Search filters

List of works by Filippo Belardelli

2–5A synthetase activity does not increase in interferon-resistant friend leukemia cell variants treated with α/β interferon despite the presence of high-affinity interferon receptor sites ⬇️

scientific article published on March 1, 1983

A good manufacturing practice method to ex vivo expand natural killer cells for clinical use.

scientific article

A multidisciplinary study using in vivo tumor models and microfluidic cell-on-chip approach to explore the cross-talk between cancer and immune cells

scientific article published on 6 March 2014

A type I IFN-dependent pathway induced by Schistosoma mansoni eggs in mouse myeloid dendritic cells generates an inflammatory signature

scientific article published on March 2004

APC activation by IFN-alpha decreases regulatory T cell and enhances Th cell functions

scientific article published on 28 April 2010

Accreditation for excellence of cancer research institutes: recommendations from the Italian Network of Comprehensive Cancer Centers

scientific article

Adoptive transfer of an anti-MART-12735-specific CD8+ T cell clone leads to immunoselection of human melanoma antigen-loss variants in SCID mice

scientific article published on 01 February 2003

Alterations of lipid composition in Friend leukemia cell tumors in mice treated with tumor necrosis factor-alpha.

scientific article published on January 1990

Anti-tumor effects of interferon in mice injected with interferon-sensitive and interferon-resistant Friend erythroleukemia cells. VIII. Role of the immune system in the inhibition of visceral metastases

scientific article published on 01 September 1990

Anti-tumor effects of interferon in mice injected with interferon-sensitive and interferon-resistant Friend leukemia cells. VI. Adjuvant therapy after surgery in the inhibition of liver and spleen metastases

scientific article published on 01 June 1987

Anti-tumor effects of interferon in mice injected with interferon-sensitive and interferon-resistant friend leukemia cells. IV. Definition of optimal treatment regimens.

scientific article

Anti-tumor effects of interferon in mice injected with interferon-sensitive and interferon-resistant friend leukemia cells. V. Comparisons with the action of tumor necrosis factor

scientific article published on 01 November 1986

Anti-tumor effects of interleukin-2 and interleukin-1 in mice transplanted with different syngeneic tumors.

scientific article

Antitumor Effects of Epidrug/IFNα Combination Driven by Modulated Gene Signatures in Both Colorectal Cancer and Dendritic Cells.

scientific article published on 14 June 2017

Antitumor effects of interferon in mice injected with interferon-sensitive and interferon-resistant Friend leukemia cells. I.

scientific article

Antitumor effects of interferon in mice injected with interferon-sensitive and interferon-resistant Friend leukemia cells. II. Role of host mechanisms.

scientific article

Antitumor effects of interferon in mice injected with interferon-sensitive and interferon-resistant Friend leukemia cells. III. Inhibition of growth and necrosis of tumors implanted subcutaneously.

scientific article

Antiviral effect of bovine lactoferrin saturated with metal ions on early steps of human immunodeficiency virus type 1 infection.

scientific article

Apicidin and docetaxel combination treatment drives CTCFL expression and HMGB1 release acting as potential antitumor immune response inducers in metastatic breast cancer cells.

scientific article

Application of OECI accreditation program to cancer institutes of the Alleanza Contro il Cancro Italian Network: a special project supported by the Italian Ministry of Health.

scientific article published on 30 December 2015

Biologic and biochemical differences between in vitro and in vivo passaged Friend erythroleukemia cells. I. Tumorigenicity and capacity to metastasize

scientific article published on 01 September 1984

Biologic and biochemical differences between in vitro and in vivo passaged Friend erythroleukemia cells. II. Changes in cell surface glycoproteins associated with a highly malignant phenotype

scientific article published on 01 September 1984

CC chemokine ligand 2 down-modulation by selected Toll-like receptor agonist combinations contributes to T helper 1 polarization in human dendritic cells.

