List of works - Hans Prenen

A new intraductal radiofrequency ablation device for inoperable biliopancreatic tumors complicated by obstructive jaundice: the IGNITE-1 study

scientific article published on 21 July 2017

A phase I/II, open-label, randomised study of nintedanib plus mFOLFOX6 versus bevacizumab plus mFOLFOX6 in first-line metastatic colorectal cancer patients.

scientific article published on 12 August 2015

Activity of dasatinib, a dual SRC/ABL kinase inhibitor, and IPI-504, a heat shock protein 90 inhibitor, against gastrointestinal stromal tumor-associated PDGFRAD842V mutation.

scientific article published on September 2008

Administration of imatinib mesylate in rats impairs the neonatal development of intramuscular interstitial cells in bladder and results in altered contractile properties

scientific article published on 24 April 2013

Analysis of the formalin-fixed paraffin-embedded tissue proteome: pitfalls, challenges, and future prospectives.

scientific article

Bevacizumab plus chemotherapy as salvage treatment in chemorefractory patients with metastatic colorectal cancer ⬇️

scientific article published on January 25, 2013

Biologic modulation of chemotherapy in patients with hepatic colorectal metastases: The role of anti‐VEGF and anti‐EGFR antibodies ⬇️

scientific article published on December 15, 2010

Breast tumors interfere with endothelial TRAIL at the premetastatic niche to promote cancer cell seeding

scientific article published in 2023

Cancer risk in immune-mediated inflammatory diseases (IMID).

scientific article published on 29 August 2013

Common variants at the MHC locus and at chromosome 16q24.1 predispose to Barrett's esophagus

scientific article

Comparison of multiple protein extraction buffers for GeLC-MS/MS proteomic analysis of liver and colon formalin-fixed, paraffin-embedded tissues.

scientific article published on 17 December 2015

Copy number load predicts outcome of metastatic colorectal cancer patients receiving bevacizumab combination therapy

scientific article published in Nature Communications

Current and future biomarkers in the treatment of colorectal cancer.

scientific article published on 05 December 2016

Docetaxel plus oxaliplatin with or without fluorouracil or capecitabine in metastatic or locally recurrent gastric cancer: a randomized phase II study.

scientific article published on January 2015

Efficacy of the kinase inhibitor SU11248 against gastrointestinal stromal tumor mutants refractory to imatinib mesylate

scientific article

Emerging role of tyrosine kinase inhibitors in the treatment of advanced renal cell cancer: a review.

scientific article

Endothelial deficiency of L1 reduces tumor angiogenesis and promotes vessel normalization

scientific article

Endothelial deficiency of L1 reduces tumor angiogenesis and promotes vessel normalization

Establishment of a mouse gastrointestinal stromal tumour model and evaluation of response to imatinib by small animal positron emission tomography

scientific article published on March 2006

Expression of FOXP1 and Colorectal Cancer Prognosis

scientific article published on January 2015

Gastric cancer

scientific article published on 05 May 2016

Genome-wide association studies in oesophageal adenocarcinoma and Barrett's oesophagus: a large-scale meta-analysis ⬇️

scientific article

Germline variation in inflammation-related pathways and risk of Barrett's oesophagus and oesophageal adenocarcinoma

scientific article published on 2 August 2016

Hypomagnesaemia and targeted anti-epidermal growth factor receptor (EGFR) agents ⬇️

scientific article published on November 24, 2011

Imatinib for the treatment of patients with unresectable or metastatic malignant KIT-positive gastrointestinal stromal tumours: an open-label Belgian trial

scientific article published on 01 October 2006

Intrahepatic therapy for liver-dominant metastatic colorectal cancer

scientific article

Iron deficiency in gastrointestinal oncology

scientific article

Is There Merit for MET-Targeted Therapies in Gastroesophageal Cancer?

scientific article published on 14 September 2017

Lessons From the Adjuvant Bevacizumab Trial on Colon Cancer: What Next?

scientific article published on 29 November 2010

MET is required for the recruitment of anti-tumoural neutrophils

scientific article

Macrophage Metabolism Controls Tumor Blood Vessel Morphogenesis and Metastasis

scientific article

Management of adverse events during treatment of gastrointestinal cancers with epidermal growth factor inhibitors.

