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List of works by Thomas S. McCormick

A Liquid Biopsy to Assess Brain Tumor Recurrence: Presence of Circulating Mo-MDSC and CD14+ VNN2+ Myeloid Cells as Biomarkers That Distinguish Brain Metastasis From Radiation Necrosis Following Stereotactic Radiosurgery

scientific article published on 21 August 2020

A Phase I Study Evaluating the Safety, Pharmacokinetics, and Clinical Response of a Human IL-12 p40 Antibody in Subjects with Plaque Psoriasis

scientific article published on 01 December 2004

A phase 1, double-blind, placebo-controlled study evaluating single subcutaneous administrations of a human interleukin-12/23 monoclonal antibody in subjects with plaque psoriasis

scientific article published on 01 May 2007

A second generation fungerp analog SCY-247, shows potent <i>in vitro</i> activity against <i>Candida auris</i> and other clinically relevant fungal isolates

scientific article published on 14 December 2020

A second generation fungerp analog SCY-247, shows potent <i>in vivo</i> activity in a murine model of hematogenously disseminated <i>Candida albicans</i>

scientific article published on 14 December 2020

Activated T cells exhibit increased uptake of silicon phthalocyanine Pc 4 and increased susceptibility to Pc 4-photodynamic therapy-mediated cell death

scientific article published on 10 May 2016

Activation of P2X(7)-mediated apoptosis Inhibits DMBA/TPA-induced formation of skin papillomas and cancer in mice.

scientific article

Alefacept in the treatment of psoriasis

scientific article published on September 2008

Allergens retained in clothing

scientific article published on December 2007

An analysis of gene expression data involving examination of signaling pathways activation reveals new insights into the mechanism of action of minoxidil topical foam in men with androgenetic alopecia.

scientific article

An anti-IL-12p40 antibody down-regulates type 1 cytokines, chemokines, and IL-12/IL-23 in psoriasis

scientific article

Antibody and cytokine levels in humans fed on by the common bedbug, Cimex lectularius L.

scientific article published on 11 January 2017

Apoptosis Mechanisms Related to the Increased Sensitivity of Jurkat T-cells versus A431 Epidermoid Cells to Photodynamic Therapy with the Phthalocyanine Pc 4

Apoptosis mechanisms related to the increased sensitivity of Jurkat T-cells vs A431 epidermoid cells to photodynamic therapy with the phthalocyanine Pc 4.

scientific article published on 23 January 2008

Bcl-2 acts subsequent to and independent of Ca2+ fluxes to inhibit apoptosis in thapsigargin- and glucocorticoid-treated mouse lymphoma cells.

scientific article published on June 1996

Biofilm formation by the fungal pathogen Candida albicans: development, architecture, and drug resistance

scientific article published in September 2001

Case report of individual with cutaneous immunodeficiency and novel 1p36 duplication

scientific article published on 13 January 2016

Cell surface and cytokine phenotypes of skin immunocompetent cells involved in ultraviolet-induced immunosuppression

scientific article published in September 2002

Characterization and partial purification of Candida albicans Secretory IL-12 Inhibitory Factor

scientific article

Chronic Psoriatic Skin Inflammation Leads to Increased Monocyte Adhesion and Aggregation

scientific article published on 29 July 2015

Chronic skin-specific inflammation promotes vascular inflammation and thrombosis

scientific article published on 10 May 2012

Chronic, not acute, skin-specific inflammation promotes thrombosis in psoriasis murine models

scientific article published on 16 December 2015

Combining mechanism-based prediction with patient-based profiling for psoriasis metabolomics biomarker discovery

scientific article

Comparison of epigenetic profiles of human oral epithelial cells from HIV-positive (on HAART) and HIV-negative subjects

scientific article published on 17 May 2013

Conceptual Perspectives: Bacterial Antimicrobial Peptide Induction as a Novel Strategy for Symbiosis with the Human Host.

