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List of works by Thue W Schwartz

35th Annual Meeting of the European Association for the Study of Diabetes

article

35th Annual Meeting of the European Association for the Study of Diabetes : Brussels, Belgium, 28 September-2 October 1999

article

A broad-spectrum chemokine antagonist encoded by Kaposi's sarcoma-associated herpesvirus.

scientific article published on September 1997

A cDNA encoding a small common precursor for human pancreatic polypeptide and pancreatic icosapeptide

scientific article

A conserved aromatic lock for the tryptophan rotameric switch in TM-VI of seven-transmembrane receptors

scientific article published on 17 November 2009

A gut feeling for obesity: 7TM sensors on enteroendocrine cells

scientific article published in December 2008

A highly selective CCR2 chemokine agonist encoded by human herpesvirus 6.

scientific article

A library of 7TM receptor C-terminal tails. Interactions with the proposed post-endocytic sorting proteins ERM-binding phosphoprotein 50 (EBP50), N-ethylmaleimide-sensitive factor (NSF), sorting nexin 1 (SNX1), and G protein-coupled ...

scientific article

A major lineage of enteroendocrine cells coexpress CCK, secretin, GIP, GLP-1, PYY, and neurotensin but not somatostatin

scientific article published on 12 October 2012

A second disulfide bridge from the N-terminal domain to extracellular loop 2 dampens receptor activity in GPR39.

scientific article published on 12 August 2008

AMD3465, a monomacrocyclic CXCR4 antagonist and potent HIV entry inhibitor

scientific article published on September 2005

Activation of the CXCR3 chemokine receptor through anchoring of a small molecule chelator ligand between TM-III, -IV, and -VI

scientific article published on 14 December 2006

Ago-allosteric modulation and other types of allostery in dimeric 7TM receptors

scientific article

Agonists and inverse agonists for the herpesvirus 8-encoded constitutively active seven-transmembrane oncogene product, ORF-74

scientific article

Allosteric enhancers, allosteric agonists and ago-allosteric modulators: where do they bind and how do they act?

scientific article

An aromatic region to induce a switch between agonism and inverse agonism at the ghrelin receptor

scientific article published on 05 September 2012

An enteroendocrine full package solution

scientific article published on 01 June 2010

Analysis of selective binding epitopes for the kappa-opioid receptor antagonist nor-binaltorphimine.

scientific article published in June 1995

Atropine suppression test for pancreatic polypeptide

scientific article published on 01 July 1978

Autonomic innervation of the pancreas--an experimental model

scientific article published on 01 January 1982

Autonomic nervous control of the endocrine secretion from the isolated, perfused pig pancreas.

scientific article

Biased Gs versus Gq proteins and β-arrestin signaling in the NK1 receptor determined by interactions in the water hydrogen bond network

scientific article published on 12 August 2015

Biased signaling of lipids and allosteric actions of synthetic molecules for GPR119.

scientific article published on 25 August 2016

Binding epitopes for peptide and non-peptide ligands on the NK1 (substance P) receptor ⬇️

scientific article published on July 2, 1993

Binding of monoiodinated neuropeptide Y to hippocampal membranes and human neuroblastoma cell lines

scientific article published on 01 April 1989

Bioorthogonal Labeling of Ghrelin Receptor to Facilitate Studies of Ligand-Dependent Conformational Dynamics

scientific article published on 3 November 2015

Bioorthogonal fluorescent labeling of functional G-protein-coupled receptors

scientific article published on 18 July 2014

Biosynthesis of neuropeptide Y in porcine tissues and generation of N-terminal fragments in neuroblastoma cell lines

scientific article published on 01 January 1996

Biosynthesis of pancreatic polypeptide. Identification of a precursor and a co-synthesized product

scientific article published on 01 December 1980

Biosynthesis of peptide precursors and protease inhibitors using new constitutive and inducible eukaryotic expression vectors.

scientific article

Biosynthesis of tyrosine O-sulfated gastrins in rat antral mucosa

scientific article published on 01 November 1984

CC and CX3C chemokines differentially interact with the N terminus of the human cytomegalovirus-encoded US28 receptor

scientific article published on 16 November 2004

CD4-Chemokine receptor hybrids in human immunodeficiency virus type 1 infection.

scientific article published on September 1999

CHO cells synthesize amidated neuropeptide Y from a C-peptide deleted form of the precursor.

