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List of works by Richard I. Shader

"Dem" back and neck and hand and knee and hip bones: pain and aging

scientific article published in November 2013

"Dingelling"

scientific article published on 01 December 1989

"Inflamma" and Other "Somes"

scientific article published on 29 December 2018

"Look-alikes" and generics

scientific article published on 01 April 1986

'GABA shift' in vivo: enhancement of benzodiazepine binding in vivo by modulation of endogenous GABA.

scientific article

11th European association for clinical pharmacology and therapeutics congress, 2013.

scientific article

2017, Sexual Dimorphism, Sexual Pluralism, and More

scientific article published on 27 December 2016

A Farewell to Arms, to Staff, to You, and to the Journal of Clinical Psychopharmacology

scientific article published on 14 October 2020

A Mentation on Mold

scientific article published on 09 June 2018

A New Year, a New Look ⬇️

scientific article published on January 1, 2013

A Note from the Editor-in-Chief Emeritus: A Reluctant Farewell to Clinical Therapeutics

scientific article published on 01 January 2020

A Tribute to Gertrude Belle Elion on the 100th Anniversary of her Birth

scientific article published on 30 January 2018

A benzodiazepine mood effect scale: reliability and validity determined for alcohol-dependent subjects and adults with a parental history of alcoholism

scientific article published in May 2001

A blueberry cocktail helps with memory loss: too good to be true?

scientific article published in August 2014

A controlled study of the effects of state surveillance on indicators of problematic and non-problematic benzodiazepine use in a Medicaid population

scientific article

A large-sample study of diazepam pharmacokinetics

scientific article

A new scale for clinical assessment in geriatric populations: Sandoz Clinical Assessment--Geriatric (SCAG).

scientific article published in March 1974

A patient of mine missed a period while taking fluoxetine; it turned out that she was not pregnant. However, the question arose about the safety of fluoxetine during pregnancy. What is known?

scientific article published on 01 June 1992

A possible new approach to the treatment of neuroleptic malignant syndrome

scientific article published on 01 June 1992

A proposal for a model psychopharmacology curriculum for psychiatric residents

scientific article published on 01 January 1993

A white paper on the appropriateness of proposals by the FDA to modify labeling of benzodiazepine sedative-hypnotics

scientific article published on 01 August 1994

Absence of interaction of cimetidine and ranitidine with intravenous and oral midazolam

scientific article published in February 1986

Absolute bioavailability and effect of food and antacid on diazepam absorption from a slow-release preparation

scientific article published in May 1984

Absolute bioavailability of imipramine: influence of food

scientific article published in January 1984

Absolute bioavailability of oral and intramuscular diazepam: effects of age and sex.

scientific article published in January 1983

Absorption and disposition of chlordiazepoxide in young and elderly male volunteers

scientific article published on 01 November 1977

Absorption and disposition of ibuprofen in the elderly

scientific article published on 01 September 1984

Absorption of oral and intramuscular chlordiazepoxide

scientific article published on 01 June 1978

Absorption rate, blood concentrations, and early response to oral chlordiazepoxide ⬇️

scientific article published on May 1, 1977

Abuse liability and clinical pharmacokinetics of alprazolam in alcoholic men

scientific article published on September 1, 1988

Accelerated benzodiazepine receptor recovery after lorazepam discontinuation ⬇️

scientific article published on 01 January 1991

Access to Clinical Therapeutics

scientific article published on 29 July 2015

Accidental Poisoning With Psychotropic Drugs in Children

scientific article published on May 1, 1976

Actual versus reported benzodiazepine usage by medical outpatients

scientific article published on 01 January 1987

Acute barbiturate administration increases benzodiazepine receptor binding in vivo

scientific article

Acute coronary syndromes, seedless watermelons, and colchicine

scientific article published on 01 August 2013

Acute overdosage with benzodiazepine derivatives ⬇️

scientific article published on April 1, 1977

Adherence Measurements in Clinical Trials and Care

scientific article published on 22 December 2017

Adverse effects of LSD: a current perspective

scientific article published on December 1, 1970

Adverse interactions encountered when using trazodone to treat insomnia associated with fluoxetine

scientific article

Adverse reactions to triazolam, flurazepam, and placebo in controlled clinical trials

scientific article published on May 1, 1984

Age and gender effects on chlordiazepoxide kinetics: relation to antipyrine disposition

scientific article published on 01 January 1989

Age and gender effects on the pharmacokinetics and pharmacodynamics of triazolam, a cytochrome P450 3A substrate

scientific article published in November 2004

Age, sex, and nitrazepam kinetics: relation to antipyrine disposition.

scientific article

Alarmins and More

scientific article published on 19 April 2016

Alcoholism in Women ⬇️

scientific article published on December 1, 1971

Alprazolam hydroxylation by mouse liver microsomes in vitro: the effect of age and phenobarbital induction

Alprazolam is another substrate for human cytochrome P450-3A isoforms.

scientific article published in June 1998

Alprazolam kinetics following sublingual and oral administration

scientific article published in October 1987

Alprazolam kinetics in the elderly. Relation to antipyrine disposition

scientific article published on 01 March 1983

Alprazolam metabolism in vitro: studies of human, monkey, mouse, and rat liver microsomes

scientific article published on 01 October 1993

Alprazolam pharmacokinetics in women on low-dose oral contraceptives

scientific article published on 01 May 1988

Alprazolam pharmacokinetics, metabolism, and plasma levels: clinical implications.

scientific article

Alprazolam, panic disorder, and the new 2 mg tablet.

scientific article published in June 1991

Alprazolam-induced mania: two clinical cases

scientific article

Alprazolam-ritonavir interaction: implications for product labeling

scientific article published on 01 April 2000

Alterations in drug distribution and clearance due to obesity ⬇️

scientific article published on June 1, 1981

Alterations in pharmacodynamics of anxiolytics in abstinent alcoholic men: subjective responses, abuse liability, and electroencephalographic effects of alprazolam, diazepam, and buspirone

scientific article published in January 1997

Alumni of the Massachusetts mental health center residency training

scientific article published on April 1976

Amoxapine, an observation, and a perspective on MAOIs and their safety

scientific article published on 01 September 1981

An Anecdote About Arthritis and Boswellia serrata

scientific article published on 04 May 2018

An evaluation of isoquinazepon (SAH-1123).

scientific article published in October 1967

An interactive model for panic disorders.

scientific article published in August 1984

An investigation of the stimulating and mood-elevating properties of pipradol HCl administered to clinically normal volunteers.

scientific article published in March 1968

Analysis of lorazepam and its glucuronide metabolite by electron-capture gas--liquid chromatography. Use in pharmacokinetic studies of lorazepam

scientific article published on 01 September 1978

Antagonists, inverse agonists, and protagonists.

scientific article

Antidepressants as hydrobromide salts: are they a cause for concern?

