List of works by William S Bush

<i>TNFRSF1B</i> Gene Variants and Related Soluble TNFR2 Levels Impact Resilience in Alzheimer's Disease

scientific article published on 25 February 2021

A balanced accuracy function for epistasis modeling in imbalanced datasets using multifactor dimensionality reduction.

scientific article

A comparison of cataloged variation between International HapMap Consortium and 1000 Genomes Project data

scientific article

A knowledge-driven interaction analysis reveals potential neurodegenerative mechanism of multiple sclerosis susceptibility.

scientific article published on 24 February 2011

A small number of candidate gene SNPs reveal continental ancestry in African Americans.

scientific article published on January 2013

Accuracy of administratively-assigned ancestry for diverse populations in an electronic medical record-linked biobank ⬇️

scientific article

Alternative contingency table measures improve the power and detection of multifactor dimensionality reduction

scientific article

Analysis of Heritability Using Genome-Wide Data

scientific article

Antibody-specific detection of caveolin-1 in subapical compartments of MDCK cells.

scientific article published on 28 January 2006

Antiepileptic activity of preferential inhibitors of persistent sodium current

scientific article

Are Interactions between cis-Regulatory Variants Evidence for Biological Epistasis or Statistical Artifacts?

scientific article published on 8 September 2016

Association Rule Discovery Has the Ability to Model Complex Genetic Effects

scientific article published on 01 March 2007

Association of Arrhythmia-Related Genetic Variants With Phenotypes Documented in Electronic Medical Records

scientific article published on January 2016

Associations between KCNJ6 (GIRK2) gene polymorphisms and pain-related phenotypes.

scientific article published on 28 August 2013

Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

scientific article published on 01 September 2019

Automated extraction of clinical traits of multiple sclerosis in electronic medical records

scientific article published on 22 October 2013

Automated quantification of pancreatic β-cell mass.

scientific article

Biofilter: a knowledge-integration system for the multi-locus analysis of genome-wide association studies.

scientific article

Bioinformatics challenges in genome-wide association studies (GWAS).

scientific article published on January 2014

Bridging the Gaps in Personalized Medicine Value Assessment: A Review of the Need for Outcome Metrics across Stakeholders and Scientific Disciplines

scientific article published on 27 August 2019

Catechol-O-methyltransferase polymorphism Val158Met is associated with distal neuropathic pain in HIV-associated sensory neuropathy

scientific article published on 01 August 2019

Cerebrospinal Fluid Ceruloplasmin, Haptoglobin, and Vascular Endothelial Growth Factor Are Associated with Neurocognitive Impairment in Adults with HIV Infection

scientific article published on 12 September 2018

Cerebrospinal fluid (CSF) biomarkers of iron status are associated with CSF viral load, antiretroviral therapy, and demographic factors in HIV-infected adults

scientific article

Chapter 11: Genome-wide association studies

scientific article

Characterization of the Metabochip in diverse populations from the International HapMap Project in the Epidemiologic Architecture for Genes Linked to Environment (EAGLE) project

scientific article published on January 2013

Comprehensive Analysis of Constraint on the Spatial Distribution of Missense Variants in Human Protein Structures

scientific article

Correction: Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation

scientific article published on 21 October 2019

Creation and Validation of an EMR-based Algorithm for Identifying Major Adverse Cardiac Events while on Statins

scientific article published on 07 April 2014

Cystic fibrosis-related diabetes is caused by islet loss and inflammation.

scientific article published on 19 April 2018

Discovery of gene-gene interactions across multiple independent data sets of late onset Alzheimer disease from the Alzheimer Disease Genetics Consortium

scientific article

Discussing gene-gene interaction: warning--translating equations to English may result in jabberwocky.

