List of works - David Sept

14-3-3 Negatively Regulates Actin Filament Formation In The Deep Branching Eukaryote Giardia lamblia

14-3-3 Regulates Actin Filament Formation in the Deep-Branching Eukaryote Giardia lamblia.

scientific article published on 13 September 2017

A Landau-Ginzburg Model of the Co-existence of Free Tubulin and Assembled Microtubules in Nucleation and Oscillations Phenomena

scientific article

A genetic dissection of Aip1p's interactions leads to a model for Aip1p-cofilin cooperative activities

scientific article

A method for multiprotein assembly in cells reveals independent action of kinesins in complex

scientific article

A model for the interfacial kinetics of phospholipase D activity on long-chain lipids

scientific article published on July 2013

A multiscale model linking ion-channel molecular dynamics and electrostatics to the cardiac action potential

scientific article

A22 disrupts the bacterial actin cytoskeleton by directly binding and inducing a low-affinity state in MreB

scientific article published on June 2009

An actin cytoskeleton with evolutionarily conserved functions in the absence of canonical actin-binding proteins

scientific article

An actin-filament-binding interface on the Arp2/3 complex is critical for nucleation and branch stability

scientific article

An electric-eel-inspired soft power source from stacked hydrogels.

scientific article published in December 2017

An epilepsy/dyskinesia-associated mutation enhances BK channel activation by potentiating Ca2+ sensing

scientific article

Assessing the barriers to image-guided drug delivery

scientific article

Binding and interaction of dinitroanilines with apicomplexan and kinetoplastid alpha-tubulin

scientific article published in August 2006

Binding of myotrophin/V-1 to actin-capping protein: implications for how capping protein binds to the filament barbed end

scientific article

Capping protein regulators fine-tune actin assembly dynamics

scientific article

Carboxyl group footprinting mass spectrometry and molecular dynamics identify key interactions in the HER2-HER3 receptor tyrosine kinase interface

scientific article published on 10 July 2013

Comments on phase-front propagation in ferroelectrics

Commitment to folded and aggregated states occurs late in interleukin-1 beta folding

scientific article

Crossover effects for critical currents within Landau-Ginzburg phenomenology incorporating Josephson weak links in superconducting thin films ofYBaCu2O7−δ

scholarly article by J. A. Tuszyński et al published 1 October 1999 in Physical Review B

Cytokine receptor-Eb1 interaction couples cell polarity and fate during asymmetric cell division.

scientific article published on 26 March 2018

Dinitroaniline activity in Toxoplasma gondii expressing wild-type or mutant alpha-tubulin.

scientific article

Dinitroanilines bind alpha-tubulin to disrupt microtubules

scientific article published on 23 January 2004

Drug-like leads for steric discrimination between substrate and inhibitors of human acetylcholinesterase

scientific article published on 22 August 2011

Effects of Lipid Tethering in Extremophile-Inspired Membranes on H(+)/OH(-) Flux at Room Temperature

scientific article published on June 2016

Effects of distance dependence of exciton hopping on exciton propagation in Scheibe aggregates

Effects of distance dependence of exciton hopping on the Davydov soliton

article

Effects of solution crowding on actin polymerization reveal the energetic basis for nucleotide-dependent filament stability

scientific article published on 20 February 2008

Electrostatics of nanosystems: application to microtubules and the ribosome

scientific article

Energetics and dynamics of constrained actin filament bundling

scientific article

Entropic effects enable life at extreme temperatures

scientific article published on 01 May 2019

Erratum: Capping protein regulators fine-tune actin assembly dynamics

article

Evolutionarily divergent, unstable filamentous actin is essential for gliding motility in apicomplexan parasites

scientific article

F-actin structure destabilization and DNase I binding loop: fluctuations mutational cross-linking and electron microscopy analysis of loop states and effects on F-actin

scientific article

First-contact time to a patch in a multidimensional potential well

scientific article published on 9 August 2007

Frequency-based analysis of gramicidin A nanopores enable detection of small molecules with picomolar sensitivity.

