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List of works by Norbert Weissmann

5-HT2B receptor antagonists inhibit fibrosis and protect from RV heart failure

scientific article

A RASSF1A-HIF1α loop drives Warburg effect in cancer and pulmonary hypertension

scientific article published on 13 May 2019

ASK1 Inhibition Halts Disease Progression in Preclinical Models of Pulmonary Arterial Hypertension

scientific article published on 14 September 2017

Activation of TRPC6 channels is essential for lung ischaemia-reperfusion induced oedema in mice.

scientific article published on 31 January 2012

Activation of soluble guanylate cyclase reverses experimental pulmonary hypertension and vascular remodeling

scientific article published on 3 January 2006

Acute O2 sensing through HIF2α-dependent expression of atypical cytochrome oxidase subunits in arterial chemoreceptors

scientific article published on 21 January 2020

Adenylate Kinase 4—A Key Regulator of Proliferation and Metabolic Shift in Human Pulmonary Arterial Smooth Muscle Cells via Akt and HIF-1α Signaling Pathways

scientific article published on 26 September 2021

Altered proteasome function in right ventricular hypertrophy

scientific article published on 01 February 2020

Alveolar epithelial barrier functions in ventilated perfused rabbit lungs

scientific article published in May 2001

Amphiphilic, low molecular weight poly(ethylene imine) derivatives with enhanced stability for efficient pulmonary gene delivery

scientific article published on February 2011

Amplification of the pulmonary vasodilatory response to inhaled iloprost by subthreshold phosphodiesterase types 3 and 4 inhibition in severe pulmonary hypertension

scientific article published in November 2002

Amplified canonical transforming growth factor-β signalling via heat shock protein 90 in pulmonary fibrosis

scientific article published on 19 December 2016

An excess dietary vitamin E concentration does not influence Nrf2 signaling in the liver of rats fed either soybean oil or salmon oil.

scientific article

Angiotensin-converting enzyme 2 activation for treatment of pulmonary hypertension

scientific article published on 01 March 2013

Anti-human neutrophil antigen-3a induced transfusion-related acute lung injury in mice by direct disturbance of lung endothelial cells

scientific article published on 5 September 2013

Antibody-induced neutrophil activation as a trigger for transfusion-related acute lung injury in an ex vivo rat lung model

scientific article

Antioxidant vitamin C improves endothelial function in obstructive sleep apnea

scientific article published on 26 January 2006

Antiremodeling effects of iloprost and the dual-selective phosphodiesterase 3/4 inhibitor tolafentrine in chronic experimental pulmonary hypertension

scientific article published on 18 March 2004

Apical, but not basolateral, endotoxin preincubation protects alveolar epithelial cells against hydrogen peroxide-induced loss of barrier function: the role of nitric oxide synthesis

scientific article

Arterial hypertension in a murine model of sleep apnea: role of NADPH oxidase 2.

scientific article published on February 2014

Atrial natriuretic peptide in severe primary and nonprimary pulmonary hypertension: response to iloprost inhalation.

scientific article

Author Correction: NADPH oxidase subunit NOXO1 is a target for emphysema treatment in COPD

scientific article published on 01 July 2020

BDNF/TrkB signaling augments smooth muscle cell proliferation in pulmonary hypertension

scientific article published on 8 October 2012

Basic features of hypoxic pulmonary vasoconstriction in mice

scientific article (publication date: 15 January 2004)

Bypassing mitochondrial complex III using alternative oxidase inhibits acute pulmonary oxygen sensing

scientific article published on 15 April 2020

COPD-associated pulmonary hypertension: clinical implications and current methods for treatment

scientific article published on 21 May 2016

CRISPR/Cas9-mediated knockout of p22phox leads to loss of Nox1 and Nox4, but not Nox5 activity

scientific article published on 24 August 2016

Cellular and molecular basis of pulmonary arterial hypertension

scientific article published on June 2009

Cellular and molecular mechanisms of hypoxia-inducible factor driven vascular remodeling

scientific article published on 01 May 2007

Changes in pulmonary surfactant function and composition in bleomycin-induced pneumonitis and fibrosis

scientific article published in March 2004

Characterization of a murine model of monocrotaline pyrrole-induced acute lung injury.

scientific article

Chronic intratracheal application of the soluble guanylyl cyclase stimulator BAY 41-8543 ameliorates experimental pulmonary hypertension

scientific article published on 31 March 2017

Chronic sildenafil treatment inhibits monocrotaline-induced pulmonary hypertension in rats

scientific article published on 4 September 2003

Chymase: a multifunctional player in pulmonary hypertension associated with lung fibrosis

scientific article published on 25 June 2015

Cigarette Smoke-Induced Emphysema and Pulmonary Hypertension Can Be Prevented by Phosphodiesterase 4 and 5 Inhibition in Mice

scientific article published on 9 June 2015

Cigarette smoke causes acute airway disease and exacerbates chronic obstructive lung disease in neonatal mice.

