List of works - Matthew R. Allen

Absence of exposed bone following dental extraction in beagle dogs treated with 9 months of high-dose zoledronic acid combined with dexamethasone

scientific article published on February 2013

Aging and estrogen status: a possible endothelium-dependent vascular coupling mechanism in bone remodeling.

scientific article

Alendronate reduces bone toughness of ribs without significantly increasing microdamage accumulation in dogs following 3 years of daily treatment.

scientific article published on 08 May 2008

Alendronate treatment results in similar levels of trabecular bone remodeling in the femoral neck and vertebra.

scientific article published on 21 August 2008

Alterations in canine vertebral bone turnover, microdamage accumulation, and biomechanical properties following 1-year treatment with clinical treatment doses of risedronate or alendronate.

scientific article published on 12 June 2006

Antiremodeling Agents Influence Osteoblast Activity Differently in Modeling and Remodeling Sites of Canine Rib

scientific article published in October 2006

Assessing the inter- and intra-animal variability of in vivo OsteoProbe skeletal measures in untreated dogs.

scientific article published on 08 August 2016

Biglycan deficiency interferes with ovariectomy-induced bone loss.

scientific article

Biglycan-deficient mice have delayed osteogenesis after marrow ablation.

scientific article published on 6 May 2003

Bisphosphonate binding affinity affects drug distribution in both intracortical and trabecular bone of rabbits.

scientific article published on 17 January 2012

Bisphosphonate effects on bone turnover, microdamage, and mechanical properties: what we think we know and what we know that we don't know.

scientific article published on 16 October 2010

Bisphosphonate treatment modifies canine bone mineral and matrix properties and their heterogeneity.

scientific article

Bisphosphonates alter trabecular bone collagen cross-linking and isomerization in beagle dog vertebra.

scientific article

Bisphosphonates and osteonecrosis of the jaw: moving from the bedside to the bench.

scientific article

Bisphosphonates do not alter the rate of secondary mineralization.

scientific article

Can deterministic mechanical size effects contribute to fracture and microdamage accumulation in trabecular bone?

scientific article

Cancer treatment dosing regimens of zoledronic acid result in near-complete suppression of mandible intracortical bone remodeling in beagle dogs

scientific article

Cell autonomous requirement of connexin 43 for osteocyte survival: consequences for endocortical resorption and periosteal bone formation.

scientific article published on February 2012

Changes in non-enzymatic glycation and its association with altered mechanical properties following 1-year treatment with risedronate or alendronate.

scientific article published on 11 October 2008

Changes in vertebral strength-density and energy absorption-density relationships following bisphosphonate treatment in beagle dogs

scientific article published on 21 August 2007

Compromised osseous healing of dental extraction sites in zoledronic acid-treated dogs.

scientific article

Control of bone mass and remodeling by PTH receptor signaling in osteocytes

scientific article

Dietary phosphate restriction normalizes biochemical and skeletal abnormalities in a murine model of tumoral calcinosis

scientific article published on 18 October 2011

Differential skeletal responses of hindlimb unloaded rats on a vitamin D-deficient diet to 1,25-dihydroxyvitamin D3 and its analog, seocalcitol (EB1089).

scientific article

Effects of combination treatment with alendronate and raloxifene on skeletal properties in a beagle dog model

scientific article published on 09 August 2017

Effects of eccentric exercise training on cortical bone and muscle strength in the estrogen-deficient mouse

scientific article published on 13 January 2005

Effects of suppression of bone turnover on cortical and trabecular load sharing in the canine vertebral body.

scientific article

Exercise-induced changes in the cortical bone of growing mice are bone- and gender-specific

scientific article published on 19 January 2007

Food restriction and simulated microgravity: effects on bone and serum leptin.

scientific article published on 14 February 2008

Functional recovery of the plantarflexor muscle group after hindlimb unloading in the rat.

scientific article

Greater magnitude of turnover suppression occurs earlier after treatment initiation with risedronate than alendronate.

