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List of works by Ottmar Janssen

2-D DIGE analyses of enriched secretory lysosomes reveal heterogeneous profiles of functionally relevant proteins in leukemic and activated human NK cells

scientific article published in July 2008

2-D DIGE analysis of the proteome of extracts from peanut variants reveals striking differences in major allergen contents

scientific article

ADAM10 regulates FasL cell surface expression and modulates FasL-induced cytotoxicity and activation-induced cell death.

scientific article published on 9 February 2007

Activation-Induced T Cell Death: Resistance or Susceptibility Correlate with Cell Surface Fas Ligand Expression and T Helper Phenotype ⬇️

scientific article published on October 10, 1997

Binding of the intracellular Fas ligand (FasL) domain to the adaptor protein PSTPIP results in a cytoplasmic localization of FasL.

scientific article

Breakpoint characterization of the der(19)t(11;19)(q13;p13) in the ovarian cancer cell line SKOV-3.

scientific article published on 30 January 2013

Butyrophilin 3A/CD277-Dependent Activation of Human γδ T Cells: Accessory Cell Capacity of Distinct Leukocyte Populations.

scientific article published on 12 September 2016

CD95 ligand--death factor and costimulatory molecule?

scientific article

Cationic detergents enable the separation of membrane proteins of Plasmodium falciparum-infected erythrocytes by 2D gel electrophoresis

scientific article published in April 2012

Cell Communication and Signaling is becoming the official journal of the Signal Transduction Society

article by Stephan M Feller et al published 6 August 2008 in Cell Communication and Signaling

Characterization of Phleum pratense pollen extracts by 2-D DIGE and allergen immunoreactivity

scientific article published on 17 November 2010

Comparison of two genetically related Entamoeba histolytica cell lines derived from the same isolate with different pathogenic properties

scientific article

Complementary effects of HDAC inhibitor 4-PB on gap junction communication and cellular export mechanisms support restoration of chemosensitivity of PDAC cells

scientific article published on 12 December 2006

Considering Fas ligand as a target for therapy

scientific article

Death receptors and caspases: role in lymphocyte proliferation, cell death, and autoimmunity

scientific article

Degranulation of human cytotoxic lymphocytes is a major source of proteolytically active soluble CD26/DPP4

scientific article published on 12 July 2019

Detection and structural characterization of natural Ara h 7, the third peanut allergen of the 2S albumin family.

scientific article published in July 2010

Differential protein-protein interactions of full length human FasL and FasL fragments generated by proteolysis

scientific article published on 26 November 2013

Differential surface expression of ADAM10 and ADAM17 on human T lymphocytes and tumor cells

scientific article

Down-regulation of the cancer/testis antigen 45 (CT45) is associated with altered tumor cell morphology, adhesion and migration

scientific article published on 10 June 2013

Effector Granules in Human T Lymphocytes: Proteomic Evidence for Two Distinct Species of Cytotoxic Effector Vesicles

article

Effector granules in human T lymphocytes: the luminal proteome of secretory lysosomes from human T cells

scientific article published on 21 January 2011

Enrichment and analysis of secretory lysosomes from lymphocyte populations

scientific article

Fas ligand is localized to membrane rafts, where it displays increased cell death-inducing activity

scientific article

FasL cross-linking inhibits activation of human peripheral T cells

scientific article published on 30 March 2009

FasL expression and reverse signalling

scientific article published on January 2009

Functional Expression of NOD2 in Freshly Isolated Human Peripheral Blood γδ T Cells

Generation of soluble NKG2D ligands: proteolytic cleavage, exosome secretion and functional implications

scientific article published on August 2013

Granulysin species segregate to different lysosome-related effector vesicles (LREV) and get mobilized by either classical or non-classical degranulation

scientific article published on 16 January 2019

Identification of SH3 domain interaction partners of human FasL (CD178) by phage display screening

scientific article

Identification of SH3 domain proteins interacting with the cytoplasmic tail of the a disintegrin and metalloprotease 10 (ADAM10)

scientific article (publication date: 2014)

Identification of interaction partners for individual SH3 domains of Fas ligand associated members of the PCH protein family in T lymphocytes

scientific article

Identification of the complete expressed human TCR V gamma repertoire by flow cytometry ⬇️

scientific article published on 01 August 1997

Immunosurveillance by human γδ T lymphocytes: the emerging role of butyrophilins

scientific article published on 5 June 2017

In-depth immunophenotyping of patients with glioblastoma multiforme: Impact of steroid treatment

scientific article published on 8 August 2017

Insights into the molecular regulation of FasL (CD178) biology

scientific article published on 03 December 2010

Intracellular localization and transcriptional regulation of tumor necrosis factor (TNF) receptor-associated factor 4 (TRAF4)

scientific article (publication date: October 2002)

