List of works - Zhiqing Liu

Antimicrobial and Antioxidant Polyketides from a Deep-Sea-Derived Fungus <i>Aspergillus versicolor</i> SH0105

scientific article published on 11 December 2020

BH4 domain of Bcl-2 as a novel target for cancer therapy

scientific article published on 26 November 2015

Design, Synthesis, and Pharmacological Evaluation of Analogues Derived from the PLEV Tetrapeptide as Protein-Protein Interaction Modulators of Voltage-Gated Sodium Channel 1.6.

scientific article published on 15 October 2020

Design, synthesis and pharmacological evaluation of 2-(thiazol-2-amino)-4-arylaminopyrimidines as potent anaplastic lymphoma kinase (ALK) inhibitors.

scientific article published on 4 September 2014

Design, synthesis, and pharmacological evaluation of benzamide derivatives as glucokinase activators.

scientific article

Direct Activation of Bax Protein for Cancer Therapy

scientific article

Discovery of novel 2,4-diarylaminopyrimidine analogues (DAAPalogues) showing potent inhibitory activities against both wild-type and mutant ALK kinases.

scientific article published on 8 May 2014

Discovery of phenanthridine analogues as novel chemical probes disrupting the binding of DNA to ΔFosB homodimers and ΔFosB/JunD heterodimers

scientific article published on 06 June 2020

Discovery of potent and selective BRD4 inhibitors capable of blocking TLR3-induced acute airway inflammation

scientific article published on 03 April 2018

Efficacy of Novel Highly Specific Bromodomain-Containing Protein 4 Inhibitors in Innate Inflammation-Driven Airway Remodeling

scientific article published on 01 January 2019

Exchange proteins directly activated by cAMP (EPACs): Emerging therapeutic targets

scientific article published on 27 February 2017

Functional Modulation of Voltage-Gated Sodium Channels by a FGF14-Based Peptidomimetic.

scientific article

Identification of novel 2-(benzo[d]isoxazol-3-yl)-2-oxo-N-phenylacetohydrazonoyl cyanide analoguesas potent EPAC antagonists

scientific article published on 4 April 2017

Identification of peptidomimetics as novel chemical probes modulating fibroblast growth factor 14 (FGF14) and voltage-gated sodium channel 1.6 (Nav1.6) protein-protein interactions

scientific article published on 15 December 2018

Mucosal Bromodomain-Containing Protein 4 (BRD4) Mediates Aeroallergen-induced Inflammation and Remodeling

scientific article published on 13 October 2018

Novel 2,4-Diarylaminopyrimidine Analogues (DAAPalogues) Showing Potent c-Met/ALK Multikinase Inhibitory Activities

scientific article

Pharmacoproteomics reveal novel protective activity of bromodomain containing 4 inhibitors on vascular homeostasis in TLR3-mediated airway remodeling

scientific article published on 10 June 2019

Selective Antagonists of the Bronchiolar Epithelial NF-κB-Bromodomain-Containing Protein 4 Pathway in Viral-Induced Airway Inflammation

scientific article published in April 2018

Structure-Activity Relationship Studies of Substituted 2-(Isoxazol-3-yl)-2-oxo-N'-phenyl-acetohydrazonoyl Cyanide Analogues: Identification of Potent Exchange Proteins Directly Activated by cAMP (EPAC) Antagonists

scientific article published on 16 July 2015

Structure-activity relationships of 2-substituted phenyl-N-phenyl-2-oxoacetohydrazonoyl cyanides as novel antagonists of exchange proteins directly activated by cAMP (EPACs).

scientific article published on 25 October 2017

Structure-guided drug design identifies a BRD4-selective small molecule that suppresses HIV

scientific article published on 22 July 2019

Synthesis and Biochemical Evaluation of Non-Cyclic Nucleotide Exchange Protein Directly Activated by cAMP 1 (EPAC1) Regulators

scientific article published on 28 April 2020

List of works by Zhiqing Liu

Antimicrobial and Antioxidant Polyketides from a Deep-Sea-Derived Fungus <i>Aspergillus versicolor</i> SH0105

BH4 domain of Bcl-2 as a novel target for cancer therapy

Design, Synthesis, and Pharmacological Evaluation of Analogues Derived from the PLEV Tetrapeptide as Protein-Protein Interaction Modulators of Voltage-Gated Sodium Channel 1.6.

Design, synthesis and pharmacological evaluation of 2-(thiazol-2-amino)-4-arylaminopyrimidines as potent anaplastic lymphoma kinase (ALK) inhibitors.

Design, synthesis, and pharmacological evaluation of benzamide derivatives as glucokinase activators.

Direct Activation of Bax Protein for Cancer Therapy

Discovery of novel 2,4-diarylaminopyrimidine analogues (DAAPalogues) showing potent inhibitory activities against both wild-type and mutant ALK kinases.

Discovery of phenanthridine analogues as novel chemical probes disrupting the binding of DNA to ΔFosB homodimers and ΔFosB/JunD heterodimers

Discovery of potent and selective BRD4 inhibitors capable of blocking TLR3-induced acute airway inflammation

Efficacy of Novel Highly Specific Bromodomain-Containing Protein 4 Inhibitors in Innate Inflammation-Driven Airway Remodeling

Exchange proteins directly activated by cAMP (EPACs): Emerging therapeutic targets

Functional Modulation of Voltage-Gated Sodium Channels by a FGF14-Based Peptidomimetic.

Identification of novel 2-(benzo[d]isoxazol-3-yl)-2-oxo-N-phenylacetohydrazonoyl cyanide analoguesas potent EPAC antagonists

Identification of peptidomimetics as novel chemical probes modulating fibroblast growth factor 14 (FGF14) and voltage-gated sodium channel 1.6 (Nav1.6) protein-protein interactions

Mucosal Bromodomain-Containing Protein 4 (BRD4) Mediates Aeroallergen-induced Inflammation and Remodeling

Novel 2,4-Diarylaminopyrimidine Analogues (DAAPalogues) Showing Potent c-Met/ALK Multikinase Inhibitory Activities

Pharmacoproteomics reveal novel protective activity of bromodomain containing 4 inhibitors on vascular homeostasis in TLR3-mediated airway remodeling

Selective Antagonists of the Bronchiolar Epithelial NF-κB-Bromodomain-Containing Protein 4 Pathway in Viral-Induced Airway Inflammation

Structure-Activity Relationship Studies of Substituted 2-(Isoxazol-3-yl)-2-oxo-N'-phenyl-acetohydrazonoyl Cyanide Analogues: Identification of Potent Exchange Proteins Directly Activated by cAMP (EPAC) Antagonists

Structure-activity relationships of 2-substituted phenyl-N-phenyl-2-oxoacetohydrazonoyl cyanides as novel antagonists of exchange proteins directly activated by cAMP (EPACs).

Structure-guided drug design identifies a BRD4-selective small molecule that suppresses HIV

Synthesis and Biochemical Evaluation of Non-Cyclic Nucleotide Exchange Protein Directly Activated by cAMP 1 (EPAC1) Regulators