Search filters

List of works by Viktor Brabec

"Head-to-head" double-hamburger-like structure of di-ruthenated d(GpG) adducts of mono-functional Ru-arene anticancer complexes

scientific article published on 10 November 2016

1,2-GG intrastrand cross-link of antitumor dinuclear bifunctional platinum compound with spermidine linker inhibits DNA polymerization more effectively than the cross-link of conventional cisplatin.

scientific article published on 06 December 2006

3,6-bis(3-alkylguanidino)acridines as DNA-intercalating antitumor agents

scientific article published on 23 September 2012

3-[(E)-(acridin-9'-ylmethylidene)amino]-1-substituted thioureas and their biological activity.

scientific article published on 8 March 2017

A Photoactivatable Platinum(IV) Complex Targeting Genomic DNA and Histone Deacetylases.

scientific article published on 12 October 2015

A Subset of New Platinum Antitumor Agents Kills Cells by a Multimodal Mechanism of Action Also Involving Changes in the Organization of the Microtubule Cytoskeleton

scientific article published on 09 May 2019

A dual-targeting, apoptosis-inducing organometallic half-sandwich iridium anticancer complex.

scientific article published on August 2014

A metal-free DNA nuclease based on a cyclic peptide scaffold.

scientific article published on August 2010

A new 4-(pyridinyl)-4H-benzo[g]chromene-5,10-dione ruthenium(II) complex inducing senescence in 518A2 melanoma cells

scientific article published on 19 June 2019

A potent cytotoxic photoactivated platinum complex

scholarly article

Activation of Platinum(IV) Prodrugs by Cytochrome c and Characterization of the Protein Binding Sites.

scientific article published on 9 August 2016

Activation of trans geometry in bifunctional mononuclear platinum complexes by a non-bulky methylamine ligand.

scientific article published on 28 May 2013

Activation of trans geometry in bifunctional mononuclear platinum complexes by a piperidine ligand. Mechanistic studies on antitumor action.

scientific article published on 10 September 2003

Adjusting the DNA Interaction and Anticancer Activity of Pt(II) N-Heterocyclic Carbene Complexes by Steric Shielding of the Trans Leaving Group

scientific article published on 16 July 2015

Adsorption of bacteriophage on bacterial surface and on the surface of Hg dropping electrode

scientific article published on 01 January 1967

Adsorption of human beta 2-microglobulin at a water/mercury interface

scientific article published on 01 April 1988

Adsorption of single-stranded and double-helical polynucleotides on the mercury electrode

scientific article published on 01 January 1972

Amide-based prodrugs of spermidine-bridged dinuclear platinum. Synthesis, DNA binding, and biological activity.

scientific article

An Anticancer PtIV Prodrug That Acts by Mechanisms Involving DNA Damage and Different Epigenetic Effects

scientific article published on 18 March 2019

An anticancer Os(II) bathophenanthroline complex as a human breast cancer stem cell-selective, mammosphere potent agent that kills cells by necroptosis

scientific article published on 16 September 2019

An electrochemical analysis of changes in properties of DNA caused by ionizing and ultraviolet radiations

scientific article published on 01 February 1980

Anticancer kiteplatin pyrophosphate derivatives show unexpected target selectivity for DNA.

scientific article

Anticancer potential of a photoactivated transplatin derivative containing the methylazaindole ligand mediated by ROS generation and DNA cleavage.

scientific article published on 11 July 2016

Antitumor bifunctional dinuclear Pt(II) complex BBR3535 forms interduplex DNA cross-links under molecular crowding conditions

scientific article published on 21 September 2011

Antitumor carboplatin is more toxic in tumor cells when photoactivated: enhanced DNA binding.

scientific article

Antitumor platinum(IV) derivatives of oxaliplatin with axial valproato ligands.

scientific article

Antitumoral effects of mitochondria-targeting neutral and cationic cis-[bis(1,3-dibenzylimidazol-2-ylidene)Cl(L)]Pt(ii) complexes

scientific article published on 19 June 2020

Assessment of DNA-binding affinity of cholinesterase reactivators and electrophoretic determination of their effect on topoisomerase I and II activity.