scientific article published on 22 July 2016

Circulating adrenomedullin in obstructive sleep apnoea

scientific article

Classical transient receptor potential channel 1 in hypoxia-induced pulmonary hypertension.

scientific article

Classical transient receptor potential channel 6 (TRPC6) is essential for hypoxic pulmonary vasoconstriction and alveolar gas exchange

scholarly article

Coaerosolization of phosphodiesterase inhibitors markedly enhances the pulmonary vasodilatory response to inhaled iloprost in experimental pulmonary hypertension. Maintenance of lung selectivity

scientific article published on November 2001

Cofilin, a hypoxia-regulated protein in murine lungs identified by 2DE: role of the cytoskeletal protein cofilin in pulmonary hypertension

scientific article

Combination of nonspecific PDE inhibitors with inhaled prostacyclin in experimental pulmonary hypertension

scientific article published in December 2001

Combination therapy with oral sildenafil and inhaled iloprost for severe pulmonary hypertension.

scientific article

Combined tyrosine and serine/threonine kinase inhibition by sorafenib prevents progression of experimental pulmonary hypertension and myocardial remodeling

scientific article published on 27 October 2008

Comparison of pharmacokinetics and vasodilatory effect of nebulized and infused iloprost in experimental pulmonary hypertension: rapid tolerance development

scientific article published in January 2006

Conebulization of surfactant and urokinase restores gas exchange in perfused lungs with alveolar fibrin formation

scientific article published on 01 April 2001

Congenital erythropoietin over-expression causes "anti-pulmonary hypertensive" structural and functional changes in mice, both in normoxia and hypoxia

scientific article (publication date: September 2005)

Correction: Improvement of right heart structure and function by BAY41-8543 in pulmonary artery banded mice.

scientific article published on 14 September 2011

Cytochrome P450 enzymes but not NADPH oxidases are the source of the NADPH-dependent lucigenin chemiluminescence in membrane assays

scientific article published on 15 November 2016

Cytochrome P450 epoxygenase-derived 5,6-epoxyeicosatrienoic acid relaxes pulmonary arteries in normoxia but promotes sustained pulmonary vasoconstriction in hypoxia

scientific article published on 07 June 2020

Cytochrome c oxidase subunit 4 isoform 2-knockout mice show reduced enzyme activity, airway hyporeactivity, and lung pathology

scientific article

Detection of reactive oxygen species in isolated, perfused lungs by electron spin resonance spectroscopy

scientific article

Development of a Gas-Tight Microfluidic System for Raman Sensing of Single Pulmonary Arterial Smooth Muscle Cells Under Normoxic/Hypoxic Conditions

scientific article published on 26 September 2018

Diacylglycerol regulates acute hypoxic pulmonary vasoconstriction via TRPC6.

scientific article published on 4 February 2011

Differences in hemodynamic and oxygenation responses to three different phosphodiesterase-5 inhibitors in patients with pulmonary arterial hypertension: a randomized prospective study

scientific article published in October 2004

Differential Alterations of the Mitochondrial Morphology and Respiratory Chain Complexes during Postnatal Development of the Mouse Lung.

scientific article published on 19 December 2017

Differential Impact of Ultrasonically Nebulized Versus Tracheal-instilled Surfactant on Ventilation-Perfusion (V˙A/Q˙) Mismatch in a Model of Acute Lung Injury

scientific article published on 01 January 2000

Direct and simultaneous profiling of epoxyeicosatrienoic acid enantiomers by capillary tandem column chiral-phase liquid chromatography with dual online photodiode array and tandem mass spectrometric detection

scientific article

Direct eicosanoid profiling of the hypoxic lung by comprehensive analysis via capillary liquid chromatography with dual online photodiode-array and tandem mass-spectrometric detection

scientific article

Discovery and pharmacological characterization of a novel potent inhibitor of diacylglycerol-sensitive TRPC cation channels

scientific article published on 19 May 2015

Disruption of the Hepcidin/Ferroportin Regulatory System Causes Pulmonary Iron Overload and Restrictive Lung Disease

scientific article

Downregulation of hypoxic vasoconstriction by chronic hypoxia in rabbits: effects of nitric oxide

scientific article published on 14 November 2002

Dysregulation of the IL-13 receptor system: a novel pathomechanism in pulmonary arterial hypertension.

scientific article

Effect of Riociguat and Sildenafil on Right Heart Remodeling and Function in Pressure Overload Induced Model of Pulmonary Arterial Banding.

scientific article published on 3 January 2018

Effect of nitric oxide synthase (NOS) inhibition on macro- and microcirculation in a model of rat endotoxic shock

scientific article published on 01 April 2006

Effects of Multikinase inhibitors on pressure overload-induced right ventricular remodelling

scientific article published on 14 August 2013

Effects of NADPH oxidase inhibitors on hypoxic vasoconstriction in buffer-perfused rabbit lungs

scientific article published on 01 May 1995

Effects of arachidonic acid metabolism on hypoxic vasoconstriction in rabbit lungs

scientific article published on 01 September 1998

Effects of carbon monoxide-releasing molecules on pulmonary vasoreactivity in isolated perfused lungs

scientific article

Effects of dimethylarginine dimethylaminohydrolase-1 overexpression on the response of the pulmonary vasculature to hypoxia.

