Search filters

List of works by Rocío García-Carbonero

A critical review of HER2-positive gastric cancer evaluation and treatment: from trastuzumab, and beyond

scientific article

A phase I trial of daily oral 4'- N -benzoyl-staurosporine in combination with protracted continuous infusion 5-fluorouracil in patients with advanced solid malignancies.

scientific article

A phase II and pharmacokinetic study of ecteinascidin 743 in patients with gastrointestinal stromal tumors.

scientific article

A randomized phase II study to compare oxaliplatin plus 5-fluorouracil and leucovorin (FOLFOX4) versus oxaliplatin plus raltitrexed (TOMOX) as first-line chemotherapy for advanced colorectal cancer

scientific article

An open-label phase II study evaluating the safety and efficacy of ramucirumab combined with mFOLFOX-6 as first-line therapy for metastatic colorectal cancer.

scientific article published on 27 March 2014

Analysis of Angiogenesis Biomarkers for Ramucirumab Efficacy in Patients with Metastatic Colorectal Cancer from RAISE, a Global, Randomized, Double-Blind, Phase III Study

scientific article published on 7 December 2017

Antibiotics and growth factors in the management of fever and neutropenia in cancer patients.

scientific article

Baseline carcinoembryonic antigen as a predictive factor of ramucirumab efficacy in RAISE, a second-line metastatic colorectal carcinoma phase III trial

scientific article published on 13 April 2017

Clinical management of regorafenib in the treatment of patients with advanced colorectal cancer

scientific article

Comprehensive Plasma Metabolomic Profile of Patients with Advanced Neuroendocrine Tumors (NETs). Diagnostic and Biological Relevance

scientific article published on 27 May 2021

Correction: Dasatinib, a Src inhibitor, sensitizes liver metastatic colorectal carcinoma to oxaliplatin in tumors with high levels of phospho-Src

scientific article published on November 2016

Current perspectives on the clinical experience, pharmacology, and continued development of the camptothecins.

scientific article

DICER1, DROSHA and miRNAs in patients with non-small cell lung cancer: implications for outcomes and histologic classification

scientific article published on 24 January 2013

Dasatinib, a Src inhibitor, sensitizes liver metastatic colorectal carcinoma to oxaliplatin in tumors with high levels of phospho-Src

scientific article published on 20 April 2016

Description of the genetic variants identified in a cohort of patients diagnosed with localized anal squamous cell carcinoma and treated with panitumumab

scientific article published on 01 April 2021

Design and Validation of the GI-NEC Score to Prognosticate Overall Survival in Patients With High-Grade Gastrointestinal Neuroendocrine Carcinomas.

scientific article published on 27 January 2017

Dynamic molecular analysis and clinical correlates of tumor evolution within a phase II trial of panitumumab-based therapy in metastatic colorectal cancer.

scientific article published on 4 September 2017

ENETS Consensus Guidelines for High-Grade Gastroenteropancreatic Neuroendocrine Tumors and Neuroendocrine Carcinomas.

scientific article published on 05 January 2016

ENETS Consensus Guidelines for the Standards of Care in Neuroendocrine Neoplasms. Systemic Therapy 2: Chemotherapy

scientific article published on 05 April 2017

ENETS Consensus Guidelines for the Standards of Care in Neuroendocrine Neoplasms: Systemic Therapy - Biotherapy and Novel Targeted Agents

scientific article published on 29 March 2017

ENETS Consensus Guidelines for the Standards of Care in Neuroendocrine Tumors: Pre- and Perioperative Therapy in Patients with Neuroendocrine Tumors

scientific article published on 2 March 2017

Efficacy of trifluridine and tipiracil (TAS-102) versus placebo, with supportive care, in a randomized, controlled trial of patients with metastatic colorectal cancer from Spain: results of a subgroup analysis of the phase 3 RECOURSE trial

scientific article published on 21 July 2016

Epigenetic EGFR Gene Repression Confers Sensitivity to Therapeutic BRAFV600E Blockade in Colon Neuroendocrine Carcinomas

scientific article published on 31 October 2019

Erratum to: Equity, barriers and cancer disparities: study of the Spanish Society of Medical Oncology on the access to oncologic drugs in the Spanish Regions.