scientific article published on July 1991

Cat pancreatic eicosapeptide and its biosynthetic intermediate. Conservation of a monobasic processing site

scientific article published on November 1986

Cellular peptide processing after a single arginyl residue. Studies on the common precursor for pancreatic polypeptide and pancreatic icosapeptide

scientific article published on 01 April 1987

Cephalic phase of pancreatic-polypeptide secretion studied by sham feeding in man

scientific article published on January 1, 1979

Characterization of G-protein coupled receptor kinase interaction with the neurokinin-1 receptor using bioluminescence resonance energy transfer

scientific article

Characterization of glucagon-like peptide-1 receptor beta-arrestin 2 interaction: a high-affinity receptor phenotype

scientific article

Characterization of non-peptide antagonist and peptide agonist binding sites of the NK1 receptor with fluorescent ligands

scientific article published on 01 August 1997

Coexistence of peptide YY and glicentin immunoreactivity in endocrine cells of the gut

scientific article published on 01 July 1984

Common structural basis for constitutive activity of the ghrelin receptor family

scientific article

Comparison of peptidyl-glycine alpha-amidation activity in medullary thyroid carcinoma cells, pheochromocytomas, and serum

scientific article published on 01 August 1991

Conformational constraining of inactive and active States of a seven transmembrane receptor by metal ion site engineering in the extracellular end of transmembrane segment V.

scientific article published on 13 September 2006

Conservation of a helix-stabilizing dipole moment in the PP-fold family of regulatory peptides

scientific article published in 1993

Conserved water-mediated hydrogen bond network between TM-I, -II, -VI, and -VII in 7TM receptor activation

scientific article published on 15 April 2010

Constitutive Activity of Glucagon Receptor Mutants ⬇️

scientific article published on January 1, 1998

Constitutive ghrelin receptor activity as a signaling set-point in appetite regulation

scientific article published on March 2004

Construction of a high affinity zinc switch in the kappa-opioid receptor.

scientific article

Construction of covalently coupled, concatameric dimers of 7TM receptors

scientific article published in January 2009

Conversion of antagonist-binding site to metal-ion site in the tachykinin NK-1 receptor.

scientific article published on March 1995

Deficiency of the GPR39 receptor is associated with obesity and altered adipocyte metabolism

scientific journal article

Different binding epitopes on the NK1 receptor for substance P and non-peptide antagonist.

scientific article published in March 1993

Differential sensitivity to somatostatin of pancreatic polypeptide, glucagon and insulin secretion from the isolated perfused canine pancreas

scientific article published on 01 December 1979

Differential stimulation of pancreatic-polypeptide and gastrin secretion by bombesin in man

scientific article published on 01 June 1981

Dissecting signaling and functions of adhesion G protein-coupled receptors.

scientific article published on 7 December 2012

Distinct in vitro interaction pattern of dopamine receptor subtypes with adaptor proteins involved in post-endocytotic receptor targeting

scientific article

Disulfide bridge engineering in the tachykinin NK1 receptor

scientific article published on 01 February 2000

Diurnal profile of pancreatic polypeptide, pancreatic glucagon, gut glucagon and insulin in human morbid obesity

scientific article published on 01 January 1983

Downregulation of 5-HT7 Serotonin Receptors by the Atypical Antipsychotics Clozapine and Olanzapine. Role of Motifs in the C-Terminal Domain and Interaction with GASP-1.

scientific article published on 20 April 2015

Dual agonistic and antagonistic property of nonpeptide angiotensin AT1 ligands: susceptibility to receptor mutations

scientific article published on 01 February 1997

EBI2 overexpression in mice leads to B1 B-cell expansion and chronic lymphocytic leukemia-like B-cell malignancies

scientific article published on 21 December 2016

Effect of amino acid analogs on the processing of the pancreatic polypeptide precursor in primary cell cultures ⬇️

scientific article published on August 15, 1988

Effects of PYY3–36 and GLP-1 on energy intake, energy expenditure, and appetite in overweight men

scientific article published on 15 April 2014

Efficient amidation of C-peptide deleted NPY precursors by non-endocrine cells is affected by the presence of Lys-Arg at the C-terminus.

