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List of works by Hiroshi Shimizu

13C metabolic flux analysis clarifies distinct metabolic phenotypes of cancer cell spheroid mimicking tumor hypoxia

scientific article published in 2022

Application of adaptive laboratory evolution to overcome a flux limitation in an Escherichia coli production strain.

scientific article published on 19 February 2018

Assessment of Protein Content and Phosphorylation Level in Synechocystis sp. PCC 6803 under Various Growth Conditions Using Quantitative Phosphoproteomic Analysis

scientific article published on 06 August 2020

Combinatorial deletions of glgC and phaCE enhance ethanol production in Synechocystis sp. PCC 6803.

scientific article published on 27 September 2016

Comparative Targeted Proteomics of the Central Metabolism and Photosystems in SigE Mutant Strains of Synechocystis sp. PCC 6803

scientific article published on 01 May 2018

Conversion of Mevalonate to Isoprenol Using Light Energy in <i>Escherichia coli</i> without Consuming Sugars for ATP Supply

scientific article published in 2022

Effect of precise control of flux ratio between the glycolytic pathways on mevalonate production in Escherichia coli

scientific article published on 04 February 2019

Enhancement of 1,5-diaminopentane production in a recombinant strain of Corynebacterium glutamicum by Tween 40 addition

scientific article published in January 2016

GC-MS/MS survey of collision-induced dissociation of tert-butyldimethylsilyl-derivatized amino acids and its application to (13)C-metabolic flux analysis of Escherichia coli central metabolism

scientific article published on 24 June 2016

Identification of alcohol stress tolerance genes of Synechocystis sp. PCC 6803 using adaptive laboratory evolution.

scientific article published on 20 December 2017

Light-inducible flux control of triosephosphate isomerase on glycolysis in Escherichia coli

scientific article published on 02 September 2019

Metabolic Adaptation to Nutritional Stress in Human Colorectal Cancer.

scientific article published on 07 December 2016

Metabolic engineering of isopropyl alcohol-producing Escherichia coli strains with 13 C-metabolic flux analysis.

scientific article

Metabolic pathway design for growth-associated phenylalanine production using synthetically designed mutualism

scientific article published in 2022

Metabolic pathway engineering for the non-growth-associated succinate production in Escherichia coli based on flux solution space

scientific article published in 2022

Metabolome analysis of Saccharomyces cerevisiae and optimization of culture medium for S-adenosyl-L-methionine production

scientific article

Mutations in hik26 and slr1916 lead to high-light stress tolerance in Synechocystis sp. PCC6803

scientific article published on 16 March 2021

OpenMebius: an open source software for isotopically nonstationary 13C-based metabolic flux analysis.

scientific article

Prediction of Rate-Limiting Reactions for Growth-Associated Production Using a Constraint-Based Approach

scientific article published on 11 July 2019

Recent advances in metabolic engineering–integration of in silico design and experimental analysis of metabolic pathways

scientific article published in 2021

Sugar phosphate analysis with baseline separation and soft ionization by gas chromatography-negative chemical ionization-mass spectrometry improves flux estimation of bidirectional reactions in cancer cells

scientific article published on 01 September 2018

Targeted proteome analysis of microalgae under high-light conditions by optimized protein extraction of photosynthetic organisms

scientific article published on 28 September 2018

Transcriptome analysis of the cyanobacterium Synechocystis sp. PCC 6803 and mechanisms of photoinhibition tolerance under extreme high light conditions

scientific article published on 19 June 2018

Transomics data-driven, ensemble kinetic modeling for system-level understanding and engineering of the cyanobacteria central metabolism

scientific article published on 08 January 2019