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List of works by Andrew J Deans

A defined role for multiple Fanconi anemia gene products in DNA-damage-associated ubiquitination.

scientific article published on 15 March 2017

ALT control, delete: FANCM as an anti-cancer target in Alternative Lengthening of Telomeres

scientific article published on 01 December 2019

ASCIZ/ATMIN is dispensable for ATM signaling in response to replication stress.

scientific article published on 17 June 2017

ATP-dependent helicase activity is dispensable for the physiological functions of Recql4

scientific article published on 05 July 2019

Architecture and DNA Recognition Elements of the Fanconi Anemia FANCM-FAAP24 Complex

scientific article published on 3 September 2013

Author Correction: The FANCM-BLM-TOP3A-RMI complex suppresses alternative lengthening of telomeres (ALT)

scientific article published on 20 November 2019

BRCA1-BARD1 complexes are required for p53Ser-15 phosphorylation and a G1/S arrest following ionizing radiation-induced DNA damage

scientific article

Brca1 inactivation induces p27(Kip1)-dependent cell cycle arrest and delayed development in the mouse mammary gland.

scientific article published on August 2004

CX-5461 activates the DNA damage response and demonstrates therapeutic efficacy in high-grade serous ovarian cancer

scientific article published on 26 May 2020

Cyclin E2 induces genomic instability by mechanisms distinct from cyclin E1.

scientific article published on 16 January 2013

Cyclin-dependent kinase 2 functions in normal DNA repair and is a therapeutic target in BRCA1-deficient cancers

scientific article published on August 2006

DNA interstrand crosslink repair and cancer ⬇️

scientific article published on June 24, 2011

Expression of a truncated Brca1 protein delays lactational mammary development in transgenic mice

article

FANCM and FAAP24 function in ATR-mediated checkpoint signaling independently of the Fanconi anemia core complex

scientific article

FANCM connects the genome instability disorders Bloom's Syndrome and Fanconi Anemia

scientific article

FANCM limits ALT activity by restricting telomeric replication stress induced by deregulated BLM and R-loops

scientific article published on 28 May 2019

Fanconi proteins get histones moving.

scientific article

Granzyme A Deficiency Breaks Immune Tolerance and Promotes Autoimmune Diabetes Through a Type I Interferon-Dependent Pathway

scientific article published on 21 July 2017

Identification of KIAA1018/FAN1, a DNA repair nuclease recruited to DNA damage by monoubiquitinated FANCD2

scientific article

MAD1 and p27(KIP1) cooperate to promote terminal differentiation of granulocytes and to inhibit Myc expression and cyclin E-CDK2 activity

scientific article

MMTV-trBrca1 mice display strain-dependent abnormalities in vaginal development

scientific article published in September 2004

Mechanism of Ubiquitination and Deubiquitination in the Fanconi Anemia Pathway

scientific article published on 9 December 2016

Methodology for the identification of small molecule inhibitors of the Fanconi Anaemia ubiquitin E3 ligase complex

scientific article published on 14 May 2020

Monoubiquitination by the human Fanconi Anemia core complex clamps FANCI:FANCD2 on DNA in filamentous arrays

scientific article published on 13 March 2020

No evidence that CDKN1B (p27) polymorphisms modify breast cancer risk in BRCA1 and BRCA2 mutation carriers

scientific article published on 10 June 2008

Phosphorylation of Drosophila Brahma on CDK-phosphorylation sites is important for cell cycle regulation and differentiation

scientific article published on 14 July 2018

Preparation and purification of mono-ubiquitinated proteins using Avi-tagged ubiquitin

scientific article published on 24 February 2020

Structural insight into FANCI-FANCD2 monoubiquitination

scientific article published on 29 July 2020

The DNA translocase activity of FANCM protects stalled replication forks

scientific article published on 24 January 2012

The FA Core Complex Contains a Homo-dimeric Catalytic Module for the Symmetric Mono-ubiquitination of FANCI-FANCD2.

scientific article published on 09 December 2016

The FANCM-BLM-TOP3A-RMI complex suppresses alternative lengthening of telomeres (ALT)

scientific article published on 28 May 2019

The Fanconi Anemia Pathway Maintains Genome Stability by Coordinating Replication and Transcription

scientific article

The Fanconi anemia DNA repair pathway: structural and functional insights into a complex disorder

scientific article

The PTEN phosphatase functions cooperatively with the Fanconi anemia proteins in DNA crosslink repair

scientific article

The Rothmund-Thomson syndrome helicase RECQL4 is essential for hematopoiesis

scientific article

The architecture and evolution of cancer neochromosomes

scientific article published on 10 November 2014

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