scientific article published on 21 December 2017

Genome-wide analysis reveals novel and discrete functions for tubulin carboxy-terminal tails

scientific article

Hybrid Lipids Inspired by Extremophiles and Eukaryotes Afford Serum-Stable Membranes with Low Leakage.

scientific article published on 29 March 2017

Hydrogel-assisted functional reconstitution of human P-glycoprotein (ABCB1) in giant liposomes

scientific article

Inhomogeneous nucleation in first-order phase transitions

scientific article published on 01 December 1994

Introduction to the Special Issue Dedicated to the Memory of Alan J. Hunt

Kinesin-binding protein remodels the kinesin motor to prevent microtubule binding

scientific article published on 19 November 2021

Localization of the antimitotic peptide and depsipeptide binding site on beta-tubulin

scientific article published in November 2004

Making drug design second nature

article by Dan L. Sackett & David Sept published November 2009 in Nature Chemistry

Mapping the cofilin binding site on yeast G-actin by chemical cross-linking

scientific article

Mathematical modeling of cell migration

scientific article published on January 2008

Mechanical Properties of Doubly Stabilized Microtubule Filaments ⬇️

scientific article published on April 2, 2013

Mechanism for CARMIL protein inhibition of heterodimeric actin-capping protein

scientific article

Mechanisms of kinetic stabilization by the drugs paclitaxel and vinblastine.

scientific article

Microtubule elasticity: connecting all-atom simulations with continuum mechanics

scientific article published on 4 January 2010

Microtubule polymerization: one step at a time

scientific article published in September 2007

Microtubules: Sizing Up the GTP Cap

article

Model for spatial microtubule oscillations.

scientific article published in July 1999

Modeling large-scale dynamic processes in the cell: polarization, waves, and division

scientific article

Models of the collective behavior of proteins in cells: tubulin, actin and motor proteins

scientific article

Molecular modeling of the cytoskeleton

scientific article published in January 2008

Multisite Ion Models That Improve Coordination and Free Energy Calculations in Molecular Dynamics Simulations

scientific article published on 18 July 2013

Multivariate analyses of amyloid-beta oligomer populations indicate a connection between pore formation and cytotoxicity

scientific article

Mutations in alpha-tubulin confer dinitroaniline resistance at a cost to microtubule function

scientific article

Myo1c binds phosphoinositides through a putative pleckstrin homology domain

scientific article

Nanoparticle pharmacokinetic profiling in vivo using magnetic resonance imaging

scientific article published on December 2008

Neurodegeneration mutations in dynactin impair dynein-dependent nuclear migration.

scientific article

New insights into mechanism and regulation of actin capping protein.

scientific article published on January 2008

Novel α-tubulin mutation disrupts neural development and tubulin proteostasis

scientific article

Nucleotide effects on the structure and dynamics of actin

scientific article published on 25 May 2007

Orthogonal trajectories and analytical solutions of the van der Pol equation without forcing

Overlapping and distinct functions for cofilin, coronin and Aip1 in actin dynamics in vivo

scientific article

Perturbations in Microtubule Mechanics from Tubulin Preparation

Pharmacokinetic modeling of tumor bioluminescence implicates efflux, and not influx, as the bigger hurdle in cancer drug therapy

scientific article

Properties of Microtubules with Isotropic and Anisotropic Mechanics

article

Real-time shape approximation and fingerprinting of single proteins using a nanopore

scientific article

Sampling and statistics in biomolecular simulations

Scaling relations in the spherically symmetric Landau—Ginzburg model and a possible connection with self-organized criticality

Single-particle characterization of Aβ oligomers in solution

scientific article

Stochastic data analysis for the assembly and disassembly of microtubules in vitro

