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List of works by Giulia Taraboletti

45th annual meeting of the Italian Cancer Society. Bergamo, 9-12 November 2003.

scientific article

ADAMDEC1 Maintains a Growth Factor Signaling Loop in Cancer Stem Cells

scientific article published on 21 August 2019

ADAMTS13 Deficiency Shortens the Life Span of Mice With Experimental Diabetes

scientific article published on 05 July 2018

Abstract 198: The T3R domain of thrombospondin-1 delays tumor growth and improves tumor response to chemotherapy by remodeling the tumor vasculature

scholarly article

Alternative Vascularization Mechanisms in Tumor Resistance to Therapy

scientific article published in 2021

Anti-angiogenic, vascular-disrupting and anti-metastatic activities of vinflunine, the latest vinca alkaloid in clinical development

scientific article published on 14 September 2006

Antiangiogenic activity of trabectedin in myxoid liposarcoma: Involvement of host TIMP-1 and TIMP-2 and tumor thrombospondin-1

scientific article published on 19 June 2014

Antiangiogenic and antitumor activity of IDN 5390, a new taxane derivative

scientific article published on April 2002

Antiangiogenic and antivascular therapy for cancer.

scientific article

Antimetastatic and antiangiogenic activity of trabectedin in cutaneous melanoma

scientific article published on 01 April 2019

Aplidine, a new anticancer agent of marine origin, inhibits vascular endothelial growth factor (VEGF) secretion and blocks VEGF-VEGFR-1 (flt-1) autocrine loop in human leukemia cells MOLT-4.

scientific article published on January 2003

Bioavailability of VEGF in tumor-shed vesicles depends on vesicle burst induced by acidic pH.

scientific article

CCN-Based Therapeutic Peptides Modify Pancreatic Ductal Adenocarcinoma Microenvironment and Decrease Tumor Growth in Combination with Chemotherapy

scientific article published on 13 April 2020

CXCR4 on human endothelial cells can serve as both a mediator of biological responses and as a receptor for HIV-2.

scientific article

Cathepsin B mediates the pH-dependent proinvasive activity of tumor-shed microvesicles

scientific article published on May 2008

Cediranib combined with chemotherapy reduces tumor dissemination and prolongs the survival of mice bearing patient-derived ovarian cancer xenografts with different responsiveness to cisplatin

scientific article published on 17 July 2015

Current understanding of the thrombospondin-1 interactome.

scientific article published on 27 January 2014

Direct and allosteric inhibition of the FGF2/HSPGs/FGFR1 ternary complex formation by an antiangiogenic, thrombospondin-1-mimic small molecule

scientific article

ERK1-2 and p38 MAPK regulate MMP/TIMP balance and function in response to thrombospondin-1 fragments in the microvascular endothelium.

scientific article published in April 2004

Effect of alltrans-retinoic acid (ATRA) on the adhesive and motility properties of acute promyelocytic leukemia cells

scientific article published on 01 January 1997

Endothelin-1 induces an angiogenic phenotype in cultured endothelial cells and stimulates neovascularization in vivo.

scientific article published on November 2000

Enhancement of Metastatic Potential of Murine and Human Melanoma Cells by Laminin Receptor Peptide G: Attachment of Cancer Cells to Subendothelial Matrix as a Pathway for Hematogenous Metastasis

scientific article published on 01 February 1993

Expression levels of vascular endothelial growth factor, matrix metalloproteinases 2 and 9 and tissue inhibitor of metalloproteinases 1 and 2 in the plasma of patients with ovarian carcinoma

scientific article published on 01 September 2003

Expression of thrombospondin-1 by tumor cells in patient-derived ovarian carcinoma xenografts.

scientific article published on 15 June 2015

Fibroblast growth factor-2 binding to the thrombospondin-1 type III repeats, a novel antiangiogenic domain

scientific article

Gorham-Stout Syndrome: A Monocyte-Mediated Cytokine Propelled Disease

article

Hepatocyte growth factor (HGF) downregulates thrombospondin 1 (TSP-1) expression in thyroid papillary carcinoma cells

scientific article

IDN 5390: a new concept in taxane development

scientific article

Increased tumorigenicity and invasiveness of C6 rat glioma cells transfected with the human alpha-2,8 sialyltransferase cDNA.

scientific article published on January 1998

Inhibition of Angiogenesis and Murine Hemangioma Growth by Batimastat, a Synthetic Inhibitor of Matrix Metalloproteinases

scientific article published on 01 February 1995

Inhibition of SIRT2 potentiates the anti-motility activity of taxanes: implications for antineoplastic combination therapies.

scientific article

Integrating computational and chemical biology tools in the discovery of antiangiogenic small molecule ligands of FGF2 derived from endogenous inhibitors.