scientific article published on 14 July 2016

Bifunctional Amine-Tethered Ruthenium(II) Arene Complexes Form Monofunctional Adducts on DNA

scientific article published on 13 September 2007

Biochemical studies of the thermal effects on DNA modifications by the antitumor cisplatin and their repair

scientific article published on 01 November 2007

Biophysical analysis of DNA modified by 1,2-diaminocyclohexane platinum(II) complexes ⬇️

scientific article published on January 25, 1992

Biophysical studies of the complexes of polyriboguanylic acid with brominated and chlorinated polyribocytidylic acids

scientific article published on 01 July 1991

Biophysical studies on the stability of DNA intrastrand cross-links of transplatin.

scientific article published in August 2008

Bipyrimidine ruthenium(II) arene complexes: structure, reactivity and cytotoxicity.

scientific article

Cationic nonsymmetric transplatinum complexes with piperidinopiperidine ligands. Preparation, characterization, in vitro cytotoxicity, in vivo toxicity, and anticancer efficacy studies.

scientific article published on July 2006

Cellular response to antitumor cis-Dichlorido platinum(II) complexes of CDK inhibitor Bohemine and its analogues.

scientific article published on February 2012

Chiral discrimination in platinum anticancer drugs.

scientific article

Combined theoretical and computational study of interstrand DNA guanine-guanine cross-linking by trans-[Pt(pyridine)2] derived from the photoactivated prodrug trans,trans,trans-[Pt(N3)2(OH)2(pyridine)2]

scientific article published on 05 June 2012

Comment on "Delivering a photosensitive transplatin prodrug to overcome cisplatin drug resistance" by H. Song, W. Li, R. Qi, L. Yan, X. Jing, M. Zheng and H. Xiao, Chem. Commun., 2015, 51, 11493.

scientific article

Conformation and recognition of DNA damaged by antitumor cis-dichlorido platinum(II) complex of CDK inhibitor bohemine.

scientific article

Conformation and recognition of DNA modified by a new antitumor dinuclear PtII complex resistant to decomposition by sulfur nucleophiles.

scientific article

Conformation of DNA GG intrastrand cross-link of antitumor oxaliplatin and its enantiomeric analog.

scientific article published on 17 August 2007

Conformation of DNA modified by monofunctional Ru(II) arene complexes: recognition by DNA binding proteins and repair. Relationship to cytotoxicity.

scientific article published in January 2005

Conformation, recognition by high mobility group domain proteins, and nucleotide excision repair of DNA intrastrand cross-links of novel antitumor trinuclear platinum complex BBR3464

scientific article published on 12 April 2001

Conversion of DNA adducts of antitumour cis-diamminedichloroplatinum(II). Immunochemical analysis.

scientific article

Copper(ii) complexes with tridentate Schiff base-like ligands: solid state and solution structures and anticancer activity

scientific article published on 01 October 2019

Correlation between cytotoxicity and DNA binding of polypyridyl ruthenium complexes

scientific article published on 01 September 1995

Cytotoxicity, cellular uptake, and DNA interactions of new monodentate ruthenium(II) complexes containing terphenyl arenes.

scientific article

Cytotoxicity, cellular uptake, glutathione and DNA interactions of an antitumor large-ring Pt II chelate complex incorporating the cis-1,4-diaminocyclohexane carrier ligand.

scientific article published on February 2010

Cytotoxicity, mutagenicity, cellular uptake, DNA and glutathione interactions of lipophilic trans-platinum complexes tethered to 1-adamantylamine.

scientific article published on 25 December 2007

DNA Interactions of Monofunctional Organometallic Ruthenium(II) Antitumor Complexes in Cell-free Media ⬇️

scientific article published on October 7, 2003

DNA adducts of the enantiomers of the Pt(II) complexes of the ahaz ligand (ahaz=3-aminohexahydroazepine) and recognition of these adducts by HMG domain proteins.