scientific article published on February 1993

Engineering of metal-ion sites as distance constraints in structural and functional analysis of 7TM receptors ⬇️

scientific article published on January 1, 1997

Enhanced fluorescence resonance energy transfer between spectral variants of green fluorescent protein through zinc-site engineering

scientific article published on 01 January 2001

Enteroendocrine cell types revisited

scientific article published on 17 October 2013

Evidence for a common molecular mode of action for chemically distinct nonpeptide antagonists at the neurokinin-1 (substance P) receptor

scientific article published on 01 March 1994

Evidence that a deviation in the kynurenine pathway aggravates atherosclerotic disease in humans

scientific article published on 14 August 2020

Exome sequencing-driven discovery of coding polymorphisms associated with common metabolic phenotypes.

scientific article published on 19 November 2012

Expression and precursor processing of neuropeptide Y in human and murine neuroblastoma and pheochromocytoma cell lines

scientific article published on 01 December 1989

Expression and precursor processing of neuropeptide Y in human pheochromocytoma and neuroblastoma tumors

scientific article published on 01 December 1989

Expression of the short chain fatty acid receptor GPR41/FFAR3 in autonomic and somatic sensory ganglia

scientific article published on 28 January 2015

Family and population-based studies of variation within the ghrelin receptor locus in relation to measures of obesity

scientific article

Fluorescence detection of picomol amounts of the phenylthiohydantoin derivative of histidine in thin-layer chromatography

scientific article published on 01 September 1984

Functional and genetic epidemiological characterisation of the FFAR4 (GPR120) p.R270H variant in the Danish population

scientific article published on 11 April 2016

G protein-coupled receptor 39 deficiency is associated with pancreatic islet dysfunction

scientific journal article

G protein-coupled receptor modulation with pepducins: moving closer to the clinic

scientific article published on 01 May 2011

GLP1- and GIP-producing cells rarely overlap and differ by bombesin receptor-2 expression and responsiveness

scientific article published on 19 October 2015

GPCR-Mediated Signaling of Metabolites

scientific article published on April 2017

GPR119 as a fat sensor

scientific article published on 02 May 2012

GPR119, a Major Enteroendocrine Sensor of Dietary Triglyceride Metabolites Coacting in Synergy With FFA1 (GPR40).

scientific article published on 25 October 2016

GPR39 signaling is stimulated by zinc ions but not by obestatin

scientific article

GPR39 splice variants versus antisense gene LYPD1: expression and regulation in gastrointestinal tract, endocrine pancreas, liver, and white adipose tissue

scientific article

GPR40 (FFAR1) - Combined Gs and Gq signaling in vitro is associated with robust incretin secretagogue action ex vivo and in vivo

scientific article

GPR41/FFAR3 and GPR43/FFAR2 as cosensors for short-chain fatty acids in enteroendocrine cells vs FFAR3 in enteric neurons and FFAR2 in enteric leukocytes

scientific article published on 24 July 2013

Genome-wide association study identifies eight loci associated with blood pressure

scientific article (publication date: June 2009)

Getting from A to B-exploring the activation motifs of the class B adhesion G protein-coupled receptor subfamily G member 4/GPR112.

scientific article published on 28 January 2016

Ghrelin receptor inverse agonists: identification of an active peptide core and its interaction epitopes on the receptor

scientific article published on 23 June 2006

Ghrelin receptor mutations--too little height and too much hunger

scientific article

Ghrelin.

scientific article

GluVII:06--a highly conserved and selective anchor point for non-peptide ligands in chemokine receptors

scientific article published on January 2006

Glucagon and glucagon-like peptide 1: selective receptor recognition via distinct peptide epitopes

scientific article published on 01 December 1994

Glucagon, glicentin, proglucagon, PYY, PP and proPP-icosapeptide immunoreactivities of rectal carcinoid tumors and related non-tumor cells

scientific article published in January 1987

Glucose metabolism is altered after loss of L cells and α-cells but not influenced by loss of K cells ⬇️

scientific article published on October 31, 2012

Gq and Gs signaling acting in synergy to control GLP-1 secretion

scientific article published on 28 November 2016

High constitutive activity of a virus-encoded seven transmembrane receptor in the absence of the conserved DRY motif (Asp-Arg-Tyr) in transmembrane helix 3.

scientific article

High constitutive signaling of the ghrelin receptor--identification of a potent inverse agonist

scientific article (publication date: November 2003)

