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List of works by Erik Sjögren

A Model-Based Approach To Assessing the Importance of Intracellular Binding Sites in Doxorubicin Disposition

scientific article

A miniaturized in vitro release method for investigating drug-release mechanisms.

scientific article published on 2 April 2015

Assessment of Free Drug Concentration in Cyclodextrin Formulations Is Essential to Determine Drug Potency in Functional In Vitro Assays.

scientific article published on 15 July 2016

Clinical testing of three novel transient receptor potential cation channel subfamily V member 1 antagonists in a pharmacodynamic intradermal capsaicin model

scientific article published on 5 March 2018

Combining in vitro and in silico methods for better prediction of surfactant effects on the absorption of poorly water soluble drugs-a fenofibrate case example

scientific article published on 2 July 2014

Computational fluid dynamics (CFD) studies of a miniaturized dissolution system.

scientific article published on 9 February 2017

Concomitant intake of alcohol may increase the absorption of poorly soluble drugs.

scientific article published on 31 October 2014

Direct In Vivo Human Intestinal Permeability (Peff ) Determined with Different Clinical Perfusion and Intubation Methods

scientific article

Effects of verapamil on the pharmacokinetics and hepatobiliary disposition of fexofenadine in pigs

scientific article published on 27 September 2013

Excised segments of rat small intestine in Ussing chamber studies: A comparison of native and stripped tissue viability and permeability to drugs.

scientific article published on 9 April 2016

Hepatic disposition of ximelagatran and its metabolites in pig; prediction of the impact of membrane transporters through a simple disposition model.

scientific article published on 6 February 2010

Human in vivo regional intestinal permeability: quantitation using site-specific drug absorption data

scientific article published on 6 May 2015

In Silico Modeling of Gastrointestinal Drug Absorption: Predictive Performance of Three Physiologically Based Absorption Models.

scientific article

In Vivo Drug Delivery Performance of Lipiodol-Based Emulsion or Drug-Eluting Beads in Patients with Hepatocellular Carcinoma.

scientific article published on 20 December 2016

In Vivo Mechanisms of Intestinal Drug Absorption from Aprepitant Nanoformulations

scientific article published on 24 July 2017

In Vivo Predictive Dissolution (IPD) and Biopharmaceutical Modeling and Simulation: Future Use of Modern Approaches and Methodologies in a Regulatory Context.

scientific article published on 14 February 2017

In vivo methods for drug absorption - comparative physiologies, model selection, correlations with in vitro methods (IVIVC), and applications for formulation/API/excipient characterization including food effects.

scientific article published on 15 March 2014

Lipiodol does not affect the tissue distribution of intravenous doxorubicin infusion in pigs

scientific article published on 23 November 2016

Online capillary solid phase extraction and liquid chromatographic separation with quantitative tandem mass spectrometric detection (SPE-LC-MS/MS) of ximelagatran and its metabolites in a complex matrix.

scientific article

Optimal experimental design for assessment of enzyme kinetics in a drug discovery screening environment.

scientific article published on 2 February 2011

Optimized Experimental Design for the Estimation of Enzyme Kinetic Parameters: An Experimental Evaluation ⬇️

scientific article published on August 31, 2012

PBPK models for the prediction of in vivo performance of oral dosage forms

scientific article published in European Journal of Pharmaceutical Sciences in June 2014

Pharmacokinetics of an injectable modified-release 2-hydroxyflutamide formulation in the human prostate gland using a semiphysiologically based biopharmaceutical model

scientific article published on 7 August 2014

Preclinical Effect of Absorption Modifying Excipients on Rat Intestinal Transport of Model Compounds and the Mucosal Barrier Marker 51Cr-EDTA.

scientific article published on 24 July 2017

Preclinical characterization of three transient receptor potential vanilloid receptor 1 antagonists for early use in human intradermal microdose analgesic studies.

scientific article published on 26 January 2018

Pulmonary Dissolution of Poorly Soluble Compounds Studied in an ex Vivo Rat Lung Model

scientific article published on 11 June 2019

Pulmonary absorption - estimation of effective pulmonary permeability and tissue retention of ten drugs using an ex-vivo rat model and computational analysis

scientific article published on 27 November 2017

Regional Intestinal Permeability in Dogs: Biopharmaceutical Aspects for Development of Oral Modified-Release Dosage Forms

scientific article published on 8 August 2016

Regional Intestinal Permeability in Rats: A Comparison of Methods.

scientific article published on 18 September 2017

Regional Intestinal Permeability of Three Model Drugs in Human

article

Reply to "Comment on 'In Silico Modeling of Gastrointestinal Drug Absorption: Predictive Performance of Three Physiologically Based Absorption Models'".

scientific article published on 16 December 2016

Reply to "Comment on 'In Vivo Drug Delivery Performance of Lipiodol-Based Emulsion or Drug-Eluting Beads in Patients with Hepatocellular Carcinoma'".

scientific article published on 29 November 2017

The effects of lipiodol and cyclosporin A on the hepatobiliary disposition of doxorubicin in pigs

scientific article published on 07 March 2014

The multiple depletion curves method provides accurate estimates of intrinsic clearance (CLint), maximum velocity of the metabolic reaction (Vmax), and Michaelis constant (Km): accuracy and robustness evaluated through experimental data and Monte Ca

scientific article

The pharmacokinetics and hepatic disposition of repaglinide in pigs: mechanistic modeling of metabolism and transport.

scientific article published on 6 March 2012

Treatment of intermediate stage hepatocellular carcinoma: a review of intrahepatic doxorubicin drug-delivery systems

scientific article

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