Search filters

List of works by Anna Chiarini

Amyloid β-Exposed Human Astrocytes Overproduce Phospho-Tau and Overrelease It within Exosomes, Effects Suppressed by Calcilytic NPS 2143-Further Implications for Alzheimer's Therapy

scientific article published on 20 April 2017

Amyloid-β(25-35), an amyloid-β(1-42) surrogate, and proinflammatory cytokines stimulate VEGF-A secretion by cultured, early passage, normoxic adult human cerebral astrocytes.

scientific article published in January 2010

Antagonizing amyloid-β/calcium-sensing receptor signaling in human astrocytes and neurons: a key to halt Alzheimer's disease progression?

scientific article

BH(4) (tetrahydrobiopterin)-dependent activation, but not the expression, of inducible NOS (nitric oxide synthase)-2 in proinflammatory cytokine-stimulated, cultured normal human astrocytes is mediated by MEK-ERK kinases

scientific article published in March 2005

Bcl10 crucially nucleates the pro-apoptotic complexes comprising PDK1, PKCζ and caspase-3 at the nuclear envelope of etoposide-treated human cervical carcinoma C4-I cells.

scientific article published on 20 July 2015

Biocompatible Silk Noil-Based Three-Dimensional Carded-Needled Nonwoven Scaffolds Guide the Engineering of Novel Skin Connective Tissue.

scientific article published on 13 July 2016

Calcium-Sensing Receptor Antagonist NPS 2143 Restores Amyloid Precursor Protein Physiological Non-Amyloidogenic Processing in Aβ-Exposed Adult Human Astrocytes.

scientific article published on 28 April 2017

Calcium-Sensing Receptors of Human Neural Cells Play Crucial Roles in Alzheimer's Disease

scientific article

Calcium-sensing receptor (CaSR) in human brain's pathophysiology: roles in late-onset Alzheimer's disease (LOAD).

scientific article published on April 2009

Calcium-sensing receptor antagonist (calcilytic) NPS 2143 specifically blocks the increased secretion of endogenous Aβ42 prompted by exogenous fibrillary or soluble Aβ25-35 in human cortical astrocytes and neurons-therapeutic relevance to Alzheimer'

scientific article published on 26 April 2013

Changes in nuclear protein kinase C-delta holoenzyme, its catalytic fragments, and its activity in polyomavirus-transformed pyF111 rat fibroblasts while proliferating and following exposure to apoptogenic topoisomerase-II inhibitors.

scientific article published in May 1999

Combining immunofluorescence with in situ proximity ligation assay: a novel imaging approach to monitor protein-protein interactions in relation to subcellular localization

scientific article

Cytosolic sialidase from pig brain: a 'protein complex' containing catalytic and protective units

scientific article published on 01 October 1994

De novo engineering of reticular connective tissue in vivo by silk fibroin nonwoven materials.

scientific article published in May 2005

Direct screening of herbal blends for new synthetic cannabinoids by MALDI-TOF MS.

scientific article

Do astrocytes collaborate with neurons in spreading the "infectious" aβ and Tau drivers of Alzheimer's disease?

scientific article published on 16 April 2014

Electrospun Silk Fibroin Scaffolds for Tissue Regeneration: Chemical, Structural, and Toxicological Implications of the Formic Acid-Silk Fibroin Interaction

scientific article published on 27 January 2022

Evidence for caspase-dependent programmed cell death along with repair processes in affected skeletal muscle fibres in patients with mitochondrial disorders

scientific article published on 2 November 2015

Exosomes of adult human fibroblasts cultured on 3D silk fibroin nonwovens intensely stimulate neoangiogenesis

scientific article published on 04 May 2021

Human erythrocyte sialidase is linked to the plasma membrane by a glycosylphosphatidylinositol anchor and partly located on the outer surface.

scientific article

Increased Calcium-Sensing Receptor Immunoreactivity in the Hippocampus of a Triple Transgenic Mouse Model of Alzheimer's Disease.

scientific article published on 16 February 2017

Increased activity of the protein kinase C-delta holoenzyme in the cytoplasmic particulate fraction precedes the activation of caspases in polyomavirus-transformed pyF111 rat fibroblasts exposed to calphostin C or topoisomerase-II inhibitors.

scientific article

Photoexcited calphostin C selectively destroys nuclear lamin B1 in neoplastic human and rat cells - a novel mechanism of action of a photodynamic tumor therapy agent.

scientific article

Preventing the spread of Alzheimer's disease neuropathology: a role for calcilytics?

scientific article published on January 2015

Protein kinase C-beta II Is an apoptotic lamin kinase in polyomavirus-transformed, etoposide-treated pyF111 rat fibroblasts

scientific article published on 18 March 2002

Role-shifting PKCζ fosters its own proapoptotic destruction by complexing with Bcl10 at the nuclear envelope of human cervical carcinoma cells: a proteomic and biochemical study.

scientific article

Solubilization of the membrane-bound sialidase from pig brain by treatment with bacterial phosphatidylinositol phospholipase C.

scientific article published in November 1990

Targeting Human Astrocytes' Calcium-sensing Receptors for Treatment of Alzheimer's Disease

scientific article published on 10 July 2017

The Amyloid-β42 Proxy, Amyloid-β25-35, Induces Normal Human Cerebral Astrocytes to Produce Amyloid-β42

scientific article published on 01 January 2011

The Aβ peptides-activated calcium-sensing receptor stimulates the production and secretion of vascular endothelial growth factor-A by normoxic adult human cortical astrocytes.

scientific article published on 20 June 2014

The calcium-sensing receptor: a novel Alzheimer's disease crucial target?

scientific article published on 28 July 2012

The p75 neurotrophin receptor is localized to primary cilia in adult murine hippocampal dentate gyrus granule cells

scientific article published on 25 September 2010