High molecular weight PEGylation of human pancreatic polypeptide at position 22 improves stability and reduces food intake in mice

scientific article published on 21 August 2016

High-performance liquid chromatography of phenylthiocarbamyl derivatives of amino acids and side-chain derivatized amino acids

scientific article published on 01 March 1987

How receptor mutagenesis may confirm or confuse receptor classification.

scientific article published on May 1997

Human pancreatic icosapeptide: isolation, sequence, and immunocytochemical localization of the COOH-terminal fragment of the pancreatic polypeptide precursor ⬇️

scientific article published on February 1, 1984

Human substance P receptor binding mode of the antagonist drug aprepitant by NMR and crystallography

scientific article published in Nature Communications

Hypotension induced by passive head-up tilt: endocrine and circulatory mechanisms

scientific article published on 01 October 1986

Identification of an efficacy switch region in the ghrelin receptor responsible for interchange between agonism and inverse agonism

scientific article published on 19 March 2007

Identification of peptide binding residues in the extracellular domains of the AT1 receptor

scientific article published on 01 December 1994

Immunochemical studies on gastrins in the urine ⬇️

scientific article published on November 1, 1978

Immunochemical studies on macromolecular gastrins: evidence that "big big gastrins" are artifacts in blood and mucosa, but truly present in some large gastrinomas

scientific article published in September 1977

Immunohistochemical and chromatographic identification of peptides derived from proneuropeptide Y in the human frontal cortex.

scientific article published in January 1993

Impaired alpha-carboxyamidation of gastrin in vitamin C-deficient guinea pigs.

scientific article

Impaired pancreatic innervation after pyloric transsection in dogs. Reduced pancreatic polypeptide response to insulin hypoglycaemia

scientific article published on 01 January 1983

Impaired pancreatic innervation after selective gastric vagotomy. Reduction of the pancreatic polypeptide response to food and insulin hypoglycemia

scientific article published on 01 January 1981

Impaired pancreatic polypeptide response to a meal in type 1 diabetic patients: vagal neuropathy or islet cell dysfunction?

scientific article published on 01 March 1993

Impaired response of pancreatic polypeptide to hypoglycaemia: an early sign of autonomic neuropathy in diabetics.

scientific article published in December 1979

Implications of replacing peptide bonds in the COOH-terminal B chain domain of insulin by the psi (CH2-NH) linker.

scientific article

Importance of constitutive activity and arrestin-independent mechanisms for intracellular trafficking of the ghrelin receptor

scientific article published on 23 August 2007

In Silico Investigation of the Neurotensin Receptor 1 Binding Site: Overlapping Binding Modes for Small Molecule Antagonists and the Endogenous Peptide Agonist

scientific article published on 16 September 2015

Increase in vagal activity during hypotensive lower-body negative pressure in humans

scientific article published on 01 July 1988

Increased serum pancreatic polypeptide and serum gastrin secretion in patients with functional dyspepsia: correlation to the shape of the duodenal loop

Inhibition of human immunodeficiency virus replication by a dual CCR5/CXCR4 antagonist

scientific article published on December 2004

Interaction between the nonpeptide angiotensin antagonist SKF-108,566 and histidine 256 (HisVI:16) of the angiotensin type 1 receptor

scientific article published on 01 March 1995

Interaction of NPY and VIP in regulation of myometrial blood flow and mechanical activity

scientific article published on 01 March 1988

Interaction of a non-peptide agonist with angiotensin II AT1 receptor mutants

scientific article

International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G protein-coupled receptors

scientific article

Isolation and biogenesis of a new peptide from pancreatic islets

scientific article published on 01 December 1981

Isolation of ovine pancreatic icosapeptide: a peptide product containing one cysteine residue

scientific article published on 01 March 1984

Kaposi sarcoma-associated herpes virus targets the lymphotactin receptor with both a broad spectrum antagonist vCCL2 and a highly selective and potent agonist vCCL3

scientific article

Ligand binding and micro-switches in 7TM receptor structures

scientific article published on 16 April 2009

Ligand modulation of the Epstein-Barr virus-induced seven-transmembrane receptor EBI2: identification of a potent and efficacious inverse agonist

scientific article

Lipolysis drives expression of the constitutively active receptor GPR3 to induce adipose thermogenesis

scientific article published in 2021

Localization of HCMV UL33 and US27 in endocytic compartments and viral membranes

scientific article published on March 2002

Locating ligand-binding sites in 7TM receptors by protein engineering.

