 1

scientific article

Increased oxidative stress in the nucleus caused by Nox4 mediates oxidation of HDAC4 and cardiac hypertrophy.

scientific article

Inducible cAMP early repressor (ICER) is a negative-feedback regulator of cardiac hypertrophy and an important mediator of cardiac myocyte apoptosis in response to beta-adrenergic receptor stimulation.

scientific article

Inducible cAMP early repressor inhibits growth of vascular smooth muscle cell

scientific article published on 26 April 2007

Inhibition of endogenous Mst1 prevents apoptosis and cardiac dysfunction without affecting cardiac hypertrophy after myocardial infarction

scientific article published on 29 March 2007

Inhibition of endogenous thioredoxin in the heart increases oxidative stress and cardiac hypertrophy ⬇️

scientific article published on November 1, 2003

Inhibition of nicotinic acetylcholine response by atropine in frog isolated sympathetic neurons

scientific article published in January 1990

Inhibition of p38 alpha MAPK rescues cardiomyopathy induced by overexpressed beta 2-adrenergic receptor, but not beta 1-adrenergic receptor

scientific article published on 19 April 2007

Injection of wild type embryonic stem cells into Mst1 transgenic blastocysts prevents adult-onset cardiomyopathy.

scientific article published on June 2011

Inside-Out Signaling: Moving the AT1 Receptor in to Get the Message Out

scientific article published on 20 May 2015

Insulin resistance affects the cytoprotective effect of insulin in cardiomyocytes through an impairment of MAPK phosphatase-1 expression

scientific article published on 25 July 2007

Interacting with thioredoxin-1--disease or no disease?

scientific article published on 24 September 2012

Involvement of Mst1 in tumor necrosis factor-alpha-induced apoptosis of endothelial cells

scientific article

Is Raf1 a nexus for cardiac hypertrophic signaling in human disease?

scientific article

Is autophagy in response to ischemia and reperfusion protective or detrimental for the heart?

scientific article published on 19 December 2010

Is reactivation of autophagy a possible therapeutic solution for obesity and metabolic syndrome?

scientific article published on 11 May 2012

Is treating cardiac hypertrophy salutary or detrimental: the two faces of Janus

scientific article published on 01 April 2003

Ketone body can be a fuel substrate for failing heart

scientific article published on 01 September 2019

Kinetic properties of the caffeine-induced transient outward current in bull-frog sympathetic neurones

scientific article published on 01 February 1991

Knocking Out Angiotensin II in the Heart ⬇️

scientific article published on April 1, 2011

Loss of myocardial protection against myocardial infarction in middle-aged transgenic mice overexpressing cardiac thioredoxin-1

scientific article published on 25 February 2016

Low-voltage-activated calcium current in rat aorta smooth muscle cells in primary culture

scientific article published in September 1989

Mammalian target of rapamycin signaling in cardiac physiology and disease.

scientific article published on January 2014

Master redox regulator Trx1 upregulates SMYD1 & modulates lysine methylation.

scientific article

Mechanical stretch and angiotensin II differentially upregulate the renin-angiotensin system in cardiac myocytes In vitro

scientific article published on 01 July 1999

Mechanotransduction in stretch-induced hypertrophy of cardiac myocytes

scientific article published in January 1993

Meeting report for Basic Cardiovascular Sciences 2011 Scientific Sessions: from concept to clinic: leading cardiovascular translational science

scientific article published on 01 November 2011

Mending a broken heart: the role of mitophagy in cardioprotection

scientific article

Metabolic Reprogramming via PPARα Signaling in Cardiac Hypertrophy and Failure From Metabolomics to Epigenetics.

scientific article published on 23 June 2017

Mitochondrial autophagy in cardiomyopathy.

scientific article published on 19 March 2016

Mitophagy as a Protective Mechanism against Myocardial Stress.

scientific article published on 12 September 2017

Modulation of signaling mechanisms in the heart by thioredoxin 1.

scientific article

Molecular characterization of the stretch-induced adaptation of cultured cardiac cells. An in vitro model of load-induced cardiac hypertrophy

scientific article published on 01 May 1992

Molecular mechanisms for somatostatin inhibition of c-fos gene expression

scientific article published on 01 April 1997

Molecular mechanisms mediating mitochondrial dynamics and mitophagy and their functional roles in the cardiovascular system

scientific article

Molecular mechanisms of mitochondrial autophagy/mitophagy in the heart

scientific article

Mst1 inhibits autophagy by promoting the interaction between Beclin1 and Bcl-2.

scientific article published on 20 October 2013

Mst1 promotes cardiac myocyte apoptosis through phosphorylation and inhibition of Bcl-xL

scientific article

Mst1-mediated phosphorylation of Bcl-xL is required for myocardial reperfusion injury

scientific article published on April 2016

Muscle-specific RING finger 1 negatively regulates pathological cardiac hypertrophy through downregulation of calcineurin A.