scientific article published on 15 July 2010

Heritability of lumbar trabecular bone mechanical properties in baboons.

scientific article

Higher bone matrix density exists in only a subset of patients with bisphosphonate-related osteonecrosis of the jaw.

scientific article

In vivo effects of zoledronic acid on oral mucosal epithelial cells

scientific article

Increased nitric oxide-mediated vasodilation of bone resistance arteries is associated with increased trabecular bone volume after endurance training in rats.

scientific article

Increased strontium uptake in trabecular bone of ovariectomized calcium-deficient rats treated with strontium ranelate or strontium chloride

scientific article published on 15 September 2011

Iron deficiency drives an autosomal dominant hypophosphatemic rickets (ADHR) phenotype in fibroblast growth factor-23 (Fgf23) knock-in mice.

scientific article published on 17 October 2011

Lack of Correlation Between Duration of Osteonecrosis of the Jaw and Sequestra Tissue Morphology: What It Tells Us About the Condition and What It Means for Future Studies ⬇️

scientific article published on November 1, 2010

Low bone turnover and microdamage? How and where to assess it?

scientific article published on 01 July 2008

Mandible matrix necrosis in beagle dogs after 3 years of daily oral bisphosphonate treatment.

scientific article published on May 2008

Mandibular necrosis in beagle dogs treated with bisphosphonates.

scientific article published on August 2009

Mechanics of linear microcracking in trabecular bone

scientific article published on 16 November 2018

Methodological assessment of acid-etching for visualizing the osteocyte lacunar-canalicular networks using scanning electron microscopy

scientific article published on 01 March 2010

Microcrack density and nanomechanical properties in the subchondral region of the immature piglet femoral head following ischemic osteonecrosis.

scientific article published on 3 August 2012

N-acetylcysteine (NAC), an anti-oxidant, does not improve bone mechanical properties in a rat model of progressive chronic kidney disease-mineral bone disorder

scientific article published on 23 March 2020

One year of alendronate treatment lowers microstructural stresses associated with trabecular microdamage initiation.

scientific article

Orthodontic mini-implant diameter does not affect in-situ linear microcrack generation in the mandible or the maxilla

scientific article published on 01 December 2012

Ovariectomy stimulates and bisphosphonates inhibit intracortical remodeling in the mouse mandible.

scientific article

PTH receptor signaling in osteocytes governs periosteal bone formation and intracortical remodeling.

scientific article

Parathyroid suppression therapy normalizes chronic kidney disease-induced elevations in cortical bone vascular perfusion: a pilot study

scientific article published on 08 May 2019

Periosteum: biology, regulation, and response to osteoporosis therapies.

scientific article

Raloxifene enhances material-level mechanical properties of femoral cortical and trabecular bone

scientific article published on 3 May 2007

Raloxifene reduces skeletal fractures in an animal model of osteogenesis imperfecta

scientific article published on 18 December 2015

Reference point indentation is insufficient for detecting alterations in traditional mechanical properties of bone under common experimental conditions

scientific article published on 9 April 2016

Reply to: fatigue in bone: a novel phenomenon attributable to bisphosphonate use

scientific article published on 04 May 2010

Reversal of loss of bone mass in old mice treated with mefloquine

Site- and compartment-specific changes in bone with hindlimb unloading in mature adult rats.

scientific article published in July 2002

Skeletal accumulation of bisphosphonates: implications for osteoporosis treatment

scientific article published on 01 November 2008

Skeletal accumulation of fluorescently tagged zoledronate is higher in animals with early stage chronic kidney disease

scientific article published on 11 June 2018

Skeletal effects of zoledronic acid in an animal model of chronic kidney disease

scientific article

Skeletal vascular perfusion is altered in chronic kidney disease.

scientific article

Sost downregulation and local Wnt signaling are required for the osteogenic response to mechanical loading.

scientific article published on 30 October 2011

Strontium ranelate does not stimulate bone formation in ovariectomized rats.

