List of works - Toshitaka Matsui

A heme degradation enzyme, HutZ, from Vibrio cholerae

scientific article published on 24 May 2012

A new way to degrade heme: the Mycobacterium tuberculosis enzyme MhuD catalyzes heme degradation without generating CO.

scientific article published on 18 February 2013

Bach1, a heme-dependent transcription factor, reveals presence of multiple heme binding sites with distinct coordination structure

scientific article published on August 2007

Binding of oxygen and carbon monoxide to a heme-regulated phosphodiesterase from Escherichia coli. Kinetics and infrared spectra of the full-length wild-type enzyme, isolated PAS domain, and Met-95 mutants.

scientific article published on 11 November 2003

Characterization of Met95 mutants of a heme-regulated phosphodiesterase from Escherichia coli. Optical absorption, magnetic circular dichroism, circular dichroism, and redox potentials.

scientific article published in December 2003

Characterization of a direct oxygen sensor heme protein from Escherichia coli. Effects of the heme redox states and mutations at the heme-binding site on catalysis and structure.

scientific article published on 22 April 2002

Charge-state-distribution analysis of Bach2 intrinsically disordered heme binding region

scientific article published on 20 May 2016

Crystal structure of the dioxygen-bound heme oxygenase from Corynebacterium diphtheriae: implications for heme oxygenase function

scientific article

Crystallographic studies of heme oxygenase complexed with an unstable reaction intermediate, verdoheme.

scientific article published on 27 April 2012

Distinct reaction pathways followed upon reduction of oxy-heme oxygenase and oxy-myoglobin as characterized by Mössbauer spectroscopy.

scientific article

Enzymatic ring-opening mechanism of verdoheme by the heme oxygenase: a combined X-ray crystallography and QM/MM study

scientific article

Heme binds to an intrinsically disordered region of Bach2 and alters its conformation

scientific article

Heme degradation by Staphylococcus aureus IsdG and IsdI liberates formaldehyde rather than carbon monoxide.

scientific article published on 24 April 2013

Heme regulates B-cell differentiation, antibody class switch, and heme oxygenase-1 expression in B cells as a ligand of Bach2.

scientific article

Hydrogen sulfide bypasses the rate-limiting oxygen activation of heme oxygenase

scientific article published in Journal of Biological Chemistry

Kinetic isotope effects on the rate-limiting step of heme oxygenase catalysis indicate concerted proton transfer/heme hydroxylation

scientific article published on 01 December 2003

Ligand design for the improvement of stability of metal complex.protein hybrids

scientific article published on 24 October 2007

Light-Wavelength-Based Quantitative Control of Dihydrofolate Reductase Activity by Using a Photochromic Isostere of an Inhibitor

scientific article published on 03 April 2019

Mechanistic studies of the isomerization of peroxynitrite to nitrate catalyzed by distal histidine metmyoglobin mutants.

scientific article

O(2)- and H(2)O(2)-dependent verdoheme degradation by heme oxygenase: reaction mechanisms and potential physiological roles of the dual pathway degradation.

scientific article published on 22 August 2005

Proton transfer at helium temperatures during dioxygen activation by heme monooxygenases.

scientific article published in December 2004

Roles of distal Asp in heme oxygenase from Corynebacterium diphtheriae, HmuO: A water-driven oxygen activation mechanism.

scientific article published on 4 November 2004

Solution 1H NMR characterization of substrate-free C. diphtheriae heme oxygenase: pertinence for determining magnetic axes in paramagnetic substrate complexes

scientific article

Structure and catalytic mechanism of heme oxygenase.

scientific article published on 8 March 2007

Time-resolved small-angle X-ray scattering investigation of the folding dynamics of heme oxygenase: implication of the scaling relationship for the submillisecond intermediates of protein folding

scientific article published on 23 January 2006

Unique coupling of mono- and dioxygenase chemistries in a single active site promotes heme degradation

scientific article published on 22 March 2016

List of works by Toshitaka Matsui

A heme degradation enzyme, HutZ, from Vibrio cholerae

A new way to degrade heme: the Mycobacterium tuberculosis enzyme MhuD catalyzes heme degradation without generating CO.

Bach1, a heme-dependent transcription factor, reveals presence of multiple heme binding sites with distinct coordination structure

Binding of oxygen and carbon monoxide to a heme-regulated phosphodiesterase from Escherichia coli. Kinetics and infrared spectra of the full-length wild-type enzyme, isolated PAS domain, and Met-95 mutants.

Characterization of Met95 mutants of a heme-regulated phosphodiesterase from Escherichia coli. Optical absorption, magnetic circular dichroism, circular dichroism, and redox potentials.

Characterization of a direct oxygen sensor heme protein from Escherichia coli. Effects of the heme redox states and mutations at the heme-binding site on catalysis and structure.

Charge-state-distribution analysis of Bach2 intrinsically disordered heme binding region

Crystal structure of the dioxygen-bound heme oxygenase from Corynebacterium diphtheriae: implications for heme oxygenase function

Crystallographic studies of heme oxygenase complexed with an unstable reaction intermediate, verdoheme.

Distinct reaction pathways followed upon reduction of oxy-heme oxygenase and oxy-myoglobin as characterized by Mössbauer spectroscopy.

Enzymatic ring-opening mechanism of verdoheme by the heme oxygenase: a combined X-ray crystallography and QM/MM study

Heme binds to an intrinsically disordered region of Bach2 and alters its conformation

Heme degradation by Staphylococcus aureus IsdG and IsdI liberates formaldehyde rather than carbon monoxide.

Heme regulates B-cell differentiation, antibody class switch, and heme oxygenase-1 expression in B cells as a ligand of Bach2.

Hydrogen sulfide bypasses the rate-limiting oxygen activation of heme oxygenase

Kinetic isotope effects on the rate-limiting step of heme oxygenase catalysis indicate concerted proton transfer/heme hydroxylation

Ligand design for the improvement of stability of metal complex.protein hybrids

Light-Wavelength-Based Quantitative Control of Dihydrofolate Reductase Activity by Using a Photochromic Isostere of an Inhibitor

Mechanistic studies of the isomerization of peroxynitrite to nitrate catalyzed by distal histidine metmyoglobin mutants.

O(2)- and H(2)O(2)-dependent verdoheme degradation by heme oxygenase: reaction mechanisms and potential physiological roles of the dual pathway degradation.

Proton transfer at helium temperatures during dioxygen activation by heme monooxygenases.

Roles of distal Asp in heme oxygenase from Corynebacterium diphtheriae, HmuO: A water-driven oxygen activation mechanism.

Solution 1H NMR characterization of substrate-free C. diphtheriae heme oxygenase: pertinence for determining magnetic axes in paramagnetic substrate complexes

Structure and catalytic mechanism of heme oxygenase.

Time-resolved small-angle X-ray scattering investigation of the folding dynamics of heme oxygenase: implication of the scaling relationship for the submillisecond intermediates of protein folding

Unique coupling of mono- and dioxygenase chemistries in a single active site promotes heme degradation