List of works - Marie-Catherine Vozenin

A need for biology-driven personalized radiotherapy in breast cancer

scientific article published on 27 September 2017

Abdominal irradiation increases inflammatory cytokine expression and activates NF-kappaB in rat ileal muscularis layer

scientific article published on 01 September 2003

Altered proliferation and differentiation of human epidermis in cases of skin fibrosis after radiotherapy

scientific article published on 01 June 2002

Antifibrotic, Antioxidant, and Immunomodulatory Effects of Mesenchymal Stem Cells in HOCl-Induced Systemic Sclerosis.

scientific article published in April 2016

Biological Benefits of Ultra-high Dose Rate FLASH Radiotherapy: Sleeping Beauty Awoken

scientific article published on 19 April 2019

Bioluminescent orthotopic mouse models of human localized non-small cell lung cancer: feasibility and identification of circulating tumour cells

scientific article

CSF1R inhibition prevents radiation pulmonary fibrosis by depletion of interstitial macrophages

scientific article published on 01 March 2018

Cancer stem cells: a new target for lung cancer treatment

scientific article published on 12 June 2011

Cardiac Radionuclide Imaging in Rodents: A Review of Methods, Results, and Factors at Play.

scientific article published on 29 March 2017

Cellular Composition and Contribution of Tertiary Lymphoid Structures to Tumor Immune Infiltration and Modulation by Radiation Therapy

article

Cidofovir administered with radiation displays an antiangiogenic effect mediated by E6 inhibition and subsequent TP53-dependent VEGF repression in HPV18+ cell lines.

scientific article published on October 2006

Clinical translation of FLASH radiotherapy: Why and how?

scientific article published on 25 June 2019

Coactivation of AP-1 activity and TGF-beta1 gene expression in the stress response of normal skin cells to ionizing radiation

scientific article published on 01 August 1997

Collapse of skin antioxidant status during the subacute period of cutaneous radiation syndrome: a case report

scientific article published on 01 January 2007

Comparative gene expression profiling in three primary human cell lines after treatment with a novel inhibitor of Rho kinase or atorvastatin

scientific article

Comparison between Stromal Vascular Fraction and Adipose Mesenchymal Stem Cells in Remodeling Hypertrophic Scars

scientific article

Cytotoxic effect of lapatinib is restricted to human papillomavirus-positive head and neck squamous cell carcinoma cell lines

scientific article

Differential effect triggered by a heparan mimetic of the RGTA family preventing oral mucositis without tumor protection.

scientific article

Differential expression of the Hs Kin17 protein during differentiation of in vitro reconstructed human skin ⬇️

scientific article published on July 1, 1997

Dosimetric and preparation procedures for irradiating biological models with pulsed electron beam at ultra-high dose-rate

scientific article published on 04 June 2019

Durable and controlled depletion of neutrophils in mice

scientific article published on 02 June 2020

Enhanced local control by radiation boost in breast cancer: back side of the coin?

scientific article

Enhanced sensitivity to low dose irradiation of ApoE-/- mice mediated by early pro-inflammatory profile and delayed activation of the TGFβ1 cascade involved in fibrogenesis

scientific article

Epac contributes to cardiac hypertrophy and amyloidosis induced by radiotherapy but not fibrosis

scientific article published on 07 April 2014

Expanding the therapeutic index of radiation therapy by normal tissue protection.

scientific article published on 25 April 2018

Experimental Drainage Device to Reduce Lymphoedema in a Rat Model

scientific article published on 25 May 2018

Expression and activation of MMP -2, -3, -9, -14 are induced in rat colon after abdominal X-irradiation.

scientific article

Expression of matrix metalloproteinases and tissue inhibitor metalloproteinases increases in X-irradiated rat ileum despite the disappearance of CD8a T cells.

scientific article published on October 2005

FLASH radiotherapy International Workshop

scientific article published on 21 August 2019

Fc-receptor-mediated intracellular delivery of Cu/Zn-superoxide dismutase (SOD1) protects against redox-induced apoptosis through a nitric oxide dependent mechanism.

