Search filters

List of works by María J. Alonso

12. Biodegradable polymer nanoparticles as protein delivery systems

scholarly article by Noemi Csaba & María J. Alonso published September 2014 in Journal of Controlled Release

A Potential Nanomedicine Consisting of Heparin-Loaded Polysaccharide Nanocarriers for the Treatment of Asthma

scholarly article by Felipe A. Oyarzun-Ampuero et al published 23 November 2011 in Macromolecular Bioscience

A comparative study of chitosan and chitosan/cyclodextrin nanoparticles as potential carriers for the oral delivery of small peptides

scientific article published on 25 January 2010

A comparative study of curcumin-loaded lipid-based nanocarriers in the treatment of inflammatory bowel disease

scientific article published on 16 March 2016

A comparative study of the potential of solid triglyceride nanostructures coated with chitosan or poly(ethylene glycol) as carriers for oral calcitonin delivery.

scientific article published in May 2005

A multifunctional drug nanocarrier for efficient anticancer therapy

scientific article published on 08 December 2018

A new drug nanocarrier consisting of chitosan and hydoxypropylcyclodextrin.

scientific article published on 9 March 2006

A new drug nanocarrier consisting of polyarginine and hyaluronic acid

scientific article published on 27 April 2011

A new potential nano-oncological therapy based on polyamino acid nanocapsules

scientific article published in July 2013

A novel low molecular weight nanocomposite hydrogel formulation for intra-tumoural delivery of anti-cancer drugs

scientific article published on 25 April 2019

A novel system based on a poloxamer/PLGA blend as a tetanus toxoid delivery vehicle

scientific article published on 01 May 1999

A polymer/oil based nanovaccine as a single-dose immunization approach

scientific article

Aceclofenac-loaded poly-epsilon-caprolactone nanocapsules. Effect of coadjuvants on morphometrical properties and drug entrapment.

scientific article published in May 2000

Anti-tumor efficacy of chitosan-g-poly(ethylene glycol) nanocapsules containing docetaxel: anti-TMEFF-2 functionalized nanocapsules vs. non-functionalized nanocapsules

scientific article

Application of NMR spectroscopy to the characterization of PEG-stabilized lipid nanoparticles.

scientific article published in September 2004

Assessment of the permeability and toxicity of polymeric nanocapsules using the zebrafish model

scientific article published on 14 August 2017

Bilayer polymeric nanocapsules: A formulation approach for a thermostable and adjuvanted E. coli antigen vaccine

scientific article published on 12 July 2018

Biodegradable micro- and nanoparticles as long-term delivery vehicles for interferon-alpha.

scientific article published on March 2003

Biodegradable microspheres as controlled-release tetanus toxoid delivery systems.

scientific article

Biodistribution and lymph node retention of polysaccharide-based immunostimulating nanocapsules

scientific article published on 07 February 2014

Biodistribution of radiolabeled polyglutamic acid and PEG-polyglutamic acid nanocapsules.

scientific article published on 17 November 2016

Chitosan and chitosan/ethylene oxide-propylene oxide block copolymer nanoparticles as novel carriers for proteins and vaccines

scientific article published on 01 October 1997

Chitosan nanoparticles as a potential drug delivery system for the ocular surface: toxicity, uptake mechanism and in vivo tolerance.

scientific article published in April 2006

Chitosan nanoparticles as delivery systems for doxorubicin

scientific article published on 01 June 2001

Chitosan nanoparticles for drug delivery to the eye.

scientific article published on March 2009

Chitosan nanoparticles: a new vehicle for the improvement of the delivery of drugs to the ocular surface. Application to cyclosporin A.

scientific article published in August 2001

Chitosan-Alginate Blended Nanoparticles as Carriers for the Transmucosal Delivery of Macromolecules

scientific article published on 22 June 2009

Chitosan-Poly (I:C)-PADRE Based Nanoparticles as Delivery Vehicles for Synthetic Peptide Vaccines

scientific article

Chitosan-based drug nanocarriers: where do we stand?

scientific article published on 23 March 2012

Chitosan-based nanoparticles for improving immunization against hepatitis B infection.

scientific article published on 20 January 2010

Chitosan-based nanostructures: a delivery platform for ocular therapeutics.

scientific article published on December 2009

Chitosan-coated mesoporous MIL-100(Fe) nanoparticles as improved bio-compatible oral nanocarriers.

scientific article published on 3 March 2017

Chitosan/cyclodextrin nanoparticles as macromolecular drug delivery system

scientific article published on 12 March 2007

Chitosan/cyclodextrin nanoparticles can efficiently transfect the airway epithelium in vitro.