scientific article published in August 2009

Antidepressants: The Second Harvest and DSM-III ⬇️

scientific article published on 01 March 1981

Antimicrobial stewardship

scientific article published on 01 June 2013

Antipyretic analgesic drugs as models for studies of drug disposition in old age

scientific article published on 01 November 1983

Antipyrine Absorption and Disposition in the Elderly ⬇️

scientific article published on January 1, 1988

Antipyrine kinetics in the elderly: prediction of age-related changes in benzodiazepine oxidizing capacity

scientific article published on 01 January 1982

Anxiolytic drug therapy in patients with medical disease: clinical importance of pharmacokinetic drug interactions

scientific article published on January 1, 1984

Appetite suppressant drugs as inhibitors of human cytochromes P450: in vitro inhibition of P450-2D6 by D- and L-fenfluramine, but not phentermine

scientific article published on 01 August 1998

Appropriate Use and Regulatory Control of Benzodiazepines ⬇️

scientific article published on September 1, 1991

Are any antianxiety agents safer for patients who spend a great deal of time in direct sunlight?

scientific article published on 01 April 1992

Associations About Arthritis

scientific article published on 10 June 2019

Assumptions in Clinical Trial Designs and Therapies

scientific article published on 03 November 2018

Atropine overdose in three children

scientific article published in July 1972

Augmentation of GABAA receptor function by chronic exposure to GABA-neutral and GABA-negative benzodiazepine ligands in cultured cortical neurons

scientific article published on 01 September 1990

Automated gas chromatographic determination of plasma alprazolam concentrations

scientific article published on 01 December 1983

Baby Fat or a Fat Baby?

scientific article published on 24 September 2018

Back to basics--diagnosis before treatment: homelessness, hypothyroidism, aging, and lithium

scientific article published on 01 December 1987

Bees, ginseng and MAOIs revisited

scientific article published on 01 August 1988

Behavioral correlates of the guessing game. Side effects and double-blind studies

scientific article published on 01 September 1966

Behavioral toxicity and equivocal suicide associated with chloroquine and its derivatives ⬇️

scientific article published on July 1, 1977

Behavioral toxicity of psychotropic drugs. 3. Effects on perceptual and cognitive functions. IV. Effects on emotional (mood) states

scientific article

Behavioral toxicity of psychotropic drugs. I. Definition. II. Toxic effects on psychomotor functions

scientific article published on 01 August 1968

Behavioral toxicity of psychotropic drugs. V. Effects on gross behavior patterns

scientific article published on 01 April 1969

Behavioural reactions to triazolam

scientific article published on 01 November 1979

Benzodiazepine discontinuation syndromes

scientific article published on January 1990

Benzodiazepine drug-drug interactions commonly occurring in clinical practice

scientific article published on 01 January 1984

Benzodiazepine hypnotic metabolism: drug interactions and clinical implications

scientific article published in January 1986

Benzodiazepine hypnotics.

scientific article published in August 1990

Benzodiazepine hypnotics: kinetic and therapeutic options.

scientific article published in January 1982

Benzodiazepine kinetics: implications for therapeutics and pharmacogeriatrics

scientific article published on January 1983

Benzodiazepine overdosage: plasma concentrations and clinical outcome

scientific article published in January 1981

Benzodiazepine overuse-misuse

scientific article published on 01 June 1984

Benzodiazepine receptor binding of triazolobenzodiazepines in vivo: increased receptor number with low-dose alprazolam

scientific article

Benzodiazepine receptor binding response to acute and chronic stress is increased in aging animals

scientific article published in January 1991

Benzodiazepine receptor binding: influence of physiologic and pharmacologic factors

scientific article published on March 1987

Benzodiazepine receptor occupancy in vivo: correlation with brain concentrations and pharmacodynamic actions.

scientific article published in February 1987

Benzodiazepine use and risk for Alzheimer disease

scientific article published in February 2015

Benzodiazepines and pregnancy--more to say and more to learn

scientific article published on 01 August 1989

Benzodiazepines during early pregnancy.

scientific article published in April 1984

Benzodiazepines in clinical medicine: discussion ⬇️

scientific article published on January 1, 1981

Benzodiazepines, antidepressants and addiction: A plea for conceptual rigor and consistency

scientific article published on 26 September 2019

Benzodiazepines: Safety and toxicity

scientific article published on May 1, 1975

Benzodiazepines: Some Aspects of Their Clinical Pharmacology ⬇️

scientific article published on January 1, 1979

Benzodiazepines: a summary of pharmacokinetic properties ⬇️

scientific article published on January 1, 1981

Benzodiazepines: it's time to return to the evidence

scientific article published on 12 October 2020

Biasing factors in diagnosis and disposition ⬇️

scientific article published in March 1969

Bioequivalence of generic drugs in clinical psychopharmacology

scientific article published on 01 February 1987

Bioequivalence studies in the elderly: a pilot study of two oxazepam dosage forms

scientific article published on 01 June 1987

Bioinequivalence of a generic brand of diazepam

scientific article published in November 1989

Biotransformation of chlorzoxazone by hepatic microsomes from humans and ten other mammalian species

scientific article published on 01 April 1997

Biotransformation of mestranol to ethinyl estradiol in vitro: the role of cytochrome P-450 2C9 and metabolic inhibitors

scientific article published on 01 March 1997

Bromazepam pharmacokinetics: influence of age, gender, oral contraceptives, cimetidine, and propranolol

scientific article

COVID-19 and Depression

scientific article published on 27 April 2020

COVID-19, interferons, and depression: A commentary

scientific article published on 06 June 2020

CYP2B6 mediates the in vitro hydroxylation of bupropion: potential drug interactions with other antidepressants.

scientific article

CYP3A4 is the major CYP isoform mediating the in vitro hydroxylation and demethylation of flunitrazepam.

scientific article

Caffeine-induced behavioral stimulation is dose-dependent and associated with A1 adenosine receptor occupancy

scientific article published on May 1, 1992

Caffeine-induced behavioural stimulation is dose- and concentration-dependent

scientific article published on July 1990

Can Beliefs Be Modified?

scientific article published on 24 May 2019

Can lithium cause hair loss?

scientific article published on 01 April 1983

Can you provide a table of equivalences for benzodiazepines and other marketed benzodiazepine receptor agonists?