scientific article

DNA and glutathione interactions in cell-free media of asymmetric platinum(II) complexes cis- and trans-[PtCl2(isopropylamine)(1-methylimidazole)]: relations to their different antitumor effects.

scientific article

DNA binding mode of ruthenium complexes and relationship to tumor cell toxicity.

scientific article published on 21 June 2006

DNA binding of dinuclear iron(II) metallosupramolecular cylinders. DNA unwinding and sequence preference

scientific article published on 8 May 2008

DNA condensing effects and sequence selectivity of DNA binding of antitumor noncovalent polynuclear platinum complexes.

scientific article published on 16 January 2014

DNA conformation and repair of polymeric natural DNA damaged by antitumor azolato-bridged dinuclear Pt(II) complex.

scientific article published on 4 May 2012

DNA conformational change produced by the site-specific interstrand cross-link of trans-diamminedichloroplatinum(II)

scientific article published on 01 November 1993

DNA interactions of 2-pyrrolinodoxorubicin, a distinctively more potent daunosamine-modified analogue of doxorubicin

scientific article published on 13 May 2011

DNA interactions of antitumor cisplatin analogs containing enantiomeric amine ligands.

scientific article

DNA interactions of antitumor platinum(IV) complexes

scientific article published on 01 March 1995

DNA interactions of antitumor trans-[PtCl2(NH3)(quinoline)].

scientific article

DNA interactions of bifunctional dinuclear platinum(II) antitumor agents

scientific article published on 01 June 1997

DNA interactions of cisplatin tethered to the DNA minor groove binder distamycin

scientific article published on 01 December 1999

DNA interactions of dinuclear RuII arene antitumor complexes in cell-free media

scientific article published on 28 October 2008

DNA interactions of new antitumor aminophosphine platinum(II) complexes

scientific article published on 01 July 1999

DNA interactions of new antitumor platinum complexes with trans geometry activated by a 2-metylbutylamine or sec-butylamine ligand.

scientific article published in March 2004

DNA interstrand cross-links of an antitumor trinuclear platinum(II) complex: thermodynamic analysis and chemical probing.

scientific article

DNA modifications by a novel bifunctional trinuclear platinum phase I anticancer agent

scientific article published on 01 May 1999

DNA modifications by antitumor platinum and ruthenium compounds: their recognition and repair.

scientific article

DNA modified by platinum derivatives cannot adopt the A-form

scientific article published on 01 May 1986

DNA-protein cross-linking by trans-[PtCl2(E-iminoether)2]. A concept for activation of the trans geometry in platinum antitumor complexes ⬇️

scientific article published on November 15, 2003

Deoxyribonuclease I footprinting reveals different DNA binding modes of bifunctional platinum complexes

scientific article published on 05 July 2006

Design, Preparation, and Characterization of Zn and Cu Metallopeptides Based On Tetradentate Aminopyridine Ligands Showing Enhanced DNA Cleavage Activity.

scientific article published on 27 October 2015

Determination of platinum in urine by differential pulse polarography

scientific article published on 01 April 1983

Diazido mixed-amine platinum(IV) anticancer complexes activatable by visible-light form novel DNA adducts.

scientific article published on 03 June 2013

Differences in the cellular response and signaling pathways between cisplatin and monodentate organometallic Ru(II) antitumor complexes containing a terphenyl ligand.

scientific article published on 19 April 2011

Different affinity of nuclear factor-kappa B proteins to DNA modified by antitumor cisplatin and its clinically ineffective trans isomer.

scientific article published on 23 January 2014

Different features of the DNA binding mode of antitumor cis-amminedichlorido(cyclohexylamine)platinum(II) (JM118) and cisplatin in vitro.

scientific article published on 12 October 2010

Different recognition of DNA modified by aatitumor cisplatin and its clinically ineffective trans isomer by tumor suppressor protein p53.

scientific article published on 06 March 2001

Differential recognition by the tumor suppressor protein p53 of DNA modified by the novel antitumor trinuclear platinum drug BBR3464 and cisplatin.

