List of works - Donna L. Farber

A biochemical signature for rapid recall of memory CD4 T cells.

scientific article published in September 2007

A peptide-major histocompatibility complex II chimera favors survival of pancreatic beta-islets grafted in type 1 diabetic mice

scientific article published in June 2008

Ablation of SLP-76 signaling after T cell priming generates memory CD4 T cells impaired in steady-state and cytokine-driven homeostasis.

scientific article

Airway CD8(+) T Cells Are Associated with Lung Injury during Infant Viral Respiratory Tract Infection.

scientific article

An AXL/LRP-1/RANBP9 complex mediates DC efferocytosis and antigen cross-presentation in vivo.

scientific article published on 10 February 2014

An atlas of B-cell clonal distribution in the human body.

scientific article published on 21 August 2017

Anti-CD3 priming generates heterogeneous antigen-specific memory CD4 T cells

scientific article published on 6 September 2005

Antibody responses to SARS-CoV2 are distinct in children with MIS-C compared to adults with COVID-19

scientific article published on 14 July 2020

Autoimmune odyssey on the Aegean Sea

scientific article published on 01 March 2006

Biased Generation and In Situ Activation of Lung Tissue-Resident Memory CD4 T Cells in the Pathogenesis of Allergic Asthma

scientific article published on 17 January 2018

Bordetella pertussis Infection Exacerbates Influenza Virus Infection through Pertussis Toxin-Mediated Suppression of Innate Immunity ⬇️

scientific article published on April 20, 2011

CD45 ligation expands Tregs by promoting interactions with DCs

scientific article

CTLA4 expression is an indicator and regulator of steady-state CD4+ FoxP3+ T cell homeostasis

scientific article published on August 2008

Committed to memory: lineage choices for activated T cells.

scientific article

Conditional PDK1 Ablation Promotes Epidermal and T-Cell-Mediated Dysfunctions Leading to Inflammatory Skin Disease

scientific article published on 22 June 2015

Control of adaptive immunity: from naïve to memory.

scientific article

Cross-tissue immune cell analysis reveals tissue-specific features in humans

scientific article published on 13 May 2022

Cutting edge: Tissue-retentive lung memory CD4 T cells mediate optimal protection to respiratory virus infection

scientific article published on 4 November 2011

Developmental Regulation of Effector and Resident Memory T Cell Generation during Pediatric Viral Respiratory Tract Infection

scientific article published on 30 May 2018

Differential SLP-76 expression and TCR-mediated signaling in effector and memory CD4 T cells

scientific article

Differential T cell receptor-mediated signaling in naive and memory CD4 T cells

scientific article published in August 1997

Dissecting lung development and fibrosis at single-cell resolution

article

Distinct antibody responses to SARS-CoV-2 in children and adults across the COVID-19 clinical spectrum

scientific article published on 05 November 2020

Distribution and Compartmentalization of Human Circulating and Tissue-Resident Memory T Cell Subsets ⬇️

scientific article published on December 20, 2012

Early-life compartmentalization of human T cell differentiation and regulatory function in mucosal and lymphoid tissues

scientific article

Emerging concepts in tissue-resident T cells: lessons from humans

scientific article

Endogenous expansion of regulatory T cells leads to long-term islet graft survival in diabetic NOD mice

scientific article published on 02 February 2012

Enhancing alloreactivity does not restore GVHD induction but augments skin graft rejection by CD4+ effector memory T cells ⬇️

scientific article published on August 18, 2011

Form and function for T cells in health and disease

scientific article published on 01 February 2020

Functional heterogeneity of human tissue-resident memory T cells based on dye efflux capacities.

scientific article published on 15 November 2018

Functional plasticity of an antigen-specific memory CD4 T cell population.

scientific article

Gene transfection and expression in resting and activated murine CD4 T cell subsets

scientific article published in November 2003

Generation and functional capacity of polyclonal alloantigen-specific memory CD4 T cells.

scientific article published in June 2006

Generation and persistence of human tissue-resident memory T cells in lung transplantation

scientific article published on 01 March 2019

Generation, homeostasis, and regulation of memory T cells in transplantation

scientific article published on February 2007

Generation, persistence and plasticity of CD4 T-cell memories.

