Search filters

List of works by Christine Holt

14-3-3 proteins regulate retinal axon growth by modulating ADF/cofilin activity

scientific article published on April 2012

A critical window for cooperation and competition among developing retinotectal synapses

scientific article

A cytoskeletal platform for local translation in axons

scientific article published on 26 February 2008

A functional equivalent of endoplasmic reticulum and Golgi in axons for secretion of locally synthesized proteins

scientific article published on 22 October 2008

A molecular mechanism for the heparan sulfate dependence of slit-robo signaling

scientific article

A role for S1P signalling in axon guidance in the Xenopus visual system

scientific article published on 12 December 2007

ALS/FTD Mutation-Induced Phase Transition of FUS Liquid Droplets and Reversible Hydrogels into Irreversible Hydrogels Impairs RNP Granule Function

scientific article

Age-related changes underlie switch in netrin-1 responsiveness as growth cones advance along visual pathway

scientific article

Apoptotic pathway and MAPKs differentially regulate chemotropic responses of retinal growth cones

scientific article published in March 2003

Asymmetrical beta-actin mRNA translation in growth cones mediates attractive turning to netrin-1.

scientific article

Axon micro-dissection and transcriptome profiling reveals the in vivo RNA content of fully differentiated myelinated motor axons

scientific article published on 12 February 2020

Axon-Axon Interactions Regulate Topographic Optic Tract Sorting via CYFIP2-Dependent WAVE Complex Function.

scientific article published in March 2018

Axon-TRAP-RiboTag: Affinity Purification of Translated mRNAs from Neuronal Axons in Mouse In Vivo

scientific article published in January 2018

Axonal mRNA localization and local protein synthesis in nervous system assembly, maintenance and repair

scientific article published on 13 April 2012

Axonal mRNA translation in neurological disorders

scientific article published on 29 September 2020

Axonal mRNAs: characterisation and role in the growth and regeneration of dorsal root ganglion axons and growth cones

scientific article

Axonal protein synthesis and degradation are necessary for efficient growth cone regeneration

scientific article

B-type Eph receptors and ephrins induce growth cone collapse through distinct intracellular pathways

scientific article published on December 2003

Cadherin function is required for axon outgrowth in retinal ganglion cells in vivo.

scientific article published in November 1996

Cell biology in neuroscience: RNA-based mechanisms underlying axon guidance

scientific article published on September 2013

Cellular determination in the Xenopus retina is independent of lineage and birth date

scientific article

Chimeric integrins expressed in retinal ganglion cells impair process outgrowth in vivo

scientific article published in April 1995

Chondroitin sulfate disrupts axon pathfinding in the optic tract and alters growth cone dynamics

scientific article published in November 2002

Control of retinal growth and axon divergence at the chiasm: lessons from Xenopus.

scientific article

Coupling of NF-protocadherin signaling to axon guidance by cue-induced translation.

scientific article

Cue-Polarized Transport of β-actin mRNA Depends on 3'UTR and Microtubules in Live Growth Cones

scientific article published on 10 September 2018

Cytoplasmic polyadenylation and cytoplasmic polyadenylation element-dependent mRNA regulation are involved in Xenopus retinal axon development

scientific article

Dedication to Friedrich Bonhoeffer

article

Development

article

Differential requirement of F-actin and microtubule cytoskeleton in cue-induced local protein synthesis in axonal growth cones.

scientific article

Differing semaphorin 3A concentrations trigger distinct signaling mechanisms in growth cone collapse

scientific article published on June 2012

Dynamic Axonal Translation in Developing and Mature Visual Circuits

scientific article published on 15 June 2016

E3 ligase Nedd4 promotes axon branching by downregulating PTEN

scientific article

ESCRT-II controls retinal axon growth by regulating DCC receptor levels and local protein synthesis

scientific article

Early events in the embryogenesis of the vertebrate visual system: cellular determination and pathfinding

scientific article published on January 1990

Effects of intraocular tetrodotoxin on the development of the retinocollicular pathway in the Syrian hamster

scientific article published in April 1989

Electroporation of cDNA/Morpholinos to targeted areas of embryonic CNS in Xenopus