scientific article published on 14 October 2008

Chronic local tissue reactions, long-term immunogenicity and immunologic priming of mice and guinea pigs to tetanus toxoid encapsulated in biodegradable polymer microspheres composed of poly lactide-co-glycolide polymers.

scientific article

Co-delivery of RNAi and chemokine by polyarginine nanocapsules enables the modulation of myeloid-derived suppressor cells

scientific article published on 26 December 2018

Co-delivery of viral proteins and a TLR7 agonist from polysaccharide nanocapsules: a needle-free vaccination strategy.

scientific article published on 25 September 2013

Comparative in vitro evaluation of several colloidal systems, nanoparticles, nanocapsules, and nanoemulsions, as ocular drug carriers

scientific article published on 01 May 1996

Comparative uptake studies of bioadhesive and non-bioadhesive nanoparticles in human intestinal cell lines and rats: the effect of mucus on particle adsorption and transport.

scientific article

Current status of selected oral peptide technologies in advanced preclinical development and in clinical trials.

scientific article published on 24 February 2016

Design and characterisation of new nanoparticulate polymer blends for drug delivery

scientific article published on 01 January 2004

Design and characterization of a new drug nanocarrier made from solid-liquid lipid mixtures.

scientific article

Design and evaluation of chitosan/ethylcellulose mucoadhesive bilayered devices for buccal drug delivery

scientific article published on 01 November 1998

Design of microencapsulated chitosan microspheres for colonic drug delivery

scientific article published on 01 March 1998

Design of new formulations for topical ocular administration: polymeric nanocapsules containing metipranolol

scientific article published on 01 January 1993

Design of novel polysaccharidic nanostructures for gene delivery

scientific article published on January 29, 2008

Determinants of release rate of tetanus vaccine from polyester microspheres.

scientific article

Development and brain delivery of chitosan-PEG nanoparticles functionalized with the monoclonal antibody OX26.

scientific article

Development and characterization of CyA-loaded poly(lactic acid)–poly(ethylene glycol)PEG micro- and nanoparticles. Comparison with conventional PLA particulate carriers

article

Development and characterization of PLGA nanospheres and nanocapsules containing xanthone and 3-methoxyxanthone.

scientific article

Development and characterization of microencapsulated microspheres

scientific article published on 01 November 1994

Development of PLGA-mannosamine nanoparticles as oral protein carriers.

scientific article

Development of new chitosan-cellulose multicore microparticles for controlled drug delivery.

scientific article

Development of phosphorylated glucomannan-coated chitosan nanoparticles as nanocarriers for protein delivery.

scientific article

Docetaxel-loaded polyglutamic acid-PEG nanocapsules for the treatment of metastatic cancer

scientific article published on 29 July 2016

Effect of lysozyme on the stability of polyester nanocapsules and nanoparticles: stabilization approaches

scientific article published on 01 October 1997

Efficacy and mechanism of action of chitosan nanocapsules for oral peptide delivery

scientific article published on 16 March 2006

Efficacy of topical cyclosporine-loaded nanocapsules on keratoplasty rejection in the rat

scientific article published in January 1998

Enhanced in vivo therapeutic efficacy of plitidepsin-loaded nanocapsules decorated with a new poly-aminoacid-PEG derivative

scientific article published on 11 February 2015

Enhancing cutaneous delivery with laser technology: Almost there, but not yet

scientific article published on 16 October 2019

Exploring the efficiency of gallic acid-based dendrimers and their block copolymers with PEG as gene carriers.

scientific article

Formation of self-organized nanoparticles by lecithin/chitosan ionic interaction

scientific article published on 8 July 2006

Formulation of l-asparaginase-loaded poly(lactide-co-glycolide) nanoparticles: influence of polymer properties on enzyme loading, activity and in vitro release

scientific article published on March 2, 1998

Formulation strategies for the stabilization of tetanus toxoid in poly(lactide-co-glycolide) microspheres.

scientific article

Glucomannan, a promising polysaccharide for biopharmaceutical purposes.

scientific article published on 16 February 2008

Heparin-engineered mesoporous iron metal-organic framework nanoparticles: toward stealth drug nanocarriers

scientific article

Highly efficient system to deliver taxanes into tumor cells: docetaxel-loaded chitosan oligomer colloidal carriers.

scientific article

Highly versatile immunostimulating nanocapsules for specific immune potentiation.

