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List of works by Maria C Pedroso de Lima

A non-covalent strategy combining cationic lipids and CPPs to enhance the delivery of splice correcting oligonucleotides.

scientific article published on 30 March 2010

Acylation of the S4-PV cell-penetrating peptide as a means of enhancing its capacity to mediate nucleic acid delivery: Relevance of peptide/lipid interactions

scientific article published on 04 October 2018

African swine fever virus p10 protein exhibits nuclear import capacity and accumulates in the nucleus during viral infection.

scientific article

African swine fever virus p37 structural protein is localized in nuclear foci containing the viral DNA at early post-infection times.

scientific article

Allele-specific RNA silencing of mutant ataxin-3 mediates neuroprotection in a rat model of Machado-Joseph disease

scientific article

Application of thermoresponsive PNIPAAM-b-PAMPTMA diblock copolymers in siRNA delivery

scientific article published on 27 January 2014

Association of albumin or protamine to lipoplexes: enhancement of transfection and resistance to serum.

scientific article

Cationic lipid-DNA complexes in gene delivery: from biophysics to biological applications.

scientific article

Cationic liposomes for gene delivery

scientific article

CdTe quantum dots as fluorescent probes to study transferrin receptors in glioblastoma cells

scientific article published in October 2015

Cell-penetrating peptides as nucleic acid delivery systems: from biophysics to biological applications

scientific article published on January 2013

Cellular and molecular events associated with the antitumor response induced by the cytosine deaminase/5-fluorocytosine suicide gene therapy system in a rat liver metastasis model.

scientific article published on 22 June 2007

Cellular uptake of S4 13 -PV peptide occurs upon conformational changes induced by peptide–membrane interactions

scientific article published on 10 February 2006

Cholesterol affects African swine fever virus infection ⬇️

scientific article published on July 31, 1998

Cholesterol affects divalent cation-induced fusion and isothermal phase transitions of phospholipid membranes.

scientific article published in December 1988

Comparison of the Efficiency of Complexes Based on S413-PV Cell-Penetrating Peptides in Plasmid DNA and siRNA Delivery ⬇️

scientific article published on June 10, 2013

Cytotoxic effects of metal complexes of biogenic polyamines. I. Platinum(II) spermidine compounds: prediction of their antitumour activity.

scientific article published on February 2002

Delivery of antiviral agents in liposomes.

scientific article

Delivery of novel macromolecular drugs against HIV-1 ⬇️

scientific article published on November 1, 2001

Early miR-155 upregulation contributes to neuroinflammation in Alzheimer's disease triple transgenic mouse model.

scientific article

Enhancing glioblastoma cell sensitivity to chemotherapeutics: A strategy involving survivin gene silencing mediated by gemini surfactant-based complexes

scientific article published on 19 April 2016

Fluorescent probes for monitoring virus fusion kinetics: comparative evaluation of reliability.

scientific article published in March 2002

Gemini surfactants mediate efficient mitochondrial gene delivery and expression

scientific article published on 29 January 2015

Glucosylceramide synthase silencing combined with the receptor tyrosine kinase inhibitor axitinib as a new multimodal strategy for glioblastoma

scientific article published on 01 November 2019

High-throughput screening uncovers miRNAs enhancing glioblastoma cell susceptibility to tyrosine kinase inhibitors

scientific article

Human serum albumin enhances DNA transfection by lipoplexes and confers resistance to inhibition by serum.

scientific article

Impact of anti-PLK1 siRNA-containing F3-targeted liposomes on the viability of both cancer and endothelial cells.

scientific article published on 7 May 2013

In vitro cytotoxicity of a thermoresponsive gel system combining ethyl(hydroxyethyl) cellulose and lysine-based surfactants

scientific article published on 25 September 2012

In vitro modulation of Bcl-2 levels in small cell lung cancer cells: effects on cell viability.

scientific article

Inclusion of a single-tail amino acid-based amphiphile in a lipoplex formulation: effects on transfection efficiency and physicochemical properties.

scientific article

Increased gene delivery efficiency and specificity of a lipid-based nanosystem incorporating a glycolipid

scientific article published on 24 October 2014

Interaction of antimycobacterial and anti-pneumocystis drugs with phospholipid membranes.

scientific article published in March 1990

Interaction of cationic liposomes and their DNA complexes with monocytic leukemia cells

scientific article

Interactions of influenza virus with cultured cells: detailed kinetic modeling of binding and endocytosis.

scientific article

Intranasal Administration of Novel Chitosan Nanoparticle/DNA Complexes Induces Antibody Response to Hepatitis B Surface Antigen in Mice.