scientific article published on 22 May 2009

CD2+/CD14+ monocytes rapidly differentiate into CD83+ dendritic cells

scientific article published on 01 February 2003

Cancer cell-autonomous contribution of type I interferon signaling to the efficacy of chemotherapy

scientific article

Chemo-immunotherapy induces tumor regression in a mouse model of spontaneous mammary carcinogenesis

scientific article published on 28 July 2016

Chemotherapy enhances vaccine-induced antitumor immunity in melanoma patients.

scientific article published in January 2009

Cholera toxin and its B subunit inhibit interferon effects on virus production and erythroid differentiation of Friend leukemia cells.

scientific article published in November 1980

Concanavalin A-induced inhibition of abrin and ricin activity parallels with a decrease of the number of toxin-binding uptake-elution cycles

scientific article published on 01 December 1982

Concomitant detection of IFNα signature and activated monocyte/dendritic cell precursors in the peripheral blood of IFNα-treated subjects at early times after repeated local cytokine treatments ⬇️

scientific article

Correlation between the sensitivity or resistance to IL-2 and the response to cyclophosphamide of 4 tumors transplantable in the same murine host.

scientific article published in July 1995

Corrigendum to “MHV-68 producing mIFNα1 is severely attenuated in vivo and effectively protects mice against challenge with wt MHV-68” [Vaccine 29 (2011) 3935–3944]

scholarly article published in Vaccine

Cross talk between cancer and immune cells: exploring complex dynamics in a microfluidic environment

scientific article published on 30 October 2012

Cyclic AMP-mediated inhibition of vesicular stomatitis virus and herpes simplex virus replication in mouse macrophage-like cells.

scientific article published in November 1992

Cyclophosphamide induces a type I interferon-associated sterile inflammatory response signature in cancer patients' blood cells: implications for cancer chemoimmunotherapy.

scientific article published on 12 June 2013

Cyclophosphamide synergizes with type I interferons through systemic dendritic cell reactivation and induction of immunogenic tumor apoptosis

scientific article

Cytokines as a link between innate and adaptive antitumor immunity.

scientific article

Cytokines as natural adjuvants for vaccines: where are we now?

scientific article published on 01 August 2002

Cytokines, dendritic cells and immunological rejection

scientific article published on 03 December 2007

Dacarbazine treatment before peptide vaccination enlarges T-cell repertoire diversity of melan-a-specific, tumor-reactive CTL in melanoma patients.

scientific article published on 7 September 2010

Dendritic cells and cytokines in immune rejection of cancer.

scientific article published on 03 December 2007

Development of a pilot project on data sharing among partners of the Italian Hub of Population Biobanks (HIBP): association between lipid profile and socio-demographic variables

scientific article

Differentiation of monocyte-derived dendritic cells is associated with upregulation and activation of Rac-1 small GTPase

scientific article published on 08 May 2006

Dual role of the HIV-1 vpr protein in the modulation of the apoptotic response of T cells.

scientific article published in September 2000

Effectiveness of mouse interferon alpha/beta compared to single-agent chemotherapy in increasing survival time of mice after intravenous inoculation of Friend erythroleukemia cells

scientific article published on 01 March 1988

Effects of different biological response modifiers on interferon expression in bacterial lipopolysaccharide (LPS)-responsive and LPS-hyporesponsive mouse peritoneal macrophages.

scientific article published in November 1990

Eighth annual meeting of the Italian network for tumor biotherapy (NIBIT), Siena, October 7-9, 2010.

scientific article published on 24 March 2011

Endogenous CCL2 (monocyte chemotactic protein-1) modulates human immunodeficiency virus type-1 replication and affects cytoskeleton organization in human monocyte-derived macrophages

scientific article published on 12 June 2003

Endogenous type I interferons as a defense against tumors.

scientific article

Epstein-Barr virus infection induces miR-21 in terminally differentiated malignant B cells

scientific article published on 4 March 2015

European Code against Cancer 4th Edition: 12 ways to reduce your cancer risk

scientific article published on 9 July 2015

Evaluation of the effects of human leukocyte IFN-α on the immune response to the HBV vaccine in healthy unvaccinated individuals

article

Exploitation of the propulsive force of chemotherapy for improving the response to cancer immunotherapy.