scientific article published on 26 February 2018

Cutaneous hypersensitivity to Candida albicans in idiopathic vulvodynia

scientific article published on 01 October 2005

Cutaneous hypersensitivity to Malassezia sympodialis and dust mite in adult atopic dermatitis with a textile pattern

scientific article published on 01 February 2006

Cutaneous penetration of the topically applied photosensitizer Pc 4 as detected by intravital 2-photon laser scanning microscopy

scientific article published on 23 February 2012

Depletion of antigen-presenting cells by clodronate liposomes reverses the psoriatic skin phenotype in KC-Tie2 mice ⬇️

scientific article published on April 1, 2011

Development of a Functional Biomarker for Use in Cell-Based Therapy Studies in Seropositive Rheumatoid Arthritis

scientific article published on 29 March 2016

Differential modulation of human beta-defensin-3 expression in human oral epithelial cells by HPV oncoproteins E6 and E7: potential implication in oral cancer

scientific article published on 19 April 2012

Documentation of Efficacy of Drugs Affecting Apoptosis and Other Atheroma-Related Mechanisms

scientific article published in April 1998

Does imiquimod pretreatment optimize 308-nm excimer laser (UVB) therapy in psoriasis patients?

scientific article

Dysfunctional blood and target tissue CD4+CD25high regulatory T cells in psoriasis: mechanism underlying unrestrained pathogenic effector T cell proliferation

scientific article

EXTH-63. A LIQUID BIOPSY TO ASSESS TUMOR RECURRENCE: PRESENCE OF MO-MDSC AND CD14 VNN2 CELLS IN PERIPHERAL BLOOD AS A BIOMARKER TO DISTINGUISH BRAIN METASTASIS (BM) FROM RADIATION NECROSIS AFTER STEREOTACTIC RADIOSURGERY

Effects of a Novel Probiotic Combination on Pathogenic Bacterial-Fungal Polymicrobial Biofilms

scientific article published in 2019

Effects of occlusion on the skin of atopic dermatitis patients

scientific article published on September 1, 2010

Epithelial cell-derived antimicrobial peptides are multifunctional agents that bridge innate and adaptive immunity

scientific article published on October 2010

Evaluation of O6-Benzylguanine-Potentiated Topical Carmustine for Mycosis Fungoides: A Phase 1-2 Clinical Trial

scientific article published on 15 February 2017

Evolution of biologic therapies for the treatment of psoriasis

scientific article published on September 2003

Expanding the List of Dysregulated Immunosuppressive Cells in Psoriasis

scientific article published in September 2016

Expression of Bmi-1 in epidermis enhances cell survival by altering cell cycle regulatory protein expression and inhibiting apoptosis

scientific article published on 12 July 2007

FAD-I, a Fusobacterium nucleatum Cell Wall-Associated Diacylated Lipoprotein That Mediates Human Beta Defensin 2 Induction through Toll-Like Receptor-1/2 (TLR-1/2) and TLR-2/6.

scientific article published on 29 February 2016

Feasibility of carotid artery PET/MRI in psoriasis patients

scientific article published on 20 August 2016

Fusobacterium nucleatum induces premature and term stillbirths in pregnant mice: implication of oral bacteria in preterm birth

scientific article published on April 2004

Fusobacterium nucleatum-associated beta-defensin inducer (FAD-I): identification, isolation, and functional evaluation

scientific article published on 16 September 2010

Gastroesophageal reflux disease-associated esophagitis induces endogenous cytokine production leading to motor abnormalities

scientific article published on 12 October 2006

Glutathione Levels Determine Apoptosis in Macrophages ⬇️

scientific article published on June 18, 1998

Hair follicle stem cell-specific PPARgamma deletion causes scarring alopecia

scientific article published on 4 December 2008

Human Beta Defensins and Cancer: Contradictions and Common Ground

scientific article published on 03 May 2019

Human Immunoglobulin G (IgG) Responses to Cimex lectularius L. Saliva

scientific article published on 09 June 2020

Human papillomavirus oncogenic E6 protein regulates human β-defensin 3 (hBD3) expression via the tumor suppressor protein p53.

