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List of works by Timothy J McDonald

A Type 1 Diabetes Genetic Risk Score Can Aid Discrimination Between Type 1 and Type 2 Diabetes in Young Adults

scientific article published on 17 November 2015

A Type 1 Diabetes Genetic Risk Score Can Identify Patients With GAD65 Autoantibody-Positive Type 2 Diabetes Who Rapidly Progress to Insulin Therapy

scientific article published on 23 October 2018

A cautionary tale: Unforeseen consequences of lean processing in a blood sciences laboratory

scientific article

A high-sensitivity electrochemiluminescence-based ELISA for the measurement of the oxidative stress biomarker, 3-nitrotyrosine, in human blood serum and cells.

scientific article published on 16 March 2018

A novel case of a raised testosterone and LH in a young man

scientific article published on 12 July 2011

A type 1 diabetes genetic risk score can discriminate monogenic autoimmunity with diabetes from early-onset clustering of polygenic autoimmunity with diabetes.

scientific article published on 7 February 2018

Activating germline mutations in STAT3 cause early-onset multi-organ autoimmune disease

scientific article

Assessment of endogenous insulin secretion in insulin treated diabetes predicts postprandial glucose and treatment response to prandial insulin

scientific article

Beta cell function and ongoing autoimmunity in long-standing, childhood onset type 1 diabetes

scientific article published on 3 September 2016

C-Peptide Decline in Type 1 Diabetes Has Two Phases: An Initial Exponential Fall and a Subsequent Stable Phase.

scientific article

Clinical Impact of Residual C-Peptide Secretion in Type 1 Diabetes on Glycemia and Microvascular Complications

scientific article published on 10 December 2020

Comment on: "Dulaglutide treatment results in effective glycaemic control in latent autoimmune diabetes in adults (LADA): A post-hoc analysis of the AWARD-2, -4 and -5 trials"

scientific article published on 17 April 2018

Commercial insulin immunoassays fail to detect commonly prescribed insulin analogues

scientific article published on 11 July 2015

Current laboratory requirements for adrenocorticotropic hormone and renin/aldosterone sample handling are unnecessarily restrictive.

scientific article published in February 2017

Detection of C-Peptide in Urine as a Measure of Ongoing Beta Cell Function

scientific article published on 16 April 2016

Diagnostic confusion? Repeat HbA1c for the diagnosis of diabetes

scientific article published on 01 June 2014

Discovery of biomarkers for glycaemic deterioration before and after the onset of type 2 diabetes: an overview of the data from the epidemiological studies within the IMI DIRECT Consortium

EDTA improves stability of whole blood C-peptide and insulin to over 24 hours at room temperature

scientific article

Effect of the Holiday Season in Patients With Diabetes: Glycemia and Lipids Increase Postholiday, but the Effect Is Small and Transient

scientific article published on 01 January 2014

Effects of surfactant and boron doping on the BWF feature in the Raman spectrum of single-wall carbon nanotube aqueous dispersions

scientific article published on 01 December 2006

Erratum to: The majority of patients with long-duration type 1 diabetes are insulin microsecretors and have functioning beta cells.

scientific article

Exocrine pancreatic dysfunction is common in hepatocyte nuclear factor 1β-associated renal disease and can be symptomatic

scientific article published on 30 January 2018

Faecal calprotectin effectively excludes inflammatory bowel disease in 789 symptomatic young adults with/without alarm symptoms: a prospective UK primary care cohort study

scientific article published on 05 March 2018

Fetal macrosomia and neonatal hyperinsulinemic hypoglycemia associated with transplacental transfer of sulfonylurea in a mother with KCNJ11-related neonatal diabetes.

scientific article

Home Urine C-Peptide Creatinine Ratio Can Be Used to Monitor Islet Transplant Function: Figure 1

scientific article published on 12 March 2014

Home urine C-peptide creatinine ratio (UCPCR) testing can identify type 2 and MODY in pediatric diabetes.

scientific article published on 4 January 2013

Hypoglycaemia following diabetes remission in patients with 6q24 methylation defects: expanding the clinical phenotype.

scientific article published on 31 October 2012

Infliximab and adalimumab are stable in whole blood clotted samples for seven days at room temperature.

scientific article published on 16 March 2015

Interleukin-1 antagonism in type 1 diabetes of long duration

scientific article published on 5 October 2016

Investigating hyperkalaemia in adults

scientific article

Investigating hypokalaemia

scientific article published on 24 September 2013

Islet autoantibodies can discriminate maturity-onset diabetes of the young (MODY) from Type 1 diabetes

scientific article published on 01 September 2011

Lipoprotein composition in HNF1A-MODY: differentiating between HNF1A-MODY and type 2 diabetes

scientific article published on 14 February 2012

Low IgE Is a Useful Tool to Identify STAT3 Gain-of-Function Mutations

scientific article published on 08 September 2016

Markers of β-Cell Failure Predict Poor Glycemic Response to GLP-1 Receptor Agonist Therapy in Type 2 Diabetes

scientific article published on 04 August 2015

Most people with long-duration type 1 diabetes in a large population-based study are insulin microsecretors

scientific article published on 17 December 2014

Persistent C-peptide is associated with reduced hypoglycaemia but not HbA1c in adults with longstanding Type 1 diabetes: evidence for lack of intensive treatment in UK clinical practice?

