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List of works by Hayley S. Ramshaw

14-3-3:Shc scaffolds integrate phosphoserine and phosphotyrosine signaling to regulate phosphatidylinositol 3-kinase activation and cell survival.

scientific article

14-3-3ε and ζ regulate neurogenesis and differentiation of neuronal progenitor cells in the developing brain.

scientific article

14-3-3ζ coordinates adipogenesis of visceral fat.

scientific article published on 29 July 2015

14-3-3ζ deficient mice in the BALB/c background display behavioural and anatomical defects associated with neurodevelopmental disorders

scientific article

14-3-3ζ regulates the mitochondrial respiratory reserve linked to platelet phosphatidylserine exposure and procoagulant function

scientific article published on 27 September 2016

A Negative Regulatory Mechanism Involving 14-3-3ζ Limits Signaling Downstream of ROCK to Regulate Tissue Stiffness in Epidermal Homeostasis.

scientific article published on December 2015

A Phase 1 study of the safety, pharmacokinetics and anti-leukemic activity of the anti-CD123 monoclonal antibody CSL360 in relapsed, refractory or high-risk acute myeloid leukemia

scientific article published on 20 November 2014

Chronic myelomonocytic leukemia requires granulocyte-macrophage colony-stimulating factor for growth in vitro and in vivo

scientific article published on 01 October 2002

Corrigendum: 14-3-3ζ regulates the mitochondrial respiratory reserve linked to platelet phosphatidylserine exposure and procoagulant function.

scientific article published on 30 August 2017

Efficacy of an Fc-modified anti-CD123 antibody (CSL362) combined with chemotherapy in xenograft models of acute myelogenous leukemia in immunodeficient mice

scientific article published on July 2015

Growth factor pleiotropy is controlled by a receptor Tyr/Ser motif that acts as a binary switch

scientific article

High CD123 levels enhance proliferation in response to IL-3, but reduce chemotaxis by downregulating CXCR4 expression

Immune insufficiency during GVHD is due to defective antigen presentation within dendritic cell subsets

scientific article published on 13 March 2012

In-vivo administration of clozapine affects behaviour but does not reverse dendritic spine deficits in the 14-3-3ζ KO mouse model of schizophrenia-like disorders.

scientific article published on 9 September 2015

Interleukin-3-mediated regulation of β-catenin in myeloid transformation and acute myeloid leukemia

scientific article published on 5 March 2014

Jak2V617F driven myeloproliferative neoplasm occurs independently of interleukin-3 receptor beta common signaling

scientific article published on 20 November 2015

Locomotor hyperactivity in 14-3-3ζ KO mice is associated with dopamine transporter dysfunction.

scientific article

MicroRNA-194 Promotes Prostate Cancer Metastasis by Inhibiting SOCS2.

scientific article published on 23 December 2016

Molecular basis of cytokine receptor activation

scientific article published on July 2010

Monoclonal antibody BB9 raised against bone marrow stromal cells identifies a cell-surface glycoprotein expressed by primitive human hemopoietic progenitors.

scientific article

Monoclonal antibody targeting of IL-3 receptor α with CSL362 effectively depletes CML progenitor and stem cells

scientific article published on 20 December 2013

Monoclonal antibody-mediated targeting of CD123, IL-3 receptor alpha chain, eliminates human acute myeloid leukemic stem cells

scientific article

Neuropilin-2 genomic elements drive cre recombinase expression in primitive blood, vascular and neuronal lineages

scientific article published on 24 October 2015

New approaches in the treatment of asthma.

scientific article

Role of the β Common (βc) Family of Cytokines in Health and Disease

scientific article

Sphingosine kinase regulates the rate of endothelial progenitor cell differentiation

scientific article published on 24 December 2008

Stem cell engraftment and cell cycle phenotype

scientific article published on 01 April 1999

Targeting of acute myeloid leukemia in vitro and in vivo with an anti-CD123 mAb engineered for optimal ADCC.

scientific article published on 7 April 2014

Targeting sphingosine kinase 1 induces MCL1-dependent cell death in acute myeloid leukemia

scientific article published on 12 December 2016

The GM-CSF receptor family: mechanism of activation and implications for disease

scientific article published on 18 January 2012

The Shc-binding site of the betac subunit of the GM-CSF/IL-3/IL-5 receptors is a negative regulator of hematopoiesis

scientific article

The phosphoserine-585-dependent pathway of the GM-CSF/IL-3/IL-5 receptors mediates hematopoietic cell survival through activation of NF-kappaB and induction of bcl-2.

scientific article published on 14 August 2003

The structure of the GM-CSF receptor complex reveals a distinct mode of cytokine receptor activation

scientific article

Ywhaz/14-3-3ζ Deletion Improves Glucose Tolerance Through a GLP-1-Dependent Mechanism

scientific article published on 11 May 2016

miR-155 as a potential target of IL-3 signaling in primary AML cells

scientific article published on 4 March 2017

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