scientific article published on September 2013

Effects of hypercapnia and NO synthase inhibition in sustained hypoxic pulmonary vasoconstriction.

scientific article published on 31 January 2012

Effects of hypercapnia with and without acidosis on hypoxic pulmonary vasoconstriction.

scientific article published on 28 August 2009

Effects of mitochondrial inhibitors and uncouplers on hypoxic vasoconstriction in rabbit lungs

scientific article

Effects of multikinase inhibitors on pressure overload-induced right ventricular remodeling.

scientific article

Effects of phosphodiesterase 4 inhibition on bleomycin-induced pulmonary fibrosis in mice

scientific article

Effects of riociguat in severe experimental pulmonary hypertension.

scientific article published in August 2011

Endothelin-1 driven proliferation of pulmonary arterial smooth muscle cells is c-fos dependent.

scientific article published on 10 July 2014

Endothelin-1 inhibits background two-pore domain channel TASK-1 in primary human pulmonary artery smooth muscle cells

scientific article published on 2 February 2009

Endurance and Resistance Training Affect High Fat Diet-Induced Increase of Ceramides, Inflammasome Expression, and Systemic Inflammation in Mice

scientific article

Enhanced gene expression and reduced toxicity in mice using polyplexes of low-molecular-weight poly(ethylene imine) for pulmonary gene delivery

scientific article

Eplerenone attenuates pathological pulmonary vascular rather than right ventricular remodeling in pulmonary arterial hypertension.

scientific article published on 2 March 2018

Epoxyeicosatrienoates are the dominant eicosanoids in human lungs upon microbial challenge

scientific article published on 8 April 2010

Epoxyeicosatrienoic acids and the soluble epoxide hydrolase are determinants of pulmonary artery pressure and the acute hypoxic pulmonary vasoconstrictor response

scientific article

Essential role of complex II of the respiratory chain in hypoxia-induced ROS generation in the pulmonary vasculature.

scientific article published on 10 January 2003

Estimate of oxygen consumption and intracellular zinc concentration of human spermatozoa in relation to motility.

scientific article published in March 2003

Evaluating Systolic and Diastolic Cardiac Function in Rodents Using Microscopic Computed Tomography

scientific article published on 01 December 2018

Evidence for a role of protein kinase C in hypoxic pulmonary vasoconstriction

article

Evidence for the Fucoidan/P-Selectin Axis as a Therapeutic Target in Hypoxia-induced Pulmonary Hypertension

scientific article published on 01 June 2019

Exercise Affects T-Cell Function by Modifying Intracellular Calcium Homeostasis

scientific article

Exercise training reverses inflammation and muscle wasting after tobacco smoke exposure.

scientific article published in November 2017

Expression and activity of phosphodiesterase isoforms during epithelial mesenchymal transition: the role of phosphodiesterase 4.

scientific article published on 16 September 2009

Expression and function of soluble guanylate cyclase in pulmonary arterial hypertension.

scientific article

Expression profiling of laser-microdissected intrapulmonary arteries in hypoxia-induced pulmonary hypertension

scientific article

FGF10 Triggers <i>De Novo</i> Alveologenesis in a Bronchopulmonary Dysplasia Model: Impact on Resident Mesenchymal Niche Cells

scientific article published in 2022

Fhl-1, a new key protein in pulmonary hypertension.

scientific article

First acute haemodynamic study of soluble guanylate cyclase stimulator riociguat in pulmonary hypertension

scientific article

Function of NADPH oxidase 1 in pulmonary arterial smooth muscle cells after monocrotaline-induced pulmonary vascular remodeling

scientific article published on 20 July 2013

Functional and muscular adaptations in an experimental model for isometric strength training in mice

scientific article

Glycogen synthase kinase 3beta contributes to proliferation of arterial smooth muscle cells in pulmonary hypertension.

scientific article

Heme oxygenase-2 and large-conductance Ca2+-activated K+ channels: lung vascular effects of hypoxia.

scientific article

Hepatocyte growth factor induces a proangiogenic phenotype and mobilizes endothelial progenitor cells by activating Nox2.

scientific article

Histological characterization of mast cell chymase in patients with pulmonary hypertension and chronic obstructive pulmonary disease.

scientific article

Hydrogen Peroxide-Induced Increase in Lung Endothelial and Epithelial Permeability-Effect of Adenylate Cyclase Stimulation and Phosphodiesterase Inhibition

scientific article published on 01 July 1995

Hypoxia enhances platelet-derived growth factor signaling in the pulmonary vasculature by down-regulation of protein tyrosine phosphatases.

scientific article

Hypoxia in lung vascular biology and disease

scientific article published on 11 July 2006

Hypoxia induces Kv channel current inhibition by increased NADPH oxidase-derived reactive oxygen species

scientific article published on 16 December 2011

Hypoxia- and non-hypoxia-related pulmonary hypertension - established and new therapies.

