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List of works by Eva Szegezdi

An added dimension to tumour TRAIL sensitivity

scientific article

An unfractionated fucoidan from Ascophyllum nodosum: extraction, characterization, and apoptotic effects in vitro.

scientific article published on 29 August 2011

Apoptosis-linked in vivo regulation of the tissue transglutaminase gene promoter

scientific article published on 01 December 2000

Aspartic Aminopeptidase Is a Novel Biomarker of Aggressive Chronic Lymphocytic Leukemia

scientific article published on 12 July 2020

BCL-2 modulates the unfolded protein response by enhancing splicing of X-box binding protein-1.

scientific article published on 25 August 2015

Bcl-2 family on guard at the ER.

scientific article published on 11 March 2009

CD95-mediated alteration in Hsp70 levels is dependent on protein stabilization.

scientific article

Caspase-12 and ER-stress-mediated apoptosis: the story so far.

scientific article

Cell death in HIV pathogenesis and its modulation by retinoids.

scientific article

Cell-cell interactome of the hematopoietic niche and its changes in acute myeloid leukemia

scientific article published in 2023

Clearance of apoptotic thymocytes is decreased by inhibitors of eicosanoid synthesis

scientific article published on 01 July 1999

Co-acting gene networks predict TRAIL responsiveness of tumour cells with high accuracy.

scientific article

Correlation between potassium channel expression and sensitivity to drug-induced cell death in tumor cell lines

scientific article published on January 2014

Cytokine-induced beta-cell apoptosis is NO-dependent, mitochondria-mediated and inhibited by BCL-XL.

scientific article published on 10 December 2007

DR4-selective tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) variants obtained by structure-based design

scientific article

Decorated macrocycles via ring-closing double-reductive amination. identification of an apoptosis inducer of leukemic cells that at least partially antagonizes a 5-HT2 receptor.

scientific article published on 16 March 2015

Decoy receptors block TRAIL sensitivity at a supracellular level: the role of stromal cells in controlling tumour TRAIL sensitivity.

scientific article published on 8 June 2015

Designed tumor necrosis factor-related apoptosis-inducing ligand variants initiating apoptosis exclusively via the DR5 receptor

scholarly article

Dexamethasone inhibits apoptosis in C6 glioma cells through increased expression of Bcl-XL.

scientific article published on July 2006

Differential activation of JNK1 isoforms by TRAIL receptors modulate apoptosis of colon cancer cell lines.

scientific article published on 07 April 2009

ER stress contributes to ischemia-induced cardiomyocyte apoptosis

scientific journal article

Early growth response-1 is a regulator of DR5-induced apoptosis in colon cancer cells.

scientific article

Enhancement of antitumor properties of rhTRAIL by affinity increase toward its death receptors.

scientific article

Generation of Tumour-stroma Minispheroids for Drug Efficacy Testing

publication published on 05 January 2017

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

Guiding the Killer and Bringing in Accomplices: Bispecific Antibody Treatment for Malignant Melanoma

scientific article published in February 2016

Hsp27 inhibits 6-hydroxydopamine-induced cytochrome c release and apoptosis in PC12 cells

scientific article published in February 2005

Hypoxia and ischemia induce nuclear condensation and caspase activation in cardiomyocytes.

scientific article published on December 2003

Identification of an inhibitor of caspase activation from heart extracts; ATP blocks apoptosome formation

scientific article published in March 2007

Is there a role for nuclear factor kappaB in tumor necrosis factor-related apoptosis-inducing ligand resistance?

scientific article published on August 2009

Kinetics in Signal Transduction Pathways Involving Promiscuous Oligomerizing Receptors Can Be Determined by Receptor Specificity: Apoptosis Induction by TRAIL ⬇️

scientific article published on January 2, 2012

Ligation of retinoic acid receptor alpha regulates negative selection of thymocytes by inhibiting both DNA binding of nur77 and synthesis of bim.

scientific article published in April 2003

Mechanisms of ER Stress-Mediated Mitochondrial Membrane Permeabilization

scientific article

Metabolic flexibility permits mesenchymal stem cell survival in an ischemic environment.

scientific article

N-glycosylation of mouse TRAIL-R and human TRAIL-R1 enhances TRAIL-induced death

scientific article published on 10 February 2017

NOXA contributes to the sensitivity of PERK-deficient cells to ER stress.

scientific article

Nerve growth factor blocks thapsigargin-induced apoptosis at the level of the mitochondrion via regulation of Bim

scientific journal article

Rapid and efficient cancer cell killing mediated by high-affinity death receptor homotrimerizing TRAIL variants.

scientific article

Recreating complex pathophysiologies in vitro with extracellular matrix surrogates for anticancer therapeutics screening.

scientific article

Recreating the Bone Marrow Microenvironment to Model Leukemic Stem Cell Quiescence

scientific article published on 13 September 2021

Repression of Mcl-1 expression by the CDC7/CDK9 inhibitor PHA-767491 overcomes bone marrow stroma-mediated drug resistance in AML

scientific article published in Scientific Reports

Resistance to TRAIL in non-transformed cells is due to multiple redundant pathways ⬇️

scientific article published on 04 July 2013

Retinoid receptor-activating ligands are produced within the mouse thymus during postnatal development.

scientific article

Stem cells are resistant to TRAIL receptor-mediated apoptosis.

scientific article published in November 2009

Structural determinants of DISC function: New insights into death receptor-mediated apoptosis signalling ⬇️

scientific article published on July 8, 2013

Synthetic constrained peptide selectively binds and antagonizes death receptor 5.

scientific article

TRAIL receptor gene editing unveils TRAIL-R1 as a master player of apoptosis induced by TRAIL and ER stress

scientific article published on 27 December 2016

TRAIL receptor signalling and modulation: Are we on the right TRAIL?

scientific article

TRAIL sensitisation by arsenic trioxide is caspase-8 dependent and involves modulation of death receptor components and Akt.

scientific article

Targeting AML through DR4 with a novel variant of rhTRAIL

scientific article

Targeting TRAIL towards the clinic.

scientific article published on December 2011

The BH3-mimetic ABT-737 effectively kills acute myeloid leukemia initiating cells

scientific article

The Janus Face of Death Receptor Signaling during Tumor Immunoediting

scientific article

The Proteasome Inhibitor Bortezomib Sensitizes AML with Myelomonocytic Differentiation to TRAIL Mediated Apoptosis.

scientific article published on 15 March 2011

The mitochondrial death pathway: a promising therapeutic target in diseases

scientific article published on 9 February 2009

The pyrrolo-1,5-benzoxazepine, PBOX-15, enhances TRAIL‑induced apoptosis by upregulation of DR5 and downregulation of core cell survival proteins in acute lymphoblastic leukaemia cells

scientific article published on 12 May 2016

Theranostic drug test incorporating the bone-marrow microenvironment can predict the clinical response of acute myeloid leukaemia to chemotherapy

scientific article published on 28 April 2020

Three-dimensional ex vivo co-culture models of the leukaemic bone marrow niche for functional drug testing

scientific article published on 26 April 2016

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