scientific article published on August 1994

Long-acting lipidated analogue of human pancreatic polypeptide is slowly released into circulation

scientific article

MC148 encoded by human molluscum contagiosum poxvirus is an antagonist for human but not murine CCR8.

scientific article

MTNR1B G24E variant associates With BMI and fasting plasma glucose in the general population in studies of 22,142 Europeans

scientific article

Mapping substance P binding sites on the neurokinin-1 receptor using genetic incorporation of a photoreactive amino acid

scientific article

Mechanism of pancreatic-polypeptide release

scientific article published on 01 March 1977

Metal ion enhanced binding of AMD3100 to Asp262 in the CXCR4 receptor

scientific article published in January 2003

Metal ion site engineering indicates a global toggle switch model for seven-transmembrane receptor activation

scientific article published on 27 March 2006

Metal ion-mediated agonism and agonist enhancement in melanocortin MC1 and MC4 receptors

scientific article published on 18 September 2002

Metal-ion sites as structural and functional probes of helix-helix interactions in 7TM receptors.

scientific article published on April 1997

Misuse of gastrin radioimmunoassay kits

scientific article published on 01 August 1983

Model-Based Discovery of Synthetic Agonists for the Zn2+-Sensing G-Protein-Coupled Receptor 39 (GPR39) Reveals Novel Biological Functions

scientific article

Modest human immunodeficiency virus coreceptor function of CXCR3 is strongly enhanced by mimicking the CXCR4 ligand binding pocket in the CXCR3 receptor

scientific article published on 24 January 2007

Modulation of constitutive activity and signaling bias of the ghrelin receptor by conformational constraint in the second extracellular loop

scientific article published on 30 July 2012

Molecular basis for agonism in the BB3 receptor: an epitope located on the interface of transmembrane-III, -VI, and -VII.

scientific article

Molecular determinants of receptor binding and signaling by the CX3C chemokine fractalkine.

scientific article

Molecular dynamics-guided discovery of an ago-allosteric modulator for GPR40/FFAR1

scientific article published on 14 March 2019

Molecular interaction of a potent nonpeptide agonist with the chemokine receptor CCR8

scientific article published on 01 August 2007

Molecular mechanism of 7TM receptor activation--a global toggle switch model

scientific article

Molecular mechanism of AMD3100 antagonism in the CXCR4 receptor: transfer of binding site to the CXCR3 receptor

scientific article published on 28 October 2003

Molecular mechanism of Zn2+ agonism in the extracellular domain of GPR39.

scientific article

Molecular mechanism of action of monocyclam versus bicyclam non-peptide antagonists in the CXCR4 chemokine receptor

scientific article

Molecular mechanism of agonism and inverse agonism in the melanocortin receptors: Zn(2+) as a structural and functional probe

scientific article

Molecular pharmacological phenotyping of EBI2. An orphan seven-transmembrane receptor with constitutive activity

scientific article

Murine cytomegalovirus (CMV) M33 and human CMV US28 receptors exhibit similar constitutive signaling activities

scientific article

Mutation-Guided Unbiased Modeling of the Fat Sensor GPR119 for High-Yield Agonist Screening

scientific article published on 29 October 2015

Mutational evidence for a common kappa antagonist binding pocket in the wild-type kappa and mutant mu[K303E] opioid receptors.

scientific article published in December 1998

Mutations along transmembrane segment II of the NK-1 receptor affect substance P competition with non-peptide antagonists but not substance P binding.

scientific article published on November 1994

Mutations at the CXCR4 interaction sites for AMD3100 influence anti-CXCR4 antibody binding and HIV-1 entry

scientific article published in July 2003

Mutations in transmembrane segment VII of the AT1 receptor differentiate between closely related insurmountable and competitive angiotensin antagonists.

scientific article published on October 1994

N-acyl taurines are endogenous lipid messengers that improve glucose homeostasis

scientific article published on 18 November 2019

NK1 Receptor Fused to beta -Arrestin Displays a Single-Component, High-Affinity Molecular Phenotype

scientific article published on 01 July 2002

Natural agonist enhancing bis-His zinc-site in transmembrane segment V of the tachykinin NK3 receptor

scientific article published on 01 November 1998

Nervous control of pancreatic endocrine secretion in pigs. III. The effect of acetylcholine on the pancreatic secretion of insulin and glucagon

scientific article published on 01 January 1981

Neural regulation of pancreatic hormone secretion by the C-terminal tetrapeptide of CCK

scientific article published in Nature

Neuronal activity in human lateral temporal cortex during serial retrieval from short-term memory.