scientific article published on August 2006

Hypoxia- or PDGF-BB-dependent paxillin tyrosine phosphorylation in pulmonary hypertension is reversed by HIF-1α depletion or imatinib treatment.

scientific article published on 18 September 2014

Hypoxia-dependent reactive oxygen species signaling in the pulmonary circulation: focus on ion channels

scientific article published on February 2015

Hypoxia-dependent regulation of nonphagocytic NADPH oxidase subunit NOX4 in the pulmonary vasculature

scientific article

Hypoxia-driven mechanisms in lung biology and disease: a new review series of the ERS Lung Science Conference

scientific article published on 01 April 2008

Hypoxia-induced pulmonary hypertension: Different impact of iloprost, sildenafil, and nitric oxide

scientific article published on 20 July 2007

Hypoxia-induced pulmonary hypertension: comparison of soluble epoxide hydrolase deletion vs. inhibition.

scientific article

Hypoxic pulmonary artery fibroblasts trigger proliferation of vascular smooth muscle cells: role of hypoxia-inducible transcription factors

scientific article published on 21 August 2002

Hypoxic pulmonary hypertension in mice with constitutively active platelet-derived growth factor receptor-β.

scientific article

Hypoxic pulmonary vasoconstriction in isolated mouse pulmonary arterial vessels

scientific article published on 06 July 2018

Hypoxic pulmonary vasoconstriction--triggered by an increase in reactive oxygen species?

scientific article published on 01 January 2006

Hypoxic pulmonary vasoconstriction: a multifactorial response?

Hypoxic vasoconstriction in buffer-perfused rabbit lungs

scientific article published on 01 May 1995

Hypoxic vasoconstriction in intact lungs: a role for NADPH oxidase-derived H(2)O(2)?

Identification of novel Nox4 splice variants with impact on ROS levels in A549 cells.

scientific article published on April 2005

Identification of proteins in laser-microdissected small cell numbers by SELDI-TOF and Tandem MS

scientific article

Identification of right heart-enriched genes in a murine model of chronic outflow tract obstruction

article

Iloprost-induced desensitization of the prostacyclin receptor in isolated rabbit lungs

scientific article (publication date: 26 January 2007)

Immune and inflammatory cell involvement in the pathology of idiopathic pulmonary arterial hypertension

scientific article published on 6 September 2012

Immunomodulation by n-3- versus n-6-rich lipid emulsions in murine acute lung injury—Role of platelet-activating factor receptor

scientific article published on 01 February 2007

Impact of HIF-1alpha and HIF-2alpha on proliferation and migration of human pulmonary artery fibroblasts in hypoxia

scientific article published on November 2005

Impact of S-adenosylmethionine decarboxylase 1 on pulmonary vascular remodeling

scientific article published on 27 January 2014

Impact of mitochondria and NADPH oxidases on acute and sustained hypoxic pulmonary vasoconstriction

scientific article published on 15 December 2005

Impact of short- and medium-chain fatty acids on mitochondrial function in severe inflammation

scientific article

Impact of the mitochondria-targeted antioxidant MitoQ on hypoxia-induced pulmonary hypertension

scientific article

Improvement of right heart structure and function by BAY 41-8543 in pulmonary artery banded mice.

scientific article published in August 2011

In vivo TRPC functions in the cardiopulmonary vasculature.

scientific article published on 11 April 2007

Inactivation of sestrin 2 induces TGF-beta signaling and partially rescues pulmonary emphysema in a mouse model of COPD.

scientific article published on 27 January 2010

Increased S100A4 expression in the vasculature of human COPD lungs and murine model of smoke-induced emphysema

scientific article published on 20 October 2015

Increased levels and reduced catabolism of asymmetric and symmetric dimethylarginines in pulmonary hypertension

scientific article published on 12 April 2005

Increased neutrophil mediator release in patients with pulmonary hypertension--suppression by inhaled iloprost

scientific article published in December 2003

Increased protein arginine methylation in chronic hypoxia: role of protein arginine methyltransferases

scientific journal article

Inducible NOS Inhibition Reverses Tobacco-Smoke-Induced Emphysema and Pulmonary Hypertension in Mice

scientific article published on 01 October 2011

Inflammation, immunological reaction and role of infection in pulmonary hypertension.

scientific article published on January 2011

Inhaled iloprost is a potent acute pulmonary vasodilator in HIV-related severe pulmonary hypertension.

scientific article published on February 2004

Inhaled iloprost reverses vascular remodeling in chronic experimental pulmonary hypertension

scientific article published on 5 May 2005

Inhaled tolafentrine reverses pulmonary vascular remodeling via inhibition of smooth muscle cell migration

scientific article

Inhibition of microRNA-17 improves lung and heart function in experimental pulmonary hypertension

scientific article published on 8 December 2011

Inhibition of phosphodiesterase 4 enhances lung alveolarisation in neonatal mice exposed to hyperoxia.

