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Authors whose works are in public domain in at least one jurisdiction

List of works by Joana Soares

1-16 of 16 results

New insights into cancer‐related proteins provided by the yeast model

scientific article published on February 10, 2012

Oxazoloisoindolinones with in vitro antitumor activity selectively activate a p53-pathway through potential inhibition of the p53-MDM2 interaction.

scientific article published on 13 October 2014

A tryptophanol-derived oxazolopiperidone lactam is cytotoxic against tumors via inhibition of p53 interaction with murine double minute proteins.

scientific article published on 23 March 2015

p53 and glucose metabolism: an orchestra to be directed in cancer therapy

scientific article published on 23 March 2018

Medicinal Chemistry Strategies to Disrupt the p53-MDM2/MDMX Interaction.

scientific article published on 15 June 2016

Reactivation of wild-type and mutant p53 by tryptophanolderived oxazoloisoindolinone SLMP53-1, a novel anticancer small-molecule

scientific article published on 28 December 2015

DIMP53-1: a novel small-molecule dual inhibitor of p53-MDM2/X interactions with multifunctional p53-dependent anticancer properties.

scientific article

Contribution of yeast models to neurodegeneration research

scientific article published on 15 July 2012

Novel simplified yeast-based assays of regulators of p53-MDMX interaction and p53 transcriptional activity.

scientific article

Studying p53 family proteins in yeast: induction of autophagic cell death and modulation by interactors and small molecules.

scientific article published on 28 September 2014

New therapeutic strategies for cancer and neurodegeneration emerging from yeast cell-based systems.

scientific article published on January 2012

Enhanced cytotoxicity of prenylated chalcone against tumour cells via disruption of the p53-MDM2 interaction.

scientific article published on 14 October 2015

New inhibitor of the TAp73 interaction with MDM2 and mutant p53 with promising antitumor activity against neuroblastoma

scientific article published on 19 January 2019

p53 family interactions and yeast: together in anticancer therapy.

scientific article published on 15 February 2016

Improving anticancer activity towards colon cancer cells with a new p53-activating agent

scientific article published on 06 September 2018

Aspartic vinyl sulfones: Inhibitors of a caspase-3-dependent pathway

scientific article published on 05 March 2011