scientific article

Neuropeptide Y in guinea pig, rabbit, rat and man. Identical amino acid sequence and oxidation of methionine-17 ⬇️

scientific article published on April 1, 1988

Neuropeptide Y in the human female genital tract: localization and biological action

scientific article published on 01 August 1989

Neurotensin Is Coexpressed, Coreleased, and Acts Together With GLP-1 and PYY in Enteroendocrine Control of Metabolism

scientific article published on 15 October 2015

No Response of Pancreatic Hormones to Hypoglycemia in Diabetic Autonomic Neuropathy*

article

Non-peptide angiotensin agonist. Functional and molecular interaction with the AT1 receptor.

scientific article published on January 1995

Nonpeptide and peptide growth hormone secretagogues act both as ghrelin receptor agonist and as positive or negative allosteric modulators of ghrelin signaling

scientific article published on 19 May 2005

Novel method for the study of receptor Ca2+ signalling exemplified by the NK1 receptor.

scientific article

Opposite Regulation of Ghrelin and Glucagon-like Peptide-1 by Metabolite G-Protein-Coupled Receptors.

scientific article

Oral 2-oleyl glyceryl ether improves glucose tolerance in mice through the GPR119 receptor.

scientific article published on 14 June 2016

Overlapping binding site for the endogenous agonist, small-molecule agonists, and ago-allosteric modulators on the ghrelin receptor

scientific article

Oxygen supply, oxygen consumption, and endocrine and exocrine secretions of the isolated, perfused, porcine pancreas

scientific article published on 01 May 1980

Oxyntomodulin differentially affects glucagon-like peptide-1 receptor beta-arrestin recruitment and signaling through Galpha(s)

scientific article published on 29 March 2007

PDZ domain-mediated interactions of G protein-coupled receptors with postsynaptic density protein 95: quantitative characterization of interactions

scientific article

Pancreatic polypeptide (PP)

scientific article published on 01 January 1978

Pancreatic polypeptide: a hormone under vagal control.

scientific article published on December 1983

Pancreatic-polypeptide (PP) and endocrine tumours of the pancreas

scientific article published on January 1, 1979

Pancreatic-polypeptide response to food in duodenal-ulcer patients before and after vagotomy ⬇️

scientific article published on May 1976

Partial agonism through a zinc-Ion switch constructed between transmembrane domains III and VII in the tachykinin NK(1) receptor

scientific article published on 01 August 2000

Partial processing of the neuropeptide Y precursor in transfected CHO cells.

scientific article published on February 1990

PheVI:09 (Phe6.44) as a sliding microswitch in seven-transmembrane (7TM) G protein-coupled receptor activation

scientific article published on 7 November 2012

Phorbol esters and SDF-1 induce rapid endocytosis and down modulation of the chemokine receptor CXCR4.

scientific article

Plagiarism of the host immune system: lessons about chemokine immunology from viruses.

scientific article published on December 1997

Plasma pancreatic polypeptide concentrations in acute pancreatitis

scientific article published on 01 June 1980

Polypeptide YY (PYY) and pancreatic polypeptide (PP) in rectal carcinoids. An immunocytochemical study

scientific article published on 01 January 1983

Positive versus negative modulation of different endogenous chemokines for CC-chemokine receptor 1 by small molecule agonists through allosteric versus orthosteric binding

scientific article published on 17 June 2008

Potency of ligands correlates with affinity measured against agonist and inverse agonists but not against neutral ligand in constitutively active chemokine receptor

scientific article published on 01 March 2000

Potent inhibition of HIV-1 infectivity in macrophages and lymphocytes by a novel CCR5 antagonist.

scientific article published on April 1997

Primary structure and conformational analysis of peptide methionine-tyrosine, a peptide related to neuropeptide Y and peptide YY isolated from lamprey intestine

scientific article published on 01 July 1991

Primary structure of glucagon and a partial sequence of oxyntomodulin (glucagon-37) from the guinea pig

scientific article published in August 1985

Principles of agonism: undressing efficacy

scientific article published on 01 November 1998

Processing of pro-CGRP in a rat medullary thyroid carcinoma cell line transfected with protease inhibitors ⬇️

scientific article published on November 1, 1991

Processing of two homologous precursors, pro-neuropeptide Y and pro-pancreatic polypeptide, in transfected cell lines expressing different precursor convertases.

