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List of works by Martin Feelisch

A chemiluminescense-based assay for S-nitrosoalbumin and other plasma S-nitrosothiols

scientific article published on 01 January 2000

A multilevel analytical approach for detection and visualization of intracellular NO production and nitrosation events using diaminofluoresceins

scientific article

A randomized double-blind placebo-controlled crossover trial of sodium nitrate in patients with stable angina INAS.

scientific article published on 12 October 2016

A robust and versatile mass spectrometry platform for comprehensive assessment of the thiol redox metabolome.

scientific article published on 19 February 2018

A time for everything and everything in its time - exploring the mechanisms underlying seasonality of COPD exacerbations

scholarly article by Alexander Hicks et al published 5 September 2018 in International Journal of Chronic Obstructive Pulmonary Disease

Acute Dietary Nitrate Supplementation and Exercise Performance in COPD: A Double-Blind, Placebo-Controlled, Randomised Controlled Pilot Study

scientific article published on 23 December 2015

Ammonium tetrathiomolybdate following ischemia/reperfusion injury: Chemistry, pharmacology, and impact of a new class of sulfide donor in preclinical injury models.

scientific article

An integrated approach to assessing nitroso-redox balance in systemic inflammation

scientific article published on 14 June 2011

Application of an optimized total N-nitrosamine (TONO) assay to pools: placing N-nitrosodimethylamine (NDMA) determinations into perspective.

scientific article published in May 2010

Autoinhibition of neuronal nitric oxide synthase: distinct effects of reactive nitrogen and oxygen species on enzyme activity.

scientific article published in June 1999

Autologous transfusion of stored red blood cells increases pulmonary artery pressure.

scientific article

Beetroot juice versus chard gel: A pharmacokinetic and pharmacodynamic comparison of nitrate bioavailability.

scientific article published on 29 December 2016

Bioassay discrimination between nitric oxide (NO.) and nitroxyl (NO-) using L-cysteine

scientific article published on 01 May 1994

Biochemical characterization of S-nitrosohemoglobin. Mechanisms underlying synthesis, no release, and biological activity

scientific article published on 01 October 1999

Blueberries improve biomarkers of cardiometabolic function in participants with metabolic syndrome-results from a 6-month, double-blind, randomized controlled trial

scientific article published on 01 June 2019

Bound NO in human red blood cells: fact or artifact?

scientific article

Brief periods of nitric oxide inhalation protect against myocardial ischemia-reperfusion injury

scientific article published on October 2008

Can skin exposure to sunlight prevent liver inflammation?

scientific article published on 5 May 2015

Cardiomyocyte-specific overexpression of NO synthase-3 protects against myocardial ischemia-reperfusion injury.

scientific article published on 27 April 2006

Cardioprotective effects of vegetables: is nitrate the answer?

scientific article published on 24 March 2006

Cellular targets and mechanisms of nitros(yl)ation: an insight into their nature and kinetics in vivo.

scholarly article

Cephalosporin nitric oxide-donor prodrug DEA-C3D disperses biofilms formed by clinical cystic fibrosis isolates of Pseudomonas aeruginosa

scientific article published on 01 January 2020

Cephalosporin-3'-Diazeniumdiolate NO Donor Prodrug PYRRO-C3D Enhances Azithromycin Susceptibility of Nontypeable Haemophilus influenzae Biofilms.

scientific article published on 05 December 2016

Cephalosporin-NO-donor prodrug PYRRO-C3D shows β-lactam-mediated activity against Streptococcus pneumoniae biofilms.

scientific article published on 21 February 2017

Changes in acute pulmonary vascular responsiveness to hypoxia during a progressive ascent to high altitude (5300 m).

scientific article published on 8 April 2017

Characterising nitric oxide-mediated metabolic benefits of low-dose ultraviolet radiation in the mouse: a focus on brown adipose tissue

scientific article published on 11 November 2019

Chemical nature of nitric oxide storage forms in rat vascular tissue.