scientific article published on 01 August 1997

Cancer chemotherapy: a rapidly moving train

scientific article published on 01 September 2013

Cancer in the Elderly

scientific article published on 30 March 2018

Canny cases. Case 4: A precipitate poisoning

scientific article published on 01 April 1995

Canny cases. Case 5: the dextral dodder

scientific article published on 01 June 1995

Cardiac effects of imipramine hydrochloride in the elderly

scientific article published on January 1, 1975

Cardiac side effects and sudden death in hospitalized psychiatric patients

scientific article published on 01 February 1977

Cardiovascular effects of psychotropic drugs

scientific article published on 01 November 1969

Case 6: a free solution

scientific article published on 01 August 1995

Case 8: the wambly sophomaniac

scientific article published on 01 December 1995

Case Reports and Informed Consent

Cell-to-cell talk: plasmids and exosomes

scientific article published on 01 June 2014

Central nervous system drug development, basic, and clinical research: thinking outside the box

scientific article published on 01 October 2011

Cervical Cancer and Human Papilloma Virus

scientific article published in March 2016

Changes in cognition, attention and language in acute schizophrenia

scientific article published on 01 January 1969

Characterization of six in vitro reactions mediated by human cytochrome P450: application to the testing of cytochrome P450-directed antibodies

scientific article published on 01 February 1996

Characterological Anxiety Levels and Premenstrual Libido Changes ⬇️

scientific article

Chlordiazepoxide, expectation and hostility

scientific article published on 01 January 1969

Chlordiazepoxide-induced hostility in a small group setting

scientific article published in September 1974

Chronic administration of benzodiazepines--V. Rapid onset of behavioral and neurochemical alterations after discontinuation of alprazolam

scientific article

Chronic benzodiazepine administration. I. Tolerance is associated with benzodiazepine receptor downregulation and decreased gamma-aminobutyric acidA receptor function

scientific article

Chronic benzodiazepine administration. II. Discontinuation syndrome is associated with upregulation of gamma-aminobutyric acidA receptor complex binding and function.

scientific article

Chronic benzodiazepine administration. III. Upregulation of gamma-aminobutyric acidA receptor binding and function associated with chronic benzodiazepine antagonist administration.

scientific article

Chronic benzodiazepine administration. IV. Rapid development of tolerance and receptor downregulation associated with alprazolam administration

scientific article

Chronic benzodiazepine administration. IX. Attenuation of alprazolam discontinuation effects by carbamazepine

scientific article published in December 1991

Chronic benzodiazepine administration. VI. A partial agonist produces behavioral effects without tolerance or receptor alterations

scientific article published on July 1990

Chronic benzodiazepine administration. VII. Behavioral tolerance and withdrawal and receptor alterations associated with clonazepam administration

scientific article published in January 1991

Chronic benzodiazepine administration. X. Concurrent administration of the peripheral-type benzodiazepine ligand PK11195 attenuates chronic effects of lorazepam ⬇️

scientific article published on April 1, 1992

Chronic benzodiazepine administration. XI. Concurrent administration of PK11195 attenuates lorazepam discontinuation effects

scientific article

Chronic benzodiazepine administration. XII. Anticonvulsant cross-tolerance but distinct neurochemical effects of alprazolam and lorazepam

scientific article published in January 1993

Chronic benzodiazepine administration: effects in vivo and in vitro

scientific article published on January 1990

Chronic low-dose alprazolam augments gamma-aminobutyric acid(A) receptor function

scientific article published on April 1, 1992

Chronic morphine administration augments benzodiazepine binding and GABAA receptor function

scientific article published on 01 January 1990

Cimetidine impairs clearance of antipyrine and desmethyldiazepam in the elderly

scientific article published on 01 November 1982

Citalopram and desmethylcitalopram in vitro: human cytochromes mediating transformation, and cytochrome inhibitory effects.

scientific article published on September 1999

Clearance of the antihistamine doxylamine. Reduced in elderly men but not in elderly women

scientific article published on 01 May 1989

Clinical Pharmacokinetics of Chlordiazepoxide

scientific article published on September 1, 1978

Clinical Pharmacokinetics of Lorazepam. III. Intravenous Injection. Preliminary Results ⬇️

scientific article published on August 1, 1977

Clinical Pharmacokinetics of Lorazepam. IV. Long-Term Oral Administration ⬇️

scientific article published on August 1, 1977

Clinical Pharmacokinetics of the Newer Benzodiazepines

scientific article published on May 1, 1983

Clinical Pharmacology and Therapeuticsof Antidepressants

scholarly article published 25 October 2010

Clinical implications of benzodiazepine pharmacokinetics ⬇️

scientific article published on June 1, 1977

Clinical importance of the interaction of diazepam and cimetidine

scientific article published in June 1984

Clinical indications for plasma level monitoring of psychotropic drugs ⬇️

scientific article published on December 1, 1979

Clinical pharmacokinetics of antidepressants in the elderly. Therapeutic implications

scientific article

Clinical pharmacokinetics of anxiolytics and hypnotics in the elderly. Therapeutic considerations (Part I).

scientific article published on September 1991

Clinical pharmacokinetics of anxiolytics and hypnotics in the elderly. Therapeutic considerations (Part II).

scientific article published on October 1991

Clinical pharmacokinetics of chlordiazepoxide

scientific article published on 01 October 1975

Clinical pharmacokinetics of lorazepam. I. Absorption and disposition of oral 14C-lorazepam

scientific article published on September 1, 1976

Clinical pharmacokinetics of lorazepam: a review

scientific article published on October 1, 1978

Clinical pharmacokinetics of lorazepam; II. Intramuscular injection ⬇️

scientific article published on February 1, 1977

Clinical psychopharmacology and the elderly patient

scientific article published on January 1, 1976

Clinical use of the benzodiazepines

scientific article published in October 1981

ClinicalTrials.gov, Inhaled Loxapine, and Safety Issues

scientific article published on 01 April 2017

Clobazam kinetics in the elderly ⬇️

scientific article published on November 1, 1981

Clobazam kinetics: intrasubject variability and effect of food on adsorption

scientific article published in January 1982

Clonazepam pharmacokinetics, brain uptake, and receptor interactions.

scientific article

Close correlation of acetaminophen clearance with that of conjugated benzodiazepines but not oxidized benzodiazepines

scientific article published on 01 January 1983

Clozapine and fluvoxamine, a curious complexity

scientific article published on 01 April 1998

Clozapine--a perspective. Accepted as a consensus statement by the ACNP Council, August 13, 1990.

scientific article published on February 1991

Cocaine augments peripheral benzodiazepine binding in humans

scientific article published in October 1990

Cognitive effects of beta-adrenergic antagonists after single doses: pharmacokinetics and pharmacodynamics of propranolol, atenolol, lorazepam, and placebo

scientific article published in May 1993

Collagen disease-like syndrome following administration of a benzodiazepine derivative

scientific article published on 01 September 1967

Comments on Chronic Fatigue Syndrome

scientific article published on 27 March 2019

Comments on Watson, the Microbiome of Children, and Patient-reported Outcomes.