scientific article

Fibrogenic signals in patients with radiation enteritis are associated with increased connective tissue growth factor expression

scientific article published on 01 June 2003

Fibrosis Development in HOCl-Induced Systemic Sclerosis: A Multistage Process Hampered by Mesenchymal Stem Cells

article

Gene expression profile in human late radiation enteritis obtained by high-density cDNA array hybridization.

scientific article published in March 2004

Glucagon-like peptide-2 improves both acute and late experimental radiation enteritis in the rat.

scientific article published in December 2007

High dose-per-pulse electron beam dosimetry - A model to correct for the ion recombination in the Advanced Markus ionization chamber

scientific article published on 17 January 2017

High dose-per-pulse electron beam dosimetry: Commissioning of the Oriatron eRT6 prototype linear accelerator for preclinical use.

scientific article published on 5 December 2017

High dose-per-pulse electron beam dosimetry: Usability and dose-rate independence of EBT3 Gafchromic films

scientific article published on 26 December 2016

Histopathological and cellular studies of a case of cutaneous radiation syndrome after accidental chronic exposure to a cesium source

scientific article published on 01 September 1999

How could breast cancer molecular features contribute to locoregional treatment decision making?

scientific article published on 8 December 2016

Inhibition of Rho kinase modulates radiation induced fibrogenic phenotype in intestinal smooth muscle cells through alteration of the cytoskeleton and connective tissue growth factor expression

scientific article published on March 2005

Irradiation in a flash: Unique sparing of memory in mice after whole brain irradiation with dose rates above 100Gy/s

scientific article published on 22 May 2017

Isodose 20 Gy found as a threshold dose for radiation recall dermatitis

scientific article published on 11 April 2019

Long-term neurocognitive benefits of FLASH radiotherapy driven by reduced reactive oxygen species

scientific article published on 16 May 2019

Lung cancer stem cell: new insights on experimental models and preclinical data.

scientific article

Maintenance of radiation-induced intestinal fibrosis: cellular and molecular features

scientific article published on May 2007

MiR-210: A potential therapeutic target against radiation-induced enteropathy

scientific article published on 26 November 2013

Modulation of the Rho/ROCK pathway in heart and lung after thorax irradiation reveals targets to improve normal tissue toxicity.

scientific article

Molecular aspects of intestinal radiation-induced fibrosis.

scientific article published on April 2009

Neuroprotection of Radiosensitive Juvenile Mice by Ultra-High Dose Rate FLASH Irradiation

scientific article published on 24 June 2020

Normal tissues toxicities triggered by combined anti-angiogenic and radiation therapies: hurdles might be ahead

scientific article

Novel anti-metastatic action of cidofovir mediated by inhibition of E6/E7, CXCR4 and Rho/ROCK signaling in HPV tumor cells.

scientific article

Pharmacological strategies to spare normal tissues from radiation damage: useless or overlooked therapeutics? ⬇️

scientific article published on December 1, 2012

PrP(c) deficiency and dasatinib protect mouse intestines against radiation injury by inhibiting of c-Src.

scientific article published on 9 July 2016

Pravastatin Inhibits the Rho/CCN2/extracellular matrix cascade in human fibrosis explants and improves radiation-induced intestinal fibrosis in rats

scientific article published on 01 September 2007

Pravastatin Reverses Established Radiation-Induced Cutaneous and Subcutaneous Fibrosis in Patients With Head and Neck Cancer: Results of the Biology-Driven Phase 2 Clinical Trial Pravacur

scientific article published on 15 February 2019

Pravastatin limits endothelial activation after irradiation and decreases the resulting inflammatory and thrombotic responses.

scientific article published in May 2005

Promoter sequences involved in transforming growth factor beta1 gene induction in HaCaT keratinocytes after gamma irradiation.

scientific article published on March 2002

Radiation-induced enteropathy: molecular basis of pentoxifylline-vitamin E anti-fibrotic effect involved TGF-β1 cascade inhibition

scientific article published on 27 September 2012

Radiobiology: a multidisciplinary interface ⬇️

scientific article published on 01 August 2011

Radiosensitivity of human papillomavirus-related tumors: in regard to Gupta et al. (Int J Radiat Oncol Biol Phys 2009;74:928-933).