scholarly article

Chemistry, pharmacology, and cellular uptake mechanisms of thiometallate sulfide donors

scientific article published on 23 May 2019

Circulating NO pool: assessment of nitrite and nitroso species in blood and tissues.

scientific article published on February 2004

Circulating biomarkers of nitric oxide bioactivity and impaired muscle vasoreactivity to exercise in adults with uncomplicated type 1 diabetes

scientific article published on 21 November 2020

Comparison of the reactivity of nitric oxide and nitroxyl with heme proteins. A chemical discussion of the differential biological effects of these redox related products of NOS.

scientific article published in January 2003

Correlation between nitric oxide formation during degradation of organic nitrates and activation of guanylate cyclase.

scientific article published on July 1987

Cysteinyl-tRNA synthetase governs cysteine polysulfidation and mitochondrial bioenergetics.

scientific article published on 27 October 2017

DL-propargylglycine reduces blood pressure and renal injury but increases kidney weight in angiotensin-II infused rats

scientific article published on 17 July 2015

Dermal Nitrite Application Enhances Global Nitric Oxide Availability: New Therapeutic Potential for Immunomodulation?

article

Design and conduct of 'Xtreme Alps': a double-blind, randomised controlled study of the effects of dietary nitrate supplementation on acclimatisation to high altitude

scientific article

Design and conduct of Xtreme Everest 2: An observational cohort study of Sherpa and lowlander responses to graduated hypobaric hypoxia.

scientific article

Dietary nitrate increases arginine availability and protects mitochondrial complex I and energetics in the hypoxic rat heart.

scientific article

Direct biochemical evidence for eNOS stimulation by bradykinin in the human forearm vasculature.

scientific article published in March 2003

Does hypoxia play a role in the development of sarcopenia in humans? Mechanistic insights from the Caudwell Xtreme Everest Expedition

scientific article

Dynamic state of S-nitrosothiols in human plasma and whole blood

scientific article published on 01 February 2000

Effect of nitric oxide donors on neointima formation and vascular reactivity in the collared carotid artery of rabbits

scientific article published on 01 August 1995

Effects of dietary nitrate on respiratory physiology at high altitude - Results from the Xtreme Alps study.

scientific article published on 14 October 2017

Effects of dietary nitrate supplementation on microvascular physiology at 4559 m altitude - A randomised controlled trial (Xtreme Alps)

scientific article published on 08 October 2019

Effects of dietary nitrate supplementation on symptoms of acute mountain sickness and basic physiological responses in a group of male adolescents during ascent to Mount Everest Base Camp.

scientific article

Effects of prolonged exposure to hypobaric hypoxia on oxidative stress, inflammation and gluco-insular regulation: the not-so-sweet price for good regulation

scientific article

Electron-paramagnetic resonance spectroscopy using N-methyl-D-glucamine dithiocarbamate iron cannot discriminate between nitric oxide and nitroxyl: implications for the detection of reaction products for nitric oxide synthase

scientific article published on 01 March 2000

Embracing sulfide and CO to understand nitric oxide biology

scientific article published on 13 June 2013

Endogenous H2S production deficiencies lead to impaired renal erythropoietin production

scientific article published on 20 November 2018

Erythropoietin and a nonerythropoietic peptide analog promote aortic endothelial cell repair under hypoxic conditions: role of nitric oxide

scientific article published on 16 August 2016

Evidence for in vivo transport of bioactive nitric oxide in human plasma.

scientific article

Explanation of the discrepancy between the degree of organic nitrate decomposition, nitrite formation and guanylate cyclase stimulation

scientific article published on 01 January 1988

Exposure of Stored Packed Erythrocytes to Nitric Oxide Prevents Transfusion-associated Pulmonary Hypertension.

scientific article published on 12 August 2016

Genetic overexpression of eNOS attenuates hepatic ischemia-reperfusion injury

article

Getting the most from venous occlusion plethysmography: proposed methods for the analysis of data with a rest/exercise protocol.