scientific article

Comparative effects of single and repeat dose administration of antianxiety agents

scientific article published on October 1, 1971

Comparative kinetics and dynamics of zaleplon, zolpidem, and placebo

scientific article published in November 1998

Comparative kinetics and response to the benzodiazepine agonists triazolam and zolpidem: evaluation of sex-dependent differences

scientific article published in May 2000

Comparative single-dose kinetics and dynamics of lorazepam, alprazolam, prazepam, and placebo

scientific article

Concomitant estrogen use has been alleged to increase the side effects of certain oxidatively-metabolized psychiatric drugs. Are there any estrogen-free oral contraceptives (OCs)?

scientific article published on 01 June 1989

Conflicts of interest, redundant publication, and identification of authorship: a plea for trust instead of suspicion.

scientific article published in June 1998

Contraceptive effectiveness: cytochromes and induction

scientific article published on 01 April 2000

Correlates of outcome following acute glutethimide overdosage

scientific article published on January 1, 1979

Correlating pharmacokinetics and pharmacodynamics of benzodiazepines: problems and assumptions.

scientific article published in January 1987

Correlation of human menstruation and lunar phase ⬇️

scientific article published on April 15, 1975

Critical review of liability for benzodiazepine abuse among alcoholics

scientific article published on December 1988

Cytochromes in psychopharmacology

scientific article published on 01 February 1994

Decreased EEG Sensitivity to Alprazolam in Subjects with a Parental History of Alcoholism

scientific article published on 01 January 2000

Demoralization revisited

scientific article published on 01 August 2005

Dependence, Tolerance, and Addiction to Benzodiazepines: Clinical and Pharmacokinetic Considerations ⬇️

scientific article published on January 1, 1978

Depression in the Elderly. I. Relationship between Depression, Psychologic Defense Mechanisms and Physical Illness* ⬇️

scientific article published on June 1, 1978

Depression in the elderly. II. Possible drug etiologies; differential diagnostic criteria

scientific article published on July 1, 1978

Desmethyldiazepam kinetics in the elderly after oral prazepam

scientific article

Desmethyldiazepam pharmacokinetics: studies following intravenous and oral desmethyldiazepam, oral clorazepate, and intravenous diazepam

scientific article published in September 1988

Diabetes, More on Merde, the Microbiome, and the Dung Beetle

scientific article published on 01 June 2015

Diazepam absorption: effect of antacids and food

scientific article published on November 1978

Diazepam disposition determinants

scientific article published in March 1980

Diazepam in the Elderly: Looking Back, Ahead, and at the Evidence

scientific article published on 01 May 2020

Differences in pharmacodynamics but not pharmacokinetics between subjects with panic disorder and healthy subjects after treatment with a single dose of alprazolam

scientific article published on 01 June 2000

Differential actions of chlordiazepoxide and oxazepam on hostility

scientific article published in June 1968

Differential effect of cimetidine on drug oxidation (antipyrine and diazepam) vs. conjugation (acetaminophen and lorazepam): prevention of acetaminophen toxicity by cimetidine

scientific article published in March 1983

Differential effects of chronic lorazepam and alprazolam on benzodiazepine binding and GABAA-receptor function

scientific article published on December 1990

Differential impairment of triazolam and zolpidem clearance by ritonavir

scientific article published in June 2000

Differential modulation of benzodiazepine receptor binding by ethanol in LS and SS mice

scientific article

Difficulties in the clinical diagnosis of lithium toxicity ⬇️

scientific article published on 01 September 1979

Disclosures

scientific article published on 28 December 2018

Discontinue after last dose--an editorial and information about prescription writing

scientific article published on 01 June 2002

Distinguishing a benzodiazepine agonist (triazolam) from a nonagonist anxiolytic (buspirone) by electroencephalography: kinetic-dynamic studies

scientific article published in July 1994

Does carbamazepine-induced reduction of plasma haloperidol levels worsen psychotic symptoms?

scientific article published on 01 May 1986

Does continuous use of fluoxetine during the first trimester of pregnancy present a high risk for malformation or abnormal development to the exposed fetus?

scientific article published on 01 December 1992

Dose dumping and the dumping of doses

scientific article published in August 2007

Dose‐Dependent Pharmacokinetics and Psychomotor Effects of Caffeine in Humans ⬇️

scientific article published on August 1, 1997

Draft legislation: the Science Research Protection Act of 1990

scientific article published on 01 December 1990

Drug Administration Schedules ⬇️

scientific article

Drug Safety, Climate Change, Causality, and Predictability.

scientific article

Drug absorption rate: a critical component of bioequivalence assessment in psychopharmacology

scientific article published on 01 February 1987

Drug abuse and the emergency room physician.

scientific article published in May 1974

Drug administration schedules

scientific article published on January 1, 1971

Drug interactions involving psychotropic drugs

scientific article published on 01 November 1978

Drug interactions with grapefruit juice: an update

scientific article (publication date: August 2001)

Drug interactions with newer antidepressants: role of human cytochromes P450

scientific article published on 01 January 1998

Drug therapy reviews: rational use of psychotropic drugs. III. Major tranquilizers.

scientific article published on October 1974

Drug therapy. Anticholinergics

scientific article published on June 1973

Drug therapy. Benzodiazepines (first of two parts).

scientific article published on November 1974

Drug therapy. Benzodiazepines (second of two parts).

scientific article published on December 1974

Drug therapy. Current status of benzodiazepines

scientific article published on August 1983

Drug therapy. Current status of benzodiazepines

scientific article

Drug therapy: drug disposition in old age.

scientific article published on May 1982

Drug-attributed Hepatic Failure: Causality, Risk Assessment, Consent, and Confusion ⬇️

scientific article published on 01 December 2003

Drugs Five Years Later

scientific article published on August 1, 1975

Drugs in the management of anxiety

scientific article published on January 1, 1971

Drugs, populations, and type II diabetes mellitus

scientific article published on 01 April 2014

Editor's note: Clinical trial designs and statistics made easy

scientific article published on 01 February 2014

Editors' note: New Board of International Consulting Editors (BICE)

scientific article published in February 2013

Editors' note: retraction notice

scientific article published in December 2014

Effect of Abdominal Radiation Therapy on Drug Absorption in Humans ⬇️

scientific article published on August 1, 1978

Effect of age and Billroth gastrectomy on absorption of desmethyldiazepam from clorazepate ⬇️

scientific article published on October 1, 1979

Effect of age and gender on disposition of temazepam ⬇️

scientific article published on October 1, 1981

Effect of age and sex on disposition of desmethyldiazepam formed from its precursor clorazepate

scientific article published in January 1981

Effect of age, body composition, and lipid solubility on benzodiazepine tissue distribution in rats.

scientific article

Effect of age, gender, and obesity on midazolam kinetics.

scientific article published in July 1984

Effect of blood collection tubes on antidepressant concentrations

scientific article published on 01 December 1987

Effect of gradual withdrawal on the rebound sleep disorder after discontinuation of triazolam

scientific article published on September 1987

Effects of Chlordiazepoxide and Oxazepam Administration on Verbal Hostility ⬇️

scientific article published on December 1, 1977

Effects of age and other drugs on benzodiazepine kinetics

scientific article published on 01 January 1980

Effects of age on in vitro midazolam biotransformation in male CD-1 mouse liver microsomes.