scientific article

Myocardial injection with GSK-3β-overexpressing bone marrow-derived mesenchymal stem cells attenuates cardiac dysfunction after myocardial infarction.

scientific article published on 13 January 2011

Myosin light chain kinase mediates sarcomere organization during cardiac hypertrophy in vitro

scientific article published on 01 February 2000

NADPH oxidase 4 (Nox4) is a major source of oxidative stress in the failing heart.

scientific article

NADPH oxidase and cardiac failure.

scientific article published on 31 March 2010

NF2 Activates Hippo Signaling and Promotes Ischemia/Reperfusion Injury in the Heart.

scientific article published on 11 July 2016

NOX4 regulates autophagy during energy deprivation

scientific article published on 31 January 2014

Nanoparticle-Mediated Delivery of Mitochondrial Division Inhibitor 1 to the Myocardium Protects the Heart From Ischemia-Reperfusion Injury Through Inhibition of Mitochondria Outer Membrane Permeabilization: A New Therapeutic Modality for Acute Myoca

scientific article published on 22 July 2016

Negative regulators of cardiac hypertrophy.

scientific article published in August 2004

Neurally-mediated increase in calcineurin activity regulates cardiac contractile function in absence of hypertrophy

scientific article published on 01 September 2003

New insights into the molecular phenotype of eccentric hypertrophy.

scientific article published on 8 April 2010

New insights into the role of mitochondrial dynamics and autophagy during oxidative stress and aging in the heart

scientific article

Nicotinamide mononucleotide, an intermediate of NAD+ synthesis, protects the heart from ischemia and reperfusion

scientific article

Nicotinamide phosphoribosyltransferase regulates cell survival through NAD+ synthesis in cardiac myocytes.

scientific article published on 6 August 2009

Nicotinamide phosphoribosyltransferase regulates cell survival through autophagy in cardiomyocytes.

scientific article published on 8 November 2009

Nifedipine inhibits cardiac hypertrophy and left ventricular dysfunction in response to pressure overload.

scientific article published on May 2010

Novel AT(1) receptor-independent functions of losartan.

scientific article published in April 2002

Novel methods for measuring cardiac autophagy in vivo.

scientific article published on January 2009

Optimizing cell-based therapy for cardiac regeneration

scientific article published on 24 August 2009

Overcoming an energy crisis?: an adaptive role of glycogen synthase kinase-3 inhibition in ischemia/reperfusion

scientific article published in October 2008

Overexpressed cardiac Gsalpha in rabbits

scientific article published on 05 May 2006

Overview of pyridine nucleotides review series.

scientific article published on August 2012

Oxidative Stress Stimulates Autophagic Flux During Ischemia/Reperfusion ⬇️

scientific article published on January 27, 2011

PPARα-Sirt1 complex mediates cardiac hypertrophy and failure through suppression of the ERR transcriptional pathway.

scientific article published on November 2011

Pathophysiological roles of NADPH oxidase/nox family proteins in the vascular system. -Review and perspective-.

scientific article published on 15 June 2011

Peroxisome Proliferator Activated Receptor-α Association With Silent Information Regulator 1 Suppresses Cardiac Fatty Acid Metabolism in the Failing Heart

scientific article

Persistent stunning induces myocardial hibernation and protection: flow/function and metabolic mechanisms.

scientific article published on 15 May 2003

Pharmacological modulation of autophagy during cardiac stress.

scientific article published on September 2012

Phosphorylation of elk-1 by MEK/ERK pathway is necessary for c-fos gene activation during cardiac myocyte hypertrophy.

scientific article published in August 2000

Phosphorylation of eukaryotic translation initiation factor 2Bepsilon by glycogen synthase kinase-3beta regulates beta-adrenergic cardiac myocyte hypertrophy.

scientific article published on 4 March 2004

Physiological and pathological functions of NADPH oxidases during myocardial ischemia-reperfusion

scientific article

Pivotal role of miR-448 in the development of ROS-induced cardiomyopathy

scientific article

Poldip2 negatively regulates matrix synthesis at focal adhesions

scientific article published on 03 March 2016

Preconditioning effects of PKCdelta

scientific article published on 01 October 2005

Pressure overload induces greater hypertrophy and mortality in female mice with p38alpha MAPK inhibition

scientific article published on 22 August 2006

Proapoptotic Rassf1A/Mst1 signaling in cardiac fibroblasts is protective against pressure overload in mice ⬇️

scientific article published on September 20, 2010

Propranolol prevents enhanced stress signaling in Gs alpha cardiomyopathy: potential mechanism for beta-blockade in heart failure.