scientific article published on 03 December 2011

Exploiting a new strategy to induce immunogenic cell death to improve dendritic cell-based vaccines for lymphoma immunotherapy

scientific article published on 31 July 2017

Exploiting dendritic cells in the development of cancer vaccines

scientific article published on 04 October 2013

Expression of CCR-7, MIP-3beta , and Th-1 chemokines in type I IFN-induced monocyte-derived dendritic cells: importance for the rapid acquisition of potent migratory and functional activities

scientific article published on 01 November 2001

Expression of interferon genes in murine macrophages: Possible role of endogenous interferon in the modulation of cell differentiation ⬇️

scientific article published on February 1, 1991

Extracellular matrix remodelling in a murine mammary adenocarcinoma transfected with the interferon-alpha 1 gene

scientific article published on 01 January 1997

High-affinity binding of 125I-labeled mouse interferon to a specific cell surface receptor. IV. Mouse gamma interferon and cholera toxin do not compete for the common receptor site of alpha / beta interferon.

scientific article

Human immunodeficiency virus type 1 gp120 and other activation stimuli are highly effective in triggering alpha interferon and CC chemokine production in circulating plasmacytoid but not myeloid dendritic cells.

scientific article

Human immunodeficiency virus type 1 gp120 induces abnormal maturation and functional alterations of dendritic cells: a novel mechanism for AIDS pathogenesis.

scientific article published on September 2004

ICSBP is critically involved in the normal development and trafficking of Langerhans cells and dermal dendritic cells

article

ICSBP is essential for the development of mouse type I interferon-producing cells and for the generation and activation of CD8alpha(+) dendritic cells

scientific article

ICSBP/IRF-8 differentially regulates antigen uptake during dendritic-cell development and affects antigen presentation to CD4+ T cells

scientific article

IFN-alpha 1 gene transfection completely abolishes the tumorigenicity of murine B16 melanoma cells in allogeneic DBA/2 mice and decreases their tumorigenicity in syngeneic C57BL/6 mice

scientific article published on 01 January 1995

IFN-alpha promotes the rapid differentiation of monocytes from patients with chronic myeloid leukemia into activated dendritic cells tuned to undergo full maturation after LPS treatment

scientific article

IFN-α as a vaccine adjuvant: recent insights into the mechanisms and perspectives for its clinical use.

scientific article published on April 2011

IFN-α boosts epitope cross-presentation by dendritic cells via modulation of proteasome activity.

scientific article published on 21 October 2010

IFN-α enhances cross-presentation in human dendritic cells by modulating antigen survival, endocytic routing, and processing.

scientific article published on 19 December 2011

IFN-α potentiates the direct and immune-mediated antitumor effects of epigenetic drugs on both metastatic and stem cells of colorectal cancer

scientific article published on 25 March 2016

IFN-α regulates Blimp-1 expression via miR-23a and miR-125b in both monocytes-derived DC and pDC.

scientific article

IFN-α-conditioned dendritic cells are highly efficient in inducing cross-priming CD8+ T cells against exogenous viral antigens

scientific article published on 01 August 2006

IFN-γ Expression in Macrophages and Its Possible Biological Significance ⬇️

scientific article published on 01 June 1998

IL-15 is expressed by dendritic cells in response to type I IFN, double-stranded RNA, or lipopolysaccharide and promotes dendritic cell activation

scientific article (publication date: August 2001)

IL-2 induces expression and secretion of IFN-γ in murine peritoneal macrophages

scientific article published on 10 June 2005

IRF-1 deficiency skews the differentiation of dendritic cells toward plasmacytoid and tolerogenic features.

scientific article published on 11 September 2006

IRF-8 controls melanoma progression by regulating the cross talk between cancer and immune cells within the tumor microenvironment.