scientific article

Ena/VASP function in retinal axons is required for terminal arborization but not pathway navigation

scientific article

Endocytosis-dependent desensitization and protein synthesis-dependent resensitization in retinal growth cone adaptation

scientific article published on 09 January 2005

Ephrin-B2 and EphB1 mediate retinal axon divergence at the optic chiasm

scientific journal article

Erratum to: Differential requirement of F-actin and microtubule cytoskeleton in cue-induced local protein synthesis in axonal growth cones

scientific article published on 19 June 2015

Expression and herbimycin A-sensitive localization of pp125FAK in retinal growth cones

scientific article published in April 1996

Expression of UNC-5 in the developing Xenopus visual system

scientific article published in October 2002

Extracellular Engrailed participates in the topographic guidance of retinal axons in vivo

scientific article published on November 2009

FGF signaling and target recognition in the developing Xenopus visual system

scientific article published in November 1995

FUS Phase Separation Is Modulated by a Molecular Chaperone and Methylation of Arginine Cation-π Interactions.

scientific article published in April 2018

Fibroblast growth factor receptor signaling in Xenopus retinal axon extension

scientific article published in December 1998

Filopodyan: An open-source pipeline for the analysis of filopodia.

scientific article published on 31 July 2017

Function and regulation of local axonal translation

scientific article published on February 2008

Growth Cone Tctp Is Dynamically Regulated by Guidance Cues

scholarly article by Cláudio Gouveia Roque published in January 2018

Growth factors: a role in guiding axons?

scientific article published on November 1997

Hermes Regulates Axon Sorting in the Optic Tract by Post-Trancriptional Regulation of Neuropilin 1

scientific article published on 9 November 2016

Imaging Axon Pathfinding in Xenopus In Vivo ⬇️

scientific article published on September 1, 2012

Imaging Axon Pathfinding in Zebrafish In Vivo: Figure 1 ⬇️

scientific article published on September 1, 2012

Introducing Open Biology

scientific article published on 20 July 2011

Introduction to the special issue on local protein synthesis in axons

Late Endosomes Act as mRNA Translation Platforms and Sustain Mitochondria in Axons

scientific article published on 03 January 2019

Live visualization of protein synthesis in axonal growth cones by microinjection of photoconvertible Kaede into Xenopus embryos

scientific article published on January 2008

Local translation and directional steering in axons

scientific article published on 26 July 2007

Local translation and mRNA trafficking in axon pathfinding

scientific article published on January 2009

Local translation in neurons: visualization and function

scientific article published on 03 July 2019

Local translation of extranuclear lamin B promotes axon maintenance

scientific article published in February 2012

Local translation of mRNAs in neural development ⬇️

scientific article published on October 19, 2010

Mechanosensing is critical for axon growth in the developing brain

scientific article published on 19 September 2016

Molecular control of local translation in axon development and maintenance

scientific article published on 14 March 2018

NF-Protocadherin Regulates Retinal Ganglion Cell Axon Behaviour in the Developing Visual System

scientific article published on 21 October 2015

NF-protocadherin and TAF1 regulate retinal axon initiation and elongation in vivo

scientific article published on January 2008

Navigational errors made by growth cones without filopodia in the embryonic Xenopus brain

scientific article

Neurobiology. Slit, the midline repellent

scientific article published in April 1999

New views on retinal axon development: a navigation guide

scientific article

Noncanonical Modulation of the eIF2 Pathway Controls an Increase in Local Translation during Neural Wiring

scientific article published on 27 December 2018

On-Site Ribosome Remodeling by Locally Synthesized Ribosomal Proteins in Axons

scientific article published on 01 December 2019

Outsourcing CREB translation to axons to survive.