scientific article published on 11 April 2017

Mechanisms of resistance to imatinib mesylate in gastrointestinal stromal tumors and activity of the PKC412 inhibitor against imatinib-resistant mutants

scientific article

Microsatellite instable vs stable colon carcinomas: analysis of tumour heterogeneity, inflammation and angiogenesis

scientific article

Minimally invasive liver surgery for metastases from colorectal cancer: oncologic outcome and prognostic factors.

scientific article published on 7 February 2012

Molecular genetics of colorectal cancer

scientific article published on January 2014

Molecular pathogenesis of multiple gastrointestinal stromal tumors in NF1 patients

scientific article

Oncological Management of Unresectable Liver Metastases ⬇️

scientific article published on November 23, 2012

PD-030Prospective non-interventional study to collect data on the use of bevacizumab and conventional chemotherapy for the treatment of previously untreated metastatic colorectal cancer in patient's ≥70 years.

scientific article

PHD1 regulates p53-mediated colorectal cancer chemoresistance.

scientific article published on 19 August 2015

Phase I study of FOLFIRI plus pimasertib as second-line treatment for KRAS-mutated metastatic colorectal cancer

scientific article

Phase II open-label study to assess efficacy and safety of lenalidomide in combination with cetuximab in KRAS-mutant metastatic colorectal cancer

scientific article (publication date: 2013)

Phospholipase C gamma 1 (PLCG1) R707Q mutation is counterselected under targeted therapy in a patient with hepatic angiosarcoma

scientific article published on 10 October 2015

Polymorphisms near TBX5 and GDF7 are associated with increased risk for Barrett's esophagus ⬇️

scientific article

Postgastrectomy protein-losing cytomegalovirus jejunitis in an immunocompromised patient.

scientific article published on 14 October 2014

Preclinical and clinical evaluation of MET functions in cancer cells and in the tumor stroma.

scientific article published on 21 March 2016

Progression of Barrett's esophagus toward esophageal adenocarcinoma: an overview

scientific article published on 30 September 2016

Proteomic analysis of formalin-fixed paraffin-embedded colorectal cancer tissue using tandem mass tag protein labeling.

scientific article published on November 2013

Pulmonary lymphangitic carcinomatosis as a primary manifestation of gastric carcinoma in a young adult: a case report and review of the literature

scientific article

RANK-RANKL Signaling in Cancer of the Uterine Cervix: A Review. ⬇️

scientific article published on 2 May 2019

RANK/RANKL signaling inhibition may improve the effectiveness of checkpoint blockade in cancer treatment

scientific article published on 03 November 2018

Radiological imaging markers predicting clinical outcome in patients with metastatic colorectal carcinoma treated with regorafenib: post hoc analysis of the CORRECT phase III trial (RadioCORRECT study).

scientific article

Refractory Metastatic Colorectal Cancer: Current Challenges and Future Prospects

scientific article published on 15 July 2020

Relevance of Geriatric Assessment in Older Patients With Colorectal Cancer.

scientific article published on 8 August 2016

Role of targeted agents in metastatic colorectal cancer.

scientific article published on 05 May 2013

Safety and efficacy of doxorubicin-eluting superabsorbent polymer microspheres for the treatment of liver metastases from neuroendocrine tumours: preliminary results

scientific article published on 22 February 2017

Salivary gland carcinomas: molecular abnormalities as potential therapeutic targets.

scientific article published on May 2008

Simultaneous determination of AMN107 and Imatinib (Gleevec, Glivec, STI571) in cultured tumour cells using an isocratic high-performance liquid chromatography procedure with UV detection

scientific article published on 07 September 2006

Specialized Blood Collection Tubes for Liquid Biopsy: Improving the Pre-analytical Conditions

scientific article published on 01 February 2020

Successful application of endoscopic ultrasound-guided fine needle biopsy to establish pancreatic patient-derived tumor xenografts: a pilot study

scientific article published on 14 September 2016

Survival Outcomes in Patients With RAS Wild Type Metastatic Colorectal Cancer Classified According to Köhne Prognostic Category and BRAF Mutation Status

scientific article published on 28 September 2017

Tenckhoff tunneled peritoneal catheter placement in the palliative treatment of malignant ascites: technical results and overall clinical outcome.