scientific article published in February 2004

Protection of the heart against ischemia/reperfusion by silent information regulator 1.

scientific article published on January 2011

Quantitative analysis of redox-sensitive proteome with DIGE and ICAT.

scientific article published on 16 August 2008

RASSF1A Signaling in the Heart: Novel Functions beyond Tumor Suppression

scientific article published on 10 April 2012

Rac1 Pharmacological Inhibition Rescues Human Endothelial Dysfunction

scientific article

Rag GTPases are cardioprotective by regulating lysosomal function.

scientific article

Rapamycin selectively inhibits angiotensin II-induced increase in protein synthesis in cardiac myocytes in vitro. Potential role of 70-kD S6 kinase in angiotensin II-induced cardiac hypertrophy

scientific article published on 01 December 1995

Rapid upregulation of CTGF in cardiac myocytes by hypertrophic stimuli: implication for cardiac fibrosis and hypertrophy

scientific article published on 01 August 2004

Recent progress in research on molecular mechanisms of autophagy in the heart

scientific article

Redox modification of cell signaling in the cardiovascular system

scientific article

Redox regulation of growth and death in cardiac myocytes

scientific article published on 01 September 2006

Redox regulatory mechanism of transnitrosylation by thioredoxin.

scientific article

Reduced phosphoinositide 3-kinase (p110alpha) activation increases the susceptibility to atrial fibrillation

scientific article published on 13 August 2009

Regulation of Cell Survival and Death by Pyridine Nucleotides ⬇️

scientific article published on August 17, 2012

Regulation of Myocardial Cell Growth and Death by the Hippo Pathway.

scientific article published on 10 June 2016

Regulation of autophagy by Beclin 1 in the heart

scientific journal article

Regulation of myocardial growth and death by NADPH oxidase ⬇️

scientific article published on 06 January 2011

Repetitive ischemia by coronary stenosis induces a novel window of ischemic preconditioning

scientific article published on 20 October 2008

Response by Shirakabe et al to Letter Regarding Article, "Drp1-Dependent Mitochondrial Autophagy Plays a Protective Role Against Pressure Overload-Induced Mitochondrial Dysfunction and Heart Failure".

scientific article published on August 2016

Rheb is a critical regulator of autophagy during myocardial ischemia: pathophysiological implications in obesity and metabolic syndrome.

scientific article published on 31 January 2012

Right-to-left shunt across atrial septal defect related to tricuspid regurgitation: assessment by transesophageal Doppler echocardiography

scientific article published on 01 March 1994

Role of NADPH oxidase in the regulation of autophagy in cardiomyocytes.

scientific article published in April 2015

Role of smooth muscle Nox4-based NADPH oxidase in neointimal hyperplasia

scientific article published on 12 November 2015

SUMOylation: a novel protein quality control modifier in the heart.

scientific article published on September 2014

Scientists on the Spot: Autophagy and heart disease

scientific article published on 01 August 2019

Selective activation of the "b" splice variant of phospholipase Cbeta1 in chronically dilated human and mouse atria

scientific article published on 31 August 2009

Sex differences in response to miRNA-34a therapy in mouse models of cardiac disease: identification of sex-, disease- and treatment-regulated miRNAs

scientific article

Signal transduction pathways of angiotensin II--induced c-fos gene expression in cardiac myocytes in vitro. Roles of phospholipid-derived second messengers

scientific article published on 01 September 1993

Silent information regulator 1 protects the heart from ischemia/reperfusion

scientific article published on 8 November 2010

Sirt1 carboxyl-domain is an ATP-repressible domain that is transferrable to other proteins.

scientific article

Sirt1 protects the heart from aging and stress.

scientific article published on March 2008

Sirt1 regulates aging and resistance to oxidative stress in the heart

scientific article published on 19 April 2007

Sirtuin 1 protects the aging heart from contractile dysfunction mediated through the inhibition of endoplasmic reticulum stress-mediated apoptosis in cardiac-specific Sirtuin 1 knockout mouse model.

scientific article published on 14 November 2016

Solving the cardiac hypertrophy riddle: The angiotensin II-mechanical stress connection

scientific article published in November 2013

Some properties of inhibitory action of lidocaine on the Ca2+ current of single isolated frog sensory neurons

scientific article

Specific role of the extracellular signal-regulated kinase pathway in angiotensin II-induced cardiac hypertrophy in vitro

scientific article

Stimulation of β-adrenoceptors up-regulates cardiac expression of galectin-3 and BIM through the Hippo signalling pathway

scientific article published on 30 May 2019

Suppression of ERR targets by a PPARα/Sirt1 complex in the failing heart ⬇️

scientific article published on March 1, 2012

The Akt-glycogen synthase kinase 3beta pathway regulates transcription of atrial natriuretic factor induced by beta-adrenergic receptor stimulation in cardiac myocytes

scientific article published on 01 May 2000

The Hippo signal transduction network in skeletal and cardiac muscle.