scientific article published on 27 June 2019

Population-Based Assessment of a Biomarker-Based Screening Pathway to Aid Diagnosis of Monogenic Diabetes in Young-Onset Patients

scientific article published on 12 July 2017

Postexercise Glycemic Control in Type 1 Diabetes Is Associated With Residual β-Cell Function

scientific article published on 03 August 2020

Precision Medicine in Type 2 Diabetes: Clinical Markers of Insulin Resistance Are Associated With Altered Short- and Long-Term Glycemic Response to DPP-4 Inhibitor Therapy.

scientific article published on 31 January 2018

Predictors of Recurrent Severe Hypoglycemia in Adults With Type 1 Diabetes and Impaired Awareness of Hypoglycemia During the HypoCOMPaSS Study

scientific article published on 04 September 2019

Primary care faecal calprotectin testing in children with suspected inflammatory bowel disease: a diagnostic accuracy study

scientific article published on 18 May 2020

Processes Underlying Glycemic Deterioration in Type 2 Diabetes: An IMI DIRECT Study

scientific article published on 15 December 2020

Proinsulin is stable at room temperature for 24 hours in EDTA: A clinical laboratory analysis (adAPT 3)

scientific article

Protonation effects on the branching ratio in photoexcited single-walled carbon nanotube dispersions.

scientific article published on 5 March 2008

Random non-fasting C-peptide testing can identify patients with insulin-treated type 2 diabetes at high risk of hypoglycaemia

scientific article

Random non-fasting C-peptide: bringing robust assessment of endogenous insulin secretion to the clinic.

scientific article

Response to Comment on: McDonald et al. High-Sensitivity CRP Discriminates HNF1A-MODY From Other Subtypes of Diabetes. Diabetes Care 2011;34:1860–1862.

scientific article published on 14 November 2011

Screening for neonatal diabetes at day 5 of life using dried blood spot glucose measurement.

scientific article

Systematic Population Screening, Using Biomarkers and Genetic Testing, Identifies 2.5% of the U.K. Pediatric Diabetes Population With Monogenic Diabetes.

scientific article published on 06 June 2016

The HNF4A R76W mutation causes atypical dominant Fanconi syndrome in addition to a β cell phenotype

scientific article

The association between postprandial urinary C-peptide creatinine ratio and the treatment response to liraglutide: a multi-centre observational study.

scientific article

The development and validation of a clinical prediction model to determine the probability of MODY in patients with young-onset diabetes.

scientific article published on 5 January 2012

The governance structure for data access in the DIRECT consortium: an innovative medicines initiative (IMI) project

scholarly article by Harriet J A Teare et al published 4 September 2018 in Life sciences, society and policy

The impact of gender on urine C-peptide creatinine ratio interpretation

scientific article published on 08 May 2012

The impact of insulin administration during the mixed meal tolerance test

scientific article published in October 2012

The majority of patients with long-duration type 1 diabetes are insulin microsecretors and have functioning beta cells

scientific article published on January 2014

Type 1 diabetes can present before the age of 6 months and is characterised by autoimmunity and rapid loss of beta cells

scientific article published on 08 October 2020

Urinary C-peptide creatinine ratio detects absolute insulin deficiency in Type 2 diabetes.

scientific article

Urinary C-peptide creatinine ratio is a practical outpatient tool for identifying hepatocyte nuclear factor 1-{alpha}/hepatocyte nuclear factor 4-{alpha} maturity-onset diabetes of the young from long-duration type 1 diabetes

scientific article

Urine C-peptide creatinine ratio can be used to assess insulin resistance and insulin production in people without diabetes: an observational study

scientific article (publication date: 18 December 2013)

Urine C-peptide creatinine ratio is a noninvasive alternative to the mixed-meal tolerance test in children and adults with type 1 diabetes ⬇️

scientific article

Urine C-peptide creatinine ratio is an alternative to stimulated serum C-peptide measurement in late-onset, insulin-treated diabetes.

scientific article published in September 2011

Using highly sensitive C-reactive protein measurement to diagnose MODY in a family with suspected type 2 diabetes

scientific article

Validating the positivity thresholds of drug-tolerant anti-infliximab and anti-adalimumab antibody assays

scientific article published on 23 November 2020

Validation of a single-sample urinary C-peptide creatinine ratio as a reproducible alternative to serum C-peptide in patients with Type 2 diabetes

scientific article published in January 2012

Zinc Transporter 8 Autoantibodies (ZnT8A) and a Type 1 Diabetes Genetic Risk Score Can Exclude Individuals With Type 1 Diabetes From Inappropriate Genetic Testing for Monogenic Diabetes

scientific article published on 08 November 2018

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