scientific article published on December 2012

Immune-based mechanisms of cytotoxic chemotherapy: implications for the design of novel and rationale-based combined treatments against cancer ⬇️

scientific article published on June 21, 2013

Immunization of stage IV melanoma patients with Melan-A/MART-1 and gp100 peptides plus IFN-alpha results in the activation of specific CD8(+) T cells and monocyte/dendritic cell precursors.

scientific article published in May 2006

Impaired myelopoiesis in mice devoid of interferon regulatory factor 1.

scientific article published in November 2004

Impairment of human immunodeficiency virus type 1 (HIV-1) entry into Jurkat T cells by constitutive expression of the HIV-1 vpr protein: role of CD4 down-modulation

scientific article published on November 2000

Importance of cyclophosphamide-induced bystander effect on T cells for a successful tumor eradication in response to adoptive immunotherapy in mice

scientific article published on January 1998

Importance of interferon alpha in the resistance of allogeneic C57B1/6 mice to the multiplication of Friend erythroleukemia cells in the liver

scientific article published on 01 February 1990

Induction of both CD8+ and CD4+ T-cell-mediated responses in colorectal cancer patients by colon antigen-1.

scientific article published on 30 October 2008

Infection of HHV-8+ primary effusion lymphoma cells with a recombinant Epstein-Barr virus leads to restricted EBV latency, altered phenotype, and increased tumorigenicity without affecting TCL1 expression.

scientific article published on 11 September 2003

Inhibition of angiogenesis and vascular tumor growth by interferon-producing cells: A gene therapy approach

scientific article

Inhibition of animal virus production by means of translation inhibitors unable to penetrate normal cells.

scientific article published in October 1980

Inhibition of human immunodeficiency virus (HIV-1) infection in human peripheral blood leucocytes-SCID reconstituted mice by rapamycin

scientific article

Inhibition of lung colonisation of a mouse mammary carcinoma by therapeutic vaccination with interferon-alpha gene-transduced tumor cells

scientific article published in 1998

Inhibition of the constitutive and induced IFN-beta production by IL-4 and IL-10 in murine peritoneal macrophages

scientific article published on 01 November 2000

Inhibition of transcription and translation of globin messenger RNA in dimethyl sulfoxide-stimulated Friend erythroleukemic cells treated with interferon ⬇️

scientific article published on May 1, 1977

Inhibition of vaginal transmission of HIV-1 in hu-SCID mice by the non-nucleoside reverse transcriptase inhibitor TMC120 in a gel formulation

article

Interaction of IFN alpha/beta with host cells essential to the early inhibition of Friend erythroleukemia visceral metastases in mice.

scientific article published on May 1994

Interferon fundamentals: a tribute to the scientific vision of G B Rossi. Editorial.

scientific article published on 26 December 2014

Interferon gamma upregulates its own gene expression in mouse peritoneal macrophages.

scientific article published on May 1994

Interferon inhibits dimethyl sulphoxide-induced erythroid differentiation of Friend leukaemia cells

scientific article published on 01 May 1977

Interferon regulatory factor 8-deficiency determines massive neutrophil recruitment but T cell defect in fast growing granulomas during tuberculosis

scientific article published in 2013

Interferon treatment markedly inhibits the development of tumor metastases in the liver and spleen and increases survival time of mice after intravenous inoculation of Friend erythroleukemia cells

scientific article published on 01 January 1988

Interferon-alpha and cancer: mechanisms of action and new perspectives of clinical use.

scientific article

Interferon-alpha/beta in virus-induced mouse mammary carcinogenesis: effects on the spontaneous process and on the progression of transplanted pre-neoplastic lesions

scientific article

Interferon-α as antiviral and antitumor vaccine adjuvants: mechanisms of action and response signature.

scientific article published on 10 April 2012

Interferon-α-conditioned human monocytes combine a Th1-orienting attitude with the induction of autologous Th17 responses: role of IL-23 and IL-12.

scientific article

Interleukin-1 beta induces tumor necrosis and early morphologic and metabolic changes in transplantable mouse tumors. Similarities with the anti-tumor effects of tumor necrosis factor alpha or beta

scientific article published on 01 July 1989

International Accreditation of Cancer Centres of Italian Network of Alleanza contro il Cancro: introductory remarks.