scientific article published on 14 October 2004

Discovery of selective, antimetastatic and anti-cancer stem cell metallohelices via post-assembly modification

scientific article published on 18 July 2019

Dual Triggering of DNA Binding and Fluorescence via Photoactivation of a Dinuclear Ruthenium(II) Arene Complex

scientific article published on 12 May 2007

Effect of sulfonamidoethylenediamine substituents in RuII arene anticancer catalysts on transfer hydrogenation of coenzyme NAD+ by formate.

scientific article published on 13 April 2018

Effect of the geometry of the central coordination sphere in antitumor trinuclear platinum complexes on DNA binding.

scientific article published in October 2004

Effects of antitumor derivatives of ineffective transplatin on bacterial cells: Is DNA a pharmacological target?

scientific article published on 20 July 2015

Effects of cytotoxic cis- and trans-diammine monochlorido platinum(II) complexes on selenium-dependent redox enzymes and DNA.

scientific article published on 26 October 2017

Effects of histidin-2-ylidene vs. imidazol-2-ylidene ligands on the anticancer and antivascular activity of complexes of ruthenium, iridium, platinum, and gold

scientific article

Electrochemical approach to the mechanism of urea denaturation of horse heart cytochrome c

scientific article published on 01 March 1983

Electrochemical reactions of horse heart cytochrome c at graphite electrodes

scientific article published on 01 August 1982

Energetics, conformation, and recognition of DNA duplexes containing a major adduct of an anticancer azolato-bridged dinuclear Pt(II) complex

scientific article published on 07 June 2012

Enhancing Tumor Cell Response to Chemotherapy through the Targeted Delivery of Platinum Drugs Mediated by Highly Stable, Multifunctional Carboxymethylcellulose-Coated Magnetic Nanoparticles.

scientific article

Epigenetic and antitumor effects of platinum(IV)-octanoato conjugates

scientific article

Exploring the Effect of the Polypyridyl Ligands on Anticancer Activity of Phosphorescent Iridium(III) Complexes: From Proteosynthesis Inhibitors to Photodynamic Therapy Agents

scientific article published on 25 January 2018

Ferrocenyl-Coupled N-Heterocyclic Carbene Complexes of Gold(I): A Successful Approach to Multinuclear Anticancer Drugs.

scientific article published on 20 October 2016

Formation of platinated GG cross-links on DNA by photoactivation of a platinum(IV) azide complex ⬇️

scientific article published on July 9, 2003

Functionalization of osmium arene anticancer complexes with (poly)arginine: effect on cellular uptake, internalization, and cytotoxicity

scientific article published on 27 January 2011

Gallium(III) Complex with Cloxyquin Ligands Induces Ferroptosis in Cancer Cells and Is a Potent Agent against Both Differentiated and Tumorigenic Cancer Stem Rhabdomyosarcoma Cells

scientific article published on 23 April 2022

Half-sandwich Os(ii) and Ru(ii) bathophenanthroline complexes: anticancer drug candidates with unusual potency and a cellular activity profile in highly invasive triple-negative breast cancer cells

scientific article published on 01 September 2018

High-throughput screening identifies novel agents eliciting hypersensitivity in Fanconi pathway-deficient cancer cells

scientific article published on 01 March 2007

Highly potent extranuclear-targeted luminescent iridium(iii) antitumor agents containing benzimidazole-based ligands with a handle for functionalization

scientific article

How to modify 7-azaindole to form cytotoxic Pt(II) complexes: highly in vitro anticancer effective cisplatin derivatives involving halogeno-substituted 7-azaindole.

scientific article published on 24 May 2012

Influence of pyridine versus piperidine ligands on the chemical, DNA binding and cytotoxic properties of light activated trans,trans,trans-[Pt(N3)2(OH)2(NH3)(L)] ⬇️

scientific article published on January 21, 2011

Influence of the binding of reduced NAMI-A to human serum albumin on the pharmacokinetics and biological activity.

scientific article

Inhibition of DNA topoisomerases I and II and growth inhibition of HL-60 cells by novel acridine-based compounds.

