List of works - Frank Baganz

17 Metabolic Control Analysis as a Tool in the Elucidation of the Function of Novel Genes

article

2,3-Dihydroxyisovalerate production by Klebsiella pneumoniae

scientific article published on 09 June 2020

A Microfluidic System for the Investigation of Tumor Cell Extravasation.

scientific article published on 23 May 2018

A Multidisciplinary Approach Toward the Rapid and Preparative-Scale Biocatalytic Synthesis of Chiral Amino Alcohols: A Concise Transketolase-/ω-Transaminase-Mediated Synthesis of (2S,3S)-2-Aminopentane-1,3-diol

A methodology for centrifuge selection for the separation of high solids density cell broths by visualisation of performance using windows of operation

scientific article published in December 2006

A simple method to determine evaporation and compensate for liquid losses in small-scale cell culture systems.

scientific article

A toolbox approach for the rapid evaluation of multi-step enzymatic syntheses comprising a ‘mix and match’E. coliexpression system with microscale experimentation

Accelerated design of bioconversion processes using automated microscale processing techniques

scientific article

Adapted ultra scale-down approach for predicting the centrifugal separation behavior of high cell density cultures.

scientific article published on 20 October 2007

An efficient approach to bioconversion kinetic model generation based on automated microscale experimentation integrated with model driven experimental design

article

Application of quality by design principles to the development and technology transfer of a major process improvement for the manufacture of a recombinant protein.

scientific article published on 21 September 2011

Assessment of the manufacturability of Escherichia coli high cell density fermentations.

scientific article

Bioprocess considerations for T cell therapy: Investigating the impact of agitation, dissolved oxygen and pH on T cell expansion and differentiation

scientific article published on 22 June 2020

Characterization and application of a miniature 10 mL stirred-tank bioreactor, showing scale-down equivalence with a conventional 7 L reactor

scientific article published in May 2006

Characterization and feasibility of a miniaturized stirred tank bioreactor to perform E. coli high cell density fed-batch fermentations.

scientific article

Characterization and multi-step transketolase-ω-transaminase bioconversions in an immobilized enzyme microreactor (IEMR) with packed tube

scientific article published on 17 September 2013

Characterization of oxygen transfer in miniature and lab-scale bubble column bioreactors and comparison of microbial growth performance based on constant k(L)a

scientific article published in July 2005

Chitosan flocculation to aid the harvesting of the microalga Chlorella sorokiniana

scientific article published on 28 November 2012

Combined remediation and lipid production using Chlorella sorokiniana grown on wastewater and exhaust gases

scientific article

Conscious coupling: The challenges and opportunities of cascading enzymatic microreactors.

scientific article published on 8 May 2017

Customized microscale approach for optimizing two-phase bio-oxidations of alkanes with high reproducibility

scientific article published on 10 October 2017

Design and characterisation of a miniature stirred bioreactor system for parallel microbial fermentations

article by N.K. Gill et al published April 2008 in Biochemical Engineering Journal

Design and characterization of a prototype enzyme microreactor: quantification of immobilized transketolase kinetics.

scientific article

Design and parallelisation of a miniature photobioreactor platform for microalgal culture evaluation and optimisation

article

Digital Twins for Bioprocess Control Strategy Development and Realisation

scientific article published on 20 November 2020

Directed evolution of biocatalytic processes

scientific article

Engineering characterisation of a shaken, single-use photobioreactor for early stage microalgae cultivation using Chlorella sorokiniana

scientific article published on 28 September 2014

Enzymatic synthesis of chiral amino-alcohols by coupling transketolase and transaminase-catalyzed reactions in a cascading continuous-flow microreactor system.

scientific article published on 7 October 2017

Ethylene glycol and glycolic acid production by wild-type Escherichia coli

scientific article published on 19 July 2020

Ethylene glycol and glycolic acid production from xylonic acid by Enterobacter cloacae

scientific article published on 15 April 2020

Evaluation of the effects and interactions of mixing and oxygen transfer on the production of Fab' antibody fragments in Escherichia coli fermentation with gas blending

scientific article published in October 2005

Fed-batch operation of an industrial cell culture process in shaken microwells

scientific article published on 17 September 2009

Fluid mixing in shaken bioreactors: Implications for scale-up predictions from microlitre-scale microbial and mammalian cell cultures

article

High-throughput screening and process optimisation

Identification and use of an alkane transporter plug-in for applications in biocatalysis and whole-cell biosensing of alkanes

scientific article published on 28 July 2014

Identification of erythrobactin, a hydroxamate-type siderophore produced by Saccharopolyspora erythraea

scientific article published in April 2006

Immobilised enzyme microreactor for screening of multi-step bioconversions: Characterisation of a de novo transketolase-ω-transaminase pathway to synthesise chiral amino alcohols

scientific article published on 22 July 2011

Impact of aeration strategies on fed-batch cell culture kinetics in a single-use 24-well miniature bioreactor

article

Improving Product Specificity of Whole-Cell Alkane Oxidation in Nonconventional Media: A Multivariate Analysis Approach

scientific article published on 24 July 2019

Improving recombinant protein production in the Chlamydomonas reinhardtii chloroplast using vivid Verde Fluorescent Protein as a reporter

scientific article published on 22 June 2015

Intelligent modelling of bioprocesses: a comparison of structured and unstructured approaches.