scientific article published in February 2011

Reirradiation of normal tissues: preclinical radiobiological data

scientific article

Rho/ROCK pathway as a molecular target for modulation of intestinal radiation-induced toxicity.

scientific article published on September 2007

Simultaneous irradiation of fibroblasts and carcinoma cells repress the secretion of soluble factors able to stimulate carcinoma cell migration

scientific article published on 30 January 2015

Specific signals involved in the long-term maintenance of radiation-induced fibrogenic differentiation: a role for CCN2 and low concentration of TGF-beta1

scientific article published on 09 April 2008

Striking regression of subcutaneous fibrosis induced by high doses of gamma rays using a combination of pentoxifylline and alpha-tocopherol: an experimental study

scientific article published on 01 March 1999

Synergy of Radiotherapy and a Cancer Vaccine for the Treatment of HPV-Associated Head and Neck Cancer

scientific article

TAT-RasGAP317-326 Enhances Radiosensitivity of Human Carcinoma Cell Lines In Vitro and In Vivo through Promotion of Delayed Mitotic Cell Death

scientific article published on 21 March 2017

TRIM33 deficiency in monocytes and macrophages impairs resolution of colonic inflammation

scientific article published on 24 May 2019

The Advantage of FLASH Radiotherapy Confirmed in Mini-pig and Cat-cancer Patients

scientific article published on 06 June 2018

The combination of the antiviral agent cidofovir and anti-EGFR antibody cetuximab exerts an antiproliferative effect on HPV-positive cervical cancer cell lines' in-vitro and in-vivo xenografts.

scientific article published on July 2013

The myofibroblast markers α-SM actin and β-actin are differentially expressed in 2 and 3-D culture models of fibrotic and normal skin.

scientific article published on January 1998

The radiosensitizing activity of the SMAC-mimetic, Debio 1143, is TNFα-mediated in head and neck squamous cell carcinoma.

scientific article

The radiotherapy FLASH to save healthy tissues

scientific article

Therapeutic management of intestinal fibrosis induced by radiation therapy: from molecular profiling to new intervention strategies et vice et versa

scientific article

Tissue toxicity induced by ionizing radiation to the normal intestine: understanding the pathophysiological mechanisms to improve the medical management.

scientific article published on June 2007

Treatment of a first patient with FLASH-radiotherapy

scientific article published on 11 July 2019

Ultrahigh dose-rate FLASH irradiation increases the differential response between normal and tumor tissue in mice.

scientific article published in July 2014

Unravelling the biology of human papillomavirus (HPV) related tumours to enhance their radiosensitivity.

scientific article published on 22 April 2010

What have we learned from human papillomavirus-positive tumors? Trying to connect data about biomarkers among human papillomavirus-related squamous cell carcinomas.

scientific article published on 10 May 2010

X-rays can trigger the FLASH effect: Ultra-high dose-rate synchrotron light source prevents normal brain injury after whole brain irradiation in mice

scientific article published on 31 August 2018

[Effect of ionizing radiation on transforming growth factor-beta expression]

scientific article published on 01 November 1998

[Hopes of high dose-rate radiotherapy]

scientific article published on 07 March 2017

[How to model the events in cutaneous fibrosis?]

scientific article published on 01 February 2006

[Management of refractory ventricular tachycardia using stereotactic body radiotherapy]

scientific article published on 01 May 2019

[Pharmacological modulation of late radio-induced side effects]

scientific article published on 18 May 2011

[Radiation-induced superficial fibrosis and TGF-alpha 1]

scientific article published on 01 September 2000

[Ultrahigh dose-rate, "flash" irradiation minimizes the side-effects of radiotherapy]

scientific article published on 12 August 2015

List of works by Marie-Catherine Vozenin

A need for biology-driven personalized radiotherapy in breast cancer

Abdominal irradiation increases inflammatory cytokine expression and activates NF-kappaB in rat ileal muscularis layer

Altered proliferation and differentiation of human epidermis in cases of skin fibrosis after radiotherapy

Antifibrotic, Antioxidant, and Immunomodulatory Effects of Mesenchymal Stem Cells in HOCl-Induced Systemic Sclerosis.