scientific article published on 30 December 2015

International meeting "Immunotherapy of cancer: challenges and needs".

scientific article published on 28 November 2006

International meeting on cancer vaccines: how can we enhance efficacy of therapeutic vaccines?

scientific article published in September 2004

Intratumoral injection of IFN-alpha dendritic cells after dacarbazine activates anti-tumor immunity: results from a phase I trial in advanced melanoma

scientific article published on 2 May 2015

LOX-1 as a natural IFN- -mediated signal for apoptotic cell uptake and antigen presentation in dendritic cells

scientific article published on 15 December 2009

Lenalidomide improves the therapeutic effect of an interferon-α-dendritic cell-based lymphoma vaccine

scientific article published on 16 October 2019

Loss of type I IFN receptors and impaired IFN responsiveness during terminal maturation of monocyte-derived human dendritic cells.

scientific article

MHV-68 producing mIFNα1 is severely attenuated in vivo and effectively protects mice against challenge with wt MHV-68.

scientific article published on 8 April 2011

Modulations of glycerophosphorylcholine and phosphorylcholine in Friend erythroleukemia cells upon in vitro-induced erythroid differentiation: a 31P NMR study.

scientific article published on October 1984

Monocyte/macrophage-derived CC chemokines and their modulation by HIV-1 and cytokines: a complex network of interactions influencing viral replication and AIDS pathogenesis.

scientific article

NK Cell Activation in the Antitumor Response Induced by IFN-α Dendritic Cells Loaded with Apoptotic Cells from Follicular Lymphoma Patients.

scientific article published on 29 June 2016

Need for global action for cancer control

scientific article published on 01 September 2008

Ninth annual meeting of the Italian Network for Tumor Biotherapy (NIBIT), Siena, Italy, October 19-22, 2011: New perspectives in the immunotherapy of cancer

scientific article published on 27 June 2012

Opposite regulatory effects of IFN- and IL-3 on C-type lectin receptors, antigen uptake, and phagocytosis in human macrophages

scientific article published on 09 September 2013

Pertussis toxin B-oligomer inhibits HIV infection and replication in hu-PBL-SCID mice

article

Phosphatidylcholine-specific phospholipase C activation is required for CCR5-dependent, NF-kB-driven CCL2 secretion elicited in response to HIV-1 gp120 in human primary macrophages

scientific article

Potent immune response against HIV-1 and protection from virus challenge in hu-PBL-SCID mice immunized with inactivated virus-pulsed dendritic cells generated in the presence of IFN-alpha

scientific article

Recent advances on the immunomodulatory effects of IFN-alpha: implications for cancer immunotherapy and autoimmunity.

scientific article published on April 2010

Recombinant interferon-alpha2b improves immune response to hepatitis B vaccination in haemodialysis patients: results of a randomised clinical trial

scientific article published on 25 July 2009

Role of Interferon Regulatory Factor 1 in Governing Treg Depletion, Th1 Polarization, Inflammasome Activation and Antitumor Efficacy of Cyclophosphamide.

scientific article published on 4 October 2017

Role of cytokines in GVL (ESb lymphoma) and GVHD after adoptive transfer of allogeneic T lymphocytes in mice

scientific article published on 01 September 1998

Role of endogenous interferon and LPS in the immunomodulatory effects of bovine lactoferrin in murine peritoneal macrophages

scientific article published on 02 May 2007

Role of interferons in the restriction of HIV replication in human monocytes/macrophages.

scientific article published on October 1994

Role of the cytokine environment and cytokine receptor expression on the generation of functionally distinct dendritic cells from human monocytes

scientific article published on 01 March 2008

Role of type I interferon in inducing a protective immune response: perspectives for clinical applications

scientific article

Selective alteration of the turnover of interferon beta mRNA in peritoneal macrophages from LPS-hyporesponsive mice and its role in the defective expression of spontaneous interferon.