scientific article

Glutathione peroxidase deficiency exacerbates ischemia-reperfusion injury in male but not female myocardium: insights into antioxidant compensatory mechanisms

scientific article published on 02 October 2009

Guide for the use of nitric oxide (NO) donors as probes of the chemistry of NO and related redox species in biological systems

scientific article published on 01 January 2002

Higher blood flow and circulating NO products offset high-altitude hypoxia among Tibetans.

scholarly article

Human Second Window Pre-Conditioning and Post-Conditioning by Nitrite Is Influenced by a Common Polymorphism in Mitochondrial Aldehyde Dehydrogenase

scientific article published on 15 February 2017

Human endothelial cells bioactivate organic nitrates to nitric oxide: implications for the reinforcement of endothelial defence mechanisms.

scientific article

Human red blood cells at work: identification and visualization of erythrocytic eNOS activity in health and disease

scientific article

Hydrogen sulfide attenuates calcification of vascular smooth muscle cells via KEAP1/NRF2/NQO1 activation

scientific article published on 19 August 2017

Hyperoxia-induced lung injury in gamma-glutamyl transferase deficiency is associated with alterations in nitrosative and nitrative stress.

scientific article published on 22 October 2009

Identification of N-iminoethyl-l-ornithine as an irreversible inhibitor of nitric oxide synthase in phagocytic cells

scientific article published on January 1, 1991

Identification of a soluble guanylate cyclase in RBCs: preserved activity in patients with coronary artery disease

scientific article

Impaired effectiveness of nitric oxide-donors in resistance arteries of patients with arterial hypertension

scientific article published on 01 July 1996

Impaired sodium-dependent adaptation of arterial stiffness in formerly preeclamptic women: the RETAP-vascular study

scientific article published on 08 April 2016

Inhaled Nitric Oxide as an Adjunctive Treatment for Cerebral Malaria in Children: A Phase II Randomized Open-Label Clinical Trial

scientific article

Inorganic Nitrate Mimics Exercise-Stimulated Muscular Fiber-Type Switching and Myokine and γ-Aminobutyric Acid Release

scientific article published on 27 December 2016

Inorganic Nitrate in Angina Study: A Randomized Double-Blind Placebo-Controlled Trial

scientific article published on 8 September 2017

Inorganic nitrate and nitrite supplementation fails to improve skeletal muscle mitochondrial efficiency in mice and humans

scientific article published on 01 January 2020

Inorganic nitrate promotes the browning of white adipose tissue through the nitrate-nitrite-nitric oxide pathway

scientific article

Inorganic sulfur-nitrogen compounds: from gunpowder chemistry to the forefront of biological signaling

scientific article published on 22 February 2016

Integrating nitric oxide, nitrite and hydrogen sulfide signaling in the physiological adaptations to hypoxia: A comparative approach

scientific article published on 31 January 2012

Intravenous sodium nitrite in acute ST-elevation myocardial infarction: a randomized controlled trial (NIAMI)

scientific article

Investigations on the role of hemoglobin in sulfide metabolism by intact human red blood cells

scientific article published on 30 January 2018

Is sunlight good for our heart?

scientific article published on 09 March 2010

Isotope tracing enhancement of chemiluminescence assays for nitric oxide research.

scientific article

Key bioactive reaction products of the NO/H2S interaction are S/N-hybrid species, polysulfides, and nitroxyl.

scientific article

Long-lasting blood pressure lowering effects of nitrite are NO-independent and mediated by hydrogen peroxide, persulfides, and oxidation of protein kinase G1α redox signalling

scientific article published on 01 January 2020

Low Concentrations of Nitric Oxide Modulate Streptococcus pneumoniae Biofilm Metabolism and Antibiotic Tolerance.