scientific article published on 8 May 2015

Inhibition of nuclear factor kappaB proteins-platinated DNA interactions correlates with cytotoxic effectiveness of the platinum complexes.

scientific article published on 30 August 2016

Insight into the toxic effects of cis-dichloridoplatinum(II) complexes containing 7-azaindole halogeno derivatives in tumor cells.

scientific article published on 15 May 2013

Interaction of dinuclear ruthenium(II) supramolecular cylinders with DNA: sequence-specific binding, unwinding, and photocleavage.

scientific article

Interaction of nucleic acids with electrically charged surfaces. VI. A comparative study on the electrochemical behaviour of native and denatured DNAs at graphite electrodes

scientific article published on May 1, 1979

Interaction of nucleic acids with electrically charged surfaces. VII. The effect of ionic strength of neutral medium on the conformation of dna adsorbed on the mercury electrode

scientific article published on 01 February 1980

Interactions of DNA with a new platinum(IV) azide dipyridine complex activated by UVA and visible light: relationship to toxicity in tumor cells.

scientific article

Interactions of platinum complexes containing cationic, bicyclic, nonplanar piperidinopiperidine ligands with biological nucleophiles

scientific article published on 01 July 2006

Interferon inducer, polyriboguanylic.polyribocytidylic acid, inhibits experimental hepatic metastases in mice

scientific article published on 01 October 1992

Internalization of Ineffective Platinum Complex in Nanocapsules Renders It Cytotoxic.

scientific article published on 20 January 2016

Iron(II) supramolecular helicates condense plasmid DNA and inhibit vital DNA-related enzymatic activities.

scientific article

Iron(II) supramolecular helicates interfere with the HIV-1 Tat-TAR RNA interaction critical for viral replication.

scientific article published on 12 July 2016

L-methionine inhibits reaction of DNA with anticancer cis-diamminedichloroplatinum(II).

scientific article

Lichen secondary metabolites as DNA-interacting agents.

scientific article published on 20 November 2013

Mechanism of cellular accumulation of an iridium(III) pentamethylcyclopentadienyl anticancer complex containing a C,N-chelating ligand.

scientific article published on 21 January 2014

Melting of cross-linked DNA v. cross-linking effect caused by local stabilization of the double helix

scientific article published on 01 February 2003

Metallohelices that kill Gram-negative pathogens using intracellular antimicrobial peptide pathways

scientific article published on 05 September 2019

Metallohelix vectors for efficient gene delivery via cationic DNA nanoparticles

scientific article published in 2022

Modification of natural, double-helical DNA by antitumor cis- and trans-[Cl(2)(Me(2)SO(4))(4)Ru] in cell-free media

scientific article published on 01 December 2000

Modifications of DNA by platinum complexes. Relation to resistance of tumors to platinum antitumor drugs.

scientific article

Molecular aspects of antitumor effects of a new platinum(IV) drug.

scientific article published on 8 August 2006

Molecular aspects of resistance to antitumor platinum drugs.

scientific article

Monofunctional adducts of platinum(II) produce in DNA a sequence-dependent local denaturation

scientific article published on 01 February 1994

Monofunctional and Interstrand DNA Adducts of Platinum(II) Complexes.

scientific article published in January 1994

Multiply Intercalator-Substituted Cu(II) Cyclen Complexes as DNA Condensers and DNA/RNA Synthesis Inhibitors.

scientific article published on 23 April 2018

N,N-Dialkylbenzimidazol-2-ylidene platinum complexes - effects of alkyl residues and ancillary cis-ligands on anticancer activity

scientific article published on 27 November 2018

NMR analysis of duplex d(CGCGATCGCG)2 modified by Lambda- and Delta-[Ru(bpy)2(m-GHK)]Cl2 and DNA photocleavage study

scientific article published on 07 November 2006

NMR analysis of duplex d(CGCGATCGCG)2 modified by Λ- and Δ-[Ru(bpy)2(m-GHK)]Cl2 and DNA photocleavage study.

scientific article published in March 2007

New (arene)ruthenium(II) complexes of 4‑aryl‑4H‑naphthopyrans with anticancer and anti-vascular activities.

