List of works - David A. Simpson

A Multi-Omics Approach Identifies Key Regulatory Pathways Induced by Long-Term Zinc Supplementation in Human Primary Retinal Pigment Epithelium

scientific article published on 06 October 2020

A comparison of RNA extraction and sequencing protocols for detection of small RNAs in plasma.

scientific article published on 3 June 2019

Characterisation of the advanced glycation endproduct receptor complex in the retinal pigment epithelium

scientific article

Considerations for optimization of microRNA PCR assays for molecular diagnosis.

scientific article published on 8 February 2016

Deep sequencing reveals predominant expression of miR-21 amongst the small non-coding RNAs in retinal microvascular endothelial cells.

scientific article

Development of a diagnostic genetic test for simplex and autosomal recessive retinitis pigmentosa

scientific article published on 29 June 2010

Diabetes downregulates large-conductance Ca2+-activated potassium beta 1 channel subunit in retinal arteriolar smooth muscle

scientific article published on 09 February 2007

Differential Expression of Urinary Exosomal MicroRNAs miR-21-5p and miR-30b-5p in Individuals with Diabetic Kidney Disease

scientific article published on 29 July 2019

Distinctive profile of IsomiR expression and novel microRNAs in rat heart left ventricle

scientific article

Enrichment of pathogenic alleles in the brittle cornea gene, ZNF469, in keratoconus ⬇️

scientific article published on 3 June 2014

Ex vivo expansion of human outgrowth endothelial cells leads to IL-8-mediated replicative senescence and impaired vasoreparative function.

scientific article published in August 2013

Expression of the 67 kDa laminin receptor (67LR) during retinal development: correlations with angiogenesis.

scientific article

Expression of the VEGF gene family during retinal vaso-obliteration and hypoxia

scientific article published on 01 August 1999

Expression of vascular endothelial growth factor (VEGF) and its receptors is regulated in eyes with intra-ocular tumours

article by Alan W Stitt et al published 1 November 1998 in Journal of Pathology

Individual mRNA expression profiles reveal the effects of specific microRNAs.

scientific article published on 16 May 2008

Kinematics and timing of Tertiary extension in the western Lake Mead region, Nevada

scholarly article

Kinematics and timing of Tertiary extension in the western Lake Mead region, Nevada: Reply

scholarly article

Kv1.5 is a major component underlying the A-type potassium current in retinal arteriolar smooth muscle.

scientific article published on 13 October 2006

Machine learning approaches to supporting the identification of photoreceptor-enriched genes based on expression data

scientific article

MicroRNA-155 promotes resolution of hypoxia-inducible factor 1alpha activity during prolonged hypoxia

scientific article published on August 2011

MicroRNA-containing extracellular vesicles released from endothelial colony-forming cells modulate angiogenesis during ischaemic retinopathy.

scientific article published on 20 June 2017

Mini-XT, a miniaturized tagmentation-based protocol for efficient sequencing of SARS-CoV-2

scientific article published on 03 March 2022

Molecular analysis of endothelial progenitor cell (EPC) subtypes reveals two distinct cell populations with different identities.

scientific article

Molecular diagnosis for heterogeneous genetic diseases with targeted high-throughput DNA sequencing applied to retinitis pigmentosa.

scientific article

Mutation altering the miR-184 seed region causes familial keratoconus with cataract

scientific article

Mutational Analysis of the Rhodopsin Gene in Sector Retinitis Pigmentosa.

scientific article published on 29 September 2014

Mutational analysis of MIR184 in sporadic keratoconus and myopia

scientific article published on 5 August 2013

Mutational spectrum of the ZEB1 gene in corneal dystrophies supports a genotype-phenotype correlation.

scientific article published on 3 May 2013

Next generation sequencing-based molecular diagnosis of retinitis pigmentosa: identification of a novel genotype-phenotype correlation and clinical refinements

scientific article published on 24 October 2013

Next-generation sequencing-based molecular diagnosis of 82 retinitis pigmentosa probands from Northern Ireland

scientific article

Prediction and verification of miRNA expression in human and rat retinas.

scientific article

Prediction of microRNAs affecting mRNA expression during retinal development

scientific article

RNA-Sequencing data supports the existence of novel VEGFA splicing events but not of VEGFAxxxb isoforms

scientific article

Rapid quantification of microRNAs in plasma using a fast real-time PCR system.

scientific article published in May 2015

Retinopathy is reduced during experimental diabetes in a mouse model of outer retinal degeneration.

scientific article

Rod photoreceptor loss in Rho-/- mice reduces retinal hypoxia and hypoxia-regulated gene expression.

scientific article

Role of vascular endothelial growth factor and placental growth factors during retinal vascular development and hyaloid regression.

scientific article

Selective extracellular vesicle-mediated export of an overlapping set of microRNAs from multiple cell types.