scientific article published in March 2000

Effects of ketoconazole on triazolam pharmacokinetics, pharmacodynamics and benzodiazepine receptor binding in mice ⬇️

scientific article published on April 1, 1998

Electron-capture gas chromatographic analysis of the triazolobenzodiazepines alprazolam and triazolam ⬇️

scientific article published on September 11, 1981

Elements of a Good Scientific Paper.

scientific article

Endocrine and metabolic effects of psychotropic drugs. IV. Hypothalamic-pituitary-adrenal axis

scientific article

Endocrine effects of psychotropic drugs. 1. Galactorrhea and gynecomastia

scientific article published in February 1968

Endocrine effects of psychotropic drugs. 3. Glucose metabolism

scientific article published on 01 May 1968

Endocrine effects of psychotropic drugs. II. Amenorrhea

scientific article published on 01 April 1968

Endocrine effects of psychotropic drugs: V. Pituitary-thyroid axis

scientific article

Endocrine effects of psychotropic drugs: VI. Male sexual function

scientific article published on 01 November 1968

Enhanced bioavailability of triazolam following sublingual versus oral administration

scientific article published on 01 March 1986

Enhanced glucuronide conjugation of drugs in obesity: studies of lorazepam, oxazepam, and acetaminophen

scientific article published on 01 June 1983

Enzyme kinetic modelling as a tool to analyse the behaviour of cytochrome P450 catalysed reactions: application to amitriptyline N-demethylation

scientific article published on June 1996

Epiphenomenal, causal, or correlational--more on the mechanism(s) of action of antidepressants

scientific article published in August 1998

Errors in science versus scientific fraud

scientific article published on 01 April 1989

Escitalopram (S-citalopram) and its metabolites in vitro: cytochromes mediating biotransformation, inhibitory effects, and comparison to R-citalopram

scientific article published in August 2001

Extensive impairment of triazolam and alprazolam clearance by short-term low-dose ritonavir: the clinical dilemma of concurrent inhibition and induction

scientific article published in August 1999

Extrapolating in vitro data on drug metabolism to in vivo pharmacokinetics: evaluation of the pharmacokinetic interaction between amitriptyline and fluoxetine.

scientific article

Extrapyramidal side effects of psychotropic drugs

scientific article published on 01 March 1969

Factors influencing blood concentrations of chlordiazepoxide: a use of multiple regression analysis

scientific article published on 01 November 1977

Factors influencing diazepam pharmacokinetics: age, sex, and liver disease

scientific article published in April 1978

Factors influencing variability in clinical trials and in individuals' responses to treatment.

scientific article published in July 2013

Facts and public policy: should I keep my child on ADHD drugs?

scientific article published on 01 June 2006

Falls, Frailty, Vision, and Aging

scientific article published on 01 March 2019

Fatal hyperthermia following haloperidol therapy of sedative-hypnotic withdrawal

scientific article

Five Distinct Human Cytochromes Mediate Amitriptyline N‐Demethylation In Vitro: Dominance of CYP 2C19 and 3A4 ⬇️

scientific article published on 01 February 1998

Fluoxetine drug-drug interactions. II.

scientific article published on June 1990

Fluoxetine drug-drug interactions: I. Antidepressants and antipsychotics

scientific article published on February 1990

Fluoxetine inhibition of phenytoin metabolism

scientific article published on 01 December 1994

Flurazepam hydrochloride ⬇️

scientific article published on January 1, 1975

Flurazepam hydrochloride, a benzodiazepine hypnotic

scientific article

Foods, genetics, and drug interactions

scientific article published on 01 June 2003

Forgotten Influences and Reflections on Exercise and on the End of the Year 2017.

scientific article published on 24 November 2017

From disordered eating to addiction: the "food drug" in bulimia nervosa.

scientific article published on June 2012

Fruit juices and pharmacology

scientific article published on 01 August 1997

Further Thoughts about Opioids and Cannabinoids

scientific article published on 28 August 2019

Gas chromatographic analysis of alprazolam in plasma: replicability, stability and specificity

scientific article published on 01 December 1990

Genomics and the Prediction and Characterization of Cancer and Some Observations About Pancreatic Cancer

scientific article published on 23 June 2016

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Halazepam, another precursor of desmethyldiazepam ⬇️

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Haloperidol determination in serum and cerebrospinal fluid using gas--liquid chromatography with nitrogen--phosphorus detection: application to pharmacokinetic studies

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Health care reform

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Herpes and clinical psychopharmacology.

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Human cytochromes mediating sertraline biotransformation: seeking attribution

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IN VITRO QUANTITATION OF BENZODIAZEPINE LIPOPHILICITY: RELATION TO IN VIVO DISTRIBUTION

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Imipramine and desipramine disposition in the elderly

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Imipramine disposition in users of oral contraceptive steroids

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Imipramine-cimetidine interaction: impairment of clearance and enhanced absolute bioavailability

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Impaired absorption of desmethyldiazepam from clorazepate by magnesium aluminum hydroxide ⬇️

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Impairment of diazepam metabolism by low-dose estrogen-containing oral-contraceptive steroids

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Impairment of hepatic drug oxidation by propoxyphene

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Implications of altered drug disposition in the elderly: studies of benzodiazepines

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In situ hybridization histochemistry as a method to assess GABA(A) receptor subunit mRNA expression following chronic alprazolam administration

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In vitro approaches to predicting drug interactions in vivo.

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In vitro biotransformation of sildenafil (Viagra) in the male rat: the role of CYP2C11.

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In vitro biotransformation of sildenafil (Viagra): identification of human cytochromes and potential drug interactions

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In vitro correlates of benzodiazepine cerebrospinal fluid uptake, pharmacodynamic action and peripheral distribution

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In vitro metabolism of trazodone by CYP3A: inhibition by ketoconazole and human immunodeficiency viral protease inhibitors.

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In vitro prediction of the terfenadine-ketoconazole pharmacokinetic interaction

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Influence of magnesium and aluminum hydroxide mixture on chlordiazepoxide absorption

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Influence of oral contraceptive use and cigarette smoking, alone and together, on antipyrine pharmacokinetics

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Influenza vaccines-thoughts and current status.