scientific article

Exposure-response relationship of ramucirumab in patients with advanced second-line colorectal cancer: exploratory analysis of the RAISE trial

scientific article

Expression of EGFR, HER-2/neu and KIT in germ cell tumours.

scientific article published in June 2010

Favorable prognosis after late relapse of Hodgkin's disease

scientific article published on 01 August 1998

Figitumumab in patients with refractory metastatic colorectal cancer previously treated with standard therapies: a nonrandomized, open-label, phase II trial

scientific article published on February 2014

GATA4 loss in the septum transversum mesenchyme promotes liver fibrosis in mice

scientific article published on 29 April 2014

Gastroenteropancreatic neuroendocrine tumors: current perspectives and future challenges

scientific article published in March 2014

Gene expression profile predictive of response to chemotherapy in metastatic colorectal cancer.

scientific article published on March 2015

Granulocyte colony-stimulating factor in the treatment of high-risk febrile neutropenia: a multicenter randomized trial.

scientific article

Guidelines for biomarker testing in colorectal carcinoma (CRC): a national consensus of the Spanish Society of Pathology (SEAP) and the Spanish Society of Medical Oncology (SEOM).

scientific article

Health-related quality of life in well-differentiated metastatic gastroenteropancreatic neuroendocrine tumors.

scientific article published on 6 August 2015

High-dose cyclophosphamide + carboplatin and interleukin-2 (IL-2) activated autologous stem cell transplantation followed by maintenance IL-2 therapy in metastatic breast carcinoma - a phase II study

scientific article published on 01 January 2000

Identification of oxidative stress related proteins as biomarkers for lung cancer and chronic obstructive pulmonary disease in bronchoalveolar lavage.

scientific article

Identification of proteomic signatures associated with lung cancer and COPD.

scientific article

Imaging approaches to assess the therapeutic response of gastroenteropancreatic neuroendocrine tumors (GEP-NETs): current perspectives and future trends of an exciting field in development

scientific article

Immunohistochemical assessment of Pax8 expression during pancreatic islet development and in human neuroendocrine tumors

scientific article

Incidence, patterns of care and prognostic factors for outcome of gastroenteropancreatic neuroendocrine tumors (GEP-NETs): results from the National Cancer Registry of Spain (RGETNE).

scientific article published on 05 February 2010

Inhibiting PI3K as a therapeutic strategy against cancer

scientific article published on September 2009

Inhibition of HSP90 molecular chaperones: moving into the clinic

scientific article

Is regorafenib providing clinically meaningful benefits to pretreated patients with metastatic colorectal cancer?

scientific article published on April 2016

Liquid biopsy detects early molecular response and predicts benefit to first-line chemotherapy plus cetuximab in metastatic colorectal cancer: PLATFORM-B study

scientific article published in 2022

Management of controversial gastroenteropancreatic neuroendocrine tumour clinical situations with somatostatin analogues: results of a Delphi questionnaire panel from the NETPraxis program

scientific article

MiR-107 and miR-99a-3p predict chemotherapy response in patients with advanced colorectal cancer

scientific article

MicroRNA clusters: dysregulation in lung adenocarcinoma and COPD.

scientific article published on 17 April 2014

MicroRNA-dependent regulation of transcription in non-small cell lung cancer

scientific article

Molecular biology of neuroendocrine tumors: from pathways to biomarkers and targets

scientific article published on March 2014

Neuroendocrine Tumor Heterogeneity Adds Uncertainty to the World Health Organization 2010 Classification: Real-World Data from the Spanish Tumor Registry (R-GETNE).

scientific article published on 12 January 2018

New targeted agents in gastroenteropancreatic neuroendocrine tumors ⬇️

scientific article published on May 15, 2012

Open-label, multicentre expansion cohort to evaluate imgatuzumab in pre-treated patients with KRAS-mutant advanced colorectal carcinoma

scientific article published on 18 November 2013

Optimization of RAS/BRAF Mutational Analysis Confirms Improvement in Patient Selection for Clinical Benefit to Anti-EGFR Treatment in Metastatic Colorectal Cancer.

scientific article

Optimizing Somatostatin Analog Use in Well or Moderately Differentiated Gastroenteropancreatic Neuroendocrine Tumors.

scientific article published on 18 September 2017

Outpatient therapy with oral ofloxacin for patients with low risk neutropenia and fever: a prospective, randomized clinical trial.

