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List of works by Takeshi Omasa

A cDNA from human bone marrow encoding a protein exhibiting homology to the ATP1gamma1/PLM/MAT8 family of transmembrane proteins.

scientific article

A comparison of various methods to predict bacterial predilection for organic solvents used as reaction media.

scientific article published in October 2008

Action of reactive oxygen species in the antifungal mechanism of gemini-pyridinium salts against yeast

scientific article published on 01 June 2012

Amplified gene location in chromosomal DNA affected recombinant protein production and stability of amplified genes.

scientific article

An MDCK cell culture-derived formalin-inactivated influenza virus whole-virion vaccine from an influenza virus library confers cross-protective immunity by intranasal administration in mice

scientific article

An attempt to add biological functions by genetic engineering in order to produce high-performance bioreactor cells for hybrid artificial liver: transfection of glutamine synthetase into Chinese hamster ovary (CHO) cell

scientific article published on 01 September 1997

Analysis of intracellular IgG secretion in Chinese hamster ovary cells to improve IgG production

scientific article published on 13 July 2018

Analysis of the immunoglobulin G (IgG) secretion efficiency in recombinant Chinese hamster ovary (CHO) cells by using Citrine-fusion IgG

scientific article published on 04 January 2019

Application of Unfolded Protein Response for Production of Biologics

scientific article published on January 2016

Approaches to Quality Risk Management When Using Single-Use Systems in the Manufacture of Biologics

scientific article

Artificial mimicking of physiological active transport by a membrane co-cultured with two different cells: hepatic origin HepG2 and renal origin PCTL-MDR.

scientific article published on September 2002

Atorvastatin Inhibits the HIF1α-PPAR Axis, Which Is Essential for Maintaining the Function of Human Induced Pluripotent Stem Cells

scientific article published on 19 June 2018

Bacterial artificial chromosome library for genome-wide analysis of Chinese hamster ovary cells

scientific article published in December 2009

Build-up functionalization of anti-EGFR × anti-CD3 bispecific diabodies by integrating high-affinity mutants and functional molecular formats

scientific article published on 18 March 2020

Cell engineering and cultivation of chinese hamster ovary (CHO) cells

scientific article published on April 2010

Construction and evaluation of drug-metabolizing cell line for bioartificial liver support system.

scientific article

Construction of BAC-based physical map and analysis of chromosome rearrangement in Chinese hamster ovary cell lines.

scientific article

Construction of membrane-anchoring fusion protein of Thermococcus kodakaraensis glycerol kinase and its application to repetitive batchwise reactions.

scientific article

Decrease in antithrombin III fucosylation by expressing GDP-fucose transporter siRNA in Chinese hamster ovary cells.

scientific article published in August 2008

Dedifferentiated fat cells differentiate into osteoblasts in titanium fiber mesh

scientific article

Development of a Continuous Bioconversion System Using a Thermophilic Whole-Cell Biocatalyst ⬇️

scientific article published on January 18, 2013

Development of a bioartificial liver with glutamine synthetase-transduced recombinant human hepatoblastoma cell line, HepG2.

scientific article

Double-compartment cell culture apparatus: construction and biochemical evaluation for bioartificial liver support.

scientific article published on January 2006

Effect of cell-surface hydrophobicity on bacterial conversion of water-immiscible chemicals in two-liquid-phase culture systems.

scientific article published in August 2009

Effect of sulfur sources on specific desulfurization activity of Rhodococcus erythropolis KA2-5-1 in exponential fed-batch culture.

scientific article published in March 2005

Effects of lactate concentration on hybridoma culture in lactate-controlled fed-batch operation

scientific article published on 01 March 1992

Efficient enrichment of high-producing recombinant Chinese hamster ovary cells for monoclonal antibody by flow cytometry.

scientific article

Efficient production of desulfurizing cells with the aid of expert system.

scientific article published in June 2000

Electron microscopic analysis of heat-induced leakage of polyphosphate from a phoU mutant of Escherichia coli

scientific article published on 07 April 2010

Enhanced IgG1 production by overexpression of nuclear factor kappa B inhibitor zeta (NFKBIZ) in Chinese hamster ovary cells.