scientific article

Involvement of microRNA in microglia-mediated immune response

scientific article

Isolation of head and neck squamous carcinoma cancer stem-like cells in a syngeneic mouse model and analysis of hypoxia effect

scientific article

Kinetics of Influenza Virus Fusion with the Endosomal and Plasma Membranes of Cultured Cells. Effect of Temperature ⬇️

scientific article published on September 1, 2003

Lipid-Based Nanoparticles for siRNA Delivery in Cancer Therapy: Paradigms and Challenges ⬇️

scientific article published on 08 May 2012

Lysosomal Storage Disease-Associated Neuropathy: Targeting Stable Nucleic Acid Lipid Particle (SNALP)-Formulated siRNAs to the Brain as a Therapeutic Approach

scientific article published on 10 August 2020

Mechanistic study of the adjuvant effect of chitosan-aluminum nanoparticles

scientific article published on 19 September 2018

MiRNA-21 silencing mediated by tumor-targeted nanoparticles combined with sunitinib: A new multimodal gene therapy approach for glioblastoma.

scientific article published on 07 April 2015

MicroRNA deregulation and chemotaxis and phagocytosis impairment in Alzheimer's disease

scientific article published on 12 December 2015

MicroRNA modulation combined with sunitinib as a novel therapeutic strategy for pancreatic cancer.

scientific article

MicroRNA-21 silencing enhances the cytotoxic effect of the antiangiogenic drug sunitinib in glioblastoma

scientific article published on 30 November 2012

MicroRNAs as Molecular Targets for Cancer Therapy: On the Modulation of MicroRNA Expression.

scientific article published on 30 September 2013

Multimodal highly fluorescent-magnetic nanoplatform to target transferrin receptors in cancer cells

scientific article published on 21 August 2018

New serine-derived gemini surfactants as gene delivery systems

scientific article

Recent Trends in Nanotechnology Toward CNS Diseases: Lipid-Based Nanoparticles and Exosomes for Targeted Therapeutic Delivery.

scientific article published on 21 June 2016

Resveratrol stimulates the metabolic reprogramming of human CD4+ T cells to enhance effector function.

scientific article published on 17 October 2017

S4(13)-PV cell-penetrating peptide forms nanoparticle-like structures to gain entry into cells

scientific article published in April 2010

S4(13)-PV cell-penetrating peptide induces physical and morphological changes in membrane-mimetic lipid systems and cell membranes: implications for cell internalization

scientific article published on 31 December 2011

Silencing ataxin-3 mitigates degeneration in a rat model of Machado-Joseph disease: no role for wild-type ataxin-3?

scientific article published on 22 March 2010

Specific and efficient gene delivery mediated by an asialofetuin-associated nanosystem.

scientific article published on 19 July 2014

Striatal and nigral pathology in a lentiviral rat model of Machado-Joseph disease

scientific article

Suicide Gene Therapy for Oral Squamous Cell Carcinoma

scientific article published on 01 January 2019

Suicide gene therapy in cancer: where do we stand now?

scientific article

Survivin silencing as a promising strategy to enhance the sensitivity of cancer cells to chemotherapeutic agents.

scientific article published on 17 June 2011

Synergistic antitumoral effect of vinblastine and HSV-Tk/GCV gene therapy mediated by albumin-associated cationic liposomes.

scientific article published on 14 December 2007

Temperature-responsive cationic block copolymers as nanocarriers for gene delivery

scientific article published on 21 March 2013

Tf-lipoplexes for neuronal siRNA delivery: a promising system to mediate gene silencing in the CNS.

scientific article

Toward a siRNA-containing nanoparticle targeted to breast cancer cells and the tumor microenvironment

scientific article published on 19 May 2012

Transfection of oral cancer cells mediated by transferrin-associated lipoplexes: mechanisms of cell death induced by herpes simplex virus thymidine kinase/ganciclovir therapy.

scientific article published on 14 September 2006

Transferrin lipoplex-mediated suicide gene therapy of oral squamous cell carcinoma in an immunocompetent murine model and mechanisms involved in the antitumoral response.

scientific article

Transferrin-associated lipoplexes as gene delivery systems: relevance of mode of preparation and biophysical properties.

scientific article published on 21 February 2008

Tumor-targeted Chlorotoxin-coupled Nanoparticles for Nucleic Acid Delivery to Glioblastoma Cells: A Promising System for Glioblastoma Treatment.

scientific article published on 18 June 2013

Two African swine fever virus proteins derived from a common precursor exhibit different nucleocytoplasmic transport activities.

scientific article published on September 2004

Vanadium compounds as therapeutic agents: some chemical and biochemical studies.

scientific article published on 20 November 2008

miR-155 modulates microglia-mediated immune response by down-regulating SOCS-1 and promoting cytokine and nitric oxide production

article

siRNA delivery by a transferrin-associated lipid-based vector: a non-viral strategy to mediate gene silencing.

scientific article published on March 2007

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