scientific article published on 05 August 2014

The MEKK1-JNK pathway plays a protective role in pressure overload but does not mediate cardiac hypertrophy.

scientific article

The NADPH oxidase Nox4 and aging in the heart.

scientific article published on December 2010

The Role of Autophagy in the Heart

scientific article published on 25 October 2017

The cellular and molecular response of cardiac myocytes to mechanical stress.

scientific article published on January 1997

The epidermal growth factor receptor is involved in angiotensin II but not aldosterone/salt-induced cardiac remodelling

scientific article

The function of nicotinamide phosphoribosyltransferase in the heart.

scientific article

The heterotrimeric G q protein-coupled angiotensin II receptor activates p21 ras via the tyrosine kinase-Shc-Grb2-Sos pathway in cardiac myocytes

scientific article

The importance of autophagy in cardioprotection

scientific article

The one-two punch: knocking out angiotensin II in the heart.

scientific article

The role of SUMO-1 in cardiac oxidative stress and hypertrophy.

scientific article published on 4 August 2014

The role of autophagy during ischemia/reperfusion

scientific article published on 18 March 2008

The role of autophagy in mediating cell survival and death during ischemia and reperfusion in the heart.

scientific article published on September 2007

The role of autophagy in the heart.

scientific article

The role of redox modulation of class II histone deacetylases in mediating pathological cardiac hypertrophy.

scientific article published on 08 May 2009

The role of sirtuins in cardiac disease

scientific article

The small-molecule BGP-15 protects against heart failure and atrial fibrillation in mice.

scientific article published on 9 December 2014

Thioredoxin 1 Negatively Regulates Angiotensin II–Induced Cardiac Hypertrophy Through Upregulation of miR-98/let-7 ⬇️

scientific article published on December 23, 2010

Thioredoxin 1 is essential for sodium sulfide-mediated cardioprotection in the setting of heart failure

scientific article published on 24 January 2013

Thioredoxin 1-mediated post-translational modifications: reduction, transnitrosylation, denitrosylation, and related proteomics methodologies.

scientific article

Thioredoxin-1 Attenuates Ventricular and Mitochondrial Postischemic Dysfunction in the Stunned Myocardium of Transgenic Mice

scientific article published on 21 March 2016

Thioredoxin-1 maintains mechanistic target of rapamycin (mTOR) function during oxidative stress in cardiomyocytes.

scientific article

Thioredoxin1 upregulates mitochondrial proteins related to oxidative phosphorylation and TCA cycle in the heart.

scientific article

Transesophageal echocardiographic findings of quadricuspid aortic valve

scientific article published on 01 September 1991

Translocation of caveolin regulates stretch-induced ERK activity in vascular smooth muscle cells.

scientific article published in May 2004

Two cases of dilated cardiomyopathy complicated by left ventricular aneurysm

scientific article published on 01 August 1987

Type 5 adenylyl cyclase disruption increases longevity and protects against stress

scientific article published on 01 July 2007

Tyrosine kinase FYN negatively regulates NOX4 in cardiac remodeling

scientific article published on 15 August 2016

Tyrosine kinases mediation of c-fos expression by cell swelling in cardiac myocytes

scientific article published on 01 January 1997

Unexpected Functional Consequences of the Loss of the Autophagy-Related Conjugation System

scientific article published on February 2017

Upregulation of Nox4 by hypertrophic stimuli promotes apoptosis and mitochondrial dysfunction in cardiac myocytes.

scientific article published on 25 February 2010

Upregulation of Rubicon promotes autosis during myocardial ischemia/reperfusion injury

scientific article published on 04 May 2020

Versatility of the angiotensin II type 1 receptor.

scientific article published in June 1998

Voltage-dependent anion-selective channels in cultured smooth muscle cells of the rat aorta

scientific article published on 01 January 1989

What Should We Learn From the Recent Decline of Basic Cardiovascular Science in Japan?

scientific article

What is the unique function of SAPK3/p38gamma in cardiac myocytes?

scientific article published on 01 June 2002

Why publish in the American Journal of Physiology-Heart and Circulatory Physiology?

scientific article published on 16 June 2017

YAP plays a crucial role in the development of cardiomyopathy in lysosomal storage diseases

scientific article published on 29 December 2020

Yes-associated protein isoform 1 (Yap1) promotes cardiomyocyte survival and growth to protect against myocardial ischemic injury

scientific article published on 30 December 2012

mTORC2 regulates cardiac response to stress by inhibiting MST1.

scientific article published on 2 April 2015

miR-206 Mediates YAP-Induced Cardiac Hypertrophy and Survival

scientific journal article

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