scientific article published on 29 November 2017

Enhancement effects of BSA and linoleic acid on hybridoma cell growth and antibody production

scientific article published on 01 January 1994

Enhancement of antibody production by growth factor addition in perfusion and hollow-fiber culture systems

scientific article published on 01 December 1995

Enhancement of sialylation on humanized IgG-like bispecific antibody by overexpression of α2,6-sialyltransferase derived from Chinese hamster ovary cells.

scientific article

Flow cytometry: an improved method for the selection of highly productive gene-amplified CHO cells using flow cytometry.

scientific article

Fluorescence in situ hybridization using bacterial artificial chromosome (BAC) clones for the analysis of chromosome rearrangement in Chinese hamster ovary cells

scientific article published on 11 November 2011

Fluorescence polarization study of a salt bridge between a single chain Fv and its antigen ribonuclease A

scientific article published on 01 August 1997

Fluorescence polarization study of a salt bridge between a single-chain Fv and its antigen ribonuclease A

scientific article published on 01 July 1997

Gene amplification and its application in cell and tissue engineering

scientific article published in January 2002

Generation of high-producing cell lines by overexpression of cell division cycle 25 homolog A in Chinese hamster ovary cells.

scientific article published on 27 June 2013

Genome sequence comparison between Chinese hamster ovary (CHO) DG44 cells and mouse using end sequences of CHO BAC clones based on BAC-FISH results

scientific article published on 09 July 2018

Glycosylation analysis of an aggregated antibody produced by Chinese hamster ovary cells in bioreactor culture

scientific article published on 08 December 2013

Glycosylation pattern of humanized IgG-like bispecific antibody produced by recombinant CHO cells

scientific article published on 4 August 2009

Hyaluronic acid production by recombinant Streptococcus thermophilus.

scientific article published on 2 March 2011

Identification and analysis of specific chromosomal region adjacent to exogenous Dhfr-amplified region in Chinese hamster ovary cell genome

scientific article

Identification of regulatory motifs in the CHO genome for stable monoclonal antibody production

scientific article published on 20 August 2016

Improved antibody production in Chinese hamster ovary cells by ATF4 overexpression

scientific article published on 13 September 2013

Improved gene amplification by cell-cycle engineering combined with the Cre-loxP system in Chinese hamster ovary cells

scientific article

Improved production of recombinant human antithrombin III in Chinese hamster ovary cells by ATF4 overexpression.

scientific article published on June 2008

Improved recombinant antibody production by CHO cells using a production enhancer DNA element with repeated transgene integration at a predetermined chromosomal site

scientific article published on 14 November 2016

Improvement of Intracellular Traffic System by Overexpression of KDEL Receptor 1 in Antibody-Producing CHO Cells

scientific article published on 19 February 2020

Increase in desulfurization activity of Rhodococcus erythropolis KA2-5-1 using ethanol feeding

scientific article published in January 2000

Increased recombinant protein production owing to expanded opportunities for vector integration in high chromosome number Chinese hamster ovary cells.

scientific article published on 2 February 2016

Inhibition of CYP3A4 by 6′,7′-dihydroxybergamottin in human CYP3A4 over-expressed hepG2 cells ⬇️

scientific article published on August 2, 2012

Lengthening of high-yield production levels of monoclonal antibody-producing Chinese hamster ovary cells by downregulation of breast cancer 1.

scientific article published on 12 October 2016

Metabolic analysis of antibody producing Chinese hamster ovary cell culture under different stresses conditions.

scientific article published on 20 January 2016

Molecular cloning and sequencing of the human heme-regulated eukaryotic initiation factor 2 alpha (eIF-2 alpha) kinase from bone marrow culture

scientific article (publication date: June 2002)

Mutation in the sdeS Gene Promotes Expression of the sdeAB Efflux Pump Genes and Multidrug Resistance in Serratia marcescens ⬇️

scientific article published on March 21, 2011

N-linked glycan structures of a mouse monoclonal antibody produced from tobacco BY2 suspension-cultured cells

scientific article published in March 2006

N-terminal vacuolar sorting signal at the mouse antibody alters the N-linked glycosylation pattern in suspension-cultured tobacco BY2 cells ⬇️

scientific article published on July 30, 2011

Neuraminidase gene homology contributes to the protective activity of influenza vaccines prepared from the influenza virus library.