scientific article

Small RNAs from plants, bacteria and fungi within the order Hypocreales are ubiquitous in human plasma

scientific article

TRPV2 Channels Contribute to Stretch-Activated Cation Currents and Myogenic Constriction in Retinal Arterioles.

scientific article published in October 2016

VEGF-induced retinal angiogenic signaling is critically dependent on Ca²⁺ signaling by Ca²⁺/calmodulin-dependent protein kinase II.

scientific article

Whole-mitochondrial genome sequencing in primary open-angle glaucoma using massively parallel sequencing identifies novel and known pathogenic variants.

scientific article published on 18 September 2014

List of works by David A. Simpson

A Multi-Omics Approach Identifies Key Regulatory Pathways Induced by Long-Term Zinc Supplementation in Human Primary Retinal Pigment Epithelium

A comparison of RNA extraction and sequencing protocols for detection of small RNAs in plasma.

Characterisation of the advanced glycation endproduct receptor complex in the retinal pigment epithelium

Considerations for optimization of microRNA PCR assays for molecular diagnosis.

Deep sequencing reveals predominant expression of miR-21 amongst the small non-coding RNAs in retinal microvascular endothelial cells.

Development of a diagnostic genetic test for simplex and autosomal recessive retinitis pigmentosa

Diabetes downregulates large-conductance Ca2+-activated potassium beta 1 channel subunit in retinal arteriolar smooth muscle

Differential Expression of Urinary Exosomal MicroRNAs miR-21-5p and miR-30b-5p in Individuals with Diabetic Kidney Disease

Distinctive profile of IsomiR expression and novel microRNAs in rat heart left ventricle

Enrichment of pathogenic alleles in the brittle cornea gene, ZNF469, in keratoconus ⬇️

Ex vivo expansion of human outgrowth endothelial cells leads to IL-8-mediated replicative senescence and impaired vasoreparative function.

Expression of the 67 kDa laminin receptor (67LR) during retinal development: correlations with angiogenesis.

Expression of the VEGF gene family during retinal vaso-obliteration and hypoxia

Expression of vascular endothelial growth factor (VEGF) and its receptors is regulated in eyes with intra-ocular tumours

Individual mRNA expression profiles reveal the effects of specific microRNAs.

Kinematics and timing of Tertiary extension in the western Lake Mead region, Nevada

Kinematics and timing of Tertiary extension in the western Lake Mead region, Nevada: Reply

Kv1.5 is a major component underlying the A-type potassium current in retinal arteriolar smooth muscle.

Machine learning approaches to supporting the identification of photoreceptor-enriched genes based on expression data

MicroRNA-155 promotes resolution of hypoxia-inducible factor 1alpha activity during prolonged hypoxia

MicroRNA-containing extracellular vesicles released from endothelial colony-forming cells modulate angiogenesis during ischaemic retinopathy.

Mini-XT, a miniaturized tagmentation-based protocol for efficient sequencing of SARS-CoV-2

Molecular analysis of endothelial progenitor cell (EPC) subtypes reveals two distinct cell populations with different identities.

Molecular diagnosis for heterogeneous genetic diseases with targeted high-throughput DNA sequencing applied to retinitis pigmentosa.

Mutation altering the miR-184 seed region causes familial keratoconus with cataract

Mutational Analysis of the Rhodopsin Gene in Sector Retinitis Pigmentosa.

Mutational analysis of MIR184 in sporadic keratoconus and myopia

Mutational spectrum of the ZEB1 gene in corneal dystrophies supports a genotype-phenotype correlation.

Next generation sequencing-based molecular diagnosis of retinitis pigmentosa: identification of a novel genotype-phenotype correlation and clinical refinements

Next-generation sequencing-based molecular diagnosis of 82 retinitis pigmentosa probands from Northern Ireland

Prediction and verification of miRNA expression in human and rat retinas.

Prediction of microRNAs affecting mRNA expression during retinal development

RNA-Sequencing data supports the existence of novel VEGFA splicing events but not of VEGFAxxxb isoforms

Rapid quantification of microRNAs in plasma using a fast real-time PCR system.

Retinopathy is reduced during experimental diabetes in a mouse model of outer retinal degeneration.

Rod photoreceptor loss in Rho-/- mice reduces retinal hypoxia and hypoxia-regulated gene expression.

Role of vascular endothelial growth factor and placental growth factors during retinal vascular development and hyaloid regression.

Selective extracellular vesicle-mediated export of an overlapping set of microRNAs from multiple cell types.

Small RNAs from plants, bacteria and fungi within the order Hypocreales are ubiquitous in human plasma

TRPV2 Channels Contribute to Stretch-Activated Cation Currents and Myogenic Constriction in Retinal Arterioles.

VEGF-induced retinal angiogenic signaling is critically dependent on Ca²⁺ signaling by Ca²⁺/calmodulin-dependent protein kinase II.

Whole-mitochondrial genome sequencing in primary open-angle glaucoma using massively parallel sequencing identifies novel and known pathogenic variants.