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Informed Consent and Assent in Pediatric Oncology Trials

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Inhibition of cytochrome P450 by nefazodone in vitro: studies of dextromethorphan O- and N-demethylation

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Inhibition of desipramine hydroxylation (Cytochrome P450-2D6) in vitro by quinidine and by viral protease inhibitors: relation to drug interactions in vivo

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Inhibition of desipramine hydroxylation in vitro by serotonin-reuptake-inhibitor antidepressants, and by quinidine and ketoconazole: a model system to predict drug interactions in vivo

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Inhibition of human cytochrome P450 isoforms by nonnucleoside reverse transcriptase inhibitors

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Inhibition of human cytochrome P450 isoforms in vitro by zafirlukast

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Inhibition of human cytochrome P450-3A isoforms by fluoxetine and norfluoxetine: in vitro and in vivo studies

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Inhibition of terfenadine metabolism in vitro by azole antifungal agents and by selective serotonin reuptake inhibitor antidepressants: relation to pharmacokinetic interactions in vivo

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Inhibition of triazolam clearance by macrolide antimicrobial agents: in vitro correlates and dynamic consequences

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Inhibitors of alprazolam metabolism in vitro: effect of serotonin-reuptake-inhibitor antidepressants, ketoconazole and quinidine

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Interaction of Cimetidine with Oxazepam, Lorazepam, and Flurazepam ⬇️

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Interaction of caffeine with the GABAA receptor complex: alterations in receptor function but not ligand binding

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Interaction of cimetidine with the triazolobenzodiazepines alprazolam and triazolam

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Interaction of diazepam with famotidine and cimetidine, two H2-receptor antagonists

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Interaction of propoxyphene with diazepam, alprazolam and lorazepam

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Interaction of triazolam and ketoconazole

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International Task Force on Benzodiazepines

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Kinetic Characterization and Identification of the Enzymes Responsible for the Hepatic Biotransformation of Adinazolam and N-Desmethyladinazolam in Man ⬇️

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Kinetic and dynamic components of increased benzodiazepine sensitivity in aging animals

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Kinetic and dynamic interaction of brotizolam and ethanol

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Kinetic and dynamic study of intravenous lorazepam: comparison with intravenous diazepam

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Kinetics and EEG effects of midazolam during and after 1-minute, 1-hour, and 3-hour intravenous infusions.

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Kinetics and clinical effects of flurazepam in young and elderly noninsomniacs

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Kinetics and dynamics of lorazepam during and after continuous intravenous infusion

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Kinetics and dynamics of single doses of oxazepam in the elderly: implications of absorption rate

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Kinetics of Oxazepam and Lorazepam in Two Subjects with Gilbert Syndrome* ⬇️

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Kinetics of intravenous chlordiazepoxide: sex differences in drug distribution

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Kinetics, brain uptake, and receptor binding characteristics of flurazepam and its metabolites

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Kynurenine--an old pathway retraced

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Langner's Psychiatric Impairment Scale: A Short Screening Device ⬇️

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Letter: Safety of nitrazepam.

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Liability to alprazolam abuse in daughters of alcoholics

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Liquid chromatographic determination of chlordiazepoxide and metabolites in plasma

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Lithium and marijuana

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Lithium and the newborn heart

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Lithium nephropathy and antipyretic analgesics--an uncontrolled variable

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Long term therapy of chronic schizophrenia; a reply by the authors

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Long v short half-life benzodiazepines in the elderly. Kinetics and clinical effects of diazepam and oxazepam

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Long-term administration of benzodiazepines: pharmacokinetic versus pharmacodynamic tolerance

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Long-term treatment of chronic schizophrenia. A preliminary report

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Lorazepam and oxazepam kinetics in women on low-dose oral contraceptives

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Lorazepam attenuates the behavioral effects of dizocilpine.

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Lorazepam discontinuation promotes 'inverse agonist' effects of benzodiazepines

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Lorazepam kinetics in the elderly ⬇️

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Low-dose alprazolam augments motor activity in mice

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MAOIs and drug interactions--a proposal for a clearinghouse

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MAOIs and hypertension

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Management of anxiety in the elderly: the balance between therapeutic and adverse effects.

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Marihuana users and nonusers. Personality test differences

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Marijuana and hostility in a small-group setting

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Mass units or molar units for drug concentration?

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Measurement of Staff Attitudes and the Clinical Course of Patients on a Psychiatric Ward

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MedWatch, the new FDA adverse effects reporting system

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Meditation and Mindfulness

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Menarcheal age and personality: the choice of a statistical test of relationship

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Mental illness, pharmacotherapy, and automobile operation: what is the risk?

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Meprobamate: A Study of Irrational Drug Use ⬇️

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Metabolism of dextromethorphan in vitro: involvement of cytochromes P450 2D6 and 3A3/4, with a possible role of 2E1.

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Metabolism of drugs by cytochrome P450 3A isoforms. Implications for drug interactions in psychopharmacology.

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Metabolism of haloperidol: clinical implications and unanswered questions

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Metabolism of the antidepressant mirtazapine in vitro: contribution of cytochromes P-450 1A2, 2D6, and 3A4

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Methadone withdrawal in the treatment of heroin addiction

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Methaqualone abusers: a preliminary survey of college students

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Midazolam and triazolam biotransformation in mouse and human liver microsomes: relative contribution of CYP3A and CYP2C isoforms.

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Midazolam hydroxylation by human liver microsomes in vitro: inhibition by fluoxetine, norfluoxetine, and by azole antifungal agents

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Misconduct in science and misconduct against scientists

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Modification of gamma-aminobutyric acidA receptor binding and function by N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline in vitro and in vivo: effects of aging

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Molindone: a pilot evaluation during the premenstruum

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Multiple human cytochromes contribute to biotransformation of dextromethorphan in-vitro: role of CYP2C9, CYP2C19, CYP2D6, and CYP3A

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Musings on Melanoma

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Musings on Social Media and GIST (Gastrointestinal Stromal Cancer).

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N-demethylation of amitriptyline in vitro: role of cytochrome P-450 3A (CYP3A) isoforms and effect of metabolic inhibitors

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Nefazodone, meta-chlorophenylpiperazine, and their metabolites in vitro: cytochromes mediating transformation, and P450-3A4 inhibitory actions

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Neurochemical and pharmacokinetic correlates of the clinical action of benzodiazepine hypnotic drugs

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New anxiolytics: are they really new?

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Newer antidepressants: further reflections.

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Newer antidepressants: hypotheses and evidence

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Newly marketed medications: ABCs and mind your Qs

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Nomifensine--a farewell and future concerns

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Noninteraction of temazepam and cimetidine

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Not Again: Benzodiazepines Once More Under Attack

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O- and N-demethylation of venlafaxine in vitro by human liver microsomes and by microsomes from cDNA-transfected cells: effect of metabolic inhibitors and SSRI antidepressants

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Obesity effects on nitrazepam disposition

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Ocular (pigmentary) effects of psychotropic drugs

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On guidelines for maximum dosages

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On the psychopharmacology of beta adrenergic blockade

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On top of atopy

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Outliers ??? Noise, Nuisance, or Opportunity? ⬇️

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Overdosage with Pentobarbital and Secobarbital: Assessment of Factors Related to Outcome ⬇️

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Oxaprozin pharmacokinetics in the elderly

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Oxazepam kinetics: effects of age and sex.

