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List of works by Tricia Naicker

(1R,3S)-Methyl 2-benzyl-6,7-dimeth-oxy-1-phenyl-1,2,3,4-tetra-hydro-isoquinoline-3-carboxyl-ate.

scientific article

(1R,3S)-Methyl 6,7-dimeth-oxy-1-(4-meth-oxy-phen-yl)-1,2,3,4-tetra-hydro-isoquinoline-3-carboxyl-ate

scientific article

(1R,3S)-N-Benzhydryl-2-benzyl-6,7-dimeth-oxy-1-phenyl-1,2,3,4-tetra-hydro-isoquinoline-3-carbothio-amide

scientific article published on 25 November 2011

(1S,3S)-Methyl 2-benzyl-6,7-dimeth-oxy-1-phenyl-1,2,3,4-tetra-hydro-isoquinoline-3-carboxyl-ate.

scientific article

(1S,3S)-Methyl 6,7-dimeth-oxy-1-phenyl-1,2,3,4-tetra-hydro-isoquinoline-3-carboxyl-ate

scientific article

(3S)-2-Benzyl-3-carb-oxy-1,2,3,4-tetra-hydro-isoquinolinium chloride monohydrate.

scientific article

(S)-2-Benzyl-N-(2,6-diisopropyl-phen-yl)-1,2,3,4-tetra-hydro-isoquinoline-3-carboxamide.

scientific article

(S)-Benzyl 3-phenyl-carbamoyl-1,2,3,4-tetra-hydro-isoquinoline-2-carboxyl-ate.

scientific article published on 29 February 2012

(S)-Methyl 2-benzamido-3-(3,4-dimeth-oxy-phen-yl)propano-ate.

scientific article published on 21 December 2011

(S)-Methyl 3-(3,4-dimethoxyphenyl)-2-[2-(diphenylphosphanyl)benzamido]propanoate

scientific article published on November 12, 2011

6,7-Dimeth-oxy-3-meth-oxy-carbonyl-1-(2-meth-oxy-phen-yl)-3,4-dihydro-isoquinoline 2-oxide.

scientific article

A Synthesis of "Dual Warhead" β-Aryl Ethenesulfonyl Fluorides and One-Pot Reaction to β-Sultams.

scientific article

A novel and more efficient biosynthesis approach for human insulin production in Escherichia coli (E. coli)

scientific article published on 10 March 2020

An unexpected re-arrangement of the antibiotic carbapenem core to new 1,4-diazepin-5-one scaffolds

scholarly article in RSC Advances, vol. 8 no. 1, 2018

Applied Enantioselective Aminocatalysis: α-Heteroatom Functionalization Reactions on the Carbapenem (β-Lactam Antibiotic) Core

Asymmetric organocatalytic epoxidations: reactions, scope, mechanisms, and applications.

scientific article

Beyond classical reactivity patterns: shifting from 1,4- to 1,6-additions in regio- and enantioselective organocatalyzed vinylogous reactions of olefinic lactones with enals and 2,4-dienals

scientific article published on 16 May 2013

Brain penetration of ketamine: Intranasal delivery VS parenteral routes of administraion

scientific article published on 20 February 2019

Clofazimine protects against mycobacterium tuberculosis dissemination in the CNS following an aerosol challenge in a murine model.

scientific article

Concerted hydrolysis mechanism of HIV-1 natural substrate against subtypes B and C-SA PR: insight through molecular dynamics and hybrid QM/MM studies

scientific article published on 16 January 2020

Cu(OAc)2-Catalysed Oxidative Dual C-H/N-H Activation of Terminal Alkynes andN-Deprotected Sulfonimidamides: An Easy Access toN-Alkynylated Sulfonimidamides

article by Ganesh Chandra Nandi et al published 17 March 2015 in European Journal of Organic Chemistry

Development and validation of a liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for the quantification of tigecycline in rat brain tissues.

scientific article published on 17 September 2015

Enantioselective Organocatalyzed Transformations of β-Ketoesters.

scientific article

Enhanced brain penetration of pretomanid by intranasal administration of an oil-in-water nanoemulsion

scientific article published on 23 May 2018

Evidence for the presence of clofazimine and its distribution in the healthy mouse brain.

scientific article published on 25 July 2015

Exploring the concerted mechanistic pathway for HIV-1 PR-substrate revealed by umbrella sampling simulation

scientific article published on 19 October 2020

In vitro evaluation of metal chelators as potential metallo- β -lactamase inhibitors

scientific article published on 5 February 2016

Investigating time dependent brain distribution of nevirapine via mass spectrometric imaging

scientific article published on 04 November 2019

Kinetic and thermodynamic characterisation of HIV-protease inhibitors against E35D↑G↑S mutant in the South African HIV-1 subtype C protease

scientific article published on 01 December 2019

Lansoprazole-sulfide, pharmacokinetics of this promising anti-tuberculous agent.