Biological Benefits of Ultra-high Dose Rate FLASH Radiotherapy: Sleeping Beauty Awoken

Bioluminescent orthotopic mouse models of human localized non-small cell lung cancer: feasibility and identification of circulating tumour cells

CSF1R inhibition prevents radiation pulmonary fibrosis by depletion of interstitial macrophages

Cancer stem cells: a new target for lung cancer treatment

Cardiac Radionuclide Imaging in Rodents: A Review of Methods, Results, and Factors at Play.

Cellular Composition and Contribution of Tertiary Lymphoid Structures to Tumor Immune Infiltration and Modulation by Radiation Therapy

Cidofovir administered with radiation displays an antiangiogenic effect mediated by E6 inhibition and subsequent TP53-dependent VEGF repression in HPV18+ cell lines.

Clinical translation of FLASH radiotherapy: Why and how?

Coactivation of AP-1 activity and TGF-beta1 gene expression in the stress response of normal skin cells to ionizing radiation

Collapse of skin antioxidant status during the subacute period of cutaneous radiation syndrome: a case report

Comparative gene expression profiling in three primary human cell lines after treatment with a novel inhibitor of Rho kinase or atorvastatin

Comparison between Stromal Vascular Fraction and Adipose Mesenchymal Stem Cells in Remodeling Hypertrophic Scars

Cytotoxic effect of lapatinib is restricted to human papillomavirus-positive head and neck squamous cell carcinoma cell lines

Differential effect triggered by a heparan mimetic of the RGTA family preventing oral mucositis without tumor protection.

Differential expression of the Hs Kin17 protein during differentiation of in vitro reconstructed human skin ⬇️

Dosimetric and preparation procedures for irradiating biological models with pulsed electron beam at ultra-high dose-rate

Durable and controlled depletion of neutrophils in mice

Enhanced local control by radiation boost in breast cancer: back side of the coin?

Enhanced sensitivity to low dose irradiation of ApoE-/- mice mediated by early pro-inflammatory profile and delayed activation of the TGFβ1 cascade involved in fibrogenesis

Epac contributes to cardiac hypertrophy and amyloidosis induced by radiotherapy but not fibrosis

Expanding the therapeutic index of radiation therapy by normal tissue protection.

Experimental Drainage Device to Reduce Lymphoedema in a Rat Model

Expression and activation of MMP -2, -3, -9, -14 are induced in rat colon after abdominal X-irradiation.

Expression of matrix metalloproteinases and tissue inhibitor metalloproteinases increases in X-irradiated rat ileum despite the disappearance of CD8a T cells.

FLASH radiotherapy International Workshop

Fc-receptor-mediated intracellular delivery of Cu/Zn-superoxide dismutase (SOD1) protects against redox-induced apoptosis through a nitric oxide dependent mechanism.

Fibrogenic signals in patients with radiation enteritis are associated with increased connective tissue growth factor expression

Fibrosis Development in HOCl-Induced Systemic Sclerosis: A Multistage Process Hampered by Mesenchymal Stem Cells

Gene expression profile in human late radiation enteritis obtained by high-density cDNA array hybridization.

Glucagon-like peptide-2 improves both acute and late experimental radiation enteritis in the rat.

High dose-per-pulse electron beam dosimetry - A model to correct for the ion recombination in the Advanced Markus ionization chamber

High dose-per-pulse electron beam dosimetry: Commissioning of the Oriatron eRT6 prototype linear accelerator for preclinical use.

High dose-per-pulse electron beam dosimetry: Usability and dose-rate independence of EBT3 Gafchromic films

Histopathological and cellular studies of a case of cutaneous radiation syndrome after accidental chronic exposure to a cesium source

How could breast cancer molecular features contribute to locoregional treatment decision making?

Inhibition of Rho kinase modulates radiation induced fibrogenic phenotype in intestinal smooth muscle cells through alteration of the cytoskeleton and connective tissue growth factor expression

Irradiation in a flash: Unique sparing of memory in mice after whole brain irradiation with dose rates above 100Gy/s

Isodose 20 Gy found as a threshold dose for radiation recall dermatitis

Long-term neurocognitive benefits of FLASH radiotherapy driven by reduced reactive oxygen species

Lung cancer stem cell: new insights on experimental models and preclinical data.

