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List of works by Stephen D. Weeks

A Carrier Protein Strategy Yields the Structure of Dalbavancin

scientific article

Acylated sulfonamide adenosines as potent inhibitors of the adenylate-forming enzyme superfamily

scientific article published on 17 April 2019

Characterization of Mutants of Human Small Heat Shock Protein HspB1 Carrying Replacements in the N-Terminal Domain and Associated with Hereditary Motor Neuron Diseases

scientific article

Characterization of human small heat shock protein HSPB1 α-crystallin domain localized mutants associated with hereditary motor neuron diseases.

scientific article published on 12 January 2018

Characterization of oligosaccharides from the chondroitin sulfates. (1)H-NMR and (13)C-NMR studies of reduced disaccharides and tetrasaccharides.

scientific article

Comparative analysis of pyrimidine substituted aminoacyl-sulfamoyl nucleosides as potential inhibitors targeting class I aminoacyl-tRNA synthetases

scientific article published on 05 April 2019

Crystal structures of Lys-63-linked tri- and di-ubiquitin reveal a highly extended chain architecture

scientific article

Crystal structures of the Pyrococcus abyssi Sm core and its complex with RNA. Common features of RNA binding in archaea and eukarya

scientific article

Discovery of a new Pro-Pro endopeptidase, PPEP-2, provides mechanistic insights into the differences in substrate specificity within the PPEP family

scientific article published in Journal of Biological Chemistry

Dissecting the functional role of the N-terminal domain of the human small heat shock protein HSPB6.

scientific article

Elucidation of the molecular mechanisms of two nanobodies that inhibit thrombin-activatable fibrinolysis inhibitor activation and activated thrombin-activatable fibrinolysis inhibitor activity

scientific article

Expression, purification and preliminary biochemical and structural characterization of the leucine rich repeat namesake domain of leucine rich repeat kinase 2.

scientific article

Family-wide analysis of aminoacyl-sulfamoyl-3-deazaadenosine analogues as inhibitors of aminoacyl-tRNA synthetases.

scientific article published on 14 February 2018

Heptyl α-D-mannosides grafted on a β-cyclodextrin core to interfere with Escherichia coli adhesion: an in vivo multivalent effect

scientific article published on 17 April 2013

Interaction of transportin-SR2 with Ras-related nuclear protein (Ran) GTPase

scientific article published on 22 July 2013

MALT1 auto-proteolysis is essential for NF-κB-dependent gene transcription in activated lymphocytes

scientific article

Molecular mechanism of two nanobodies that inhibit PAI-1 activity reveals a modulation at distinct stages of the PAI-1/plasminogen activator interaction

scientific article published on 20 February 2020

Molecular structure and dynamics of the dimeric human small heat shock protein HSPB6

scientific article

Rational design of an XNA ligase through docking of unbound nucleic acids to toroidal proteins

scientific article published on 01 July 2019

Real-time monitoring of the membrane-binding and insertion properties of the cholesterol-dependent cytolysin anthrolysin O from Bacillus anthracis.

scientific article published in July 2006

SUMO fusions and SUMO-specific protease for efficient expression and purification of proteins.

scientific article

Small-angle X-ray scattering to obtain models of multivalent lectin-glycan complexes.

scientific article published in January 2014

Specific sequences in the N-terminal domain of human small heat-shock protein HSPB6 dictate preferential hetero-oligomerization with the orthologue HSPB1. ⬇️

scientific article

Structural Basis for the Interaction of a Human Small Heat Shock Protein with the 14-3-3 Universal Signaling Regulator

scientific article published on 30 December 2016

Structural Insights into the Binding of Natural Pyrimidine-Based Inhibitors of Class II Aminoacyl-tRNA Synthetases

scientific article published on 08 January 2020

Structural Insights into the Mechanism of a Nanobody That Stabilizes PAI-1 and Modulates Its Activity

scientific article published on 15 August 2020

Structural basis of bacterial defense against g-type lysozyme-based innate immunity

scientific article

Structural insights into the activity and regulation of human Josephin-2

scientific article published on 01 July 2019

Structure of Ostertagia ostertagi ASP-1: insights into disulfide-mediated cyclization and dimerization

scientific article

Synthesis and Biological Evaluation of 1,3-Dideazapurine-Like 7-Amino-5-Hydroxymethyl-Benzimidazole Ribonucleoside Analogues as Aminoacyl-tRNA Synthetase Inhibitors

scientific article published on 16 October 2020

The Role of the Arginine in the Conserved N-Terminal Domain RLFDQxFG Motif of Human Small Heat Shock Proteins HspB1, HspB4, HspB5, HspB6, and HspB8

scientific article published on 20 July 2018

The preferential heterodimerization of human small heat shock proteins HSPB1 and HSPB6 is dictated by the N-terminal domain ⬇️

scientific article published on 4 October 2016

Three-Dimensional Structure of α-Crystallin Domain Dimers of Human Small Heat Shock Proteins HSPB1 and HSPB6 ⬇️

scientific article published on May 30, 2011

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