scientific article published on 27 March 2014

Hyaluronan nanocapsules as a new vehicle for intracellular drug delivery.

scientific article published on 15 May 2013

Hyaluronic acid/chitosan-g-poly(ethylene glycol) nanoparticles for gene therapy: an application for pDNA and siRNA delivery

scientific article published on 21 September 2010

Improved delivery of angiogenesis inhibitors from PLGA:poloxamer blend micro- and nanoparticles.

scientific article

Improved immunogenicity of a core-coated tetanus toxoid delivery system

scientific article published on 01 November 1999

Improvement of ocular penetration of amikacin sulphate by association to poly(butylcyanoacrylate) nanoparticles

scientific article published on 01 August 1991

In vivo evaluation of poly-l-asparagine nanocapsules as carriers for anti-cancer drug delivery.

scientific article published on 17 October 2013

Insulin-loaded PLGA nanoparticles for oral administration: an in vitro physico-chemical characterization

scientific article published on 01 February 2009

Intracellular delivery of docetaxel using freeze-dried polysaccharide nanocapsules.

scientific article

Ionically crosslinked chitosan/tripolyphosphate nanoparticles for oligonucleotide and plasmid DNA delivery.

scientific article

Joint effects of monomer and stabilizer concentrations on physico-chemical characteristics of poly(butyl 2-cyanoacrylate) nanoparticles

scientific article published on 01 October 1990

Lipid-based nanocarriers for oral peptide delivery.

scientific article published on 11 April 2016

Low molecular weight chitosan nanoparticles as new carriers for nasal vaccine delivery in mice

scientific article published in January 2004

Lymphatic Targeting of Nanosystems for Anticancer Drug Therapy.

scientific article published on 16 December 2015

Mauritian cynomolgus macaques with M3M4 MHC genotype control SIVmac251 infection.

scientific article

Modulating the immune system through nanotechnology.

scientific article published on 9 October 2017

Mucosal delivery of liposome-chitosan nanoparticle complexes.

scientific article

Nanoengineering of vaccines using natural polysaccharides.

scientific article published on 03 June 2015

Nanomedicine and cancer immunotherapy - targeting immunosuppressive cells

scientific article published on August 2015

Nanomedicines for overcoming biological barriers.

scientific article published on April 2004

Nanoparticles as carriers for nasal vaccine delivery.

scientific article

Nanoparticles as protein and gene carriers to mucosal surfaces.

scientific article published on December 2008

Nanoparticles based on PLGA:poloxamer blends for the delivery of proangiogenic growth factors

scientific article published on 12 August 2010

Nanoparticles for nasal vaccination.

scientific article published on 13 December 2008

Nanotherapies for the treatment of ocular diseases.

scientific article published on 26 February 2015

Natural and cross-inducible anti-SIV antibodies in Mauritian cynomolgus macaques

scientific article published on 5 October 2017

New generation of hybrid poly/oligosaccharide nanoparticles as carriers for the nasal delivery of macromolecules.

scientific article

New strategies for the microencapsulation of tetanus vaccine.

scientific article published on May 1998

New surface-modified lipid nanoparticles as delivery vehicles for salmon calcitonin.

scientific article published on 7 April 2005

Nose-to-brain peptide delivery - The potential of nanotechnology

scientific article published on 4 November 2017

Novel drug nanocarriers combining hydrophilic cyclodextrins and chitosan

scientific article published on 01 April 2008

Novel hyaluronan-based nanocarriers for transmucosal delivery of macromolecules.

scientific article published in May 2008

Novel hyaluronic acid-chitosan nanoparticles for ocular gene therapy.

scientific article

Ocular tolerance to a topical formulation of hyaluronic acid and chitosan-based nanoparticles.

scientific article published in May 2010

Oral Delivery of Biologics for Precision Medicine

scientific article published on 20 June 2019

Oral delivery of peptides: opportunities and issues for translation.

scientific article

PEG-PLA nanoparticles as carriers for nasal vaccine delivery

scientific article published on 01 January 2004

PEGylated lipid nanocapsules with improved drug encapsulation and controlled release properties

scientific article published in January 2014

PLA-PEG particles as nasal protein carriers: the influence of the particle size.

scientific article published on 18 January 2005

PLGA:poloxamer and PLGA:poloxamine blend nanoparticles: new carriers for gene delivery.

scientific article

PLGA:poloxamer blend micro- and nanoparticles as controlled release systems for synthetic proangiogenic factors.

scientific article published on 30 September 2010

Pharmacokinetic, pharmacodynamic and biodistribution following oral administration of nanocarriers containing peptide and protein drugs.