scientific article published on 10 May 2010

Human Lymph Nodes Maintain TCF-1 Memory T Cells with High Functional Potential and Clonal Diversity throughout Life

scientific article published on 15 August 2018

Human T Cell Development, Localization, and Function throughout Life

scientific article published in February 2018

Human Tissue-Resident Memory T Cells Are Defined by Core Transcriptional and Functional Signatures in Lymphoid and Mucosal Sites

scientific article published on September 2017

Human immunology studies using organ donors: Impact of clinical variations on immune parameters in tissues and circulation.

scientific article

Human memory T cells: generation, compartmentalization and homeostasis

scientific article

Identification and Targeting of Costimulation-Resistant T cells in Renal Transplantation ⬇️

scientific article published on 01 January 2011

Immunological memory: lessons from the past and a look to the future

scientific article published in February 2016

Increased memory conversion of naïve CD8 T cells activated during late phases of acute virus infection due to decreased cumulative antigen exposure

scientific article

Innate lymphoid cells promote anatomical containment of lymphoid-resident commensal bacteria.

scientific article

Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus

scientific article published in November 2011

Isoforms of the transmembrane tyrosine phosphatase CD45 differentially affect T cell recognition.

scientific article published on May 1994

Location, location, location: Tissue resident memory T cells in mice and humans

scientific article published on 01 April 2019

Long-term Persistence of Innate Lymphoid Cells in the Gut After Intestinal Transplantation

scientific article published on 8 December 2016

Long-term islet graft survival in NOD mice by abrogation of recurrent autoimmunity

scientific article published on 01 September 2004

Lung niches for the generation and maintenance of tissue-resident memory T cells.

scientific article published on 25 September 2013

Macrochimerism in Intestinal Transplantation: Association With Lower Rejection Rates and Multivisceral Transplants, Without GVHD.

scientific article

Maintenance of the human memory T cell repertoire by subset and tissue site

scientific article published on 14 June 2021

Memory CD4 T cells direct protective responses to influenza virus in the lungs through helper-independent mechanisms.

scientific article

Memory CD4 T cells in influenza.

scientific article published on January 2015

Memory T cells in transplantation: generation, function, and potential role in rejection.

scientific article published on June 2004

Memory T-cell predominance following T-cell depletional therapy derives from homeostatic expansion of naive T cells

scientific article published on 22 September 2009

Microanatomical dissection of human intestinal T-cell immunity reveals site-specific changes in gut-associated lymphoid tissues over life

scientific article published on 06 December 2018

Modulation of the fungal mycobiome is regulated by the chitin-binding receptor FIBCD1

scientific article published on 10 October 2019

Molecular programs of fibrotic change in aging human lung

scientific article published on 02 November 2021

Mucosal resident memory CD4 T cells in protection and immunopathology

scientific article

NF-κB signaling participates in both RANKL- and IL-4-induced macrophage fusion: receptor cross-talk leads to alterations in NF-κB pathways.

scientific article

Novel phenotypes and migratory properties distinguish memory CD4 T cell subsets in lymphoid and lung tissue

scientific article published in November 2005

Novel signaling interactions between proteinase-activated receptor 2 and Toll-like receptors in vitro and in vivo

scientific article

Phenotypic alterations in pancreatic lymph node stromal cells from human donors with type 1 diabetes and NOD mice

scientific article published on 05 September 2019

Prolonged antigen presentation is required for optimal CD8+ T cell responses against malaria liver stage parasites

scientific article

Pulse-oximetry accurately predicts lung pathology and the immune response during influenza infection

scientific article published on 02 June 2009

Recalling the year in memory T cells.

scientific article

Reduced generation of lung tissue-resident memory T cells during infancy.

scientific article published on 30 August 2017

Remembrance of antigens past: new insights into memory T cells.

scientific article

Reshaping the past: Strategies for modulating T-cell memory immune responses.

scientific article published on 17 August 2006

SARS-CoV-2 infection generates tissue-localized immunological memory in humans

scientific article published on 19 November 2021

Single-cell transcriptomics of human T cells reveals tissue and activation signatures in health and disease

scientific article published on 17 October 2019

Spatial and Temporal Mapping of Human Innate Lymphoid Cells Reveals Elements of Tissue Specificity

scientific article published on 12 February 2019

Splenic priming of virus-specific CD8 T cells following influenza virus infection

scientific article published on 6 February 2013

TLR2 engagement on dendritic cells promotes high frequency effector and memory CD4 T cell responses.

