List of works by Michael Hecker

A genetic variant associated with multiple sclerosis inversely affects the expression of CD58 and microRNA-548ac from the same gene

article

Aberrant expression of alternative splicing variants in multiple sclerosis - A systematic review

scientific article published on 04 May 2019

Adherence to Long-Term Interferon Beta-1b Injection Therapy in Patients with Multiple Sclerosis Using an Electronic Diary.

scientific article published on 18 April 2016

An inventory of short term and long term changes in gene expression under interferon β treatment of relapsing remitting MS patients.

scientific article published on January 2012

Analysis of microRNA and Gene Expression Profiles in Multiple Sclerosis: Integrating Interaction Data to Uncover Regulatory Mechanisms.

scientific article

Association of smoking but not HLA-DRB1*15:01, APOE or body mass index with brain atrophy in early multiple sclerosis.

scientific article published in March 2018

Baseline predictors of persistence to first disease-modifying treatment in multiple sclerosis

scientific article published on 30 October 2016

Blood transcriptome profiling captures dysregulated pathways and response to treatment in neuroimmunological disease

scientific article published on 24 October 2019

Comparative evaluation of patients' and physicians' satisfaction with interferon beta-1b therapy

scientific article

Computational analysis of high-density peptide microarray data with application from systemic sclerosis to multiple sclerosis

scientific article

Deregulation of microRNA-181c in cerebrospinal fluid of patients with clinically isolated syndrome is associated with early conversion to relapsing-remitting multiple sclerosis.

scientific article published on 22 October 2015

Dysregulation of Inflammasome Priming and Activation by MicroRNAs in Human Immune-Mediated Diseases

scientific article published on 01 April 2019

Epitope predictions indicate the presence of two distinct types of epitope-antibody-reactivities determined by epitope profiling of intravenous immunoglobulins

scientific article published on 11 November 2013

Fingolimod alters the transcriptome profile of circulating CD4+ cells in multiple sclerosis.

scientific article published on 03 February 2017

Fluorescent-increase kinetics of different fluorescent reporters used for qPCR depend on monitoring chemistry, targeted sequence, type of DNA input and PCR efficiency.

scientific article published on 14 January 2014

Frequencies of polymorphisms in cytokines, neurotransmitters and adrenergic receptors in patients with complex regional pain syndrome type I after distal radial fracture.

scientific article published in March 2010

Gene regulatory network inference: data integration in dynamic models-a review

scientific article

Glatiramer acetate treatment effects on gene expression in monocytes of multiple sclerosis patients.

scientific article published on 17 October 2013

High-Density Peptide Microarray Analysis of IgG Autoantibody Reactivities in Serum and Cerebrospinal Fluid of Multiple Sclerosis Patients.

scientific article published on February 2016

High-Resolution Expression Profiling of Peripheral Blood CD8+ Cells in Patients with Multiple Sclerosis Displays Fingolimod-Induced Immune Cell Redistribution.

scientific article published on 8 September 2016

Immunogenicity and predictors of response to a single dose trivalent seasonal influenza vaccine in multiple sclerosis patients receiving disease-modifying therapies

scientific article published on 25 July 2018

Implication of genetic variants in primary microRNA processing sites in the risk of multiple sclerosis

scientific article published on 10 May 2022

Integration of MicroRNA databases to study MicroRNAs associated with multiple sclerosis.

scientific article published on 2 May 2012

Integrative modeling of transcriptional regulation in response to antirheumatic therapy

scientific article published on 24 August 2009

Interferon beta-1a sc at 25 years: a mainstay in the treatment of multiple sclerosis over the period of one generation

scientific article published in 2023

Interferon β-1a and β-1b for patients with multiple sclerosis: updates to current knowledge.

scientific article published on 10 January 2018

Interferon-beta therapy in multiple sclerosis: the short-term and long-term effects on the patients' individual gene expression in peripheral blood

scientific article published in May 2013

Intravenous immunoglobulin treatment in multiple sclerosis: A prospective, rater-blinded analysis of relapse rates during pregnancy and the postnatal period

scientific article published on 01 June 2018

Mass spectrometric characterization of protein structure details refines the proteome signature for invasive ductal breast carcinoma.

scientific article

MicroRNA expression changes during interferon-beta treatment in the peripheral blood of multiple sclerosis patients

scientific article published on 05 August 2013

MicroRNAs in multiple sclerosis and experimental autoimmune encephalomyelitis.

scientific article published on 18 May 2011

Microarray data of transcriptome shifts in blood cell subsets during S1P receptor modulator therapy.

scientific article published on 24 July 2018

Molecular biomarkers in cerebrospinal fluid of multiple sclerosis patients.

scientific article published on 10 June 2015

Molecular discrimination of responders and nonresponders to anti-TNF alpha therapy in rheumatoid arthritis by etanercept

scientific article published on 2 May 2008

Monitoring of multiple sclerosis immunotherapy: from single candidates to biomarker networks.

scientific article published on December 2008

Multi-drug use among patients with multiple sclerosis: A cross-sectional study of associations to clinicodemographic factors

scientific article published on 06 March 2019

Multiple sclerosis: modulation of toll-like receptor (TLR) expression by interferon-β includes upregulation of TLR7 in plasmacytoid dendritic cells

scientific article

Network analysis of transcriptional regulation in response to intramuscular interferon-β-1a multiple sclerosis treatment.

scientific article published on 19 October 2010

Novel multiple sclerosis susceptibility loci implicated in epigenetic regulation

scientific article published on 17 June 2016

Polypharmacy among patients with multiple sclerosis: a qualitative systematic review

scientific article published on 27 January 2020

Polypharmacy in outpatients with relapsing-remitting multiple sclerosis: A single-center study

scientific article published in PLoS ONE

Polypharmacy in patients with multiple sclerosis: a gender-specific analysis

scientific article published on 27 May 2019

Reassessment of blood gene expression markers for the prognosis of relapsing-remitting multiple sclerosis

scientific article (publication date: 2011)

Sieving treatment biomarkers from blood gene-expression profiles: a pharmacogenomic update on two types of multiple sclerosis therapy.

scientific article published on March 2011

Successful Replication of GWAS Hits for Multiple Sclerosis in 10,000 Germans Using the Exome Array

scientific article published on 26 October 2015

Susceptibility variants in the CD58 gene locus point to a role of microRNA-548ac in the pathogenesis of multiple sclerosis.

scientific article published on 16 October 2014

TPP2 mutation associated with sterile brain inflammation mimicking MS

The Rare IL22RA2 Signal Peptide Coding Variant rs28385692 Decreases Secretion of IL-22BP Isoform-1, -2 and -3 and Is Associated with Risk for Multiple Sclerosis

scientific article published on 10 January 2020

Towards a proteome signature for invasive ductal breast carcinoma derived from label-free nanoscale LC-MS protein expression profiling of tumorous and glandular tissue

scientific article

Transcriptome profiling of peripheral blood immune cell populations in multiple sclerosis patients before and during treatment with a sphingosine-1-phosphate receptor modulator

scientific article published on 3 January 2018

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