Isolation of erythrocytes infected with viable early stages of Plasmodium falciparum by flow cytometry

scientific article published on 7 November 2012

Lysosome-Related Effector Vesicles in T Lymphocytes and NK Cells

scientific article

Mechanistic peculiarities of activation-induced mobilization of cytotoxic effector proteins in human T cells

scientific article published on 24 January 2018

Meeting Report: Tumor Biology--How Signaling Processes Translate to Therapy

Meeting report: Signal transduction meets systems biology

scientific article published on 30 April 2012

Modulation of CD4+ T-cell activation by CD95 co-stimulation

scientific article published on 5 November 2010

NFkappaB activation by Fas is mediated through FADD, caspase-8, and RIP and is inhibited by FLIP.

scientific article published on August 2004

NKG2D- and T-cell receptor-dependent lysis of malignant glioma cell lines by human γδ T cells: Modulation by temozolomide and A disintegrin and metalloproteases 10 and 17 inhibitors

scientific article published on 10 December 2015

Nuclear death receptor TRAIL-R2 inhibits maturation of let-7 and promotes proliferation of pancreatic and other tumor cells

scientific article

Peanut varieties with reduced Ara h 1 content indicating no reduced allergenicity

scientific article published on March 2010

Posttranslational regulation of Fas ligand function.

scientific article published on 29 December 2008

Pro- and anti-apoptotic CD95 signaling in T cells

scientific article published on 8 April 2011

Regulation of FasL expression: a SH3 domain containing protein family involved in the lysosomal association of FasL

scientific article

Regulation of T-cell death-associated gene 51 (TDAG51) expression in human T-cells.

scientific article

Role of caspases in CD95-induced biphasic activation of acid sphingomyelinase

scientific article published on 16 February 2017

SDF1α-induced interaction of the adapter proteins Nck and HS1 facilitates actin polymerization and migration in T cells

scientific article published on 28 November 2014

Secretory lysosomes and their cargo in T and NK cells

scientific article published on 10 November 2006

Shedding of endogenous MHC class I-related chain molecules A and B from different human tumor entities: heterogeneous involvement of the "a disintegrin and metalloproteases" 10 and 17.

scientific article published on 18 April 2013

Signal transduction in the footsteps of goethe and schiller

scientific article published on 4 February 2009

Signal transduction, receptors, mediators and genes: younger than ever - the 13th meeting of the Signal Transduction Society focused on aging and immunology

scientific article

Signal transduction--receptors, mediators, and genes

scientific article published on 24 March 2009

Slowly getting a clue on CD95 ligand biology

scientific article published on October 2003

Storage, expression and function of Fas ligand, the key death factor of immune cells.

scientific article published on January 2008

Subcellular localization and activation of ADAM proteases in the context of FasL shedding in T lymphocytes

scientific article

TGF-β enhances the cytotoxic activity of Vδ2 T cells

scientific article published on 26 September 2018

TNF induced cleavage of HSP90 by cathepsin D potentiates apoptotic cell death

scientific article published on 3 October 2016

Tetraspanin 8 is an interactor of the metalloprotease meprin β within tetraspanin-enriched microdomains

scientific article published in 2016

The adapter protein Nck: role of individual SH3 and SH2 binding modules for protein interactions in T lymphocytes

scientific article

The adapter proteins ADAP and Nck cooperate in T cell adhesion

scientific article published on 24 April 2014

The adaptor protein Nck interacts with Fas ligand: Guiding the death factor to the cytotoxic immunological synapse

scholarly article

The challenge to quantify proteins with charge trains due to isoforms or conformers

scientific article published on 14 December 2011

The natural anticancer compounds rocaglamides inhibit the Raf-MEK-ERK pathway by targeting prohibitin 1 and 2

scientific article

The proteases HtrA2/Omi and UCH-L1 regulate TNF-induced necroptosis

scientific article published on 3 October 2013

Transcriptional regulation of mouse mast cell protease-2 by interleukin-15.

scientific article published on October 2009

Watching molecules talking to each other

scientific article published on 25 March 2008

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