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List of works by Jia Zhou

Allosteric Modulation of Class A GPCRs: Targets, Agents, and Emerging Concepts

scientific article published on 28 August 2018

BH4 domain of Bcl-2 as a novel target for cancer therapy

scientific article published on 26 November 2015

Bidirectional Modulation of the Voltage-Gated Sodium (Nav1.6) Channel by Rationally Designed Peptidomimetics

scientific article published on 24 July 2020

Broad Spectrum Antiviral Agent Niclosamide and Its Therapeutic Potential

scientific article published on 10 March 2020

Design, Synthesis, and Biological Evaluation of Substituted 4,6-Dihydrospiro[[1,2,3]triazolo[4,5-b]pyridine-7,3'-indoline]-2',5(3H)-dione Analogues as Potent NS4B Inhibitors for the Treatment of Dengue Virus Infection

scientific article published on 23 August 2019

Design, Synthesis, and Characterization of 4-Undecylpiperidine-2-carboxamides as Positive Allosteric Modulators of the Serotonin (5-HT) 5-HT2C Receptor.

scientific article published on 5 April 2018

Design, Synthesis, and Pharmacological Evaluation of Analogues Derived from the PLEV Tetrapeptide as Protein-Protein Interaction Modulators of Voltage-Gated Sodium Channel 1.6.

scientific article published on 15 October 2020

Discovery and development of natural product oridonin-inspired anticancer agents

scientific article

Discovery of Novel Substituted N-(4-Amino-2-chlorophenyl)-5-chloro-2-hydroxybenzamide Analogues as Potent Human Adenovirus Inhibitors

scientific article published on 28 October 2020

Discovery of Potent and Brain-Penetrant GPR52 Agonist that Suppresses Psychostimulant Behavior

scientific article published on 16 November 2020

Discovery of niclosamide and its O-alkylamino-tethered derivatives as potent antibacterial agents against carbapenemase-producing and/or colistin resistant Enterobacteriaceae isolates

scientific article published on 23 March 2019

Discovery of potent and selective BRD4 inhibitors capable of blocking TLR3-induced acute airway inflammation

scientific article published on 03 April 2018

Drug Discovery Targeting Bromodomain-Containing Protein 4.

scientific article

Drug repurposing approach to combating coronavirus: Potential drugs and drug targets

scientific article published on 05 December 2020

Efficacy of Novel Aminooxyacetic Acid Prodrugs in Colon Cancer Models: Towards Clinical Translation of the Cystathionine β-Synthase Inhibition Concept

scientific article published in 2021

Emerging roles of SIRT6 in human diseases and its modulators

scientific article published on 16 December 2020

Erythrosin B is a potent and broad-spectrum orthosteric inhibitor of the flavivirus NS2B-NS3 protease

scientific article published on 27 December 2017

Exchange Protein Directly Activated by cAMP Modulates Ebola Virus Uptake into Vascular Endothelial Cells

scholarly article by Aleksandra Drelich published in October 2018

Functional Modulation of Voltage-Gated Sodium Channels by a FGF14-Based Peptidomimetic.

scientific article

Identification of novel 2-(benzo[d]isoxazol-3-yl)-2-oxo-N-phenylacetohydrazonoyl cyanide analoguesas potent EPAC antagonists

scientific article published on 4 April 2017

Identification of peptidomimetics as novel chemical probes modulating fibroblast growth factor 14 (FGF14) and voltage-gated sodium channel 1.6 (Nav1.6) protein-protein interactions

scientific article published on 15 December 2018

Intestinal microbiota-derived short-chain fatty acids regulation of immune cell IL-22 production and gut immunity

scientific article published on 08 September 2020

JMX0207, a Niclosamide Derivative with Improved Pharmacokinetics, Suppresses Zika Virus Infection Both In Vitro and In Vivo

scientific article published on 21 September 2020

Longitudinal single-cell profiling reveals molecular heterogeneity and tumor-immune evolution in refractory mantle cell lymphoma

scientific article published on 17 May 2021

Luteolin-Mediated Inhibition of Hepatic Stellate Cell Activation via Suppression of the STAT3 Pathway.

scientific article published on 24 May 2018

Mechanism of Action of an EPAC1-Selective Competitive Partial Agonist

scientific article published on 16 April 2020

Molecular targeting therapies for neuroblastoma: Progress and challenges

scientific article published on 06 November 2020

Orphan Receptor GPR88 as an Emerging Neurotherapeutic Target

scientific article published on 20 December 2018

Positive-allosteric modulation of the 5-HT2C receptor: implications for neuropsychopharmacology and neurotherapeutics

scientific article published on 01 January 2019

Regio- and Stereospecific Synthesis of Oridonin D-Ring Aziridinated Analogues for the Treatment of Triple-Negative Breast Cancer via Mediated Irreversible Covalent Warheads.

scientific article published on 12 March 2018

Small Molecules Selectively Targeting Sigma-1 Receptor for the Treatment of Neurological Diseases

scientific article published on 28 October 2020

Small-molecule inhibitors for the Prp8 intein as antifungal agents

scientific article published on 01 January 2021

Structure-Activity Relationship Studies on Diversified Salicylamide Derivatives as Potent Inhibitors of Human Adenovirus Infection

scientific article published on 28 February 2020

Structure-activity relationships of 2-substituted phenyl-N-phenyl-2-oxoacetohydrazonoyl cyanides as novel antagonists of exchange proteins directly activated by cAMP (EPACs).

scientific article published on 25 October 2017

Synthesis and Biochemical Evaluation of Non-Cyclic Nucleotide Exchange Protein Directly Activated by cAMP 1 (EPAC1) Regulators

scientific article published on 28 April 2020

Synthesis and Pharmacological Evaluation of Noncatechol G Protein Biased and Unbiased Dopamine D1 Receptor Agonists

scientific article published on 05 April 2019

Targeting MDM2 for Neuroblastoma Therapy: In Vitro and In Vivo Anticancer Activity and Mechanism of Action

scientific article published on 05 December 2020

Therapeutic Potential of Oridonin and Its Analogs: From Anticancer and Antiinflammation to Neuroprotection

scientific article published on 22 February 2018

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