scientific article published in December 2009

The MBP fusion protein restores the activity of the first phosphatase domain of CD45

scientific article published on 01 July 1997

The anti-tumor agent, 5,6-dimethylxanthenone-4-acetic acid (DMXAA), induces IFN-beta-mediated antiviral activity in vitro and in vivo

scientific article

The neonatal window of opportunity-early priming for life.

scientific article published on 13 December 2017

The neuropeptide neuromedin U stimulates innate lymphoid cells and type 2 inflammation.

scientific article

Thymic stromal lymphopoietin-mediated extramedullary hematopoiesis promotes allergic inflammation.

scientific article published on December 2013

Thymic-Peripheral Crosstalk in Lymphodepletion Therapy.

scientific article published on 19 June 2017

Tissue Determinants of Human NK Cell Development, Function, and Residence

scientific article published on 13 February 2020

Tissue compartmentalization of T cell responses during early life

scientific article published on 11 September 2017

Tissue reservoirs of antiviral T cell immunity in persistent human CMV infection.

scientific article published on 27 January 2017

Tissue-Resident Memory T Cells in Mice and Humans: Towards a Quantitative Ecology

scientific article published on 01 November 2019

Tissue-resident T cells, in situ immunity and transplantation.

scientific article published on March 2014

Training T cells for tissue residence

scientific article

Transcriptional Control of Rapid Recall by Memory CD4 T Cells ⬇️

scientific article published on June 3, 2011

Transcriptional activation of the human inducible nitric-oxide synthase promoter by Kruppel-like factor 6.

scientific article

Vaccine-based approaches to squamous cell carcinoma of the head and neck.

scientific article published on January 2007

Viral Bronchiolitis in Children

scientific article published in May 2016

List of works by Donna L. Farber

A biochemical signature for rapid recall of memory CD4 T cells.

A peptide-major histocompatibility complex II chimera favors survival of pancreatic beta-islets grafted in type 1 diabetic mice

Ablation of SLP-76 signaling after T cell priming generates memory CD4 T cells impaired in steady-state and cytokine-driven homeostasis.

Airway CD8(+) T Cells Are Associated with Lung Injury during Infant Viral Respiratory Tract Infection.

An AXL/LRP-1/RANBP9 complex mediates DC efferocytosis and antigen cross-presentation in vivo.

An atlas of B-cell clonal distribution in the human body.

Anti-CD3 priming generates heterogeneous antigen-specific memory CD4 T cells

Antibody responses to SARS-CoV2 are distinct in children with MIS-C compared to adults with COVID-19

Autoimmune odyssey on the Aegean Sea

Biased Generation and In Situ Activation of Lung Tissue-Resident Memory CD4 T Cells in the Pathogenesis of Allergic Asthma

Bordetella pertussis Infection Exacerbates Influenza Virus Infection through Pertussis Toxin-Mediated Suppression of Innate Immunity ⬇️

CD45 ligation expands Tregs by promoting interactions with DCs

CTLA4 expression is an indicator and regulator of steady-state CD4+ FoxP3+ T cell homeostasis

Committed to memory: lineage choices for activated T cells.

Conditional PDK1 Ablation Promotes Epidermal and T-Cell-Mediated Dysfunctions Leading to Inflammatory Skin Disease

Control of adaptive immunity: from naïve to memory.

Cross-tissue immune cell analysis reveals tissue-specific features in humans

Cutting edge: Tissue-retentive lung memory CD4 T cells mediate optimal protection to respiratory virus infection

Developmental Regulation of Effector and Resident Memory T Cell Generation during Pediatric Viral Respiratory Tract Infection

Differential SLP-76 expression and TCR-mediated signaling in effector and memory CD4 T cells

Differential T cell receptor-mediated signaling in naive and memory CD4 T cells

Dissecting lung development and fibrosis at single-cell resolution

Distinct antibody responses to SARS-CoV-2 in children and adults across the COVID-19 clinical spectrum

Distribution and Compartmentalization of Human Circulating and Tissue-Resident Memory T Cell Subsets ⬇️

Early-life compartmentalization of human T cell differentiation and regulatory function in mucosal and lymphoid tissues

Emerging concepts in tissue-resident T cells: lessons from humans

Endogenous expansion of regulatory T cells leads to long-term islet graft survival in diabetic NOD mice

Enhancing alloreactivity does not restore GVHD induction but augments skin graft rejection by CD4+ effector memory T cells ⬇️

Form and function for T cells in health and disease

Functional heterogeneity of human tissue-resident memory T cells based on dye efflux capacities.