scientific article published on 7 February 2016

The impact of frailty on postoperative outcomes in individuals aged 65 and over undergoing elective surgery for colorectal cancer: A systematic review

scientific article published on 20 June 2016

The mTOR and PP2A Pathways Regulate PHD2 Phosphorylation to Fine-Tune HIF1α Levels and Colorectal Cancer Cell Survival under Hypoxia.

scientific article published on February 2017

Tumour-educated circulating monocytes are powerful candidate biomarkers for diagnosis and disease follow-up of colorectal cancer

scientific article published on 26 March 2015

Use of biologics and chemotherapy in patients with inflammatory bowel diseases and cancer

scientific article

Yttrium-90 radioembolization for the treatment of chemorefractory colorectal liver metastases: Technical results, clinical outcome and factors potentially influencing survival.

scientific article published on December 2015

List of works by Hans Prenen

A new intraductal radiofrequency ablation device for inoperable biliopancreatic tumors complicated by obstructive jaundice: the IGNITE-1 study

A phase I/II, open-label, randomised study of nintedanib plus mFOLFOX6 versus bevacizumab plus mFOLFOX6 in first-line metastatic colorectal cancer patients.

Activity of dasatinib, a dual SRC/ABL kinase inhibitor, and IPI-504, a heat shock protein 90 inhibitor, against gastrointestinal stromal tumor-associated PDGFRAD842V mutation.

Administration of imatinib mesylate in rats impairs the neonatal development of intramuscular interstitial cells in bladder and results in altered contractile properties

Analysis of the formalin-fixed paraffin-embedded tissue proteome: pitfalls, challenges, and future prospectives.

Bevacizumab plus chemotherapy as salvage treatment in chemorefractory patients with metastatic colorectal cancer ⬇️

Biologic modulation of chemotherapy in patients with hepatic colorectal metastases: The role of anti‐VEGF and anti‐EGFR antibodies ⬇️

Breast tumors interfere with endothelial TRAIL at the premetastatic niche to promote cancer cell seeding

Cancer risk in immune-mediated inflammatory diseases (IMID).

Common variants at the MHC locus and at chromosome 16q24.1 predispose to Barrett's esophagus

Comparison of multiple protein extraction buffers for GeLC-MS/MS proteomic analysis of liver and colon formalin-fixed, paraffin-embedded tissues.

Copy number load predicts outcome of metastatic colorectal cancer patients receiving bevacizumab combination therapy

Current and future biomarkers in the treatment of colorectal cancer.

Docetaxel plus oxaliplatin with or without fluorouracil or capecitabine in metastatic or locally recurrent gastric cancer: a randomized phase II study.

Efficacy of the kinase inhibitor SU11248 against gastrointestinal stromal tumor mutants refractory to imatinib mesylate

Emerging role of tyrosine kinase inhibitors in the treatment of advanced renal cell cancer: a review.

Endothelial deficiency of L1 reduces tumor angiogenesis and promotes vessel normalization

Endothelial deficiency of L1 reduces tumor angiogenesis and promotes vessel normalization

Establishment of a mouse gastrointestinal stromal tumour model and evaluation of response to imatinib by small animal positron emission tomography

Expression of FOXP1 and Colorectal Cancer Prognosis

Gastric cancer

Genome-wide association studies in oesophageal adenocarcinoma and Barrett's oesophagus: a large-scale meta-analysis ⬇️

Germline variation in inflammation-related pathways and risk of Barrett's oesophagus and oesophageal adenocarcinoma

Hypomagnesaemia and targeted anti-epidermal growth factor receptor (EGFR) agents ⬇️

Imatinib for the treatment of patients with unresectable or metastatic malignant KIT-positive gastrointestinal stromal tumours: an open-label Belgian trial

Intrahepatic therapy for liver-dominant metastatic colorectal cancer

Iron deficiency in gastrointestinal oncology

Is There Merit for MET-Targeted Therapies in Gastroesophageal Cancer?

Lessons From the Adjuvant Bevacizumab Trial on Colon Cancer: What Next?