Structure/function analysis of the interaction of phosphatidylinositol 4,5-bisphosphate with actin-capping protein: implications for how capping protein binds the actin filament

scientific article

Synthesis of chondramide A analogues with modified β-tyrosine and their biological evaluation

scientific article published on 20 October 2011

Synthetic chondramide A analogues stabilize filamentous actin and block invasion by Toxoplasma gondii ⬇️

scientific article published on 10 September 2013

Taxol allosterically alters the dynamics of the tubulin dimer and increases the flexibility of microtubules

scientific article published on 11 July 2008

The NH2 terminus of RCK1 domain regulates Ca2+-dependent BK(Ca) channel gating

scientific article

The basic concepts of molecular modeling

scientific article published in January 2009

The interaction of capping protein with the barbed end of the actin filament.

scientific article

The interaction of cofilin with the actin filament

scientific article

The kinetics of cooperative cofilin binding reveals two states of the cofilin-actin filament

scientific article

The physical basis of microtubule structure and stability ⬇️

scientific article published on October 1, 2003

The unusual dynamics of parasite actin result from isodesmic polymerization

scientific article

Thermodynamics and kinetics of actin filament nucleation.

scientific article

Topological considerations regarding critical currents in the Landau-Ginzburg model

Two Deafness-Causing Actin Mutations (DFNA20/26) Have Allosteric Effects on the Actin Structure

scientific article published on July 2016

Unusual kinetic and structural properties control rapid assembly and turnover of actin in the parasite Toxoplasma gondii

scientific article

List of works by David Sept

14-3-3 Negatively Regulates Actin Filament Formation In The Deep Branching Eukaryote Giardia lamblia

14-3-3 Regulates Actin Filament Formation in the Deep-Branching Eukaryote Giardia lamblia.

A Landau-Ginzburg Model of the Co-existence of Free Tubulin and Assembled Microtubules in Nucleation and Oscillations Phenomena

A genetic dissection of Aip1p's interactions leads to a model for Aip1p-cofilin cooperative activities

A method for multiprotein assembly in cells reveals independent action of kinesins in complex

A model for the interfacial kinetics of phospholipase D activity on long-chain lipids

A multiscale model linking ion-channel molecular dynamics and electrostatics to the cardiac action potential

A22 disrupts the bacterial actin cytoskeleton by directly binding and inducing a low-affinity state in MreB

An actin cytoskeleton with evolutionarily conserved functions in the absence of canonical actin-binding proteins

An actin-filament-binding interface on the Arp2/3 complex is critical for nucleation and branch stability

An electric-eel-inspired soft power source from stacked hydrogels.

An epilepsy/dyskinesia-associated mutation enhances BK channel activation by potentiating Ca2+ sensing

Assessing the barriers to image-guided drug delivery

Binding and interaction of dinitroanilines with apicomplexan and kinetoplastid alpha-tubulin

Binding of myotrophin/V-1 to actin-capping protein: implications for how capping protein binds to the filament barbed end

Capping protein regulators fine-tune actin assembly dynamics

Carboxyl group footprinting mass spectrometry and molecular dynamics identify key interactions in the HER2-HER3 receptor tyrosine kinase interface

Comments on phase-front propagation in ferroelectrics

Commitment to folded and aggregated states occurs late in interleukin-1 beta folding

Crossover effects for critical currents within Landau-Ginzburg phenomenology incorporating Josephson weak links in superconducting thin films ofYBaCu2O7−δ

Cytokine receptor-Eb1 interaction couples cell polarity and fate during asymmetric cell division.

Dinitroaniline activity in Toxoplasma gondii expressing wild-type or mutant alpha-tubulin.