scientific article published on 18 September 2004

Microfluidic approaches for systems and synthetic biology

scientific article published on August 2010

Miniature bioreactors: current practices and future opportunities

scientific article

Modelling and optimisation of the one-pot, multi-enzymatic synthesis of chiral amino-alcohols based on microscale kinetic parameter determination

Modelling surface aeration rates in shaken microtitre plates using dimensionless groups

Modulating the import of medium-chain alkanes in E. coli through tuned expression of FadL.

scientific article

Monitoring and control of microbioreactors: an expert opinion on development needs

scientific article published on 11 September 2012

Multi-step biocatalytic strategies for chiral amino alcohol synthesis.

scientific article published on 10 July 2015

Non-linear kinetic modelling of reversible bioconversions: Application to the transaminase catalyzed synthesis of chiral amino-alcohols

Optimisation of enzyme cascades for chiral amino alcohol synthesis in aid of host cell integration using a statistical experimental design approach

scientific article published on 19 July 2018

Production of 2,3-dihydroxyisovalerate by Enterobacter cloacae

scientific article published on 12 August 2020

Quantification of kinetics for enzyme-catalysed reactions: implications for diffusional limitations at the 10 ml scale.

scientific article published on 26 January 2008

Quantification of power consumption and oxygen transfer characteristics of a stirred miniature bioreactor for predictive fermentation scale-up.

scientific article published in August 2008

Real-time pH monitoring of industrially relevant enzymatic reactions in a microfluidic side-entry reactor (μSER) shows potential for pH control.

scientific article published on 20 January 2017

Simplified immobilisation method for histidine-tagged enzymes in poly(methyl methacrylate) microfluidic devices

scientific article

The Analysis of Multiple Genome Comparisons in Genus Escherichia and Its Application to the Discovery of Uncharacterised Metabolic Genes in Uropathogenic Escherichia coli CFT073.

scientific article

Tools for characterizing the whole-cell bio-oxidation of alkanes at microscale.

scientific article

Towards the development of automated fed-batch cell culture processes at microscale

scientific article published on 18 September 2019

Using a Parallel Micro-Cultivation System (Micro-Matrix) as a Process Development Tool for Cell Culture Applications

scientific article published on 01 January 2020

Whole-cell bio-oxidation of n-dodecane using the alkane hydroxylase system of P. putida GPo1 expressed in E. coli.

scientific article

List of works by Frank Baganz

17 Metabolic Control Analysis as a Tool in the Elucidation of the Function of Novel Genes

2,3-Dihydroxyisovalerate production by Klebsiella pneumoniae

A Microfluidic System for the Investigation of Tumor Cell Extravasation.

A Multidisciplinary Approach Toward the Rapid and Preparative-Scale Biocatalytic Synthesis of Chiral Amino Alcohols: A Concise Transketolase-/ω-Transaminase-Mediated Synthesis of (2S,3S)-2-Aminopentane-1,3-diol

A methodology for centrifuge selection for the separation of high solids density cell broths by visualisation of performance using windows of operation

A simple method to determine evaporation and compensate for liquid losses in small-scale cell culture systems.

A toolbox approach for the rapid evaluation of multi-step enzymatic syntheses comprising a ‘mix and match’E. coliexpression system with microscale experimentation

Accelerated design of bioconversion processes using automated microscale processing techniques

Adapted ultra scale-down approach for predicting the centrifugal separation behavior of high cell density cultures.

An efficient approach to bioconversion kinetic model generation based on automated microscale experimentation integrated with model driven experimental design

Application of quality by design principles to the development and technology transfer of a major process improvement for the manufacture of a recombinant protein.

Assessment of the manufacturability of Escherichia coli high cell density fermentations.

Bioprocess considerations for T cell therapy: Investigating the impact of agitation, dissolved oxygen and pH on T cell expansion and differentiation

Characterization and application of a miniature 10 mL stirred-tank bioreactor, showing scale-down equivalence with a conventional 7 L reactor

Characterization and feasibility of a miniaturized stirred tank bioreactor to perform E. coli high cell density fed-batch fermentations.