scientific article published on 5 April 2018

New Acridine Thiourea Gold(I) Anticancer Agents: Targeting the Nucleus and Inhibiting Vasculogenic Mimicry.

scientific article

New half-sandwich ruthenium(ii) complexes as proteosynthesis inhibitors in cancer cells

scientific article published on 11 January 2019

New insights into the molecular and epigenetic effects of antitumor Pt(IV)-valproic acid conjugates in human ovarian cancer cells.

scientific article

New spiro tria(thia)zolidine-acridines as topoisomerase inhibitors, DNA binders and cytostatic compounds

scientific article published on 6 February 2016

Novel Antitumor Cisplatin and Transplatin Derivatives Containing 1-Methyl-7-Azaindole: Synthesis, Characterization, and Cellular Responses

article

Novel Antitumor Platinum(II) Conjugates Containing the Nonsteroidal Anti-inflammatory Agent Diclofenac: Synthesis and Dual Mechanisms of Antiproliferative Effects.

scientific article published on 19 January 2017

Novel cis-Pt(II) Complexes with Alkylpyrazole Ligands: Synthesis, Characterization, and Unusual Mode of Anticancer Action

scientific article published on 02 March 2022

Novel trisubstituted acridines as human telomeric quadruplex binding ligands.

scientific article published on 10 August 2014

Optically Pure Metallohelices That Accumulate in Cell Nuclei, Condense/Aggregate DNA, and Inhibit Activities of DNA Processing Enzymes

scientific article published on 17 February 2020

Organometallic half-sandwich iridium anticancer complexes.

scientific article published on 28 March 2011

Organoruthenium Complexes with C^N Ligands are Highly Potent Cytotoxic Agents that Act by a New Mechanism of Action.

scientific article published on 18 September 2017

Photo-induced DNA cleavage and cytotoxicity of a ruthenium(II) arene anticancer complex.

scientific article published on 30 December 2015

Photoactivatable Cell-Selective Dinuclear trans-Diazidoplatinum(IV) Anticancer Prodrugs

scientific article published on 26 October 2018

Platinum (IV) Derivatives with Cinnamate Axial Ligands as Potent Agents Against Both Differentiated and Tumorigenic Cancer Stem Rhabdomyosarcoma Cells

scientific article published on 07 January 2020

Platinum determination in cis-dichlorodiammineplatinum(II)--DNA complexes by differential pulse polarography

scientific article published on 01 October 1984

Platinum(IV)-Estramustine Multiaction Prodrugs Are Effective Antiproliferative Agents against Prostate Cancer Cells

scientific article published on 11 November 2020

Platinum-DNA interstrand crosslinks: molecular determinants of bending and unwinding of the double helix

scientific article published on 22 September 2011

Polarographic activity of the antitumor drug cis-dichlorodiammineplatinum (II). The effect of hydrolysis and trans-isomerization of the drug

scientific article published on 01 May 1984

Polynuclear Platinum Complexes. Structural Diversity and DNA Binding

scientific article published in February 2018

Potential and structure controlled interfacial behavior of uracil derivatives

scientific article published on 01 January 1978

Potentiation of mitochondrial dysfunction in tumor cells by conjugates of metabolic modulator dichloroacetate with a Pt(IV) derivative of oxaliplatin.

scientific article published on 31 December 2015

Pt(iv) derivatives of cisplatin and oxaliplatin with phenylbutyrate axial ligands are potent cytotoxic agents that act by several mechanisms of action

scientific article published on 15 January 2016

Raman scattering from nucleic acids adsorbed at a silver electrode

Raman spectroscopy of DNA modified by intrastrand cross-links of antitumor cisplatin

scientific article published on 23 January 2007

Reaction of Zn7Metallothionein withcis- andtrans-[Pt(N-donor)2Cl2] Anticancer Complexes: trans-PtIIComplexes Retain Their N-Donor Ligands

scientific article published on 01 August 2007

Recognition of DNA bulges by dinuclear iron(II) metallosupramolecular helicates

scientific article published on 13 January 2014

Recognition of DNA interstrand cross-link of antitumor cisplatin by HMGB1 protein.