scientific article published in January 2007

European Mitochondrial DNA Haplogroups are Associated with Cerebrospinal Fluid Biomarkers of Inflammation in HIV Infection

scientific article published on September 2016

Evidence for extensive pleiotropy among pharmacogenes

scientific article published on June 2016

Evidence for polygenic susceptibility to multiple sclerosis--the shape of things to come

scientific article

Exploring epistasis in candidate genes for rheumatoid arthritis

scientific article

Extracting Country-of-Origin from Electronic Health Records for Gene- Environment Studies as Part of the Epidemiologic Architecture for Genes Linked to Environment (EAGLE) Study

scientific article

Fine-mapping analysis of a chromosome 2 region linked to resistance to Mycobacterium tuberculosis infection in Uganda reveals potential regulatory variants

article

Fine-mapping of lipid regions in global populations discovers ethnic-specific signals and refines previously identified lipid loci

scientific article

Frequency of ClinVar Pathogenic Variants in Chronic Kidney Disease Patients Surveyed for Return of Research Results at a Cleveland Public Hospital

scientific article published on 01 January 2020

Functional annotation of genomic variants in studies of late-onset Alzheimer's disease

scientific article published on 01 August 2018

GSK3β Interactions with Amyloid Genes: An Autopsy Verification and Extension

scientific article

Gene expression in cell lines from propionic acidemia patients, carrier parents, and controls.

scientific article published on 8 May 2015

Genetic Programming Neural Networks: A Powerful Bioinformatics Tool for Human Genetics

scientific article

Genetic Variation in Genes Underlying Diverse Dementias May Explain a Small Proportion of Cases in the Alzheimer's Disease Sequencing Project.

scientific article published on 27 February 2018

Genetic analysis of biological pathway data through genomic randomization

scientific article

Genetic and clinical risk prediction model for postoperative atrial fibrillation.

scientific article

Genetic interaction analysis among oncogenesis-related genes revealed novel genes and networks in lung cancer development

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

scientific article published on 28 February 2019

Genetic variants and functional pathways associated with resilience to Alzheimer's disease

scientific article published on 01 August 2020

Genetic variation in the rhythmonome: ethnic variation and haplotype structure in candidate genes for arrhythmias

scientific article

Genome-wide association study of HIV-associated neurocognitive disorder (HAND): A CHARTER group study

scientific article published on 26 April 2017

Genome-wide interaction study of smoking behavior and non-small cell lung cancer risk in Caucasian population

scientific article published on 20 October 2017

Genotype Correlation Analysis Reveals Pathway-Based Functional Disequilibrium and Potential Epistasis in the Human Interactome

scientific article published on 01 April 2014

Germline Genetic Variants and Lung Cancer Survival in African Americans

scientific article published on 15 June 2017

Hadoop and PySpark for reproducibility and scalability of genomic sequencing studies

scientific article published on 01 January 2020

Human islet preparations distributed for research exhibit a variety of insulin-secretory profiles.

scientific article

ICD-9 tobacco use codes are effective identifiers of smoking status

scientific article published on 09 February 2013

INTEGRATING COMMUNITY-LEVEL DATA RESOURCES FOR PRECISION MEDICINE RESEARCH.

scientific article published in January 2018

Identification of susceptibility pathways for the role of chromosome 15q25.1 in modifying lung cancer risk

scientific article published in Nature Communications

In Silico Functional Annotation of Genomic Variation.

scientific article

Interrogating the complex role of chromosome 16p13.13 in multiple sclerosis susceptibility: independent genetic signals in the CIITA-CLEC16A-SOCS1 gene complex

scientific article

Investigating the relationship between mitochondrial genetic variation and cardiovascular-related traits to develop a framework for mitochondrial phenome-wide association studies

scientific article

Is Isolated Low High-Density Lipoprotein Cholesterol a Cardiovascular Disease Risk Factor? New Insights From the Framingham Offspring Study

scientific article published on 10 May 2016

Knowledge-constrained K-medoids Clustering of Regulatory Rare Alleles for Burden Tests

scientific article published on 01 January 2013

Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes

scientific article published on 12 June 2017

Local ancestry transitions modify snp-trait associations

scientific article published in January 2018

Mitochondrial DNA Haplogroups and Neurocognitive Impairment During HIV Infection

scientific article

Modeling transcriptional regulation using gene regulatory networks based on multi-omics data sources

scientific article published on 19 April 2021

Nuclear-Mitochondrial interactions influence susceptibility to HIV-associated neurocognitive impairment

scientific article published on 17 July 2018

Packaging Biocomputing Software to Maximize Distribution and Reuse

scientific article published on 01 January 2020

Phenotyping Adverse Drug Reactions: Statin-Related Myotoxicity

scientific article published on 25 March 2015

Pleiotropic and sex-specific effects of cancer GWAS SNPs on melanoma risk in the population architecture using genomics and epidemiology (PAGE) study