scientific article published on 28 March 2016

Human β-defensin 3 peptide is increased and redistributed in Crohn's ileitis

scientific article published on April 2013

Hyper-inflammation and skin destruction mediated by rosiglitazone activation of macrophages in IL-6 deficiency

scientific article published on 3 September 2014

IL-17 in psoriasis: implications for therapy and cardiovascular co-morbidities

scientific article published on 4 April 2013

IL-6 signaling in psoriasis prevents immune suppression by regulatory T cells

scientific article published on 31 July 2009

Increased, but Functionally Impaired, CD14(+) HLA-DR(-/low) Myeloid-Derived Suppressor Cells in Psoriasis: A Mechanism of Dysregulated T Cells

scientific article published on 22 January 2016

Indole-3-acetic acid synthesized through the indole-3-pyruvate pathway promotes Candida tropicalis biofilm formation

scientific article published on 17 December 2020

Induction of Alternative Proinflammatory Cytokines Accounts for Sustained Psoriasiform Skin Inflammation in IL-17C+IL-6KO Mice

scientific article published on 27 October 2016

Infection characteristics of an Ecuadorian Trypanosoma cruzi strain with reduced virulence

scientific article published on February 1995

Inflammatory mediators are perpetuated in macrophages resistant to apoptosis induced by hypoxia ⬇️

scientific article published on December 9, 1997

Inhibition of monocyte-derived dendritic cell differentiation and interleukin-12 production by complement iC3b via a mitogen-activated protein kinase signalling pathway

scientific article published on 01 April 2005

Inhibition of monocytic interleukin-12 production by Candida albicans via selective activation of ERK mitogen-activated protein kinase

scientific article published in May 2004

Interaction of Candida albicans with adherent human peripheral blood mononuclear cells increases C. albicans biofilm formation and results in differential expression of pro- and anti-inflammatory cytokines

scientific article published on 5 March 2007

Interaction of Resistin and Systolic Blood Pressure in Psoriasis Severity

scientific article published on 15 November 2019

Interleukin 6 regulates psoriasiform inflammation-associated thrombosis.

scientific article published on 08 December 2016

Isotype determination of anti-Trypanosoma cruzi antibody in murine Chagas' disease

scientific article published on June 1, 1992

Keratinocyte but not endothelial cell-specific overexpression of Tie2 leads to the development of psoriasis

scientific article

Keratinocyte overexpression of IL-17C promotes psoriasiform skin inflammation

scientific article published on 28 January 2013

Macrophages and cutaneous inflammation

scientific article published on 01 January 2000

Maintenance of calcium homeostasis in the endoplasmic reticulum by Bcl-2

scientific article

Malignant T cells in cutaneous T-cell lymphoma lesions contain decreased levels of the antiapoptotic protein Ku70

scientific article

Modification of surface properties of biomaterials influences the ability of Candida albicans to form biofilms

scientific article published in December 2005

Mouse Lymphoma Cells Destined to Undergo Apoptosis in Response to Thapsigargin Treatment Fail to Generate a Calcium-mediatedgrp78/grp94Stress Response

scientific article published in Journal of Biological Chemistry

Overexpression of AQP3 and AQP10 in the skin exacerbates psoriasiform acanthosis

scientific article published on 23 January 2017

Overexpression of the oncofetal Fn variant containing the EDA splice-in segment in the dermal-epidermal junction of psoriatic uninvolved skin.

scientific article published on April 2000

Phenotypical analysis of ectoenzymes CD39/CD73 and adenosine receptor 2A in CD4+ CD25high Foxp3+ regulatory T-cells in psoriasis

scientific article published on 15 March 2017

Photodynamic therapy with the phthalocyanine photosensitizer Pc 4: the case experience with preclinical mechanistic and early clinical-translational studies

scientific article published on 15 February 2007

Photodynamic therapy with the silicon phthalocyanine pc 4 induces apoptosis in mycosis fungoides and sezary syndrome

scientific article published on 12 December 2010

Physical and mental impact of psoriasis severity as measured by the compact Short Form-12 Health Survey (SF-12) quality of life tool

scientific article published on 29 December 2011

Positive treatment effects of ustekinumab in psoriasis: Analysis of lesional and systemic parameters

scientific article published on 9 April 2010

Prevention of UVB-induced immunosuppression in mice by the green tea polyphenol (-)-epigallocatechin-3-gallate may be associated with alterations in IL-10 and IL-12 production

scientific article published in November 1999

Propensity for macrophage apoptosis is related to the pattern of expression and function of integrin extracellular matrix receptors.