scientific article

Sensitized T lymphocytes render DBA/2 beige mice responsive to IFN alpha/beta therapy of Friend erythroleukemia visceral metastases

scientific article published on 01 May 1993

Seventh annual meeting of the Italian Network for Tumor Biotherapy (NIBIT), Siena, 1-3 October 2009.

scientific article published on 5 March 2010

Sixth annual meeting of the Italian network for tumor biotherapy (NIBIT), Siena, 16-18 October 2008.

scientific article published on 28 March 2009

Spin-lattice relaxation in murine tumors after in vivo treatment with interferon alpha/beta or tumor necrosis factor alpha

scientific article published on 01 January 1992

Synergistic anti-tumor effects of combined IL-1/IFN-alpha/beta therapy in mice injected with metastatic Friend erythroleukemia cells

scientific article published on 01 September 1991

TRAIN: Training through Research Application Italian Initiative

article

Tenth annual meeting of the Italian Network for Tumor Biotherapy (NIBIT), SIENA, Italy, November 5-7, 2012.

scientific article

The HIV-1 vpr protein acts as a negative regulator of apoptosis in a human lymphoblastoid T cell line: possible implications for the pathogenesis of AIDS

scientific article

The Italian Hub of Population Biobanks as a Potential Tool for Improving Public Health Stewardship ⬇️

scientific article (publication date: June 2013)

The Italian Network for Tumor Biotherapy (NIBIT): getting together to push the field forward.

scientific article published on 12 February 2008

The biological relevance of polykaryons in the immune response ⬇️

scientific article published on November 1, 1997

The essential role of endogenous IFN alpha/beta in the anti-metastatic action of sensitized T lymphocytes in mice injected with Friend erythroleukemia cells.

scientific article published on November 1995

The natural alliance between type I interferon and dendritic cells and its role in linking innate and adaptive immunity.

scientific article

Tumor necrosis factor alpha induces early morphologic and metabolic alterations in Friend leukemia cell tumors and fibrosarcomas in mice

scientific article published on 01 October 1988

Type I IFN as a natural adjuvant for a protective immune response: lessons from the influenza vaccine model

scientific article published on 01 July 2002

Type I IFN is a powerful mucosal adjuvant for a selective intranasal vaccination against influenza virus in mice and affects antigen capture at mucosal level.

scientific article

Type I IFN regulate DC turnover in vivo.

scientific article

Type I IFNs control antigen retention and survival of CD8α(+) dendritic cells after uptake of tumor apoptotic cells leading to cross-priming

scientific article published on 25 March 2011

Type I interferon as a powerful adjuvant for monocyte-derived dendritic cell development and activity in vitro and in Hu-PBL-SCID mice.

scientific article

Type I interferon gene transfer sensitizes melanoma cells to apoptosis via a target activity on mitochondrial function

scientific article

Type I interferons as regulators of human antigen presenting cell functions.

scientific article published on 26 May 2014

Type I interferons produced by dendritic cells promote their phenotypic and functional activation

scientific article published on 01 May 2002

Type i interferons potently enhance humoral immunity and can promote isotype switching by stimulating dendritic cells in vivo.

scientific article published in April 2001

U937-SCID mouse xenografts: a new model for acute in vivo HIV-1 infection suitable to test antiviral strategies

article

Unraveling cancer chemoimmunotherapy mechanisms by gene and protein expression profiling of responses to cyclophosphamide

scientific article published on 28 March 2011

Vaccination with inactivated murine gammaherpesvirus 68 strongly limits viral replication and latency and protects type I IFN receptor knockout mice from a lethal infection.

scientific article published on March 2004

Vaginal transmission of HIV-1 in hu-SCID mice: a new model for the evaluation of vaginal microbicides.

scientific article published in November 2001

Wheat germ agglutinin-binding protein changes in highly malignant Friend leukemia cells metastasizing to the liver

scientific article published on 01 September 1988

Paulina is supported by:

About Paulina

Help