scientific article published on 8 February 2016

Low plasma homoarginine concentration is associated with high rates of all-cause mortality in renal transplant recipients

scientific article published on 20 April 2017

Low-Dose Nitric Oxide as Targeted Anti-biofilm Adjunctive Therapy to Treat Chronic Pseudomonas aeruginosa Infection in Cystic Fibrosis

scientific article

Lower limb ischemic preconditioning combined with dietary nitrate supplementation does not influence time-trial performance in well-trained cyclists

scientific article published on 26 January 2019

Manganese Porphyrin-Based SOD Mimetics Produce Polysulfides from Hydrogen Sulfide

scientific article published on 12 December 2019

Measurement of in vivo nitric oxide synthesis in humans using stable isotopic methods: a systematic review.

scientific article published on 13 June 2011

Mechanisms of cell death governed by the balance between nitrosative and oxidative stress.

scientific article

Mechanisms of histamine-induced coronary vasodilatation: H1-receptor-mediated release of endothelium-derived nitric oxide.

scientific article published in May 1993

Mechanisms of the antioxidant effects of nitric oxide.

scientific article published in April 2001

Mechanistic insights into nitrite-induced cardioprotection using an integrated metabolomic/proteomic approach.

scientific article published on 19 February 2009

Metabolic adjustment to high-altitude hypoxia: from genetic signals to physiological implications

scientific article published on 20 April 2018

Metabolic basis to Sherpa altitude adaptation

scientific article

Metabolism of hydrogen sulfide (H2S) and Production of Reactive Sulfur Species (RSS) by superoxide dismutase

scientific article

Modulation of nitrosative stress by S-nitrosoglutathione reductase is critical for thermotolerance and plant growth in Arabidopsis

scientific article published on 7 March 2008

Moexipril, a new angiotensin-converting enzyme (ACE) inhibitor: pharmacological characterization and comparison with enalapril

scientific article published on 01 November 1995

Molecular aspects underlying the vasodilator action of molsidomine.

scientific article published in January 1989

Molecular mechanisms of nitrovasodilator bioactivation.

scientific article

N-Nitroso products from the reaction of indoles with Angeli's salt.

scientific article published on January 2006

NO adducts in mammalian red blood cells: too much or too little?

scientific article published on 01 May 2003

Nitrate enhances skeletal muscle fatty acid oxidation via a nitric oxide-cGMP-PPAR-mediated mechanism

scientific article published on 22 December 2015

Nitrated cyclic GMP as a new cellular signal.

scientific article

Nitric oxide (NO) formation from nitrovasodilators occurs independently of hemoglobin or non-heme iron

scientific article published on 01 October 1987

Nitric oxide modulates endotoxin-induced platelet-endothelial cell adhesion in intestinal venules.

scientific article published in March 2002

Nitric oxide modulates sympathetic neurotransmission at the prejunctional level.

scientific article

Nitrite circumvents platelet resistance to nitric oxide in patients with heart failure preserved ejection fraction and chronic atrial fibrillation

scientific article published on 12 April 2018

Nitrite mediated vasorelaxation in human chorionic plate vessels is enhanced by hypoxia and dependent on the NO-sGC-cGMP pathway

scientific article published on 01 September 2018

Nitrosative stress in an animal model of necrotizing enterocolitis.

scientific article published on 19 August 2005

Nitroso-redox status and vascular function in marginal and severe ascorbate deficiency.

scientific article

Nitrosopersulfide (SSNO(-)) accounts for sustained NO bioactivity of S-nitrosothiols following reaction with sulfide

scientific article published on 11 January 2014

Nitrosopersulfide (SSNO-) targets soluble guanylyl cyclase and induces vasodilation in vivo

scientific article published on 2 September 2015

Nitrosopersulfide (SSNO-) targets the Keap-1/Nrf2 redox system

scientific article published on 20 September 2016

Nitroxyl affords thiol-sensitive myocardial protective effects akin to early preconditioning.

scientific article

Nitroxyl anion exerts redox-sensitive positive cardiac inotropy in vivo by calcitonin gene-related peptide signaling.

scientific article

Nitroxyl gets to the heart of the matter.