scientific article published on 3 April 2008

Studying the role of microcracks in the pathophysiology of BRONJ

scientific article published on 18 August 2009

The effects of bisphosphonates on jaw bone remodeling, tissue properties, and extraction healing.

scientific article published on 27 January 2011

The mechanical phenotype of biglycan-deficient mice is bone- and gender-specific

scientific article published on 9 March 2006

The pathogenesis of bisphosphonate-related osteonecrosis of the jaw: so many hypotheses, so few data

scientific article

Three years of alendronate treatment does not continue to decrease microstructural stresses and strains associated with trabecular microdamage initiation beyond those at 1 year.

scientific article published on 12 January 2012

Three years of alendronate treatment results in similar levels of vertebral microdamage as after one year of treatment

scientific article published in November 2007

Time course of rapid bone loss and cortical porosity formation observed by longitudinal μCT in a rat model of CKD

scientific article published on 03 May 2019

List of works by Matthew R. Allen

Absence of exposed bone following dental extraction in beagle dogs treated with 9 months of high-dose zoledronic acid combined with dexamethasone

Aging and estrogen status: a possible endothelium-dependent vascular coupling mechanism in bone remodeling.

Alendronate reduces bone toughness of ribs without significantly increasing microdamage accumulation in dogs following 3 years of daily treatment.

Alendronate treatment results in similar levels of trabecular bone remodeling in the femoral neck and vertebra.

Alterations in canine vertebral bone turnover, microdamage accumulation, and biomechanical properties following 1-year treatment with clinical treatment doses of risedronate or alendronate.

Antiremodeling Agents Influence Osteoblast Activity Differently in Modeling and Remodeling Sites of Canine Rib

Assessing the inter- and intra-animal variability of in vivo OsteoProbe skeletal measures in untreated dogs.

Biglycan deficiency interferes with ovariectomy-induced bone loss.

Biglycan-deficient mice have delayed osteogenesis after marrow ablation.

Bisphosphonate binding affinity affects drug distribution in both intracortical and trabecular bone of rabbits.

Bisphosphonate effects on bone turnover, microdamage, and mechanical properties: what we think we know and what we know that we don't know.

Bisphosphonate treatment modifies canine bone mineral and matrix properties and their heterogeneity.

Bisphosphonates alter trabecular bone collagen cross-linking and isomerization in beagle dog vertebra.

Bisphosphonates and osteonecrosis of the jaw: moving from the bedside to the bench.

Bisphosphonates do not alter the rate of secondary mineralization.

Can deterministic mechanical size effects contribute to fracture and microdamage accumulation in trabecular bone?

Cancer treatment dosing regimens of zoledronic acid result in near-complete suppression of mandible intracortical bone remodeling in beagle dogs

Cell autonomous requirement of connexin 43 for osteocyte survival: consequences for endocortical resorption and periosteal bone formation.

Changes in non-enzymatic glycation and its association with altered mechanical properties following 1-year treatment with risedronate or alendronate.

Changes in vertebral strength-density and energy absorption-density relationships following bisphosphonate treatment in beagle dogs

Compromised osseous healing of dental extraction sites in zoledronic acid-treated dogs.

Control of bone mass and remodeling by PTH receptor signaling in osteocytes

Dietary phosphate restriction normalizes biochemical and skeletal abnormalities in a murine model of tumoral calcinosis

Differential skeletal responses of hindlimb unloaded rats on a vitamin D-deficient diet to 1,25-dihydroxyvitamin D3 and its analog, seocalcitol (EB1089).

Effects of combination treatment with alendronate and raloxifene on skeletal properties in a beagle dog model

Effects of eccentric exercise training on cortical bone and muscle strength in the estrogen-deficient mouse

Effects of suppression of bone turnover on cortical and trabecular load sharing in the canine vertebral body.

Exercise-induced changes in the cortical bone of growing mice are bone- and gender-specific

Food restriction and simulated microgravity: effects on bone and serum leptin.