Maintenance of radiation-induced intestinal fibrosis: cellular and molecular features

MiR-210: A potential therapeutic target against radiation-induced enteropathy

Modulation of the Rho/ROCK pathway in heart and lung after thorax irradiation reveals targets to improve normal tissue toxicity.

Molecular aspects of intestinal radiation-induced fibrosis.

Neuroprotection of Radiosensitive Juvenile Mice by Ultra-High Dose Rate FLASH Irradiation

Normal tissues toxicities triggered by combined anti-angiogenic and radiation therapies: hurdles might be ahead

Novel anti-metastatic action of cidofovir mediated by inhibition of E6/E7, CXCR4 and Rho/ROCK signaling in HPV tumor cells.

Pharmacological strategies to spare normal tissues from radiation damage: useless or overlooked therapeutics? ⬇️

PrP(c) deficiency and dasatinib protect mouse intestines against radiation injury by inhibiting of c-Src.

Pravastatin Inhibits the Rho/CCN2/extracellular matrix cascade in human fibrosis explants and improves radiation-induced intestinal fibrosis in rats

Pravastatin Reverses Established Radiation-Induced Cutaneous and Subcutaneous Fibrosis in Patients With Head and Neck Cancer: Results of the Biology-Driven Phase 2 Clinical Trial Pravacur

Pravastatin limits endothelial activation after irradiation and decreases the resulting inflammatory and thrombotic responses.

Promoter sequences involved in transforming growth factor beta1 gene induction in HaCaT keratinocytes after gamma irradiation.

Radiation-induced enteropathy: molecular basis of pentoxifylline-vitamin E anti-fibrotic effect involved TGF-β1 cascade inhibition

Radiobiology: a multidisciplinary interface ⬇️

Radiosensitivity of human papillomavirus-related tumors: in regard to Gupta et al. (Int J Radiat Oncol Biol Phys 2009;74:928-933).

Reirradiation of normal tissues: preclinical radiobiological data

Rho/ROCK pathway as a molecular target for modulation of intestinal radiation-induced toxicity.

Simultaneous irradiation of fibroblasts and carcinoma cells repress the secretion of soluble factors able to stimulate carcinoma cell migration

Specific signals involved in the long-term maintenance of radiation-induced fibrogenic differentiation: a role for CCN2 and low concentration of TGF-beta1

Striking regression of subcutaneous fibrosis induced by high doses of gamma rays using a combination of pentoxifylline and alpha-tocopherol: an experimental study

Synergy of Radiotherapy and a Cancer Vaccine for the Treatment of HPV-Associated Head and Neck Cancer

TAT-RasGAP317-326 Enhances Radiosensitivity of Human Carcinoma Cell Lines In Vitro and In Vivo through Promotion of Delayed Mitotic Cell Death

TRIM33 deficiency in monocytes and macrophages impairs resolution of colonic inflammation

The Advantage of FLASH Radiotherapy Confirmed in Mini-pig and Cat-cancer Patients

The combination of the antiviral agent cidofovir and anti-EGFR antibody cetuximab exerts an antiproliferative effect on HPV-positive cervical cancer cell lines' in-vitro and in-vivo xenografts.

The myofibroblast markers α-SM actin and β-actin are differentially expressed in 2 and 3-D culture models of fibrotic and normal skin.

The radiosensitizing activity of the SMAC-mimetic, Debio 1143, is TNFα-mediated in head and neck squamous cell carcinoma.

The radiotherapy FLASH to save healthy tissues

Therapeutic management of intestinal fibrosis induced by radiation therapy: from molecular profiling to new intervention strategies et vice et versa

Tissue toxicity induced by ionizing radiation to the normal intestine: understanding the pathophysiological mechanisms to improve the medical management.

Treatment of a first patient with FLASH-radiotherapy

Ultrahigh dose-rate FLASH irradiation increases the differential response between normal and tumor tissue in mice.

Unravelling the biology of human papillomavirus (HPV) related tumours to enhance their radiosensitivity.

What have we learned from human papillomavirus-positive tumors? Trying to connect data about biomarkers among human papillomavirus-related squamous cell carcinomas.

Isodose 20 Gy found as a threshold dose for radiation recall dermatitis