scientific article

Pleiotropic associations of risk variants identified for other cancers with lung cancer risk: the PAGE and TRICL consortia

scientific article

Pleiotropic effects of genetic risk variants for other cancers on colorectal cancer risk: PAGE, GECCO and CCFR consortia

scientific article published on 09 August 2013

Predicting Incident Coronary Heart Disease Many Markers at a Time

scientific article published in December 2016

Protein-altering germline mutations implicate novel genes related to lung cancer development

scientific article published on 11 May 2020

Putting pleiotropy and selection into context defines a new paradigm for interpreting genetic data

scientific article

Quality control and integration of genotypes from two calling pipelines for whole genome sequence data in the Alzheimer's disease sequencing project

article

RNA editing alterations in a multi-ethnic Alzheimer disease cohort converge on immune and endocytic molecular pathways

scientific article published on 01 September 2019

Racial Disparities in Lung Cancer Survival: The Contribution of Stage, Treatment, and Ancestry

scientific article published on 06 June 2018

Rapid storage and retrieval of genomic intervals from a relational database system using nested containment lists.

scientific article

Rare genetic variation implicated in non-Hispanic white families with Alzheimer disease

Reducing Clinical Noise for Body Mass Index Measures Due to Unit and Transcription Errors in the Electronic Health Record

scientific article

Replication of associations between GWAS SNPs and melanoma risk in the Population Architecture Using Genomics and Epidemiology (PAGE) Study.

scientific article

SecureMA: protecting participant privacy in genetic association meta-analysis

scientific article

Sex differences in the genetic predictors of Alzheimer's pathology

scientific article published on 01 September 2019

Sex-Specific Association of Apolipoprotein E With Cerebrospinal Fluid Levels of Tau

scientific article published on 01 August 2018

Sex-Specific Parental Effects on Offspring Lipid Levels

scientific article

Sex-specific genetic predictors of Alzheimer's disease biomarkers

scientific article published on 02 July 2018

Somatic T-cell Receptor Diversity in a Chronic Kidney Disease PatientPopulation Linked to Electronic Health Records.

scientific article

The MafA transcription factor becomes essential to islet β-cells soon after birth.

scientific article

The phenotypic legacy of admixture between modern humans and Neandertals

scientific article

Three-dimensional spatial analysis of missense variants in RTEL1 identifies pathogenic variants in patients with Familial Interstitial Pneumonia.

scientific article published on 23 January 2018

Towards a phenome-wide catalog of human clinical traits impacted by genetic ancestry.

scientific article

Trans-ethnic analysis of metabochip data identifies two new loci associated with BMI.

scientific article published on 21 December 2017

Trans-ethnic fine-mapping of genetic loci for body mass index in the diverse ancestral populations of the Population Architecture using Genomics and Epidemiology (PAGE) Study reveals evidence for multiple signals at established loci

scientific article published on 8 April 2017

Transition-transversion encoding and genetic relationship metric in ReliefF feature selection improves pathway enrichment in GWAS

scientific article published on 03 November 2018

Two Novel Susceptibility Loci for Prostate Cancer in Men of African Ancestry.

scientific article published in August 2017

Unravelling the human genome-phenome relationship using phenome-wide association studies.

scientific article published on 15 February 2016

Utilization of an EMR-biorepository to identify the genetic predictors of calcineurin-inhibitor toxicity in heart transplant recipients

scientific article published on January 2014

Whole exome sequencing study identifies novel rare and common Alzheimer’s-Associated variants involved in immune response and transcriptional regulation

article

Whole genome sequencing of Caribbean Hispanic families with late-onset Alzheimer's disease.

scientific article published on 13 March 2018

Willingness to Participate in a National Precision Medicine Cohort: Attitudes of Chronic Kidney Disease Patients at a Cleveland Public Hospital

scientific article published on 26 June 2018

eMERGE Phenome-Wide Association Study (PheWAS) identifies clinical associations and pleiotropy for stop-gain variants

scientific article

eMERGEing progress in genomics-the first seven years

scientific article

Paulina is supported by:

About Paulina

Help