Characterization and multi-step transketolase-ω-transaminase bioconversions in an immobilized enzyme microreactor (IEMR) with packed tube

Characterization of oxygen transfer in miniature and lab-scale bubble column bioreactors and comparison of microbial growth performance based on constant k(L)a

Chitosan flocculation to aid the harvesting of the microalga Chlorella sorokiniana

Combined remediation and lipid production using Chlorella sorokiniana grown on wastewater and exhaust gases

Conscious coupling: The challenges and opportunities of cascading enzymatic microreactors.

Customized microscale approach for optimizing two-phase bio-oxidations of alkanes with high reproducibility

Design and characterisation of a miniature stirred bioreactor system for parallel microbial fermentations

Design and characterization of a prototype enzyme microreactor: quantification of immobilized transketolase kinetics.

Design and parallelisation of a miniature photobioreactor platform for microalgal culture evaluation and optimisation

Digital Twins for Bioprocess Control Strategy Development and Realisation

Directed evolution of biocatalytic processes

Engineering characterisation of a shaken, single-use photobioreactor for early stage microalgae cultivation using Chlorella sorokiniana

Enzymatic synthesis of chiral amino-alcohols by coupling transketolase and transaminase-catalyzed reactions in a cascading continuous-flow microreactor system.

Ethylene glycol and glycolic acid production by wild-type Escherichia coli

Ethylene glycol and glycolic acid production from xylonic acid by Enterobacter cloacae

Evaluation of the effects and interactions of mixing and oxygen transfer on the production of Fab' antibody fragments in Escherichia coli fermentation with gas blending

Fed-batch operation of an industrial cell culture process in shaken microwells

Fluid mixing in shaken bioreactors: Implications for scale-up predictions from microlitre-scale microbial and mammalian cell cultures

High-throughput screening and process optimisation

Identification and use of an alkane transporter plug-in for applications in biocatalysis and whole-cell biosensing of alkanes

Identification of erythrobactin, a hydroxamate-type siderophore produced by Saccharopolyspora erythraea

Immobilised enzyme microreactor for screening of multi-step bioconversions: Characterisation of a de novo transketolase-ω-transaminase pathway to synthesise chiral amino alcohols

Impact of aeration strategies on fed-batch cell culture kinetics in a single-use 24-well miniature bioreactor

Improving Product Specificity of Whole-Cell Alkane Oxidation in Nonconventional Media: A Multivariate Analysis Approach

Improving recombinant protein production in the Chlamydomonas reinhardtii chloroplast using vivid Verde Fluorescent Protein as a reporter

Intelligent modelling of bioprocesses: a comparison of structured and unstructured approaches.

Microfluidic approaches for systems and synthetic biology

Miniature bioreactors: current practices and future opportunities

Modelling and optimisation of the one-pot, multi-enzymatic synthesis of chiral amino-alcohols based on microscale kinetic parameter determination

Modelling surface aeration rates in shaken microtitre plates using dimensionless groups

Modulating the import of medium-chain alkanes in E. coli through tuned expression of FadL.

Monitoring and control of microbioreactors: an expert opinion on development needs

Multi-step biocatalytic strategies for chiral amino alcohol synthesis.

Non-linear kinetic modelling of reversible bioconversions: Application to the transaminase catalyzed synthesis of chiral amino-alcohols

Optimisation of enzyme cascades for chiral amino alcohol synthesis in aid of host cell integration using a statistical experimental design approach

Production of 2,3-dihydroxyisovalerate by Enterobacter cloacae

Quantification of kinetics for enzyme-catalysed reactions: implications for diffusional limitations at the 10 ml scale.

Quantification of power consumption and oxygen transfer characteristics of a stirred miniature bioreactor for predictive fermentation scale-up.

Real-time pH monitoring of industrially relevant enzymatic reactions in a microfluidic side-entry reactor (μSER) shows potential for pH control.

Simplified immobilisation method for histidine-tagged enzymes in poly(methyl methacrylate) microfluidic devices

The Analysis of Multiple Genome Comparisons in Genus Escherichia and Its Application to the Discovery of Uncharacterised Metabolic Genes in Uropathogenic Escherichia coli CFT073.

Tools for characterizing the whole-cell bio-oxidation of alkanes at microscale.

Towards the development of automated fed-batch cell culture processes at microscale

Using a Parallel Micro-Cultivation System (Micro-Matrix) as a Process Development Tool for Cell Culture Applications

Whole-cell bio-oxidation of n-dodecane using the alkane hydroxylase system of P. putida GPo1 expressed in E. coli.

pH control in microwell fermentations of S. erythraea CA340: influence on biomass growth kinetics and erythromycin biosynthesis

α, α -Dihydroxy Ketones and 2-Amino-1,3-diols: Synthetic and Process Strategies Using Biocatalysts