scientific article

Lymphatic vascular endothelial hyaluronan receptor-1 immunoexpression in placenta of HIV infected pre-eclamptic women.

scientific article published on 18 July 2016

MALDI MSI and LC-MS/MS: Towards preclinical determination of the neurotoxic potential of fluoroquinolones.

scientific article published on 18 September 2015

Mass Spectrometry Imaging Demonstrates the Regional Brain Distribution Patterns of Three First-Line Antiretroviral Drugs

scientific article published on 05 December 2019

Mass spectrometric investigations into the brain delivery of abacavir, stavudine and didanosine in a rodent model

scientific article published on 29 August 2019

Methyl 1-cyclo-hexyl-6,7-dimeth-oxy-3,4-dihydro-isoquinoline-3-carboxyl-ate.

scientific article

Microwave-Assisted Synthesis of Guanidine Organocatalysts Bearing a Tetrahydroisoquinoline Framework and Their Evaluation in Michael Addition Reactions

article

Microwave-assisted synthesis of meso-carboxyalkyl-BODIPYs and an application to fluorescence imaging

scientific article published on 28 September 2020

N-Trifluoromethylthiolated Sulfonimidamides and Sulfoximines: Anti-microbial, Anti-mycobacterial, and Cytotoxic Activity

scientific article published on 11 September 2019

NOTA: a potent metallo-β-lactamase inhibitor.

scientific article published on 6 January 2015

Neuroprotective potential of Linezolid: a quantitative and distribution study via mass spectrometry.

scientific article published on 21 June 2016

Novel tetrahydroisoquinoline based organocatalysts for asymmetric Diels–Alder reactions: insight into the catalytic mode using ROESY NMR and DFT studies

On-Water Synthesis of Biaryl Sulfonyl Fluorides

scientific article published on 29 February 2016

Optically active diaryl tetrahydroisoquinoline derivatives

scientific article published on 08 February 2011

Optimized Procedure for Recovering HIV-1 Protease (C-SA) from Inclusion Bodies

article

Organocatalytic Mannich Reactions on a Carbapenem Core - Synthesis of Mannich Bases and Bicyclic Diazanonanes

Organocatalytic asymmetric remote aziridination of 2,4-dienals.

scientific article published in July 2013

Pd-catalyzed C–N coupling of vinylbromides and sulfonimidamides: a facile synthesis of N′-vinylsulfonimidamides

scholarly article in RSC Advances, vol. 5 no. 76, 2015

Post heroin dose tissue distribution of 6-monoacetylmorphine (6-MAM) with MALDI imaging

scientific article

Rapid and widespread distribution of doxycycline in rat brain: a mass spectrometric imaging study.

scientific article

Rilpivirine as a potential candidate for the treatment of HIV-associated neurocognitive disorders (HAND)

scientific article published on 22 April 2019

Small molecule distribution in rat lung: a comparison of various cryoprotectants as inflation media and their applicability to MSI.

scientific article published on 13 January 2016

Sulfonimidamide in medizinischer Chemie und Agrochemie

Sulfonimidamides in Medicinal and Agricultural Chemistry

scientific article published on 13 December 2016

Synthesis and Biological Evaluation of a Teixobactin Analogue.

scientific article published on 10 December 2015

Synthesis of novel 1,2,4-thiadiazinane 1,1-dioxides via three component SuFEx type reaction

scholarly article in RSC Advances, vol. 8 no. 65, 2018

Synthesis, in vitro evaluation, and 68 Ga-radiolabeling of CDP1 toward PET/CT imaging of bacterial infection.

scientific article published on 22 March 2017

Synthetic approaches to radiochemical probes for imaging of bacterial infections.

scientific article published on 29 March 2017

Tetrahydroisoquinoline-Based N-Oxides as Chiral Organocatalysts for the Asymmetric Allylation of Aldehydes

The Driving Force for the Acylation of β-Lactam Antibiotics by L,D-Transpeptidase 2: Quantum Mechanics/Molecular Mechanics (QM/MM) Study

scientific article published on 10 April 2019

The Screening of Nails for Selected Essential and Toxic Elements in Normotensive and Pre-Eclamptic Women

scientific article published on 02 August 2018

Time-dependent regional brain distribution of methadone and naltrexone in the treatment of opioid addiction.

scientific article published on 14 February 2018

Tissue distribution of pretomanid in rat brain via mass spectrometry imaging

scientific article published on 24 July 2015

Towards a stereoselective synthesis of α,α-disubstituted proline analogues

Zidovudine and Lamivudine as Potential Agents to Combat HIV-Associated Neurocognitive Disorder

scientific article published on 01 October 2019

l-Proline organocatalyzed Michael synthesis of monobactam and carbapenem β-lactam cores

{(1R,3S)-2-Benzyl-6,7-dimeth-oxy-1-phenyl-1,2,3,4-tetra-hydro-isoquinolin-3-yl}diphenyl-methanol.

scientific article