scientific article

Interactions of peroxynitrite with uric acid in the presence of ascorbate and thiols: implications for uncoupling endothelial nitric oxide synthase.

scientific article published in August 2005

Interactions of peroxynitrite, tetrahydrobiopterin, ascorbic acid, and thiols: implications for uncoupling endothelial nitric-oxide synthase.

scientific article

Intermedin/adrenomedullin-2 is a hypoxia-induced endothelial peptide that stabilizes pulmonary microvascular permeability.

scientific article published on 14 August 2009

Involvement of mast cells in monocrotaline-induced pulmonary hypertension in rats

scientific article

Is PKM2 Phosphorylation a Prerequisite for Oligomer Disassembly in Pulmonary Arterial Hypertension?

scientific article published on 01 December 2019

Knock out of the NADPH oxidase Nox4 has no impact on life span in mice

scientific article published on 22 December 2016

Long Noncoding RNA MANTIS Facilitates Endothelial Angiogenic Function

scientific article published on 28 March 2017

Long-term treatment with sildenafil in chronic thromboembolic pulmonary hypertension

scientific article published on 09 August 2007

Low density lipoprotein receptor-related protein 1 couples β1 integrin activation to degradation

scientific article published on 7 November 2017

Low-dose Systemic Phosphodiesterase Inhibitors Amplify the Pulmonary Vasodilatory Response to Inhaled Prostacyclin in Experimental Pulmonary Hypertension

scientific article published on 01 November 1999

Ltbp4 regulates Pdgfrβ expression via TGFβ-dependent modulation of Nrf2 transcription factor function.

scientific article

Lung Ischaemia-Reperfusion Injury: The Role of Reactive Oxygen Species

scientific article published in January 2017

Lung cGMP release subsequent to NO inhalation in pulmonary hypertension: responders versus nonresponders

scientific article

Lung developmental arrest caused by PDGF-A deletion: consequences for the adult mouse lung

scientific article published on 18 March 2020

Lung vasodilatory response to inhaled iloprost in experimental pulmonary hypertension: amplification by different type phosphodiesterase inhibitors

scientific article

Lysyl oxidases play a causal role in vascular remodeling in clinical and experimental pulmonary arterial hypertension

scientific article

Maintained right ventricular pressure overload induces ventricular-arterial decoupling in mice

scientific article published on 19 December 2016

Mast cell chymase: an indispensable instrument in the pathological symphony of idiopathic pulmonary fibrosis?

scientific article published on 25 February 2013

Measurement of exhaled hydrogen peroxide from rabbit lungs

scientific article

Mechanical ventilation drives pneumococcal pneumonia into lung injury and sepsis in mice: protection by adrenomedullin

scientific article

Mechanism of transfusion-related acute lung injury induced by HLA class II antibodies

scientific article published on 28 October 2010

Mitochondrial Complex IV Subunit 4 Isoform 2 Is Essential for Acute Pulmonary Oxygen Sensing

scientific article published on 15 June 2017

Mitochondrial complex II is essential for hypoxia-induced pulmonary vasoconstriction of intra- but not of pre-acinar arteries.

scientific article

Mitochondrial complex II participates in normoxic and hypoxic regulation of α-keto acids in the murine heart.

scientific article published on October 2010

Mitochondrial cytochrome redox states and respiration in acute pulmonary oxygen sensing

scientific article published on 01 June 2010

Mitochondrial hyperpolarization in pulmonary vascular remodeling. Mitochondrial uncoupling protein deficiency as disease model

scientific article published in September 2013

Molecular mechanisms of hypoxia-inducible factor-induced pulmonary arterial smooth muscle cell alterations in pulmonary hypertension

scientific article published on 30 July 2015

Monocytes recruited into the alveolar air space of mice show a monocytic phenotype but upregulate CD14

NADPH oxidase 4 is not involved in hypoxia-induced pulmonary hypertension.

scientific article

NADPH oxidase 4 limits bone mass by promoting osteoclastogenesis

scientific article

NADPH oxidase subunit NOXO1 is a target for emphysema treatment in COPD

scientific article published on 08 June 2020

NADPH oxidases in cardiovascular disease.

scientific article published on 02 May 2010

NADPH oxidases-do they play a role in TRPC regulation under hypoxia?

scientific article published on October 2015

NO and reactive oxygen species are involved in biphasic hypoxic vasoconstriction of isolated rabbit lungs.

scientific article

NOX4 regulates ROS levels under normoxic and hypoxic conditions, triggers proliferation, and inhibits apoptosis in pulmonary artery adventitial fibroblasts

scientific article published in October 2008

NPY/Y₁ receptor-mediated vasoconstrictory and proliferative effects in pulmonary hypertension

scientific article

Nebulization of the acidified sodium nitrite formulation attenuates acute hypoxic pulmonary vasoconstriction

scientific article published on 21 June 2010

Nestin-expressing vascular wall cells drive development of pulmonary hypertension.

scientific article published on 23 December 2015

Neurotrophic tyrosine kinase receptor B/neurotrophin 4 signaling axis is perturbed in clinical and experimental pulmonary fibrosis.

