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List of works by Victor Mangas-Sanjuan

A multilevel object-oriented modelling methodology for physiologically-based pharmacokinetics (PBPK): Evaluation with a semi-mechanistic pharmacokinetic model

scientific article published on 09 January 2020

A promising camptothecin derivative: Semisynthesis, antitumor activity and intestinal permeability.

scientific article

Agitation Rate and Time for Complete Dissolution in BCS Biowaivers Based on Investigation of a BCS Biowaiver for Dexketoprofen Tablets.

scientific article published on 3 August 2015

Assessment of the Inter-Batch Variability of Microstructure Parameters in Topical Semisolids and Impact on the Demonstration of Equivalence

scientific article published on 01 October 2019

Assessment of the Regulatory Methods for the Comparison of Highly Variable Dissolution Profiles.

scientific article published on 29 August 2016

Commentary on the MID3 Good Practices Paper

scientific article

Comparison of free software platforms for the calculation of the 90% confidence interval of f2 similarity factor by bootstrap analysis

scientific article published on 10 February 2020

Computer simulations for bioequivalence trials: Selection of analyte in BCS class II and IV drugs with first-pass metabolism, two metabolic pathways and intestinal efflux transporter

scientific article published on 13 February 2018

Cyclometalated Iminophosphorane Gold(III) and Platinum(II) Complexes. A Highly Permeable Cationic Platinum(II) Compound with Promising Anticancer Properties

scientific article

Defining level A IVIVC dissolution specifications based on individual in vitro dissolution profiles of a controlled release formulation

scientific article published on 19 April 2018

Drug Penetration Across the blood–brain Barrier: an Overview ⬇️

scientific article published on October 1, 2010

Drug gastrointestinal absorption in rat: Strain and gender differences

scientific article published on 27 July 2015

Enhancing Oral Absorption of β-Lapachone: Progress Till Date.

scientific article

IVIVC approach based on carbamazepine bioequivalence studies combination

scientific article published in August 2017

In Silico Prediction of Caco-2 Cell Permeability by a Classification QSAR Approach

scientific article

In vitro-in situ permeability and dissolution of fexofenadine with kinetic modeling in the presence of sodium dodecyl sulfate

scientific article published on 11 August 2011

In vitro-in vivo correlations: general concepts, methodologies and regulatory applications

scientific article published on 02 July 2015

Intestinal Permeability of β-Lapachone and Its Cyclodextrin Complexes and Physical Mixtures

scientific article published on 24 November 2015

Investigating the Discriminatory Power of BCS-Biowaiver in Vitro Methodology to Detect Bioavailability Differences between Immediate Release Products Containing a Class I Drug.

scientific article published on 19 August 2015

Ion-pair strategy for enabling amifostine oral absorption: rat in situ and in vivo experiments.

scientific article published on 2 May 2013

Modified nonsink equation for permeability estimation in cell monolayers: comparison with standard methods.

scientific article published on 7 April 2014

Pharmacokinetics of Intravitreal Anti-VEGF Drugs in Age-Related Macular Degeneration

scientific article published on 31 July 2019

Population pharmacokinetic model of lithium and drug compliance assessment

scientific article published on 16 November 2016

Population pharmacokinetic/pharmacodynamic modelling of the effects of axomadol and its O-demethyl metabolite on pupil diameter and nociception in healthy subjects

scientific article published on 29 February 2016

Semi-mechanistic Pharmacokinetic/Pharmacodynamic model of three pegylated rHuEPO and ior®EPOCIM in New Zealand rabbits.

scientific article published on 2 May 2018

Semi-physiologic model validation and bioequivalence trials simulation to select the best analyte for acetylsalicylic acid.

scientific article

Semimechanistic cell-cycle type-based pharmacokinetic/pharmacodynamic model of chemotherapy-induced neutropenic effects of diflomotecan under different dosing schedules.

scientific article published on 6 May 2015

Semisynthesis, cytotoxic activity, and oral availability of new lipophilic 9-substituted camptothecin derivatives.

scientific article

Systematic modelling and design evaluation of unperturbed tumour dynamics in xenografts

scientific article published on 24 April 2018

Target-Site Investigation for the Plasma Prolactin Response: Mechanism-Based Pharmacokinetic-Pharmacodynamic Analysis of Risperidone and Paliperidone in the Rat.

scientific article published on 11 November 2016

Topiramate pharmacokinetics in neonates undergoing therapeutic hypothermia and proposal of an optimised dosing schedule

scientific article published on 22 August 2019

Tubulin acetylation promoting potency and absorption efficacy of deacetylase inhibitors.

scientific article

Validation of a semi-physiological model for caffeine in healthy subjects and cirrhotic patients.

scientific article published on 2 April 2015

Variability of permeability estimation from different protocols of subculture and transport experiments in cell monolayers.

scientific article published on 26 November 2014

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