scientific article

Recognition of DNA interstrand cross-links of cis-diamminedichloroplatinum(II) and its trans isomer by DNA-binding proteins

scientific article published on 01 September 1995

Recognition of DNA modified by antitumor cisplatin by “latent” and “active” protein p53 ⬇️

scientific article published on April 15, 2003

Recognition of DNA modified by trans-[PtClNH(4-hydroxymethylpyridine)] by tumor suppressor protein p53 and character of DNA adducts of this cytotoxic complex.

scientific article

Recognition of DNA/RNA bulges by antimicrobial and antitumor metallohelices.

scientific article published on 27 July 2015

Recognition of cisplatin-damaged DNA by p53 protein: critical role of the p53 C-terminal domain.

scientific article

Relation between differential pulse voltammetric oxidation of polyriboinosinic acid and its structure

scientific article published on 01 April 1981

Restriction-enzyme cleavage of DNA modified by platinum(II) complexes

scientific article published on 01 August 1993

Sequence-dependent distortions induced in DNA by monofunctional platinum(II) binding

scientific article published on December 15, 1992

Shape-selective recognition of DNA abasic sites by metallohelices: inhibition of human AP endonuclease 1.

scientific article published on 4 May 2015

Somatostatin receptor-targeted organometallic iridium(iii) complexes as novel theranostic agents

scientific article published on 3 May 2017

Spontaneous translocation of antitumor oxaliplatin, its enantiomeric analogue, and Cisplatin from one strand to another in double-helical DNA.

scientific article published on 19 July 2013

Studies of the mechanism of action of platinum(II) complexes with potent cytotoxicity in human cancer cells.

scientific article

Studies on Cellular Accumulation of Satraplatin and Its Major Metabolite JM118 and Their Interactions with Glutathione ⬇️

scientific article published on October 25, 2010

Study of thermal and acid denaturation of DNA by means of voltammetry at graphite electrodes

scientific article published on 01 October 1979

Substitution-Inert Polynuclear Platinum Complexes Act as Potent Inducers of Condensation/Aggregation of Short Single- and Double-Stranded DNA and RNA Oligonucleotides

scientific article published on 29 January 2019

Substitution-Inert Polynuclear Platinum Complexes Inhibit Reverse Transcription Preferentially in RNA Triplex-Forming Templates

scientific article published on 29 September 2020

Substitution-Inert Polynuclear Platinum Complexes That Inhibit the Activity of DNA Polymerase in Triplex-Forming Templates

scientific article published on 07 June 2018

Substitution-Inert Polynuclear Platinum Complexes with Dangling Amines: Condensation/Aggregation of Nucleic Acids and Inhibition of DNA-Related Enzymatic Activities

scientific article published on 02 May 2019

Substitution-inert trinuclear platinum complexes efficiently condense/aggregate nucleic acids and inhibit enzymatic activity

scientific article published on 24 September 2014

Superhelical torsion controls DNA interstrand cross-linking by antitumor cis- diamminedichloroplatinum(II)

scientific article published on October 1996

Synthesis, antiproliferative activity in cancer cells and DNA interaction studies of [Pt(cis-1,3-diaminocycloalkane)Cl2] analogs

scientific article published on 26 August 2020

Synthesis, biophysical studies, and antiproliferative activity of platinum(II) complexes having 1,2-bis(aminomethyl)carbobicyclic ligands.

scientific article

Synthesis, characterization and biological evaluation of Co(III) complexes with quinolone drugs

scientific article published on 21 January 2019

Tacrine derivatives as dual topoisomerase I and II catalytic inhibitors.

scientific article

Temperature dependence of the interfacial behavior of uracil derivatives ⬇️

scientific article published on May 1, 1978

The contrasting chemistry and cancer cell cytotoxicity of bipyridine and bipyridinediol ruthenium(II) arene complexes.

scientific article

The effect of combined treatment with platinum complexes and ionizing radiation on DNA in vitro.