scientific article

Nitroxyl oxidizes NADPH in a superoxide dismutase inhibitable manner

scientific article

Novel organic nitrates are potent dilators of large coronary arteries with reduced development of tolerance during long-term infusion in dogs: role of the sulfhydryl moiety

scientific article published on 01 May 1994

Nrf2 Deficiency Unmasks the Significance of Nitric Oxide Synthase Activity for Cardioprotection.

scientific article published on 30 April 2018

On the Effects of Reactive Oxygen Species and Nitric Oxide on Red Blood Cell Deformability.

scientific article

On the chemical biology of the nitrite/sulfide interaction.

scientific article published on 23 December 2014

Orthogonal properties of the redox siblings nitroxyl and nitric oxide in the cardiovascular system: a novel redox paradigm.

scientific article

Oxidation and nitrosation of thiols at low micromolar exposure to nitric oxide. Evidence for a free radical mechanism.

scientific article published on 20 February 2003

Performance of diamino fluorophores for the localization of sources and targets of nitric oxide.

scientific article published in February 2005

Persistent inhibition of cell respiration by nitric oxide: crucial role of S-nitrosylation of mitochondrial complex I and protective action of glutathione.

scientific article published on June 1998

Pharmacological preconditioning with inhaled nitric oxide (NO): Organ-specific differences in the lifetime of blood and tissue NO metabolites

scientific article published on 13 August 2018

Pharmacology and therapeutic role of inorganic nitrite and nitrate in vasodilatation

scientific article published on 30 June 2014

Plasma nitroso compounds are decreased in patients with endothelial dysfunction

scientific article published on 18 January 2006

Preferential dilation of large coronary microvessels by the mononitrates SPM-4744 and SPM-5185.

scientific article published on April 1996

Pushing arterial-venous plasma biomarkers to new heights: A model for personalised redox metabolomics?

scientific article published on 22 January 2019

Rapid free thiol rebound is a physiological response following cold-induced vasoconstriction in healthy humans, primary Raynaud and systemic sclerosis

scientific article published on 01 March 2019

Reactive Species Interactome Alterations in Oocyte Donation Pregnancies in the Absence and Presence of Pre-Eclampsia

scientific article published on 06 March 2019

Red Blood Cell-Derived Nitric Oxide Bioactivity and Hypoxic Vasodilation

scientific article published on 03 June 2019

Redox-sensitivity and site-specificity of S- and N- denitrosation in proteins

scientific article

Release of endothelium derived nitric oxide in relation to pressure and flow.

scientific article

Role of nitric oxide in the regulation of coronary vascular tone in hearts from hypertensive rats. Maintenance of nitric oxide-forming capacity and increased basal production of nitric oxide.

scientific article published in February 1995

SP/W-5186, A cysteine-containing nitric oxide donor, attenuates postischemic myocardial injury

scientific article published on 01 November 1998

Serum free sulfhydryl status is associated with patient and graft survival in renal transplant recipients.

scientific article published on 20 August 2016

Serum free thiols in chronic heart failure

scientific article published in July 2016

Serum free thiols in type 2 diabetes mellitus: A prospective study

scientific article published on 28 February 2019

Short-term hypoxic vasodilation in vivo is mediated by bioactive nitric oxide metabolites, rather than free nitric oxide derived from haemoglobin-mediated nitrite reduction

scientific article published on 06 January 2014

Short-term intravenous sodium nitrite infusion improves cardiac and pulmonary hemodynamics in heart failure patients.

scientific article published on 2 April 2015

Speciation of reactive sulfur species and their reactions with alkylating agents: do we have any clue about what is present inside the cell?

scientific article published on 23 August 2018

Study of the Operation of an Industrial Water Treatment Plant of the Northern Soft Drink Company Fez, Morocco

scientific article published in 2022

Sub-erythemal ultraviolet radiation reduces metabolic dysfunction in already overweight mice

scientific article published on 2 February 2017

Superoxide dismutase and catalase are required to detect (.-)NO from both coupled and uncoupled neuronal no synthase.