scientific article

Matrigel promotes retinoblastoma cell growth in vitro and in vivo

scientific article published in September 1992

Matrix metalloproteinases (MMP9 and MMP2) induce the release of vascular endothelial growth factor (VEGF) by ovarian carcinoma cells: implications for ascites formation.

scientific article published in September 2003

Membrane fluidity affects tumor-cell motility, invasion and lung-colonizing potential

scientific article published on 01 October 1989

Mesothelial cells induce the motility of human ovarian carcinoma cells

scientific article published on 01 January 1999

Modulation of laminin receptor expression by estrogen and progestins in human breast cancer cell lines

scientific article published on 01 May 1989

Molecular basis of the antiangiogenic action of rosmarinic acid, a natural compound targeting Fibroblast Growth Factor-2/FGFR interactions

scientific article published on 25 September 2020

Non-peptidic thrombospondin-1 mimics as fibroblast growth factor-2 inhibitors: an integrated strategy for the development of new antiangiogenic compounds

scientific article

Pentraxin 3 regulates synaptic function by inducing AMPA receptor clustering via ECM remodeling and β1-integrin

scientific article published on 05 November 2018

Pharmacokinetics and antineoplastic activity of galectin-1-targeting OTX008 in combination with sunitinib.

scientific article published on 24 August 2013

Posttranscriptional stimulation of endothelial cell matrix metalloproteinases 2 and 1 by endothelioma cells.

scientific article published on August 2000

Potential antagonism of tubulin-binding anticancer agents in combination therapies.

scientific article

Preclinical development of metalloproteasis inhibitors in cancer therapy.

scientific article

Proliferative and migratory responses of murine microvascular endothelial cells to granulocyte‐colony‐stimulating factor ⬇️

scientific article published on April 1, 1993

Reduced expression of the ROCK inhibitor Rnd3 is associated with increased invasiveness and metastatic potential in mesenchymal tumor cells

scientific article

Sequence dependent antitumour efficacy of the vascular disrupting agent ZD6126 in combination with paclitaxel.

scientific article published on 11 September 2007

Shedding of the matrix metalloproteinases MMP-2, MMP-9, and MT1-MMP as membrane vesicle-associated components by endothelial cells

scientific article published on February 2002

Snail levels control the migration mechanism of mesenchymal tumor cells.

scientific article published on 30 May 2016

Soluble stroma-related biomarkers of pancreatic cancer.

scientific article

Targeting angiogenesis with compounds from the extracellular matrix

scientific article published on 17 August 2011

Targeting tumor angiogenesis with TSP-1-based compounds: rational design of antiangiogenic mimetics of endogenous inhibitors ⬇️

scientific article published on November 1, 2010

The calcium-binding type III repeats domain of thrombospondin-2 binds to fibroblast growth factor 2 (FGF2)

scientific article published on 30 August 2018

The metalloproteinase ADAMDEC1 maintains a novel growth factor signalling loop in glioblastoma cancer stem cells ⬇️

scholarly article

The tyrosine kinase inhibitor E-3810 combined with paclitaxel inhibits the growth of advanced-stage triple-negative breast cancer xenografts

scientific article

Thrombospondin 1 as a scavenger for matrix-associated fibroblast growth factor 2

scientific article published on 28 August 2003

Thrombospondin-1 as a Paradigm for the Development of Antiangiogenic Agents Endowed with Multiple Mechanisms of Action.

scientific article

Thrombospondin-1 inhibits Kaposi's sarcoma (KS) cell and HIV-1 Tat-induced angiogenesis and is poorly expressed in KS lesions

article

Thrombospondin-1 is part of a Slug-independent motility and metastatic program in cutaneous melanoma, in association with VEGFR-1 and FGF-2.

scientific article published on 13 October 2014

Thrombospondin-1 promotes mesenchymal stromal cell functions via TGFβ and in cooperation with PDGF.

scientific article published on 15 March 2016

Thrombospondins in bone remodeling and metastatic bone disease

scientific article published on 16 September 2020

Tumor-derived chemotactic factor(s) from human ovarian carcinoma: evidence for a role in the regulation of macrophage content of neoplastic tissues.

scientific article

Tumor-host interaction in the optimization of paclitaxel-based combination therapies with vascular targeting compounds

scientific article published on December 2007

Vascular disrupting activity of tubulin-binding 1,5-diaryl-1H-imidazoles

scientific article

Vascular endothelial growth factor c promotes ovarian carcinoma progression through paracrine and autocrine mechanisms

scientific article

Vascular endothelial growth factor stimulates organ-specific host matrix metalloproteinase-9 expression and ovarian cancer invasion

scientific article published in April 2008

Vascular-targeting activity of ZD6126, a novel tubulin-binding agent.

scientific article published in April 2003

p73 overexpression increases VEGF and reduces thrombospondin-1 production: implications for tumor angiogenesis

scientific article published on 01 November 2001

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