MET is required for the recruitment of anti-tumoural neutrophils

Macrophage Metabolism Controls Tumor Blood Vessel Morphogenesis and Metastasis

Management of adverse events during treatment of gastrointestinal cancers with epidermal growth factor inhibitors.

Mechanisms of resistance to imatinib mesylate in gastrointestinal stromal tumors and activity of the PKC412 inhibitor against imatinib-resistant mutants

Microsatellite instable vs stable colon carcinomas: analysis of tumour heterogeneity, inflammation and angiogenesis

Minimally invasive liver surgery for metastases from colorectal cancer: oncologic outcome and prognostic factors.

Molecular genetics of colorectal cancer

Molecular pathogenesis of multiple gastrointestinal stromal tumors in NF1 patients

Oncological Management of Unresectable Liver Metastases ⬇️

PD-030Prospective non-interventional study to collect data on the use of bevacizumab and conventional chemotherapy for the treatment of previously untreated metastatic colorectal cancer in patient's ≥70 years.

PHD1 regulates p53-mediated colorectal cancer chemoresistance.

Phase I study of FOLFIRI plus pimasertib as second-line treatment for KRAS-mutated metastatic colorectal cancer

Phase II open-label study to assess efficacy and safety of lenalidomide in combination with cetuximab in KRAS-mutant metastatic colorectal cancer

Phospholipase C gamma 1 (PLCG1) R707Q mutation is counterselected under targeted therapy in a patient with hepatic angiosarcoma

Polymorphisms near TBX5 and GDF7 are associated with increased risk for Barrett's esophagus ⬇️

Postgastrectomy protein-losing cytomegalovirus jejunitis in an immunocompromised patient.

Preclinical and clinical evaluation of MET functions in cancer cells and in the tumor stroma.

Progression of Barrett's esophagus toward esophageal adenocarcinoma: an overview

Proteomic analysis of formalin-fixed paraffin-embedded colorectal cancer tissue using tandem mass tag protein labeling.

Pulmonary lymphangitic carcinomatosis as a primary manifestation of gastric carcinoma in a young adult: a case report and review of the literature

RANK-RANKL Signaling in Cancer of the Uterine Cervix: A Review. ⬇️

RANK/RANKL signaling inhibition may improve the effectiveness of checkpoint blockade in cancer treatment

Radiological imaging markers predicting clinical outcome in patients with metastatic colorectal carcinoma treated with regorafenib: post hoc analysis of the CORRECT phase III trial (RadioCORRECT study).

Refractory Metastatic Colorectal Cancer: Current Challenges and Future Prospects

Relevance of Geriatric Assessment in Older Patients With Colorectal Cancer.

Role of targeted agents in metastatic colorectal cancer.

Safety and efficacy of doxorubicin-eluting superabsorbent polymer microspheres for the treatment of liver metastases from neuroendocrine tumours: preliminary results

Salivary gland carcinomas: molecular abnormalities as potential therapeutic targets.

Simultaneous determination of AMN107 and Imatinib (Gleevec, Glivec, STI571) in cultured tumour cells using an isocratic high-performance liquid chromatography procedure with UV detection

Specialized Blood Collection Tubes for Liquid Biopsy: Improving the Pre-analytical Conditions

Successful application of endoscopic ultrasound-guided fine needle biopsy to establish pancreatic patient-derived tumor xenografts: a pilot study

Survival Outcomes in Patients With RAS Wild Type Metastatic Colorectal Cancer Classified According to Köhne Prognostic Category and BRAF Mutation Status

Tenckhoff tunneled peritoneal catheter placement in the palliative treatment of malignant ascites: technical results and overall clinical outcome.

The impact of frailty on postoperative outcomes in individuals aged 65 and over undergoing elective surgery for colorectal cancer: A systematic review

The mTOR and PP2A Pathways Regulate PHD2 Phosphorylation to Fine-Tune HIF1α Levels and Colorectal Cancer Cell Survival under Hypoxia.

Tumour-educated circulating monocytes are powerful candidate biomarkers for diagnosis and disease follow-up of colorectal cancer

Use of biologics and chemotherapy in patients with inflammatory bowel diseases and cancer

Yttrium-90 radioembolization for the treatment of chemorefractory colorectal liver metastases: Technical results, clinical outcome and factors potentially influencing survival.