scientific article

Nitric oxide (NO)-dependent but not NO-independent guanylate cyclase activation attenuates hypoxic vasoconstriction in rabbit lungs

scientific article published in August 2000

Nitric oxide generation and hypoxic vasoconstriction in buffer-perfused rabbit lungs

scientific article published on 01 April 1995

Nitric-oxide-mediated zinc release: a new (modulatory) pathway in hypoxic pulmonary vasoconstriction

scientific article published on 01 June 2008

Nitro blue tetrazolium inhibits but does not mimic hypoxic vasoconstriction in isolated rabbit lungs.

scientific article published in May 1998

Notch1 signalling regulates endothelial proliferation and apoptosis in pulmonary arterial hypertension.

scientific article

Novel and emerging therapies for pulmonary hypertension

scientific article published on February 2014

Novel soluble guanylyl cyclase stimulator BAY 41-2272 attenuates ischemia-reperfusion-induced lung injury

scientific article

Nox family NADPH oxidases in mechano-transduction: mechanisms and consequences

scientific article

Nox family NADPH oxidases: Molecular mechanisms of activation

scientific article

Nox4 is a protective reactive oxygen species generating vascular NADPH oxidase

scientific article

Obstructive sleep apnea in a patient with the Melkersson-Rosenthal syndrome

scientific article published on 28 October 2009

Obstructive sleep apnea, oxidative stress and cardiovascular disease: lessons from animal studies

scientific article published on 03 March 2013

On-line measurement of nitric oxide generation in buffer-perfused rabbit lungs

scientific article published on 01 April 1995

Oral sildenafil as long-term adjunct therapy to inhaled iloprost in severe pulmonary arterial hypertension

scientific article published on July 2003

Organizers and activators: Cytosolic Nox proteins impacting on vascular function.

scientific article published on 20 March 2017

Oxidative injury of the pulmonary circulation in the perinatal period: Short- and long-term consequences for the human cardiopulmonary system

scientific article

Oxygen sensing and signal transduction in hypoxic pulmonary vasoconstriction.

scientific article

Oxygen sensors in hypoxic pulmonary vasoconstriction

scientific article published on September 2006

Oxygen-dependent expression of cytochrome c oxidase subunit 4-2 gene expression is mediated by transcription factors RBPJ, CXXC5 and CHCHD2

scientific article

PAR-2 inhibition reverses experimental pulmonary hypertension.

scientific article

Partial reversal of experimental pulmonary hypertension by phosphodiesterase-3/4 inhibition.

scientific article published on 21 November 2007

Pathobiology, pathology and genetics of pulmonary hypertension: Recommendations of the Cologne Consensus Conference 2016

scientific article published on 19 October 2016

Pathophysiology and treatment of high-altitude pulmonary vascular disease.

scientific article

Paxillin regulates pulmonary arterial smooth muscle cell function in pulmonary hypertension

scientific article

Peroxisome proliferator-activated receptor-alpha reduces inflammation and vascular leakage in a murine model of acute lung injury

scientific article published on 24 July 2008

Pharmacokinetics and metabolism of infused versus inhaled iloprost in isolated rabbit lungs

scientific article published in November 2002

Phosphodiesterase 1 upregulation in pulmonary arterial hypertension: target for reverse-remodeling therapy

scientific article

Phosphodiesterase 10A upregulation contributes to pulmonary vascular remodeling

scientific article

Phosphodiesterase 6 subunits are expressed and altered in idiopathic pulmonary fibrosis.

scientific article

Physiologic basis for the treatment of pulmonary hypertension.

scientific article

Plasma MMP2/TIMP4 Ratio at Follow-up Assessment Predicts Disease Progression of Idiopathic Pulmonary Arterial Hypertension.

scientific article published on 17 May 2017

Post-stroke inhibition of induced NADPH oxidase type 4 prevents oxidative stress and neurodegeneration

scientific article

Postnatal development of the bronchiolar club cells of distal airways in the mouse lung: stereological and molecular biological studies

scientific article published on 21 January 2016

Pressure Overload Creates Right Ventricular Diastolic Dysfunction in a Mouse Model: Assessment by Echocardiography

scientific article published in April 2015

Pressure overload leads to an increased accumulation and activity of mast cells in the right ventricle

scientific article

Prevention of bleomycin-induced lung fibrosis by aerosolization of heparin or urokinase in rabbits

scientific article

Pro-proliferative and inflammatory signaling converge on FoxO1 transcription factor in pulmonary hypertension

scientific article published on 26 October 2014

Prolonged vasodilatory response to nanoencapsulated sildenafil in pulmonary hypertension

scientific article published on 19 September 2015

Prostanoids and phosphodiesterase inhibitors in experimental pulmonary hypertension

scientific article

Pulmonale Hypertonie und schlafbezogene Atmungsstörungen

scientific article published on 01 April 2005

Pulmonary arterial hypertension--a disease of the immune system?