scientific article published in February 2008

Overexpression of c-src and n-src in the developing Xenopus retina differentially impairs axonogenesis

scientific article published in January 1997

Position, guidance, and mapping in the developing visual system

scientific article published on October 1993

Postnatal changes in the uncrossed retinal projection of pigmented and albino syrian hamsters and the effects of monocular enucleation

scientific article published on 01 June 1995

Protein synthesis dependence of growth cone collapse induced by different Nogo-A-domains

scientific article published on 29 January 2014

RNA Docking and Local Translation Regulate Site-Specific Axon Remodeling In Vivo

scientific article published on 2 August 2017

RNA translation in axons

scientific article published in January 2004

RNA-binding protein Hermes/RBPMS inversely affects synapse density and axon arbor formation in retinal ganglion cells in vivo

scientific article

RNA-binding protein Vg1RBP regulates terminal arbor formation but not long-range axon navigation in the developing visual system

scientific article published on 11 September 2013

RNA-binding proteins and translational regulation in axons and growth cones

scientific article published on 23 May 2013

Rab5 and Rab4 regulate axon elongation in the Xenopus visual system.

scientific article published on January 2014

Rapid Cue-Specific Remodeling of the Nascent Axonal Proteome

scientific article published on 28 June 2018

Rapid changes in tissue mechanics regulate cell behaviour in the developing embryonic brain

scientific article published on 15 January 2019

Receptor-specific interactome as a hub for rapid cue-induced selective translation in axons

scientific article published on 20 November 2019

Regulation of chemotropic guidance of nerve growth cones by microRNA.

scientific article published on 3 November 2011

Remote control of gene function by local translation

scientific article

Retinal axon guidance: novel mechanisms for steering

scientific article published on February 2004

Role of microRNAs in Semaphorin function and neural circuit formation

scientific article published on 05 December 2012

SFRP1 regulates the growth of retinal ganglion cell axons through the Fz2 receptor

scientific article published on 18 September 2005

Signaling mechanisms underlying Slit2-induced collapse of Xenopus retinal growth cones

scientific article

Single Molecule Translation Imaging Visualizes the Dynamics of Local β-Actin Synthesis in Retinal Axons.

scientific article

Single-molecule analysis of endogenous β-actin mRNA trafficking reveals a mechanism for compartmentalized mRNA localization in axons

article published in the Proceedings of the National Academy of Sciences of the United States of America

Specific heparan sulfate structures involved in retinal axon targeting.

scientific article published in January 2002

Subcellular mRNA localization in animal cells and why it matters

scientific article

Subcellular profiling reveals distinct and developmentally regulated repertoire of growth cone mRNAs.

scientific article

Sugar codes for axons?

scientific article

Targeted Electroporation in the CNS in Xenopus Embryos

scientific article published on 01 January 2018

Tctp in Neuronal Circuitry Assembly

scientific article published in January 2017

The central dogma decentralized: new perspectives on RNA function and local translation in neurons

scientific article

The role of cyclic nucleotides in axon guidance

scientific article published on January 2007

The structure and global distribution of the endoplasmic reticulum network are actively regulated by lysosomes

scientific article published on 16 December 2020

The topography of the initial retinotectal projection.

scientific article published in January 1983

The transcription factor Engrailed-2 guides retinal axons

scientific article

Topographic mapping in dorsoventral axis of the Xenopus retinotectal system depends on signaling through ephrin-B ligands

scientific article

Total internal reflection fluorescence anisotropy imaging microscopy: setup, calibration, and data processing for protein polymerization measurements in living cells

scientific article

Transcriptome analysis of embryonic and adult sensory axons reveals changes in mRNA repertoire localization

scientific article published on 23 November 2010

Translational regulation in growth cones

scientific article published on 27 April 2011

Tsukushi functions as an organizer inducer by inhibition of BMP activity in cooperation with chordin.

scientific article published in September 2004

Tumor protein Tctp regulates axon development in the embryonic visual system

scientific article published on 22 February 2016

Turning of retinal growth cones in a netrin-1 gradient mediated by the netrin receptor DCC.

scientific article published in December 1997

Xenopus Sprouty2 inhibits FGF-mediated gastrulation movements but does not affect mesoderm induction and patterning

scientific article

cAMP-dependent growth cone guidance by netrin-1.

scientific article

miR-124 acts through CoREST to control onset of Sema3A sensitivity in navigating retinal growth cones.

scientific article published on 4 December 2011

miR-182 Regulates Slit2-Mediated Axon Guidance by Modulating the Local Translation of a Specific mRNA.

scientific article

Paulina is supported by:

About Paulina

Help