scientific article

Processing or inactivation of antimicrobial peptides

scientific article published in Nature

RESPONSE OF PANCREATIC POLYPEPTIDE TO HYPOGLYCAEMIA IN INSULIN-DEPENDENT DIABETICS WITH AND WITHOUT RESIDUAL β-CELL FUNCTION

scientific article published on 01 January 1983

Radioimmunocytochemistry-a novel immunocytochemical principle

scientific article published on 01 October 1977

Receptor structure-based discovery of non-metabolite agonists for the succinate receptor GPR91.

scientific article published on 30 September 2017

Receptors on phaeochromocytoma cells for two members of the PP-fold family--NPY and PP.

scientific article

Regional distribution of neuropeptide Y and its receptor in the porcine central nervous system.

scientific article

Regional distribution of putative NPY Y1 receptors and neurons expressing Y1 mRNA in forebrain areas of the rat central nervous system.

scientific article published on December 1993

Release of PYY from pig intestinal mucosa; luminal and neural regulation.

scientific article

Research Resource: A Chromogranin A Reporter for Serotonin and Histamine Secreting Enteroendocrine Cells

scientific article published on 9 September 2015

Resequencing of 200 human exomes identifies an excess of low-frequency non-synonymous coding variants

Rhythmic contractions in the renal pelvis correlated to ureteral peristalsis

scientific article published on 01 July 1975

Selective recognition of the membrane-bound CX3C chemokine, fractalkine, by the human cytomegalovirus-encoded broad-spectrum receptor US28

scientific article published on 01 December 1998

Septide and neurokinin A are high-affinity ligands on the NK-1 receptor: evidence from homologous versus heterologous binding analysis.

scientific article published on December 1996

Sequence-specific proton NMR assignments and solution structure of bovine pancreatic polypeptide ⬇️

scientific article published on February 4, 1992

Seven transmembrane G protein-coupled receptor repertoire of gastric ghrelin cells

scientific article published on 04 September 2013

Signal epitopes in the three-dimensional structure of neuropeptide Y. Interaction with Y1, Y2, and pancreatic polypeptide receptors

scientific article published on 01 January 1990

Similar activation of signal transduction pathways by the herpesvirus-encoded chemokine receptors US28 and ORF74.

scientific article published on August 2004

Simultaneous recording of the gastro-entero-pancreatic hormonal peptide response to food in man

scientific article published on 01 August 1980

Single-chain vascular endothelial growth factor variant with antagonist activity

scientific article

Snapshot of a signalling complex

scientific article published in Nature

Somatostatin Cell Processes as Pathways for Paracrine Secretion ⬇️

scientific article published on September 28, 1979

Specific residues at the top of transmembrane segment V and VI of the neurokinin-1 receptor involved in binding of the nonpeptide antagonist CP 96,345 [corrected]

scientific article published on 01 September 1994

Split-receptors in the tachykinin neurokinin-1 system--mutational analysis of intracellular loop 3

scientific article published on 01 January 1998

Steric hindrance mutagenesis versus alanine scan in mapping of ligand binding sites in the tachykinin NK1 receptor.

scientific article

Structural basis for constitutive activity and agonist-induced activation of the enteroendocrine fat sensor GPR119.

scientific article published on December 2014

Structural biology: A moving story of receptors

scientific article published in September 2008

Structural biology: Full monty of family B GPCRs

scientific article published on 01 July 2017

Structure-based discovery of novel US28 small molecule ligands with different modes of action

scientific article published on 29 August 2016

Studies of relationships between variation of the human G protein-coupled receptor 40 Gene and Type 2 diabetes and insulin release.

scientific article published in January 2005

Tachykinin non-peptide antagonists: binding domain and molecular mode of action.