scientific article published on 9 December 2014

Reactive Oxygen Species Differentially Modulate the Metabolic and Transcriptomic Response of Endothelial Cells

scientific article published in 2022

Recent advances in oxygen sensing and signal transduction in hypoxic pulmonary vasoconstriction

scientific article published on 27 July 2017

Redox signaling and reactive oxygen species in hypoxic pulmonary vasoconstriction

scientific article published on 27 August 2010

Redox-mediated signal transduction by cardiovascular Nox NADPH oxidases.

scientific article published on 19 February 2014

Regeneration von Lungenparenchym - eine Chance für die Zukunft

scientific article published on 01 April 2006

Regulation of hypoxic pulmonary vasoconstriction: basic mechanisms.

scientific article

Reply to Bogaard et al.: Emphysema Is-at the Most-Only a Mild Phenotype in the Sugen/Hypoxia Rat Model of Pulmonary Arterial Hypertension

scientific article published on 01 December 2019

Response to Pagano et al.

scientific article

Response to: Comment on "Effect of Riociguat and Sildenafil on Right Heart Remodeling and Function in Pressure Overload Induced Model of Pulmonary Arterial Banding"

scientific article published on 16 December 2018

Reversal of experimental pulmonary hypertension by PDGF inhibition

scientific article

Reverse remodeling -- paradigm shift in the treatment of pulmonary hypertension

scientific article

Rhodiola: an ordinary plant or a promising future therapy for pulmonary hypertension? a brief review

scientific article published on September 2013

Riociguat for pulmonary hypertension

scientific article published on March 2010

Riociguat for the treatment of pulmonary hypertension.

scientific article published on 11 March 2011

Role of Nox4 in murine models of kidney disease.

scientific article published on 27 June 2012

Role of Src tyrosine kinases in experimental pulmonary hypertension

scientific article published on 19 April 2012

Role of epidermal growth factor inhibition in experimental pulmonary hypertension.

scientific article published on 22 October 2009

Role of the prostanoid EP4 receptor in iloprost-mediated vasodilatation in pulmonary hypertension

scientific article published on 8 May 2008

Sestrin 2 protein regulates platelet-derived growth factor receptor β (Pdgfrβ) expression by modulating proteasomal and Nrf2 transcription factor functions

scientific article

Sestrin-2, a repressor of PDGFRβ signalling, promotes cigarette-smoke-induced pulmonary emphysema in mice and is upregulated in individuals with COPD.

scientific article published on 29 August 2013

Severe Emphysema in the SU5416/Hypoxia Rat Model of Pulmonary Hypertension

scientific article published on 01 August 2019

Shear force sensing of epithelial Na+ channel (ENaC) relies on N-glycosylated asparagines in the palm and knuckle domains of αENaC

scientific article published on 23 December 2019

Short-term improvement in pulmonary hemodynamics is strongly predictive of long-term survival in patients with pulmonary arterial hypertension

scientific article

Shroom expression is attenuated in pulmonary arterial hypertension.

scientific article

Sildenafil for long-term treatment of nonoperable chronic thromboembolic pulmonary hypertension

scientific article published on 24 January 2003

Sildenafil for treatment of lung fibrosis and pulmonary hypertension: a randomised controlled trial

scientific article published in September 2002

Sildenafil improves dynamic vascular function in the brain: studies in patients with pulmonary hypertension

scientific article published on 23 December 2005

Sildenafil in hypoxic pulmonary hypertension potentiates a compensatory up-regulation of NO-cGMP signaling

scientific article published in January 2008

Simultaneous analysis of 4- and 5-series lipoxygenase and cytochrome P450 products from different biological sources by reversed-phase high-performance liquid chromatographic technique

scientific article

Sixth Annual Scientific Workshops and Debates of the Pulmonary Vascular Research Institute (PVRI)

Smoking: Is it a Risk Factor for Pulmonary Vascular Diseases? ⬇️

scientific article published on October 1, 2012

Soluble guanylate cyclase stimulator riociguat and phosphodiesterase 5 inhibitor sildenafil ameliorate pulmonary hypertension due to left heart disease in mice.

scientific article

Sphingosine Kinase 1 Regulates Inflammation and Contributes to Acute Lung Injury in Pneumococcal Pneumonia via the Sphingosine-1-Phosphate Receptor 2.

scientific article published on 2 January 2018

Stimulation of soluble guanylate cyclase prevents cigarette smoke-induced pulmonary hypertension and emphysema

scientific article published in June 2014

Structural and functional prevention of hypoxia-induced pulmonary hypertension by individualized exercise training in mice

scientific article published on 4 April 2014

Subthreshold doses of specific phosphodiesterase type 3 and 4 inhibitors enhance the pulmonary vasodilatory response to nebulized prostacyclin with improvement in gas exchange

