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List of works by Christophe Ginestier

A Recurrent Chromosome Breakpoint in Breast Cancer at theNRG1/Neuregulin 1/HeregulinGene

article

A genome-wide RNAi screen reveals essential therapeutic targets of breast cancer stem cells

scientific article published on 02 September 2019

A recurrent chromosome translocation breakpoint in breast and pancreatic cancer cell lines targets the neuregulin/NRG1 gene

scientific article published on August 2003

A stemness-related ZEB1-MSRB3 axis governs cellular pliancy and breast cancer genome stability.

scientific article

ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome

scientific article

ALDH1-positive cancer stem cells predict engraftment of primary breast tumors and are governed by a common stem cell program.

scientific article published on 18 October 2013

Aldehyde dehydrogenase 1 is a marker for normal and malignant human colonic stem cells (SC) and tracks SC overpopulation during colon tumorigenesis

scientific article

Aldehyde dehydrogenase 1-positive cancer stem cells mediate metastasis and poor clinical outcome in inflammatory breast cancer

scientific article

Aldehyde dehydrogenase and estrogen receptor define a hierarchy of cellular differentiation in the normal human mammary epithelium.

scientific article

An iron hand over cancer stem cells

scientific article published on 14 June 2017

BMI1 nuclear location is critical for RAD51-dependent response to replication stress and drives chemoresistance in breast cancer stem cells

scientific article published on 02 February 2022

Breast cancer cell lines contain functional cancer stem cells with metastatic capacity and a distinct molecular signature

scientific article (publication date: 15 February 2009)

Breast cancer stem cells are regulated by mesenchymal stem cells through cytokine networks

scientific article

Breast cancer stem cells programs: enter the (non)-code.

scientific article published on 8 March 2016

Breast cancer stem cells transition between epithelial and mesenchymal states reflective of their normal counterparts

scientific article published on 27 December 2013

Breast cancer stem cells: tools and models to rely on.

scientific article published on 25 June 2009

Brief reports: A distinct DNA methylation signature defines breast cancer stem cells and predicts cancer outcome

scientific article published on 01 November 2014

CD44 regulates epigenetic plasticity by mediating iron endocytosis

scientific article published on 03 August 2020

Cancer stem cell vaccination confers significant antitumor immunity

scientific article published in April 2012

Cancer stem cells in breast: current opinion and future challenges.

scientific article published on 10 June 2008

Comprehensive profiling of 8p11-12 amplification in breast cancer

scientific article published on December 2005

Computational Screening of Anti-Cancer Drugs Identifies a New BRCA Independent Gene Expression Signature to Predict Breast Cancer Sensitivity to Cisplatin

scientific article published on 13 May 2022

Correlated break at PARK2/FRA6E and loss of AF-6/Afadin protein expression are associated with poor outcome in breast cancer.

scientific article

Depleting MET-Expressing Tumor Cells by ADCC Provides a Therapeutic Advantage over Inhibiting HGF/MET Signaling

scientific article

ERBB2 phosphorylation and trastuzumab sensitivity of breast cancer cell lines.

scientific article published on 21 May 2007

ETV6 gene rearrangements in invasive breast carcinoma

scientific article published on 01 September 2005

Flick the cancer stem cells' switch to turn cancer off.

scientific article published on 28 April 2017

Frequency, prognostic impact, and subtype association of 8p12, 8q24, 11q13, 12p13, 17q12, and 20q13 amplifications in breast cancers

scientific article published on 13 October 2006

Gene expression profiling of breast cell lines identifies potential new basal markers.

scientific article

Gene expression profiling of colon cancer by DNA microarrays and correlation with histoclinical parameters

scientific article

Getting to the root of BRCA1-deficient breast cancer

scientific article published on 01 September 2009

Growth hormone is secreted by normal breast epithelium upon progesterone stimulation and increases proliferation of stem/progenitor cells

scientific article

Junctional recruitment of mammalian Scribble relies on E-cadherin engagement

scientific article (publication date: 23 June 2005)

Loss of FHIT protein expression is a marker of adverse evolution in good prognosis localized breast cancer.

scientific article published in December 2003

Mammary stem cell number as a determinate of breast cancer risk.

scientific article published on January 2007

Mevalonate metabolism regulates Basal breast cancer stem cells and is a potential therapeutic target.

scientific article published on July 2012

MicroRNA100 inhibits self-renewal of breast cancer stem-like cells and breast tumor development

scientific article

MicroRNA93 regulates proliferation and differentiation of normal and malignant breast stem cells.

scientific article

Moesin expression is a marker of basal breast carcinomas.

scientific article

Nectin-4 is a new histological and serological tumor associated marker for breast cancer

scientific article

Nectin-4: a new prognostic biomarker for efficient therapeutic targeting of primary and metastatic triple-negative breast cancer

scientific article

Poly(ADP-ribose) polymerase 1 (PARP1) overexpression in human breast cancer stem cells and resistance to olaparib.

scientific article published on 21 August 2014

Pregnane X-receptor promotes stem cell-mediated colon cancer relapse

scientific article published on 18 July 2016

Prognosis and gene expression profiling of 20q13-amplified breast cancers

scientific article published on 01 August 2006

Reciprocal translocations in breast tumor cell lines: cloning of a t(3;20) that targets the FHIT gene

scientific article

Salinomycin kills cancer stem cells by sequestering iron in lysosomes.

scientific article

TACC1-chTOG-Aurora A protein complex in breast cancer

scientific article

Targeted NGS, array-CGH, and patient-derived tumor xenografts for precision medicine in advanced breast cancer: a single-center prospective study

scientific article published on 18 October 2016

The histone deacetylase inhibitor abexinostat induces cancer stem cells differentiation in breast cancer with low Xist expression

scientific article published on 18 October 2013

Typical medullary breast carcinomas have a basal/myoepithelial phenotype.

scientific article published on November 2005

What drives breast cancer heterogeneity: oncogenic events or cell of origin?

scientific article published on 08 May 2012

[Molecular entities of the breast cancer: the difference is in the origin]

scientific article published on 12 October 2012

[Stem cells and epithelial cancers: the example of breast cancer]

scientific article published on 17 October 2008

[ZNF703: a novel oncogene involved in breast cancer]

scientific article published on 28 April 2011

miR-600 Acts as a Bimodal Switch that Regulates Breast Cancer Stem Cell Fate through WNT Signaling.

scientific article published in February 2017

p53 and cancer stem cells: The mevalonate connexion ⬇️

scientific article published on July 15, 2012

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