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PHENOBARBITAL AND ATROPINE IN COMBINATION, AN ACTIVE CONTROL SUBSTANCE FOR PHENOTHIAZINE RESEARCH

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Panic disorders: clinical update 1984. Epidemiologic and family studies.

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Panic disorders: current perspectives.

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Parental alcoholism as a risk factor in benzodiazepine abuse: a pilot study

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Patterns of violent behavior among schizophrenic inpatients

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Pediatric drug shortages: a deplorable fact and a political problem

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Pharmacodynamic and receptor binding changes during chronic lorazepam administration

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Pharmacodynamics of Benzodiazepines After Single Oral Doses: Kinetic and Physiochemical Correlates ⬇️

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Pharmacoepidemiology

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Pharmacokinetic Aspects of Anxiolytic Drug Therapy ⬇️

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Pharmacokinetic Comparison of Sublingual Lorazepam with Intravenous, Intramuscular, and Oral Lorazepam ⬇️

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Pharmacokinetic Noninteraction of Triazolam and Ethanol ⬇️

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Pharmacokinetic Understanding of Antianxiety Drug Therapy

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Pharmacokinetic and electroencephalographic study of intravenous diazepam, midazolam, and placebo

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Pharmacokinetic aspects of drug therapy in the elderly

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Pharmacokinetic determinants of dynamic differences among three benzodiazepine hypnotics. Flurazepam, temazepam, and triazolam

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Pharmacokinetic determinants of the response to single doses of chlordiazepoxide

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Pharmacokinetic properties of benzodiazepine hypnotics

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Pharmacokinetic properties of zolpidem in elderly and young adults: possible modulation by testosterone in men.

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Pharmacokinetic study of lorazepam overdosage ⬇️

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Pharmacokinetics and Bioavailability of Intravenous, Intramuscular, and Oral Lorazepam in Humans ⬇️

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Pharmacokinetics and Pharmacodynamics of Diphenhydramine 25 mg in Young and Elderly Volunteers ⬇️

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Pharmacokinetics and clinical drug effects in the elderly [proceedings]

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Pharmacokinetics in clinical medicine: oxazepam versus other benzodiazepines

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Pharmacokinetics of Benzodiazepine Hypnotics ⬇️

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Pharmacokinetics of alprazolam

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Pharmacokinetics of benzodiazepine hypnotics

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Pharmacokinetics of benzodiazepines and psychostimulants in children

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Pharmacokinetics of chlordiazepoxide and metabolites following single and multiple oral doses

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Pharmacokinetics of diphenhydramine and a demethylated metabolite following intravenous and oral administration

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Pharmacokinetics of intravenous caffeine: comparison of high-performance liquid chromatographic and gas chromatographic methods

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Pharmacokinetics: the view from Clinical Therapeutics

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Pharmacovigilance and Some Thoughts About What We Eat

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Pharmocokinetics and pharmacodynamics of single-dose triazolam: electroencephalography compared with the Digit-Symbol Substitution Test

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Phase I trials

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Phenacetin O-deethylation by human liver microsomes in vitro: inhibition by chemical probes, SSRI antidepressants, nefazodone and venlafaxine

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Physiologic changes in old age: relation to altered drug disposition

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Physostigmine test in the rabbit syndrome and tardive dyskinesia

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Pilot pharmacokinetic study of brotizolam, a thienodiazepine hypnotic, using electron-capture gas-liquid chromatography

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Placebos and Clinical Therapeutics

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Placebos, Active Placebos, and Clinical Trials

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Plasma alprazolam concentrations. Relation to efficacy and side effects in the treatment of panic disorder

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Plasma and cerebrospinal fluid concentrations of chlordiazepoxide and its metabolites in surgical patients

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Plasma concentrations and clinical effects after single oral doses of prazepam, clorazepate, and diazepam

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Plasma diazepam and desmethyldiazepam concentrations during long-term diazepam therapy

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Plasma levels of trazodone: methodology and applications

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Polypharmacy, Pill Burden, and Optimizing the Medicine Cabinet

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Population pharmacokinetics of methylphenidate in children with attention-deficit hyperactivity disorder

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Population study of triazolam pharmacokinetics

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Possible interaction between fluoxetine and pimozide causing sinus bradycardia

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Potassium, antipsychotic agents, arrhythmias, and sudden death

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Prazepam and Lorazepam, Two New Benzodiazepines ⬇️

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Prazepam, a precursor of desmethyldiazepam

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Preliminary evidence of benzodiazepine subsensitivity in panic disorder

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Preliminary experiences with the treatment of opiate addiction by methadone withdrawal

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Prenatal benzodiazepine administration. II. Lorazepam exposure is associated with decreases in [35S]TBPS binding but not benzodiazepine binding

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Prenatal exposure to benzodiazepine--I. Prenatal exposure to lorazepam in mice alters open-field activity and GABAA receptor function

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Problems of polypharmacy in depression

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Prolongation of drug half-life due to obesity: studies of desmethyldiazepam (clorazepate).

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Prolonged accumulation of diazepam in obesity

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Proof of Feasibility: What a Pilot Study Is and Is Not

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Prophylactic Vaccines, Successes, Errors, and Complications.

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Propranolol??s Psychiatric Side Effects ⬇️

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Protease Inhibitors as Inhibitors of Human Cytochromes P450: High Risk Associated with Ritonavir ⬇️

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Protease inhibitors and drug interactions--an alert

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Psychiatrists' biases: Who get drugs? ⬇️

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Psychiatrists' responses to violence: pharmacologic management of psychiatric inpatients ⬇️

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Psychopharmacologic Investigations in Elderly Volunteers: Effect of Diazepam in Males† ⬇️

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Psychopharmacologic Investigations in Healthy Elderly Volunteers: Effects of Pipradrol-Vitamin (Alertonic) Elixir and Placebo in Relation to Research Design† ⬇️

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Psychopharmacologic Investigations in Healthy Elderly Volunteers: MMPI Depression Scale† ⬇️

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Psychopharmacologic Management of Anxiety in the Cardiac Patient ⬇️

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Psychosis and Psychotherapy

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Psychotherapy and pharmacotherapy in chronic schizophrenia

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Psychotropic drug prescribing in the United States: extent, costs, and expenditures

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Psychotropic drug use in the Boston area. A report from the Boston Collaborative Drug Surveillance Program

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Psychotropic drugs and induced hostility

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Ranitidine does not impair oxidative or conjugative metabolism: noninteraction with antipyrine, diazepam, and lorazepam

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Rapid increase in brain benzodiazepine receptor binding following defeat stress in mice

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Rapid recovery from massive diazepam overdose

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Rating scales for geriatric psychopharmacology--a review

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Rational Psycho-Pharmacology for Patients with Medical Diseases ⬇️

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Rational use of psychotropic drugs II. Antianxiety agents.