scientific article

Oxidized lipids in the metabolic profiling of neuroendocrine tumors - Analytical challenges and biological implications

scientific article published on 28 May 2020

PD-012Analysis of patients ≥75 years in the open-label phase 3b CONSIGN trial of regorafenib in previously treated metastatic colorectal cancer (mCRC).

scientific article published on 21 June 2016

PD-025RECOURSE trial: impact of adverse events on quality of life and duration of TAS-102 (trifluridine and tipiracil) treatment.

scientific article published on 21 June 2016

PD-029Baseline carcinoembryonic antigen (CEA) as a predictive factor of ramucirumab efficacy in RAISE, a second-line metastatic colorectal carcinoma (mCRC) phase 3 trial.

scientific article published on 21 June 2016

PDGFRα/β and VEGFR2 polymorphisms in colorectal cancer: incidence and implications in clinical outcome

scientific article

Patient selection in high-dose chemotherapy trials: relevance in high-risk breast cancer ⬇️

scientific article published on October 1, 1997

Pax8 Detection in Well-Differentiated Pancreatic Endocrine Tumors

scientific article published on 01 December 2011

Pazopanib in pretreated advanced neuroendocrine tumors: a phase II, open-label trial of the Spanish Task Force Group for Neuroendocrine Tumors (GETNE).

scientific article published on 10 June 2015

Phase 1 study of cetuximab in combination with 5-fluorouracil, cisplatin, and radiotherapy in patients with locally advanced anal canal carcinoma

article published in 2013

Phase 1 study of intravenous administration of the chimeric adenovirus enadenotucirev in patients undergoing primary tumor resection.

scientific article published on 19 September 2017

Phase I clinical trial of recombinant human endostatin administered as a short intravenous infusion repeated daily.

scientific article published in September 2002

Phase I/II study of gefitinib and capecitabine in patients with colorectal cancer.

scientific article published in January 2008

Phase II Study of BEZ235 versus Everolimus in Patients with Mammalian Target of Rapamycin Inhibitor-Naïve Advanced Pancreatic Neuroendocrine Tumors

scientific article

Phase II and pharmacokinetic study of ecteinascidin 743 in patients with progressive sarcomas of soft tissues refractory to chemotherapy.

scientific article

Phase II study of trastuzumab and cisplatin as first-line therapy in patients with HER2-positive advanced gastric or gastroesophageal junction cancer

scientific article published on 01 March 2011

Phase II trial of cisplatin and gemcitabine in advanced squamous-cell carcinoma of the head and neck.

scientific article

Plasma pharmacokinetics and bioavailability of 1-(2-chloroethyl)-3-sarcosinamide-1-nitrosourea after intravenous and oral administration to mice and dogs.

scientific article

Primary cisplatin, methotrexate and vinblastine chemotherapy with selective bladder preservation for muscle invasive carcinoma of the bladder: long-term followup of a prospective study

scientific article published on 01 June 2002

Prognostic factors and long-term outcome of pancreatic neuroendocrine neoplasms: Ki-67 index shows a greater impact on survival than disease stage. The large experience of the Spanish National Tumor Registry (RGETNE).

scientific article

Prognostic relevance of Src activation in stage II-III colon cancer

scientific article published on 7 June 2017

Prognostic relevance of estrogen receptor-α Ser167 phosphorylation in stage II-III colon cancer patients.

scientific article published on 2 September 2014

Prognostic value of KIT expression in small cell lung cancer

scientific article published on 08 April 2007

Proxies of quality of life in metastatic colorectal cancer: analyses in the RECOURSE trial

scientific article published on 23 November 2017

Ramucirumab Clinical Development: an Emerging Role in Gastrointestinal Tumors

scientific article published on 18 February 2016

Randomized Phase II Trial of Parsatuzumab (Anti-EGFL7) or Placebo in Combination with FOLFOX and Bevacizumab for First-Line Metastatic Colorectal Cancer.

scientific article published on October 2017

Randomized trial of TAS-102 for refractory metastatic colorectal cancer

scientific article published on May 2015

Recent Therapeutic Advances and Change in Treatment Paradigm of Patients with Merkel Cell Carcinoma

scientific article published on 08 April 2019

Recommendations and expert opinion on the adjuvant treatment of colon cancer in Spain ⬇️

scientific article published on November 1, 2011

SEOM clinical guidelines for diagnosis and treatment of metastatic colorectal cancer 2015.