scientific article published in October 2004

Suppression of TAK1 pathway by shear stress counteracts the inflammatory endothelial cell phenotype induced by oxidative stress and TGF-β1.

scientific article published on 17 February 2017

Suppression of erythropoiesis by dietary nitrate.

scientific article published on 24 November 2014

The Reactive Species Interactome: Evolutionary Emergence, Biological Significance, and Opportunities for Redox Metabolomics and Personalized Medicine.

scientific article published on 11 April 2017

The activation of metabolites of nitric oxide synthase by metals is both redox and oxygen dependent: a new feature of nitrogen oxide signaling

scientific article published on July 2006

The chemical biology of nitric oxide--an outsider's reflections about its role in osteoarthritis.

scientific article published on January 2008

The cytotoxicity of nitroxyl: possible implications for the pathophysiological role of NO.

scientific article

The early role of nitric oxide in evolution

scientific article published on 01 December 1995

The effects of two different doses of ultraviolet-A light exposure on nitric oxide metabolites and cardiorespiratory outcomes.

scientific article published on 7 March 2018

The emerging biology of the nitrite anion

scientific article published on 01 November 2005

The fate of sulfate in chronic heart failure

scientific article published on 6 December 2016

The key role of nitric oxide in hypoxia: hypoxic vasodilation and energy supply-demand matching

scientific article published on March 2013

The nitric oxide/superoxide assay. Insights into the biological chemistry of the NO/O-2. interaction

scientific article published on 01 April 1997

The reaction products of sulfide and S-nitrosoglutathione are potent vasorelaxants

scientific article published on 18 December 2014

The role of nitric oxide in the regulation of coronary vascular resistance in arterial hypertension: comparison of normotensive and spontaneously hypertensive rats.

scientific article

The role of nitrogen oxides in human adaptation to hypoxia

scientific article published on 6 October 2011

The role of vascular myoglobin in nitrite-mediated blood vessel relaxation

scientific article

The soluble guanylyl cyclase inhibitor 1H-[1,2,4]oxadiazolo[4,3,-a] quinoxalin-1-one is a nonselective heme protein inhibitor of nitric oxide synthase and other cytochrome P-450 enzymes involved in nitric oxide donor bioactivation

scientific article published on 01 August 1999

The use of nitric oxide donors in pharmacological studies

scientific article published on July 1, 1998

Therapeutic uses of inorganic nitrite and nitrate: from the past to the future.

scientific article published in April 2008

Tissue processing of nitrite in hypoxia: an intricate interplay of nitric oxide-generating and -scavenging systems

scientific article published on 3 October 2008

UVA Irradiation of Human Skin Vasodilates Arterial Vasculature and Lowers Blood Pressure Independently of Nitric Oxide Synthase

scientific article published on 20 January 2014

Ultraviolet radiation suppresses obesity and symptoms of metabolic syndrome independently of vitamin D in mice fed a high-fat diet

scientific article published in November 2014

Ultraviolet radiation, vitamin D and the development of obesity, metabolic syndrome and type-2 diabetes.

scientific article published on 23 December 2016

Understanding the controversy over the identity of EDRF

scientific article published in Nature

Urinary Excretion of Sulfur Metabolites and Risk of Cardiovascular Events and All-Cause Mortality in the General Population

scientific article published on 25 July 2018

VEGF is indirectly associated with NO production and acutely increases in response to hyperglycaemia(1).

scientific article published on 8 May 2012

Vasodilator effects of PGE1 in the coronary and systemic circulation of the rat are mediated by ATP-sensitive potassium (K+) channels.

scientific article

Vitamin D and allergic airway disease shape the murine lung microbiome in a sex-specific manner

scientific article published on 21 September 2016

Vitamin D status and ill health

[Nitrogen monoxide (NO)--the active principle of organic nitrates]

scientific article published on 01 October 1993