Functional plasticity of an antigen-specific memory CD4 T cell population.

Gene transfection and expression in resting and activated murine CD4 T cell subsets

Generation and functional capacity of polyclonal alloantigen-specific memory CD4 T cells.

Generation and persistence of human tissue-resident memory T cells in lung transplantation

Generation, homeostasis, and regulation of memory T cells in transplantation

Generation, persistence and plasticity of CD4 T-cell memories.

Human Lymph Nodes Maintain TCF-1 Memory T Cells with High Functional Potential and Clonal Diversity throughout Life

Human T Cell Development, Localization, and Function throughout Life

Human Tissue-Resident Memory T Cells Are Defined by Core Transcriptional and Functional Signatures in Lymphoid and Mucosal Sites

Human immunology studies using organ donors: Impact of clinical variations on immune parameters in tissues and circulation.

Human memory T cells: generation, compartmentalization and homeostasis

Identification and Targeting of Costimulation-Resistant T cells in Renal Transplantation ⬇️

Immunological memory: lessons from the past and a look to the future

Increased memory conversion of naïve CD8 T cells activated during late phases of acute virus infection due to decreased cumulative antigen exposure

Innate lymphoid cells promote anatomical containment of lymphoid-resident commensal bacteria.

Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus

Isoforms of the transmembrane tyrosine phosphatase CD45 differentially affect T cell recognition.

Location, location, location: Tissue resident memory T cells in mice and humans

Long-term Persistence of Innate Lymphoid Cells in the Gut After Intestinal Transplantation

Long-term islet graft survival in NOD mice by abrogation of recurrent autoimmunity

Lung niches for the generation and maintenance of tissue-resident memory T cells.

Macrochimerism in Intestinal Transplantation: Association With Lower Rejection Rates and Multivisceral Transplants, Without GVHD.

Maintenance of the human memory T cell repertoire by subset and tissue site

Memory CD4 T cells direct protective responses to influenza virus in the lungs through helper-independent mechanisms.

Memory CD4 T cells in influenza.

Memory T cells in transplantation: generation, function, and potential role in rejection.

Memory T-cell predominance following T-cell depletional therapy derives from homeostatic expansion of naive T cells

Microanatomical dissection of human intestinal T-cell immunity reveals site-specific changes in gut-associated lymphoid tissues over life

Modulation of the fungal mycobiome is regulated by the chitin-binding receptor FIBCD1

Molecular programs of fibrotic change in aging human lung

Mucosal resident memory CD4 T cells in protection and immunopathology

NF-κB signaling participates in both RANKL- and IL-4-induced macrophage fusion: receptor cross-talk leads to alterations in NF-κB pathways.

Novel phenotypes and migratory properties distinguish memory CD4 T cell subsets in lymphoid and lung tissue

Novel signaling interactions between proteinase-activated receptor 2 and Toll-like receptors in vitro and in vivo

Phenotypic alterations in pancreatic lymph node stromal cells from human donors with type 1 diabetes and NOD mice

Prolonged antigen presentation is required for optimal CD8+ T cell responses against malaria liver stage parasites

Pulse-oximetry accurately predicts lung pathology and the immune response during influenza infection

Recalling the year in memory T cells.

Reduced generation of lung tissue-resident memory T cells during infancy.

Remembrance of antigens past: new insights into memory T cells.

Reshaping the past: Strategies for modulating T-cell memory immune responses.

SARS-CoV-2 infection generates tissue-localized immunological memory in humans

Single-cell transcriptomics of human T cells reveals tissue and activation signatures in health and disease

Spatial and Temporal Mapping of Human Innate Lymphoid Cells Reveals Elements of Tissue Specificity

Splenic priming of virus-specific CD8 T cells following influenza virus infection

TLR2 engagement on dendritic cells promotes high frequency effector and memory CD4 T cell responses.

The MBP fusion protein restores the activity of the first phosphatase domain of CD45

The anti-tumor agent, 5,6-dimethylxanthenone-4-acetic acid (DMXAA), induces IFN-beta-mediated antiviral activity in vitro and in vivo

The neonatal window of opportunity-early priming for life.