Functional recovery of the plantarflexor muscle group after hindlimb unloading in the rat.

Greater magnitude of turnover suppression occurs earlier after treatment initiation with risedronate than alendronate.

Heritability of lumbar trabecular bone mechanical properties in baboons.

Higher bone matrix density exists in only a subset of patients with bisphosphonate-related osteonecrosis of the jaw.

In vivo effects of zoledronic acid on oral mucosal epithelial cells

Increased nitric oxide-mediated vasodilation of bone resistance arteries is associated with increased trabecular bone volume after endurance training in rats.

Increased strontium uptake in trabecular bone of ovariectomized calcium-deficient rats treated with strontium ranelate or strontium chloride

Iron deficiency drives an autosomal dominant hypophosphatemic rickets (ADHR) phenotype in fibroblast growth factor-23 (Fgf23) knock-in mice.

Lack of Correlation Between Duration of Osteonecrosis of the Jaw and Sequestra Tissue Morphology: What It Tells Us About the Condition and What It Means for Future Studies ⬇️

Low bone turnover and microdamage? How and where to assess it?

Mandible matrix necrosis in beagle dogs after 3 years of daily oral bisphosphonate treatment.

Mandibular necrosis in beagle dogs treated with bisphosphonates.

Mechanics of linear microcracking in trabecular bone

Methodological assessment of acid-etching for visualizing the osteocyte lacunar-canalicular networks using scanning electron microscopy

Microcrack density and nanomechanical properties in the subchondral region of the immature piglet femoral head following ischemic osteonecrosis.

N-acetylcysteine (NAC), an anti-oxidant, does not improve bone mechanical properties in a rat model of progressive chronic kidney disease-mineral bone disorder

One year of alendronate treatment lowers microstructural stresses associated with trabecular microdamage initiation.

Orthodontic mini-implant diameter does not affect in-situ linear microcrack generation in the mandible or the maxilla

Ovariectomy stimulates and bisphosphonates inhibit intracortical remodeling in the mouse mandible.

PTH receptor signaling in osteocytes governs periosteal bone formation and intracortical remodeling.

Parathyroid suppression therapy normalizes chronic kidney disease-induced elevations in cortical bone vascular perfusion: a pilot study

Periosteum: biology, regulation, and response to osteoporosis therapies.

Raloxifene enhances material-level mechanical properties of femoral cortical and trabecular bone

Raloxifene reduces skeletal fractures in an animal model of osteogenesis imperfecta

Reference point indentation is insufficient for detecting alterations in traditional mechanical properties of bone under common experimental conditions

Reply to: fatigue in bone: a novel phenomenon attributable to bisphosphonate use

Reversal of loss of bone mass in old mice treated with mefloquine

Site- and compartment-specific changes in bone with hindlimb unloading in mature adult rats.

Skeletal accumulation of bisphosphonates: implications for osteoporosis treatment

Skeletal accumulation of fluorescently tagged zoledronate is higher in animals with early stage chronic kidney disease

Skeletal effects of zoledronic acid in an animal model of chronic kidney disease

Skeletal vascular perfusion is altered in chronic kidney disease.

Sost downregulation and local Wnt signaling are required for the osteogenic response to mechanical loading.

Strontium ranelate does not stimulate bone formation in ovariectomized rats.

Studying the role of microcracks in the pathophysiology of BRONJ

The effects of bisphosphonates on jaw bone remodeling, tissue properties, and extraction healing.

The mechanical phenotype of biglycan-deficient mice is bone- and gender-specific

The pathogenesis of bisphosphonate-related osteonecrosis of the jaw: so many hypotheses, so few data

Three years of alendronate treatment does not continue to decrease microstructural stresses and strains associated with trabecular microdamage initiation beyond those at 1 year.

Three years of alendronate treatment results in similar levels of vertebral microdamage as after one year of treatment

Time course of rapid bone loss and cortical porosity formation observed by longitudinal μCT in a rat model of CKD