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List of works by Nuno Miguel Pires

Activation of nuclear receptor Nur77 by 6-mercaptopurine protects against neointima formation.

scientific article published on 22 January 2007

Apolipoprotein C-I is crucially involved in lipopolysaccharide-induced atherosclerosis development in apolipoprotein E-knockout mice.

scientific article published on 22 October 2007

Blood pressure decrease in spontaneously hypertensive rats folowing renal denervation or dopamine β-hydroxylase inhibition with etamicastat.

scientific article published on 9 April 2015

Blood pressure-decreasing effect of etamicastat alone and in combination with antihypertensive drugs in the spontaneously hypertensive rat

scientific article published on 09 October 2014

Carbamazepine aggravates absence seizures in two dedicated mouse models

scientific article published on 23 March 2015

Carbamazepine and oxcarbazepine, but not eslicarbazepine, enhance excitatory synaptic transmission onto hippocampal CA1 pyramidal cells through an antagonist action at adenosine A1 receptors

scientific article published on 3 February 2015

Cardiovascular safety pharmacology profile of etamicastat, a novel peripheral selective dopamine-β-hydroxylase inhibitor

scientific article published on 30 January 2015

Characterization of the interaction of the novel antihypertensive etamicastat with human dopamine-β-hydroxylase: comparison with nepicastat.

scientific article

Discovery of a Potent, Long-Acting, and CNS-Active Inhibitor (BIA 10-2474) of Fatty Acid Amide Hydrolase

scientific article published on 11 September 2018

Drug-eluting stents: results, promises and problems.

scientific article

Early systemic inflammatory response to drug-eluting stents implantation: the heart of the difference? Editorial to: "Comparison of changes in early inflammatory markers between sirolimus- and paclitaxel-eluting stent implantation" by Li et al.

scientific article

Eslicarbazepine acetate for the treatment of focal epilepsy: an update on its proposed mechanisms of action

scientific article published on 30 March 2015

Eslicarbazepine and the enhancement of slow inactivation of voltage-gated sodium channels: a comparison with carbamazepine, oxcarbazepine and lacosamide.

scientific article published on 19 September 2014

Genetic Inflammatory Factors Predict Restenosis After Percutaneous Coronary Interventions

article

Histopathologic alterations following local delivery of dexamethasone to inhibit restenosis in murine arteries

scientific article published on 15 July 2005

Increased arterial blood pressure and vascular remodeling in mice lacking salt-inducible kinase 1 (SIK1).

scientific article published on 2 January 2015

Inhibition of neointima formation by local delivery of estrogen receptor alpha and beta specific agonists

scientific article published on 10 November 2006

Lack of salt-inducible kinase 2 (SIK2) prevents the development of cardiac hypertrophy in response to chronic high-salt intake.

scientific article

Lipoprotein Lipase Gene Polymorphisms and the Risk of Target Vessel Revascularization After Percutaneous Coronary Intervention

article

Local perivascular delivery of anti-restenotic agents from a drug-eluting poly(epsilon-caprolactone) stent cuff

scientific article published in September 2005

Preclinical pharmacological evaluation of the fatty acid amide hydrolase inhibitor BIA 10-2474

scientific article published on 12 February 2020

Role of P-glycoprotein and permeability upon the brain distribution and pharmacodynamics of etamicastat: a comparison with nepicastat.

scientific article published on 27 April 2015

Short-term dexamethasone treatment inhibits vein graft thickening in hypercholesterolemic ApoE3Leiden transgenic mice

scientific article published on 01 April 2006

Sirolimus and paclitaxel provoke different vascular pathological responses after local delivery in a murine model for restenosis on underlying atherosclerotic arteries.

scientific article published on 20 April 2007

Targeting pharmacoresistant epilepsy and epileptogenesis with a dual-purpose antiepileptic drug

scientific article published on 2 December 2014

The effect of interleukin-10 knock-out and overexpression on neointima formation in hypercholesterolemic APOE*3-Leiden mice

The influence of established genetic variation in the haemostatic system on clinical restenosis after percutaneous coronary interventions

Tumor necrosis factor-alpha plays an important role in restenosis development

scientific article published in December 2005

Vitamin D receptor: a new risk marker for clinical restenosis after percutaneous coronary intervention

scientific article published in March 2010