Suppression of adrenomedullin contributes to vascular leakage and altered epithelial repair during asthma

scientific article published on 12 June 2012

TASK-1 potassium channel is not critically involved in mediating hypoxic pulmonary vasoconstriction of murine intra-pulmonary arteries

scientific article

Targeting cancer with phosphodiesterase inhibitors

scientific article published on January 2010

Targeting cyclin-dependent kinases for the treatment of pulmonary arterial hypertension

scientific article published on 17 May 2019

Terguride ameliorates monocrotaline-induced pulmonary hypertension in rats

scientific article published on 14 October 2010

The Cytosolic NADPH Oxidase Subunit NoxO1 Promotes an Endothelial Stalk Cell Phenotype

scientific article

The Endoplasmic Reticulum Chaperone Calnexin Is a NADPH Oxidase NOX4 Interacting Protein

scientific article published on 9 February 2016

The Giessen Pulmonary Hypertension Registry: Survival in pulmonary hypertension subgroups

scientific article published on 17 February 2017

The NADPH Oxidase Nox2 Mediates Vitamin D-Induced Vascular Regeneration in Male Mice.

scientific article

The NADPH organizers NoxO1 and p47phox are both mediators of diabetes-induced vascular dysfunction in mice

scientific article

The NADPH oxidase Nox4 has anti-atherosclerotic functions

scientific article published on 17 September 2015

The PDE inhibitor zaprinast enhances NO-mediated protection against vascular leakage in reperfused lungs

scientific article published in September 2000

The Role of Transient Receptor Potential Channel 6 Channels in the Pulmonary Vasculature

scientific article

The lectin-like domain of tumor necrosis factor-alpha improves alveolar fluid balance in injured isolated rabbit lungs

scientific article published in May 2008

The role of classical transient receptor potential channels in the regulation of hypoxic pulmonary vasoconstriction.

scientific article published on January 2010

The role of dimethylarginine dimethylaminohydrolase (DDAH) in pulmonary fibrosis

scientific article published on January 2013

The role of dimethylarginine dimethylaminohydrolase in idiopathic pulmonary fibrosis

scientific article published on June 2011

The science of endothelin-1 and endothelin receptor antagonists in the management of pulmonary arterial hypertension: current understanding and future studies.

scientific article published on June 2009

The soluble guanylate cyclase activator HMR1766 reverses hypoxia-induced experimental pulmonary hypertension in mice.

scientific article published on 17 July 2009

The soluble guanylate cyclase stimulator riociguat ameliorates pulmonary hypertension induced by hypoxia and SU5416 in rats

scientific article

The soluble guanylate cyclase stimulator riociguat ameliorates pulmonary hypertension induced by hypoxia and SU5416 in rats.

scientific article

Therapeutic efficacy of TBC3711 in monocrotaline-induced pulmonary hypertension

scientific article

Therapeutic efficacy of azaindole-1 in experimental pulmonary hypertension

scientific article

Time course of cigarette smoke-induced changes of systemic inflammation and muscle structure

scientific article published on 22 May 2015

Treprostinil inhibits the recruitment of bone marrow-derived circulating fibrocytes in chronic hypoxic pulmonary hypertension.

scientific article published on 4 June 2010

Unchanged NADPH Oxidase Activity in Nox1-Nox2-Nox4 Triple Knockout Mice: What Do NADPH-Stimulated Chemiluminescence Assays Really Detect?

scientific article published on 23 April 2015

Update: Preclinical developments for the treatment of pulmonary arterial hypertension

scientific article published on 28 August 2009

Upregulation of NAD(P)H oxidase 1 in hypoxia activates hypoxia-inducible factor 1 via increase in reactive oxygen species

scientific article

Urodilatin, a natriuretic peptide stimulating particulate guanylate cyclase, and the phosphodiesterase 5 inhibitor dipyridamole attenuate experimental pulmonary hypertension: synergism upon coapplication.

scientific article

VEGF Receptor Inhibition As a Model of Pulmonary Hypertension in Mice ⬇️

scientific article published on November 15, 2011

Vasculotide reduces pulmonary hyperpermeability in experimental pneumococcal pneumonia.

scientific article published on 13 November 2017

Vaskuläre Effekte der alveolären Hypoxie - Sensor- und Signaltransduktionsmechanismen

scientific article published on 01 August 2002

Vaskuläre Folgeerkrankungen bei obstruktiver Schlafapnoe

scientific article published on 01 April 2006

Zardaverine and aerosolised iloprost in a model of acute respiratory failure

scientific article published in August 2003

[Inhalative strategies for improvement of pulmonary hemodynamics and gas exchange in sepsis and severe pulmonary hypertension]

scientific article

[Sleep apnea and cardiovascular disease--results from animal studies]

scientific article published on 25 October 2007

c-ANCA-induced neutrophil-mediated lung injury: a model of acute Wegener's granulomatosis

scientific article published on 23 December 2009

cAMP phosphodiesterase inhibitors increases nitric oxide production by modulating dimethylarginine dimethylaminohydrolases.

scientific article

cDNA array hybridization after laser-assisted microdissection from nonneoplastic tissue

scientific article

p38 MAPK Inhibition Improves Heart Function in Pressure Loaded Right Ventricular Hypertrophy

scientific article

sGC activators and stimulators attenuate ischemia/reperfusion injury of the lung.

scientific article

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