scientific article published on February 1995

The CXC chemokine receptor encoded by herpesvirus saimiri, ECRF3, shows ligand-regulated signaling through Gi, Gq, and G12/13 proteins but constitutive signaling only through Gi and G12/13 proteins

scientific article published on 20 May 2004

The MicroRNA Repertoire in Enteroendocrine Cells: Identification of miR-375 as a Potential Regulator of the Enteroendocrine Lineage

scientific article published on 31 August 2015

The PP-fold solution structure of human polypeptide YY and human PYY3-36 as determined by NMR

scientific article published on 01 July 2006

The adhesion G protein-coupled receptor G2 (ADGRG2/GPR64) constitutively activates SRE and NFκB and is involved in cell adhesion and migration

scientific article published on 27 August 2015

The arginine of the DRY motif in transmembrane segment III functions as a balancing micro-switch in the activation of the β2-adrenergic receptor

scientific article published on 26 July 2012

The carboxyl terminus of human cytomegalovirus-encoded 7 transmembrane receptor US28 camouflages agonism by mediating constitutive endocytosis

scientific article published on 18 March 2003

The chemokine system -- a major regulator of angiogenesis in health and disease

scientific article

The dual nature of the tachykinin NK1 receptor.

scientific article published on October 1997

The effect of antral distension on the endocrine pancreas in man.

scientific article published in January 1980

The effect of gastrin-releasing peptide on the endocrine pancreas

scientific article published on 01 May 1987

The effects of beta-adrenergic receptor blockade on the inhibition of gastric acid secretion, and the release of pancreatic polypeptide by antral distension in healthy subjects

scientific article published on 01 January 1980

The first PP supper--Camelot at Bispebjerg.

scientific article published in January 2001

The human cytomegalovirus US28 protein is located in endocytic vesicles and undergoes constitutive endocytosis and recycling.

scientific article published on June 2001

The human herpes virus 8-encoded chemokine receptor is required for angioproliferation in a murine model of Kaposi's sarcoma

scientific article published in March 2005

The influence of calcium on the basal and acetylcholine-stimulated secretion of pancreatic polypeptide

scientific article published on December 1, 1979

The melanocortin-4 receptor is expressed in enteroendocrine L cells and regulates the release of peptide YY and glucagon-like peptide 1 in vivo

scientific article published on 20 November 2014

The minor binding pocket: a major player in 7TM receptor activation

scientific article published on 25 September 2010

The virus-encoded chemokine vMIP-II inhibits virus-induced Tc1-driven inflammation

scientific article

Transcriptional and Functional Characterization of the G Protein-Coupled Receptor Repertoire of Gastric Somatostatin Cells

scientific article published on 16 July 2015

Truncated glucagon-like peptide I, an insulin-releasing hormone from the distal gut

scientific article published on 01 January 1987

Tumorigenesis induced by the HHV8-encoded chemokine receptor requires ligand modulation of high constitutive activity.

scientific article

Two active molecular phenotypes of the tachykinin NK1 receptor revealed by G-protein fusions and mutagenesis.

scientific article

Two nonpeptide tachykinin antagonists act through epitopes on corresponding segments of the NK1 and NK2 receptors.

scientific article

Tyrosylation and purification of peptides for radioiodination

scientific article published on 01 August 1988

Unique interaction pattern for a functionally biased ghrelin receptor agonist

scientific article published on 14 March 2011

Vagovagal stimulation of pancreatic-polypeptide secretion by graded distention of the gastric fundus and antrum in man

scientific article published on 01 January 1979

Validation of chemokine receptors as drug targets.

scientific article published on September 2000

Viral leads for chemokine-modulatory drugs.

scientific article

Virally encoded chemokines and chemokine receptors in the role of viral infections

scientific article

Y1 and Y2 receptors for neuropeptide Y

scientific article published on 01 March 1989

Y2-type receptors for peptide YY on renal proximal tubular cells in the rabbit

scientific article published on 01 December 1989

[7TM receptors--from the olfactory system and new hormones against HIV infection]

scientific article published on 01 February 1997

[Activation of regulatory peptides by post-translational modifications]

[Circulatory regulation during hypovolemic shock]

scientific article published on 01 September 1986

[Non-peptide antagonists to angiotensin II receptors. A review]

scientific article published on 01 November 1993

[Pro34]neuropeptide Y selectively identifies postjunctional-mediated actions of neuropeptide Y in vivo in rats and dogs

scientific article published in January 1991

[The normal brain: a new knowledge in different fields]

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snRNA-seq reveals a subpopulation of adipocytes that regulates thermogenesis

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β-Cell Specific Overexpression of GPR39 Protects against Streptozotocin-Induced Hyperglycemia

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