scientific article published on 16 June 2016

Physical Properties and Stability of Soft Gelled Chitosan-Based Nanoparticles

scientific article published on 27 October 2016

Poly-L-asparagine nanocapsules as anticancer drug delivery vehicles.

scientific article published on 13 August 2013

Polyaminoacid nanocapsules for drug delivery to the lymphatic system: Effect of the particle size

scientific article published on 19 May 2016

Polyarginine Nanocapsules as a Potential Oral Peptide Delivery Carrier

scientific article published on 14 November 2016

Polyarginine nanocapsules: A versatile nanocarrier with potential in transmucosal drug delivery.

scientific article

Polyester nanocapsules as new topical ocular delivery systems for cyclosporin A

scientific article published in 1996

Polyglutamic acid-PEG nanocapsules as long circulating carriers for the delivery of docetaxel.

scientific article

Polymer-based Oral Peptide Nanomedicines

scientific article published on May 1, 2012

Polymeric nanocapsules: a potential new therapy for corneal wound healing.

scientific article published on 8 July 2016

Polysaccharide Nanoparticles Can Efficiently Modulate the Immune Response against an HIV Peptide Antigen

scientific article published on 23 April 2019

Preparation and in vitro evaluation of chitosan nanoparticles containing a caspase inhibitor

scientific article published in July 2005

Preparation of Poly(Lactic Acid) (PLA) and Poly(Ethylene Oxide) (PEO) Nanoparticles as Carriers for Gene Delivery

article

Protection of the peptide glutathione by complex formation with alpha-cyclodextrin: NMR spectroscopic analysis and stability study

scientific article published on 02 June 2006

Protein encapsulation and release from poly(lactide-co-glycolide) microspheres: effect of the protein and polymer properties and of the co-encapsulation of surfactants.

scientific article published in May 1998

Protein encapsulation within polyethylene glycol-coated nanospheres. I. Physicochemical characterization.

scientific article published on October 1998

Rational design of polyarginine nanocapsules intended to help peptides overcoming intestinal barriers

scientific article published on 21 February 2017

Reacetylated chitosan microspheres for controlled delivery of anti-microbial agents to the gastric mucosa.

scientific article

Recent advances in vaccine delivery.

scientific article published on 15 December 2015

Reduction of cardiovascular side effects associated with ocular administration of metipranolol by inclusion in polymeric nanocapsules

scientific article published on 01 January 1992

Selective interaction of PEGylated polyglutamic acid nanocapsules with cancer cells in a 3D model of a metastatic lymph node

scientific article published on 23 June 2016

Stealth PLA-PEG nanoparticles as protein carriers for nasal administration

scientific article published on 01 February 1998

Surface-modified PLGA-based nanoparticles that can efficiently associate and deliver virus-like particles.

scientific article published in August 2010

Synthetic nanocarriers for the delivery of polynucleotides to the eye.

scientific article published on 2 March 2017

Systemic heparin delivery by the pulmonary route using chitosan and glycol chitosan nanoparticles.

scientific article published on 20 February 2013

Targeting cancer with hyaluronic acid-based nanocarriers: recent advances and translational perspectives

scientific article published on 16 August 2016

Targeting tumor associated macrophages: The new challenge for nanomedicine

scientific article published on 20 September 2017

The effect of a PEG versus a chitosan coating on the interaction of drug colloidal carriers with the ocular mucosa.

scientific article

The interaction of protamine nanocapsules with the intestinal epithelium: A mechanistic approach

scientific article published on 6 October 2016

The performance of nanocarriers for transmucosal drug delivery.

scientific article published on July 2006

The potential of chitosan for the oral administration of peptides.

scientific article

The potential of chitosan in ocular drug delivery.

scientific article published on November 2003

The role of cyclooxygenase (COX)-2 derived prostanoids on vasoconstrictor responses to phenylephrine is increased by exposure to low mercury concentration.

scientific article published in February 2010

The size and composition of polymeric nanocapsules dictate their interaction with macrophages and biodistribution in zebrafish

scientific article published on 12 July 2019

Transport of PLA-PEG particles across the nasal mucosa: effect of particle size and PEG coating density.

scientific article

Vaccine delivery carriers: insights and future perspectives.

scientific article published on 23 April 2012

[Oral bioavailability of cefadroxil: influence of food]

scientific article published on 01 December 1982

[Polymeric nanoparticles: new systems for improving ocular bioavailability of drugs]

scientific article published on 01 August 2001