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Rational use of psychotropic drugs. II. Antianxiety agents

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Rational use of psychotropic drugs. III. Major tranquilizers

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Rational use of psychotropic drugs. IV. Antidepressants

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Rational use of psychotropic drugs. IV. Antidepressants

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Recent Recall of a Generic Form of Extended-Release Paliperidone

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Reduced benzodiazepine sensitivity in panic disorder

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Reduced clearance of triazolam in old age: relation to antipyrine oxidizing capacity ⬇️

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Reduced single-dose clearance of clobazam in elderly men predicts increased multiple-dose accumulation

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Reflection on the Affordable Care Act (ACA) of 2010

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Reflections on 2013, the beginning of 2014, and the Food and Drug Administration's new expedited approval program known as breakthrough product designation

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Reflections on the Phases of the Moon and the Phases of Drug Development

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Relationship of in vitro data on drug metabolism to in vivo pharmacokinetics and drug interactions: implications for diazepam disposition in humans

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Relationship of plasma and brain concentrations of caffeine and metabolites to benzodiazepine receptor binding and locomotor activity

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Relative contribution of CYP3A to amitriptyline clearance in humans: in vitro and in vivo studies

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Repeated diazepam dosing in cirrhotic patients: cumulation and sedation

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Reporting Currency Values; and Video Abstract Guidelines

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Response of the elderly to psychotrophic drugs: predictable or idiosyncratic?

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Risk Evaluation and Mitigation Strategies (REMS), Pemoline, and What Is a Signal?

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Risk Factors Versus Causes

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Safety Versus Tolerability

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Sandoz Clinical Assessment-Geriatric (SCAG).

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Say "no" to drug testing

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Schizophrenia, oligospermia, and the phenothiazines

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Screening for Aminoacidurias in Psychiatric Inpatients ⬇️

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Sedative effects and impaired learning and recall after single oral doses of lorazepam

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Selective serotonin reuptake inhibitor antidepressants: cardiovascular complications--sorting through findings.

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Selective serotonin reuptake inhibitors and benzodiazepines in panic disorder: A meta-analysis of common side effects in acute treatment

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Self-rated sedation and plasma concentrations of desmethyldiazepam following single doses of clorazepate

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Sensitivity to triazolam in the elderly

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Separate and combined effects of caffeine and alprazolam on motor activity and benzodiazepine receptor binding in vivo

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Serum creatine phosphokinase and aldolase activity in acute schizophrenic patients and their relatives ⬇️

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Serum creatine phosphokinase concentrations after intramuscular chlordiazepoxide and its solvent

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Seven Aphorisms About Therapeutic Relationships and Listening

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Sex differences in diazepam protein binding in patients with renal insufficiency

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Sexual dysfunction associated with mesoridazine besylate (serentil)

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Shades of the patent medicine man.

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Short-term exposure to low-dose ritonavir impairs clearance and enhances adverse effects of trazodone.

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Single Versus Repeated Dosage of the Minor Tranquilizer Chlordiazepoxide (Librium) ⬇️

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Single- and multiple-dose kinetics of oral lorazepam in humans: the predictability of accumulation

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Single-Dose Kinetics of Prazepam, a Precursor of Desmethyldiazepam ⬇️

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Single‐Dose Pharmacokinetics and Pharmacodynamics of Alprazolam in Elderly and Young Subjects ⬇️

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Slow Accumulation and Elimination of Diazepam and Its Active Metabolite With Extended Treatment in the Elderly

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Slow absorption of intramuscular chlordiazepoxide

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Some Comments on Infection Prophylaxis.

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Suggestions for treating drug abusers in a family practice

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Superbugs, Colistin, and Related Issues

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The Ten Cs of Good Clinical Care.

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The cart before the horse? Health insurance reform before health care reform

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The challenge of teaching psychopharmacology and improving clinical practice

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The chronic patient: issues and concerns.

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The clinical choice of sedative-hypnotics

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The diagnosis and treatment of panic disorder in alcoholics: three cases

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The differential effects of chlordiazepoxide and oxazepam on hostility in a small group setting ⬇️

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The effect of age on sildenafil biotransformation in rat and mouse liver microsomes.

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The effect of benztropine on haloperidol-induced dystonia, clinical efficacy and pharmacokinetics: a prospective, double-blind trial

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The liver: a vulnerable helper

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The neuropsychiatric effects of aspartame in normal volunteers

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The observers and the observed: the effects of doing ratings on staff-patient contact patterns

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The pharmacokinetics and pharmacodynamics of sublingual and oral alprazolam in the post-prandial state

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The psychology of hallucinogenic drug discontinuers

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Thoughts About Journals, Altruism, Impact Factors, Marijuana, and the Physician Labeling Rule

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Thyroid function monitoring for lithium-treated patients

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Tissue distribution of diazepam and its metabolite desmethyldiazepam: a human autopsy study

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Too Good to Be True? Aspirin and Schizophrenia ⬇️

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Toxicity of high-dose flurazepam in the elderly ⬇️

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Trazodone kinetics: effect of age, gender, and obesity

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Treating the drug abuser in the ED

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Treatment of Diazepam Withdrawal Syndrome with Propranolol

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Triazolam Kinetics: Interaction with Cimetidine, Propranolol, and the Combination ⬇️

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Triazolam and anterograde amnesia: all is not well in the Z-zone

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Triazolam biotransformation by human liver microsomes in vitro: effects of metabolic inhibitors and clinical confirmation of a predicted interaction with ketoconazole

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Tricyclic Antidepressant Determination in Human Plasma by Gas-Liquid Chromatography Using Nitrogen-Phosphorous Detection: Application to Single-Dose Pharmacokinetic Studies ⬇️

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Trimipramine kinetics and absolute bioavailability: use of gas-liquid chromatography with nitrogen-phosphorus detection

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Tybamate: an examination of its actions in "high" and "low" anxious normals

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Update on Psychotropic Drug Prescribing in the United States: 2014-2015.

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Urgent pharmacotherapy for drug abuse

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Use of benzodiazepines in anxiety disorders

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User unfriendly drugs--fillers, additives, excipients

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Venlafaxine and metabolites are very weak inhibitors of human cytochrome P450-3A isoforms

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Vitamin C prophylaxis and some problems of statistical inference.

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Vitamins C and D

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Water safety, medication disposal, and more: an update.

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Water, water everywhere: but is it safe to drink? Return to a muddy topic.

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What can be done for depression following acute schizophreniform psychosis? ⬇️

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What is depression and who is in depression studies?

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When old ways no longer work: antibiotics and drug development

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When to drool is cool

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Women and Heart Disease

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Word frequency measures of verbal disorders in schizophrenia

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Zolpidem pharmacokinetic properties in young females: influence of smoking and oral contraceptive use.

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Zoonotic Viruses: The Mysterious Leap From Animals to Man

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