scientific article published on December 1986

The effect of ionic strength on melting of DNA modified by platinum(II) complexes

scientific article published on 01 June 1996

The effect of platinum derivatives on interfacial properties of DNA

scientific article published on 01 December 1987

The induction of lysis in lysogenic strains of Escherichia coli by a new antitumor transplatin derivative and its DNA interactions

scientific article

The influence of salts andpH on polarographic currents produced by denatured DNA ⬇️

scientific article

The realtion between the polarographic behaviour of DNA and its conformation in solution

scientific article published on 01 March 1972

The stability of DNA intrastrand cross-links of antitumor transplatin derivative containing non-bulky methylamine ligands

scientific article published on 02 July 2014

Thermal and thermodynamic properties of duplex DNA containing site-specific interstrand cross-link of antitumor cisplatin or its clinically ineffective trans isomer

scientific article published on 04 December 2000

Thermal stability and energetics of 15-mer DNA duplex interstrand crosslinked by trans-diamminedichloroplatinum(II)

scientific article published on 01 March 2005

Thermodynamic Insights by Microscale Thermophoresis into Translesion DNA Synthesis Catalyzed by DNA Polymerases Across a Lesion of Antitumor Platinum-Acridine Complex

scientific article published on 21 October 2020

Thermodynamic and mechanistic insights into translesion DNA synthesis catalyzed by Y-family DNA polymerase across a bulky double-base lesion of an antitumor platinum drug.

scientific article

Thermodynamic impact of abasic sites on simulated translesion DNA synthesis

scientific article published on 26 May 2014

Thermodynamic properties of damaged DNA and its recognition by xeroderma pigmentosum group A protein and replication protein A.

scientific article published on 22 December 2005

Thermodynamic stability and energetics of DNA duplexes containing major intrastrand cross-links of second-generation antitumor dinuclear Pt(II) complexes

scientific article published on 06 September 2011

Thermodynamics of translesion synthesis across a major DNA adduct of antitumor oxaliplatin: differential scanning calorimetric study.

scientific article published on 30 December 2011

Towards Novel Photodynamic Anticancer Agents Generating Superoxide Anion Radicals: A Cyclometalated IrIII Complex Conjugated to a Far-Red Emitting Coumarin

scientific article published on 04 April 2019

Trans-diamminedichlorplatinum (II)-modified probes for detection of picogram quantities of DNA

scientific article published on October 1, 1992

Transfer Hydrogenation and Antiproliferative Activity of Tethered Half-Sandwich Organoruthenium Catalysts.

scientific article

Translesion DNA Synthesis Across Lesions Induced by Oxidative Products of Pyrimidines: An Insight into the Mechanism by Microscale Thermophoresis

scientific article published on 10 October 2019

Translesion DNA synthesis across double-base lesions derived from cross-links of an antitumor trinuclear platinum compound: primer extension, conformational and thermodynamic studies.

scientific article published on 15 December 2017

Transplatin is cytotoxic when photoactivated: enhanced formation of DNA cross-links

scientific article published on 01 December 2006

Triazole-based, optically-pure metallosupramolecules; highly potent and selective anticancer compounds

scientific article published on 11 May 2020

Trifunctional dinuclear platinum complexes as DNA-protein cross-linking agents.

scientific article

Unique DNA binding mode of antitumor trinuclear tridentate platinum(II) compound

scientific article published on 16 November 2011

Unique properties of DNA interstrand cross-links of antitumor oxaliplatin and the effect of chirality of the carrier ligand.

scientific article published in January 2008

Unique structural properties of DNA interstrand cross-links formed by a new antitumor dinuclear Pt(ii) complex

scientific article published on 24 April 2017

Valuable insight into the anticancer activity of the platinum-histone deacetylase inhibitor conjugate, cis-[Pt(NH3)2malSAHA-2H)].

scientific article published on 25 May 2012

Walking of antitumor bifunctional trinuclear PtII complex on double-helical DNA.

scientific article

cis-Pt I2(NH3)2: a reappraisal

scientific article published on 30 July 2015

Paulina is supported by:

About Paulina

Help