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List of works by Christopher E. Rudd

A new perspective in cancer immunotherapy: PD-1 on myeloid cells takes center stage in orchestrating immune checkpoint blockade

scientific article published on 01 January 2020

ADAP-SLP-76 binding differentially regulates supramolecular activation cluster (SMAC) formation relative to T cell-APC conjugation

scientific journal article

Adaptor SKAP-55 binds p21 activating exchange factor RasGRP1 and negatively regulates the p21-ERK pathway in T-cells

scientific article

Aiming for the Sweet Spot: Glyco-Immune Checkpoints and γδ T Cells in Targeted Immunotherapy ⬇️

journal article from 'Frontiers in Immunology' published in 2020

Altered proximal T cell receptor (TCR) signaling in human CD4+CD25+ regulatory T cells

scientific article

An essential role for SKAP-55 in LFA-1 clustering on T cells that cannot be substituted by SKAP-55R

scientific article

Association of T cell antigen CD7 with type II phosphatidylinositol-4 kinase, a key component in pathways of inositol phosphate turnover

scientific article (publication date: 2003)

CD28 and CTLA-4 coreceptor expression and signal transduction

scientific article (publication date: May 2009)

CD45 ligation expands Tregs by promoting interactions with DCs

scientific article

CEACAM1 regulates TIM-3-mediated tolerance and exhaustion

scientific journal article

CTLA-4 activation of phosphatidylinositol 3-kinase (PI 3-K) and protein kinase B (PKB/AKT) sustains T-cell anergy without cell death

scientific article

CTLA-4 negative signaling via lipid rafts: A new perspective

scientific article

CTLA-4 trafficking and surface expression

scientific article

CTLA-4 up-regulation of lymphocyte function-associated antigen 1 adhesion and clustering as an alternate basis for coreceptor function

scientific article

Cutting Edge: Regulator of G protein signaling-1 selectively regulates gut T cell trafficking and colitic potential

scientific article

Cutting edge: CTLA-4 (CD152) differentially regulates mitogen-activated protein kinases (extracellular signal-regulated kinase and c-Jun N-terminal kinase) in CD4+ T cells from receptor/ligand-deficient mice

scientific article

Decreased progenitor TCF1 + T-cells correlate with COVID-19 disease severity

scientific article published in 2024

Dynamics of subsynaptic vesicles and surface microclusters at the immunological synapse

scientific article

Glycogen Synthase Kinase 3 Inactivation Drives T-bet-Mediated Downregulation of Co-receptor PD-1 to Enhance CD8(+) Cytolytic T Cell Responses

scientific article published in February 2016

Glycogen synthase kinase 3 (GSK-3) controls T-cell motility and interactions with antigen presenting cells

scientific article published on 18 March 2020

Hematopoietic Adaptors in T-Cell Signaling: Potential Applications to Transplantation ⬇️

scientific article published on October 1, 2003

How the Discovery of the CD4/CD8-p56lck Complexes Changed Immunology and Immunotherapy ⬇️

journal article from 'Frontiers in Cell and Developmental Biology' published in 2021

Immune adaptor ADAP in T cells regulates HIV-1 transcription and cell-cell viral spread via different co-receptors ⬇️

scientific article

Immune adaptor protein SKAP1 (SKAP-55) forms homodimers as mediated by the N-terminal region

scientific article published on 06 December 2018

Independent CD28 signaling via VAV and SLP-76: a model for in trans costimulation

scientific article

Murine regulatory T cells differ from conventional T cells in resisting the CTLA-4 reversal of TCR stop-signal ⬇️

scientific article published on October 9, 2012

Phosphatidylinositol 3-kinase p85 adaptor function in T-cells. Co-stimulation and regulation of cytokine transcription independent of associated p110.

scientific article

Pillars article: the CD4 receptor is complexed in detergent lysates to a protein-tyrosine kinase (pp58) from human T lymphocytes. 1988 ⬇️

scientific article published on September 1, 2010

Protein tyrosine phosphorylation in T cell signaling

scientific article

Regulation and function of SKAP-55 non-canonical motif binding to the SH3c domain of adhesion and degranulation-promoting adaptor protein

scientific article

Reversal of the TCR stop signal by CTLA-4

scientific article

SH2 domain containing leukocyte phosphoprotein of 76-kDa (SLP-76) feedback regulation of ZAP-70 microclustering

scientific article

SKAP-55 regulates integrin adhesion and formation of T cell-APC conjugates

scientific article

SLP-76-ADAP adaptor module regulates LFA-1 mediated costimulation and T cell motility

scientific article

Signalling scaffolds and adaptors in T-cell immunity

scientific article

Ubc9 Interacts with and SUMOylates the TCR Adaptor SLP-76 for NFAT Transcription in T Cells

scientific article published on 30 October 2019

Unifying concepts in CD28, ICOS and CTLA4 co-receptor signalling

scientific article (publication date: July 2003)

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