scientific article

SEOM clinical guidelines for the diagnosis and treatment of gastric adenocarcinoma

scientific article published in July 2012

SEOM clinical guidelines for the diagnosis and treatment of gastroenteropancreatic and bronchial neuroendocrine neoplasms (NENs) (2018)

scientific article published on 07 December 2018

SEOM clinical guidelines for the diagnosis and treatment of gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) 2014

scientific article

SEOM clinical guidelines for the diagnosis and treatment of gastroenteropancreatic neuroendocrine tumours (GEP NETS)

scientific article published on 01 August 2011

SEOM clinical guidelines for the treatment of advanced colorectal cancer

scientific article published in November 2010

SEOM clinical guidelines for the treatment of advanced colorectal cancer 2013.

scientific article published on 30 July 2013

SEOM/SERAM consensus statement on radiological diagnosis, response assessment and follow-up in colorectal cancer

scientific article

Safety and Activity of the First-in-Class Sym004 Anti-EGFR Antibody Mixture in Patients with Refractory Colorectal Cancer.

scientific article published on 11 May 2015

Safety and efficacy of nintedanib for the treatment of metastatic colorectal cancer

scientific article

Sorafenib and bevacizumab combination targeted therapy in advanced neuroendocrine tumour: a phase II study of Spanish Neuroendocrine Tumour Group (GETNE0801)

scientific article published on 05 September 2013

Sorafenib in Combination with Oxaliplatin, Leucovorin, and Fluorouracil (Modified FOLFOX6) as First-line Treatment of Metastatic Colorectal Cancer: The RESPECT Trial

scientific article published on 26 March 2013

Spanish Society of Medical Oncology consensus for the use of haematopoietic colony-stimulating factors in cancer patients.

scientific article published on July 2009

Spinophilin loss correlates with poor patient prognosis in advanced stages of colon carcinoma.

scientific article published on 31 May 2013

Subgroup analysis in RAISE: a randomized, double-blind phase III study of irinotecan, folinic acid, and 5-fluorouracil (FOLFIRI) plus ramucirumab or placebo in patients with metastatic colorectal carcinoma progression

scientific article published on 29 August 2016

Sunitinib and Evofosfamide (TH-302) in Systemic Treatment-Naïve Patients with Grade 1/2 Metastatic Pancreatic Neuroendocrine Tumors: The GETNE-1408 Trial

scientific article published on 14 July 2021

Systemic chemotherapy in the management of malignant peritoneal mesothelioma.

scientific article

Systemic therapeutic strategies for GEP-NETS: what can we expect in the future?

scientific article published on March 2014

Targeting tyrosine kinase receptors in hepatocellular carcinoma.

scientific article published on March 2013

Telotristat ethyl in carcinoid syndrome: safety and efficacy in the TELECAST phase 3 trial

scientific article published on 12 January 2018

The Antiproliferative Role of Lanreotide in Controlling Growth of Neuroendocrine Tumors: A Systematic Review

scientific article published on 20 February 2017

The European Medicines Agency review of Tegafur/Gimeracil/Oteracil (Teysuno™) for the treatment of advanced gastric cancer when given in combination with cisplatin: summary of the Scientific Assessment of the Committee for medicinal products [...]

scientific article

The European medicines agency review of abiraterone for the treatment of metastatic castration-resistant prostate cancer in adult men after docetaxel chemotherapy and in chemotherapy-naive disease: summary of the scientific assessment of the committ

scientific article

The safety and efficacy of ramucirumab for the treatment of metastatic colorectal cancer.

scientific article published on 4 May 2016

Therapy innovations: tyrosine kinase inhibitors for the treatment of pancreatic neuroendocrine tumors.

scientific article published on March 2011

Translational research in neuroendocrine tumors: pitfalls and opportunities

scientific article published on 19 September 2016

Updated guidelines for biomarker testing in colorectal carcinoma: a national consensus of the Spanish Society of Pathology and the Spanish Society of Medical Oncology

scientific article

Well-Differentiated Grade 2, Type 3 Gastrointestinal Neuroendocrine Tumour with Bilateral Metastatic Ovarian Involvement: Report of an Unusual Case.

scientific article published on January 2016

Paulina is supported by:

About Paulina

Help