Dinitroanilines bind alpha-tubulin to disrupt microtubules

Drug-like leads for steric discrimination between substrate and inhibitors of human acetylcholinesterase

Effects of Lipid Tethering in Extremophile-Inspired Membranes on H(+)/OH(-) Flux at Room Temperature

Effects of distance dependence of exciton hopping on exciton propagation in Scheibe aggregates

Effects of distance dependence of exciton hopping on the Davydov soliton

Effects of solution crowding on actin polymerization reveal the energetic basis for nucleotide-dependent filament stability

Electrostatics of nanosystems: application to microtubules and the ribosome

Energetics and dynamics of constrained actin filament bundling

Entropic effects enable life at extreme temperatures

Erratum: Capping protein regulators fine-tune actin assembly dynamics

Evolutionarily divergent, unstable filamentous actin is essential for gliding motility in apicomplexan parasites

F-actin structure destabilization and DNase I binding loop: fluctuations mutational cross-linking and electron microscopy analysis of loop states and effects on F-actin

First-contact time to a patch in a multidimensional potential well

Frequency-based analysis of gramicidin A nanopores enable detection of small molecules with picomolar sensitivity.

Genome-wide analysis reveals novel and discrete functions for tubulin carboxy-terminal tails

Hybrid Lipids Inspired by Extremophiles and Eukaryotes Afford Serum-Stable Membranes with Low Leakage.

Hydrogel-assisted functional reconstitution of human P-glycoprotein (ABCB1) in giant liposomes

Inhomogeneous nucleation in first-order phase transitions

Introduction to the Special Issue Dedicated to the Memory of Alan J. Hunt

Kinesin-binding protein remodels the kinesin motor to prevent microtubule binding

Localization of the antimitotic peptide and depsipeptide binding site on beta-tubulin

Making drug design second nature

Mapping the cofilin binding site on yeast G-actin by chemical cross-linking

Mathematical modeling of cell migration

Mechanical Properties of Doubly Stabilized Microtubule Filaments ⬇️

Mechanism for CARMIL protein inhibition of heterodimeric actin-capping protein

Mechanisms of kinetic stabilization by the drugs paclitaxel and vinblastine.

Microtubule elasticity: connecting all-atom simulations with continuum mechanics

Microtubule polymerization: one step at a time

Microtubules: Sizing Up the GTP Cap

Model for spatial microtubule oscillations.

Modeling large-scale dynamic processes in the cell: polarization, waves, and division

Models of the collective behavior of proteins in cells: tubulin, actin and motor proteins

Molecular modeling of the cytoskeleton

Multisite Ion Models That Improve Coordination and Free Energy Calculations in Molecular Dynamics Simulations

Multivariate analyses of amyloid-beta oligomer populations indicate a connection between pore formation and cytotoxicity

Mutations in alpha-tubulin confer dinitroaniline resistance at a cost to microtubule function

Myo1c binds phosphoinositides through a putative pleckstrin homology domain

Nanoparticle pharmacokinetic profiling in vivo using magnetic resonance imaging

Neurodegeneration mutations in dynactin impair dynein-dependent nuclear migration.

New insights into mechanism and regulation of actin capping protein.

Novel α-tubulin mutation disrupts neural development and tubulin proteostasis

Nucleotide effects on the structure and dynamics of actin

Orthogonal trajectories and analytical solutions of the van der Pol equation without forcing

Overlapping and distinct functions for cofilin, coronin and Aip1 in actin dynamics in vivo

Perturbations in Microtubule Mechanics from Tubulin Preparation

Pharmacokinetic modeling of tumor bioluminescence implicates efflux, and not influx, as the bigger hurdle in cancer drug therapy

Properties of Microtubules with Isotropic and Anisotropic Mechanics

Real-time shape approximation and fingerprinting of single proteins using a nanopore

Sampling and statistics in biomolecular simulations

Scaling relations in the spherically symmetric Landau—Ginzburg model and a possible connection with self-organized criticality

Single-particle characterization of Aβ oligomers in solution

Stochastic data analysis for the assembly and disassembly of microtubules in vitro

Structure/function analysis of the interaction of phosphatidylinositol 4,5-bisphosphate with actin-capping protein: implications for how capping protein binds the actin filament

Synthesis of chondramide A analogues with modified β-tyrosine and their biological evaluation

Synthetic chondramide A analogues stabilize filamentous actin and block invasion by Toxoplasma gondii ⬇️

Taxol allosterically alters the dynamics of the tubulin dimer and increases the flexibility of microtubules