scientific article

Optimization of cell line development in the GS-CHO expression system using a high-throughput, single cell-based clone selection system

scientific article

Overexpression of GADD34 enhances production of recombinant human antithrombin III in Chinese hamster ovary cells.

scientific article

Overexpression of mutant cell division cycle 25 homolog B (CDC25B) enhances the efficiency of selection in Chinese hamster ovary cells.

scientific article published on 19 November 2013

Preface

scientific article published on 01 May 2012

Production of 2-deoxyribose 5-phosphate from fructose to demonstrate a potential of artificial bio-synthetic pathway using thermophilic enzymes.

scientific article published on 11 June 2010

Production of mouse monoclonal antibody with galactose-extended sugar chain by suspension cultured tobacco BY2 cells expressing human beta(1,4)-galactosyltransferase

scientific article published on 19 April 2007

Rapid Colorimetric Antibody Detection Using a Dual-function Peptide Probe for Silver Nanoparticle Aggregation and Antibody Recognition.

scientific article

Rapid construction of transgene-amplified CHO cell lines by cell cycle checkpoint engineering ⬇️

scientific article published on April 25, 2013

Rapid evaluation of N-glycosylation status of antibodies with chemiluminescent lectin-binding assay.

scientific article published on 23 December 2014

Rearranging the domain order of a diabody-based IgG-like bispecific antibody enhances its antitumor activity and improves its degradation resistance and pharmacokinetics

scientific article

Recognition of culture state using two-dimensional gel electrophoresis with an artificial neural network

scientific article published in July 2006

Secretion analysis of intracellular "difficult-to-express" immunoglobulin G (IgG) in Chinese hamster ovary (CHO) cells

scientific article published on 12 January 2019

Secretory leakage of IgG1 aggregates from recombinant Chinese hamster ovary cells

scientific article published on 21 December 2018

Single-cell transcriptome analyses reveal heterogeneity in suspension cultures and clonal markers of CHO-K1 cells

scientific article published on 12 November 2020

Stabilization of water-in-oil emulsion by Rhodococcus opacus B-4 and its application to biotransformation.

scientific article

Synergistic Photobactericidal Activity Based on Ultraviolet-A Irradiation and Ferulic Acid Derivatives

scientific article

Synergistic antimicrobial activity based on the combined use of a gemini-quaternary ammonium compound and ultraviolet-A light.

scientific article published on 4 December 2013

Synthesis and biological activity of thiazolyl-acetic acid derivatives as possible antimicrobial agents.

scientific article published on January 2013

Synthesis of thiazole derivatives and evaluation of their antiamoebic activity and cytotoxicity

scientific article published in January 2013

Systematic screening of Escherichia coli single-gene knockout mutants for improving recombinant whole-cell biocatalysts.

scientific article published on 12 March 2010

The Fab portion of immunoglobulin G contributes to its binding to Fcγ receptor III

scientific article published on 16 August 2019

The Healing Effect of Human Milk Fat Globule-EGF Factor 8 Protein (MFG-E8) in A Rat Model of Parkinson's Disease

scientific article published on 31 August 2018

The enhancement of antibody concentration and achievement of high cell density CHO cell cultivation by adding nucleoside.

scientific article published on 2 March 2017

The enhancement of specific antibody production rate in glucose- and glutamine-controlled fed-batch culture

scientific article published on 01 January 1992

The osteoblastic differentiation ability of human dedifferentiated fat cells is higher than that of adipose stem cells from the buccal fat pad.

scientific article

Trehalose suppresses antibody aggregation during the culture of Chinese hamster ovary cells.

scientific article published on 04 December 2013

Two routes of MexS-MexT-mediated regulation of MexEF-OprN and MexAB-OprM efflux pump expression in Pseudomonas aeruginosa.

scientific article published in April 2013

Utilization of hydrophobic bacterium Rhodococcus opacus B-4 as whole-cell catalyst in anhydrous organic solvents

scientific article published on 23 November 2006

Violacein improves recombinant IgG production by controlling the cell cycle of Chinese hamster ovary cells

scientific article published on 23 November 2020

What Kind of Signaling Maintains Pluripotency and Viability in Human-Induced Pluripotent Stem Cells Cultured on Laminin-511 with Serum-Free Medium?

scientific article

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