scientific article published on May 1998

Protection from Psoriasis-Related Thrombosis after Inhibition of IL-23 or IL-17A.

scientific article published on 23 September 2017

Proteomic and bioinformatic profile of primary human oral epithelial cells

scientific article published on 16 October 2012

Proteomic signatures of human oral epithelial cells in HIV-infected subjects

scientific article

Proteomics of skin proteins in psoriasis: from discovery and verification in a mouse model to confirmation in humans

scientific article published on 28 October 2014

Psoriasis and Psoriatic Arthritis Cardiovascular Disease Endotypes Identified by Red Blood Cell Distribution Width and Mean Platelet Volume

scientific article published on 09 January 2020

Psoriasis and cardiovascular risk factors: increased serum myeloperoxidase and corresponding immunocellular overexpression by Cd11b(+) CD68(+) macrophages in skin lesions

scientific article published on December 2013

Psoriasis patients exhibit impairment of the high potency CCR5(+) T regulatory cell subset

scientific article published on 06 July 2013

Quantification of Human -Defensin-2 and -3 in Body Fluids: Application for Studies of Innate Immunity

scientific article published on 22 February 2007

Recombinant human granulocyte macrophage-colony stimulating factor expressed in yeast (sargramostim): A potential ally to combat serious infections

scientific article published on 30 October 2019

Regulation generation: the suppressive functions of human regulatory T cells

scientific article

Severe dermatomyositis triggered by interferon beta-1a therapy and associated with enhanced type I interferon signaling

scientific article published on October 2008

Signal peptide cleavage is essential for surface expression of a regulatory T cell surface protein, leucine rich repeat containing 32 (LRRC32).

scientific article published on 26 May 2011

Single administration of lesion-limited high-dose (TURBO) ultraviolet B using the excimer laser: clinical clearing in association with apoptosis of epidermal and dermal T cell subsets in psoriasis

scientific article published in December 2012

Skin-infiltrating monocytes/macrophages migrate to draining lymph nodes and produce IL-10 after contact sensitizer exposure to UV-irradiated skin

scientific article published on 29 May 2008

Stat3 phosphorylation mediates resistance of primary human T cells to regulatory T cell suppression

scientific article published on 9 February 2011

Successful cutaneous delivery of the photosensitizer silicon phthalocyanine 4 for photodynamic therapy ⬇️

scientific article published on May 30, 2011

Successful liver transplantation in short telomere syndromes without bone marrow failure due to DKC1 mutation

scientific article published on 12 March 2020

Systemic contact dermatitis from propylene glycol.

scientific article published in March 2008

The Response of microRNAs to Solar UVR in Skin-Resident Melanocytes Differs between Melanoma Patients and Healthy Persons

scientific article

The dark side of regulatory T cells in psoriasis

scientific article published in September 2011

The key role of aquaporin 3 and aquaporin 10 in the pathogenesis of pompholyx

scientific article

The ratio of HLA-DR and VNN2+ expression on CD14+ myeloid derived suppressor cells can distinguish glioblastoma from radiation necrosis patients

scientific article published on 27 May 2017

The yin and yang of human Beta-defensins in health and disease

scientific article published on 8 October 2012

Topical delivery of a preformed photosensitizer for photodynamic therapy of cutaneous lesions

scientific article published on 13 February 2012

Transgenic overexpression of keratinocyte-specific VEGF and Ang1 in combination promotes wound healing under nondiabetic but not diabetic conditions ⬇️

scientific article published on January 1, 2012

Trypanosoma cruzi: cross-reactive anti-heart autoantibodies produced during infection in mice

scientific article

Using chimeric antigen receptor T-cell therapy to fight glioblastoma multiforme: past, present and future developments

scientific article

Visualization of atherosclerosis as detected by coronary artery calcium and carotid intima-media thickness reveals significant atherosclerosis in a cross-sectional study of psoriasis patients in a tertiary care center

scientific article published on 22 July 2016

iC3b arrests monocytic cell differentiation into CD1c-expressing dendritic cell precursors: a mechanism for transiently decreased dendritic cells in vivo after human skin injury by ultraviolet B.

scientific article published in May 2003

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